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PDB: 81 results

8GLP
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BU of 8glp by Molmil
mRNA decoding in human is kinetically and structurally distinct from bacteria (Consensus LSU focused refined structure)
Descriptor: 1,4-DIAMINOBUTANE, 18S rRNA, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ...
Authors:Holm, M, Natchiar, K.S, Rundlet, E.J, Myasnikov, A.G, Watson, Z.L, Altman, R.B, Blanchard, S.C.
Deposit date:2023-03-22
Release date:2023-04-19
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (1.67 Å)
Cite:mRNA decoding in human is kinetically and structurally distinct from bacteria.
Nature, 617, 2023
8A3D
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BU of 8a3d by Molmil
Human mature large subunit of the ribosome with eIF6 and homoharringtonine bound
Descriptor: (3beta)-O~3~-[(2R)-2,6-dihydroxy-2-(2-methoxy-2-oxoethyl)-6-methylheptanoyl]cephalotaxine, 28S ribosomal RNA, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ...
Authors:Faille, A, Warren, A.J, Dent, K.C.
Deposit date:2022-06-08
Release date:2023-03-08
Last modified:2024-07-24
Method:ELECTRON MICROSCOPY (1.67 Å)
Cite:The chemical landscape of the human ribosome at 1.67 angstrom resolution.
Biorxiv, 2023
8QOI
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BU of 8qoi by Molmil
Structure of the human 80S ribosome at 1.9 A resolution - the molecular role of chemical modifications and ions in RNA
Descriptor: 18S rRNA (1740-MER), 28S rRNA (3773-MER), 40S ribosomal protein S10, ...
Authors:Holvec, S, Barchet, C, Frechin, L, Hazemann, I, von Loeffelholz, O, Klaholz, B.P.
Deposit date:2023-09-29
Release date:2024-06-12
Last modified:2024-08-28
Method:ELECTRON MICROSCOPY (1.9 Å)
Cite:The structure of the human 80S ribosome at 1.9 angstrom resolution reveals the molecular role of chemical modifications and ions in RNA.
Nat.Struct.Mol.Biol., 31, 2024
8YOO
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BU of 8yoo by Molmil
Cryo-EM structure of the human 80S ribosome with 100 um Tigecycline
Descriptor: 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ...
Authors:Li, X, Wang, M, Denk, T, Cheng, J.
Deposit date:2024-03-13
Release date:2024-07-10
Method:ELECTRON MICROSCOPY (2 Å)
Cite:Structural basis for differential inhibition of eukaryotic ribosomes by tigecycline.
Nat Commun, 15, 2024
8QFD
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BU of 8qfd by Molmil
UFL1 E3 ligase bound 60S ribosome
Descriptor: 28S rRNA, 5.8S rRNA, 5S rRNA, ...
Authors:Makhlouf, L, Kulathu, Y, Zeqiraj, E.
Deposit date:2023-09-04
Release date:2024-02-21
Last modified:2024-04-03
Method:ELECTRON MICROSCOPY (2.2 Å)
Cite:The UFM1 E3 ligase recognizes and releases 60S ribosomes from ER translocons.
Nature, 627, 2024
8YOP
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BU of 8yop by Molmil
Cryo-EM structure of the human 80S ribosome with 4 um Tigecycline
Descriptor: 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ...
Authors:Li, X, Wang, M, Denk, T, Cheng, J.
Deposit date:2024-03-13
Release date:2024-07-10
Method:ELECTRON MICROSCOPY (2.2 Å)
Cite:Structural basis for differential inhibition of eukaryotic ribosomes by tigecycline.
Nat Commun, 15, 2024
8JDK
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BU of 8jdk by Molmil
Structure of the Human cytoplasmic Ribosome with human tRNA Asp(ManQ34) and mRNA(GAU)
Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ...
Authors:Ishiguro, K, Yokoyama, T, Shirouzu, M, Suzuki, T.
Deposit date:2023-05-14
Release date:2023-12-06
Last modified:2023-12-27
Method:ELECTRON MICROSCOPY (2.26 Å)
Cite:Glycosylated queuosines in tRNAs optimize translational rate and post-embryonic growth.
Cell, 186, 2023
8G5Y
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BU of 8g5y by Molmil
mRNA decoding in human is kinetically and structurally distinct from bacteria (IC state)
Descriptor: 1,4-DIAMINOBUTANE, 18S rRNA, 28S rRNA, ...
