8GLP
| mRNA decoding in human is kinetically and structurally distinct from bacteria (Consensus LSU focused refined structure) | Descriptor: | 1,4-DIAMINOBUTANE, 18S rRNA, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... | Authors: | Holm, M, Natchiar, K.S, Rundlet, E.J, Myasnikov, A.G, Watson, Z.L, Altman, R.B, Blanchard, S.C. | Deposit date: | 2023-03-22 | Release date: | 2023-04-19 | Last modified: | 2023-11-15 | Method: | ELECTRON MICROSCOPY (1.67 Å) | Cite: | mRNA decoding in human is kinetically and structurally distinct from bacteria. Nature, 617, 2023
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8A3D
| Human mature large subunit of the ribosome with eIF6 and homoharringtonine bound | Descriptor: | (3beta)-O~3~-[(2R)-2,6-dihydroxy-2-(2-methoxy-2-oxoethyl)-6-methylheptanoyl]cephalotaxine, 28S ribosomal RNA, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... | Authors: | Faille, A, Warren, A.J, Dent, K.C. | Deposit date: | 2022-06-08 | Release date: | 2023-03-08 | Last modified: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (1.67 Å) | Cite: | The chemical landscape of the human ribosome at 1.67 angstrom resolution. Biorxiv, 2023
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8QOI
| Structure of the human 80S ribosome at 1.9 A resolution - the molecular role of chemical modifications and ions in RNA | Descriptor: | 18S rRNA (1740-MER), 28S rRNA (3773-MER), 40S ribosomal protein S10, ... | Authors: | Holvec, S, Barchet, C, Frechin, L, Hazemann, I, von Loeffelholz, O, Klaholz, B.P. | Deposit date: | 2023-09-29 | Release date: | 2024-06-12 | Last modified: | 2024-08-28 | Method: | ELECTRON MICROSCOPY (1.9 Å) | Cite: | The structure of the human 80S ribosome at 1.9 angstrom resolution reveals the molecular role of chemical modifications and ions in RNA. Nat.Struct.Mol.Biol., 31, 2024
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8YOO
| Cryo-EM structure of the human 80S ribosome with 100 um Tigecycline | Descriptor: | 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ... | Authors: | Li, X, Wang, M, Denk, T, Cheng, J. | Deposit date: | 2024-03-13 | Release date: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (2 Å) | Cite: | Structural basis for differential inhibition of eukaryotic ribosomes by tigecycline. Nat Commun, 15, 2024
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8QFD
| UFL1 E3 ligase bound 60S ribosome | Descriptor: | 28S rRNA, 5.8S rRNA, 5S rRNA, ... | Authors: | Makhlouf, L, Kulathu, Y, Zeqiraj, E. | Deposit date: | 2023-09-04 | Release date: | 2024-02-21 | Last modified: | 2024-04-03 | Method: | ELECTRON MICROSCOPY (2.2 Å) | Cite: | The UFM1 E3 ligase recognizes and releases 60S ribosomes from ER translocons. Nature, 627, 2024
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8YOP
| Cryo-EM structure of the human 80S ribosome with 4 um Tigecycline | Descriptor: | 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ... | Authors: | Li, X, Wang, M, Denk, T, Cheng, J. | Deposit date: | 2024-03-13 | Release date: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (2.2 Å) | Cite: | Structural basis for differential inhibition of eukaryotic ribosomes by tigecycline. Nat Commun, 15, 2024
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8JDK
| Structure of the Human cytoplasmic Ribosome with human tRNA Asp(ManQ34) and mRNA(GAU) | Descriptor: | 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... | Authors: | Ishiguro, K, Yokoyama, T, Shirouzu, M, Suzuki, T. | Deposit date: | 2023-05-14 | Release date: | 2023-12-06 | Last modified: | 2023-12-27 | Method: | ELECTRON MICROSCOPY (2.26 Å) | Cite: | Glycosylated queuosines in tRNAs optimize translational rate and post-embryonic growth. Cell, 186, 2023
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8G5Y
| mRNA decoding in human is kinetically and structurally distinct from bacteria (IC state) | Descriptor: | 1,4-DIAMINOBUTANE, 18S rRNA, 28S rRNA, ... | Authors: | Holm, M, Natchiar, K.S, Rundlet, E.J, Myasnikov, A.G, Altman, R.B, Blanchard, S.C. | Deposit date: | 2023-02-14 | Release date: | 2023-04-19 | Last modified: | 2023-11-15 | Method: | ELECTRON MICROSCOPY (2.29 Å) | Cite: | mRNA decoding in human is kinetically and structurally distinct from bacteria. Nature, 617, 2023
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7OW7
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8K2C
