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PDB: 4 results

1PWA
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BU of 1pwa by Molmil
Crystal structure of Fibroblast Growth Factor 19
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Fibroblast growth factor-19, GLYCEROL, ...
Authors:Harmer, N.J, Pellegrini, L, Chirgadze, D, Fernandez-Recio, J, Blundell, T.L.
Deposit date:2003-07-01
Release date:2004-01-27
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:The crystal structure of fibroblast growth factor (FGF) 19 reveals novel features of the FGF family and offers a structural basis for its unusual receptor affinity.
Biochemistry, 43, 2004
2P23
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BU of 2p23 by Molmil
Crystal structure of human FGF19
Descriptor: Fibroblast growth factor 19
Authors:Mohammadi, M.
Deposit date:2007-03-06
Release date:2007-04-10
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Molecular insights into the klotho-dependent, endocrine mode of action of fibroblast growth factor 19 subfamily members.
Mol.Cell.Biol., 27, 2007
6KTR
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BU of 6ktr by Molmil
Crystal structure of fibroblast growth factor 19 in complex with Fab
Descriptor: Fibroblast growth factor 19, G1A8-Fab-HC, G1A8-Fab-LC, ...
Authors:Liu, H, Zheng, S, Hou, X, Liu, X, Lv, X, Li, Y, Li, W, Sui, J.
Deposit date:2019-08-28
Release date:2020-07-08
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.59775758 Å)
Cite:Novel Abs targeting the N-terminus of fibroblast growth factor 19 inhibit hepatocellular carcinoma growth without bile-acid-related side-effects.
Cancer Sci., 111, 2020
6NFJ
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Structure of Beta-Klotho in Complex with FGF19 C-terminal peptide
Descriptor: Beta-klotho, Fibroblast growth factor 19, Nanobody 30
Authors:Kuzina, E, Schlessinger, J, Lee, S.
Deposit date:2018-12-20
Release date:2019-04-03
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.19 Å)
Cite:Structures of ligand-occupied beta-Klotho complexes reveal a molecular mechanism underlying endocrine FGF specificity and activity.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019

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