Authors:Holm, M, Natchiar, K.S, Rundlet, E.J, Myasnikov, A.G, Altman, R.B, Blanchard, S.C.
Deposit date:2023-02-14
Release date:2023-04-19
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (2.29 Å)
Cite:mRNA decoding in human is kinetically and structurally distinct from bacteria.
Nature, 617, 2023
7OW7
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BU of 7ow7 by Molmil
EIF6-bound large subunit of the human ribosome
Descriptor: 28S rRNA, 5.8S ribosomal RNA, 5S rRNA, ...
Authors:Faille, A, Warren, A.J.
Deposit date:2021-06-16
Release date:2022-10-05
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (2.4 Å)
Cite:Structure of human EIF6-bound large ribosomal subunit
To Be Published
8K2C
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BU of 8k2c by Molmil
Cryo-EM structure of the human 80S ribosome with Tigecycline
Descriptor: 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ...
Authors:Li, X, Wang, M, Cheng, J.
Deposit date:2023-07-12
Release date:2024-07-10
Method:ELECTRON MICROSCOPY (2.4 Å)
Cite:Structural basis for differential inhibition of eukaryotic ribosomes by tigecycline.
Nat Commun, 15, 2024
8XSX
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BU of 8xsx by Molmil
Cryo-EM structure of the human 80S ribosome with Tigecycline, E-tRNA, SERBP1 and eEF2
Descriptor: 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ...
Authors:Li, X, Wang, M, Cheng, J.
Deposit date:2024-01-10
Release date:2024-07-10
Method:ELECTRON MICROSCOPY (2.4 Å)
Cite:Structural basis for differential inhibition of eukaryotic ribosomes by tigecycline.
Nat Commun, 15, 2024
8JDL
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BU of 8jdl by Molmil
Structure of the Human cytoplasmic Ribosome with human tRNA Tyr(GalQ34) and mRNA(UAU) (non-rotated state)
Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ...
Authors:Ishiguro, K, Yokoyama, T, Shirouzu, M, Suzuki, T.
Deposit date:2023-05-14
Release date:2023-12-06
Last modified:2023-12-27
Method:ELECTRON MICROSCOPY (2.42 Å)
Cite:Glycosylated queuosines in tRNAs optimize translational rate and post-embryonic growth.
Cell, 186, 2023
8FLE
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BU of 8fle by Molmil
Human nuclear pre-60S ribosomal subunit (State L2)
Descriptor: 28S rRNA, 5.8S rRNA, 5S rRNA, ...
Authors:Vanden Broeck, A, Klinge, S.
Deposit date:2022-12-21
Release date:2023-07-12
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (2.48 Å)
Cite:Principles of human pre-60 S biogenesis.
Science, 381, 2023
8JDJ
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BU of 8jdj by Molmil
Structure of the Human cytoplasmic Ribosome with human tRNA Asp(Q34) and mRNA(GAU)
Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ...
Authors:Ishiguro, K, Yokoyama, T, Shirouzu, M, Suzuki, T.
Deposit date:2023-05-14
Release date:2023-12-06
Last modified:2023-12-27
Method:ELECTRON MICROSCOPY (2.5 Å)
Cite:Glycosylated queuosines in tRNAs optimize translational rate and post-embryonic growth.
Cell, 186, 2023
7XNY
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BU of 7xny by Molmil
High resolution cry-EM structure of the human 80S ribosome from SNORD127+/- Kasumi-1 cells
Descriptor: 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ...
Authors:Cheng, J, Beckmann, R.
Deposit date:2022-04-30
Release date:2023-04-05
Method:ELECTRON MICROSCOPY (2.5 Å)
Cite:A Dynamic rRNA Ribomethylome Drives Stemness in Acute Myeloid Leukemia.
Cancer Discov, 13, 2023
8G60
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BU of 8g60 by Molmil
mRNA decoding in human is kinetically and structurally distinct from bacteria (CR state)
Descriptor: 1,4-DIAMINOBUTANE, 18S rRNA, 28S rRNA, ...
Authors:Holm, M, Natchiar, K.S, Rundlet, E.J, Myasnikov, A.G, Altman, R.B, Blanchard, S.C.
Deposit date:2023-02-14
Release date:2023-04-19
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (2.54 Å)
Cite:mRNA decoding in human is kinetically and structurally distinct from bacteria.