| Cryo-EM structure of the human 80S ribosome with Tigecycline | Descriptor: | 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ... | Authors: | Li, X, Wang, M, Cheng, J. | Deposit date: | 2023-07-12 | Release date: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (2.4 Å) | Cite: | Structural basis for differential inhibition of eukaryotic ribosomes by tigecycline. Nat Commun, 15, 2024
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8XSX
| Cryo-EM structure of the human 80S ribosome with Tigecycline, E-tRNA, SERBP1 and eEF2 | Descriptor: | 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ... | Authors: | Li, X, Wang, M, Cheng, J. | Deposit date: | 2024-01-10 | Release date: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (2.4 Å) | Cite: | Structural basis for differential inhibition of eukaryotic ribosomes by tigecycline. Nat Commun, 15, 2024
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8JDL
| Structure of the Human cytoplasmic Ribosome with human tRNA Tyr(GalQ34) and mRNA(UAU) (non-rotated state) | Descriptor: | 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... | Authors: | Ishiguro, K, Yokoyama, T, Shirouzu, M, Suzuki, T. | Deposit date: | 2023-05-14 | Release date: | 2023-12-06 | Last modified: | 2023-12-27 | Method: | ELECTRON MICROSCOPY (2.42 Å) | Cite: | Glycosylated queuosines in tRNAs optimize translational rate and post-embryonic growth. Cell, 186, 2023
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8FLE
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8JDJ
| Structure of the Human cytoplasmic Ribosome with human tRNA Asp(Q34) and mRNA(GAU) | Descriptor: | 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... | Authors: | Ishiguro, K, Yokoyama, T, Shirouzu, M, Suzuki, T. | Deposit date: | 2023-05-14 | Release date: | 2023-12-06 | Last modified: | 2023-12-27 | Method: | ELECTRON MICROSCOPY (2.5 Å) | Cite: | Glycosylated queuosines in tRNAs optimize translational rate and post-embryonic growth. Cell, 186, 2023
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7XNY
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8G60
| mRNA decoding in human is kinetically and structurally distinct from bacteria (CR state) | Descriptor: | 1,4-DIAMINOBUTANE, 18S rRNA, 28S rRNA, ... | Authors: | Holm, M, Natchiar, K.S, Rundlet, E.J, Myasnikov, A.G, Altman, R.B, Blanchard, S.C. | Deposit date: | 2023-02-14 | Release date: | 2023-04-19 | Last modified: | 2023-11-15 | Method: | ELECTRON MICROSCOPY (2.54 Å) | Cite: | mRNA decoding in human is kinetically and structurally distinct from bacteria. Nature, 617, 2023
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8FL7
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8FLB
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8IFE
| Arbekacin-added human 80S ribosome | Descriptor: | 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... | Authors: | Tomono, J, Asano, K, Chiashi, T, Tanaka, Y, Yokoyama, T. | Deposit date: | 2023-02-17 | Release date: | 2024-02-14 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (2.57 Å) | Cite: | Direct visualization of ribosomes in the cell-free system revealed the functional evolution of aminoglycoside. J.Biochem., 175, 2024
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8FLD
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9GMO
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8IFD
| Dibekacin-added human 80S ribosome | Descriptor: | 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... | Authors: | Tomono, J, Asano, K, Chiashi, T, Tanaka, Y, Yokoyama, T. | Deposit date: | 2023-02-17 | Release date: | 2024-02-14 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (2.59 Å) | Cite: | Direct visualization of ribosomes in the cell-free system revealed the functional evolution of aminoglycoside. J.Biochem., 175, 2024
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6ZMI
| SARS-CoV-2 Nsp1 bound to the human LYAR-80S ribosome complex | Descriptor: | 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... | Authors: | Thoms, M, Buschauer, R, Ameismeier, M, Denk, T, Kratzat, H, Mackens-Kiani, T, Cheng, J, Berninghausen, O, Becker, T, Beckmann, R. | Deposit date: | 2020-07-02 | Release date: | 2020-08-19 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (2.6 Å) | Cite: | Structural basis for translational shutdown and immune evasion by the Nsp1 protein of SARS-CoV-2. Science, 369, 2020
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8FL6
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8FLA
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