Nature, 617, 2023
8FL7
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BU of 8fl7 by Molmil
Human nuclear pre-60S ribosomal subunit (State J2)
Descriptor: 28S rRNA, 5.8S rRNA, 5S rRNA, ...
Authors:Vanden Broeck, A, Klinge, S.
Deposit date:2022-12-21
Release date:2023-07-12
Last modified:2023-07-26
Method:ELECTRON MICROSCOPY (2.55 Å)
Cite:Principles of human pre-60 S biogenesis.
Science, 381, 2023
8FLB
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BU of 8flb by Molmil
Human nuclear pre-60S ribosomal subunit (State K2)
Descriptor: 28S rRNA, 5.8S rRNA, 5S rRNA, ...
Authors:Vanden Broeck, A, Klinge, S.
Deposit date:2022-12-21
Release date:2023-07-12
Last modified:2023-07-26
Method:ELECTRON MICROSCOPY (2.55 Å)
Cite:Principles of human pre-60 S biogenesis.
Science, 381, 2023
8IFE
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BU of 8ife by Molmil
Arbekacin-added human 80S ribosome
Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ...
Authors:Tomono, J, Asano, K, Chiashi, T, Tanaka, Y, Yokoyama, T.
Deposit date:2023-02-17
Release date:2024-02-14
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (2.57 Å)
Cite:Direct visualization of ribosomes in the cell-free system revealed the functional evolution of aminoglycoside.
J.Biochem., 175, 2024
8FLD
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BU of 8fld by Molmil
Human nuclear pre-60S ribosomal subunit (State L1)
Descriptor: 28S rRNA, 5.8S rRNA, 5S rRNA, ...
Authors:Vanden Broeck, A, Klinge, S.
Deposit date:2022-12-21
Release date:2023-07-12
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (2.58 Å)
Cite:Principles of human pre-60 S biogenesis.
Science, 381, 2023
9GMO
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BU of 9gmo by Molmil
eIF6-bound pre-60S large ribosomal subunit incorporating mutant uL16
Descriptor: 28S rRNA, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 5.8S rRNA, ...
Authors:Bothe, A, Ban, N, Kostova, K.
Deposit date:2024-08-29
Release date:2024-10-02
Method:ELECTRON MICROSCOPY (2.59 Å)
Cite:ZNF574 is a Quality Control Factor For Defective Ribosome Biogenesis Intermediates.
Biorxiv, 2024
8IFD
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BU of 8ifd by Molmil
Dibekacin-added human 80S ribosome
Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ...
Authors:Tomono, J, Asano, K, Chiashi, T, Tanaka, Y, Yokoyama, T.
Deposit date:2023-02-17
Release date:2024-02-14
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (2.59 Å)
Cite:Direct visualization of ribosomes in the cell-free system revealed the functional evolution of aminoglycoside.
J.Biochem., 175, 2024
6ZMI
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BU of 6zmi by Molmil
SARS-CoV-2 Nsp1 bound to the human LYAR-80S ribosome complex
Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ...
Authors:Thoms, M, Buschauer, R, Ameismeier, M, Denk, T, Kratzat, H, Mackens-Kiani, T, Cheng, J, Berninghausen, O, Becker, T, Beckmann, R.
Deposit date:2020-07-02
Release date:2020-08-19
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:Structural basis for translational shutdown and immune evasion by the Nsp1 protein of SARS-CoV-2.
Science, 369, 2020
8FL6
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BU of 8fl6 by Molmil
Human nuclear pre-60S ribosomal subunit (State J1)
Descriptor: 28S rRNA, 5.8S rRNA, 5S rRNA, ...
Authors:Vanden Broeck, A, Klinge, S.
Deposit date:2022-12-21
Release date:2023-07-12
Last modified:2023-07-19
Method:ELECTRON MICROSCOPY (2.62 Å)
Cite:Principles of human pre-60 S biogenesis.
Science, 381, 2023
8FLA
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BU of 8fla by Molmil
Human nuclear pre-60S ribosomal subunit (State K1)
Descriptor: 28S rRNA, 5.8S rRNA, 5S rRNA, ...
Authors:Vanden Broeck, A, Klinge, S.
Deposit date:2022-12-21
Release date:2023-07-12
Last modified:2023-07-26
Method:ELECTRON MICROSCOPY (2.63 Å)
Cite:Principles of human pre-60 S biogenesis.
Science, 381, 2023

 

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