7O9M
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![BU of 7o9m by Molmil](/molmil-images/mine/7o9m) | Human mitochondrial ribosome large subunit assembly intermediate with MTERF4-NSUN4, MRM2, MTG1 and the MALSU module | Descriptor: | 16S rRNA, 39S ribosomal protein L10, mitochondrial, ... | Authors: | Valentin Gese, G, Hallberg, B.M. | Deposit date: | 2021-04-16 | Release date: | 2021-06-30 | Method: | ELECTRON MICROSCOPY (2.5 Å) | Cite: | Structural basis for late maturation steps of the human mitoribosomal large subunit. Nat Commun, 12, 2021
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8K2A
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![BU of 8k2a by Molmil](/molmil-images/mine/8k2a) | Cryo-EM structure of the human 55S mitoribosome with Tigecycline | Descriptor: | 12S rRNA, 16S rRNA, 39S ribosomal protein L22, ... | Authors: | Li, X, Wang, M, Cheng, J. | Deposit date: | 2023-07-12 | Release date: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Structural basis for differential inhibition of eukaryotic ribosomes by tigecycline. Nat Commun, 15, 2024
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6VMI
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![BU of 6vmi by Molmil](/molmil-images/mine/6vmi) | Structure of the human mitochondrial ribosome-EF-G1 complex (ClassIII) | Descriptor: | 12s rRNA, 16s rRNA, 28S ribosomal protein S10, ... | Authors: | Sharma, M.R, Koripella, R.K, Agrawal, R.K. | Deposit date: | 2020-01-28 | Release date: | 2020-08-05 | Last modified: | 2021-02-17 | Method: | ELECTRON MICROSCOPY (2.96 Å) | Cite: | Structures of the human mitochondrial ribosome bound to EF-G1 reveal distinct features of mitochondrial translation elongation. Nat Commun, 11, 2020
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6VLZ
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![BU of 6vlz by Molmil](/molmil-images/mine/6vlz) | Structure of the human mitochondrial ribosome-EF-G1 complex (ClassI) | Descriptor: | 12s rRNA, 16s rRNA, 28S ribosomal protein S10, ... | Authors: | Sharma, M.R, Koripella, R.K, Agrawal, R.K. | Deposit date: | 2020-01-27 | Release date: | 2020-08-05 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (2.97 Å) | Cite: | Structures of the human mitochondrial ribosome bound to EF-G1 reveal distinct features of mitochondrial translation elongation. Nat Commun, 11, 2020
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8XT3
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![BU of 8xt3 by Molmil](/molmil-images/mine/8xt3) | Cryo-EM structure of the human 39S mitoribosome with 10uM Tigecycline | Descriptor: | 16s rRNA, 39S ribosomal protein L22, mitochondrial, ... | Authors: | Li, X, Wang, M, Cheng, J. | Deposit date: | 2024-01-10 | Release date: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Structural basis for differential inhibition of eukaryotic ribosomes by tigecycline. Nat Commun, 15, 2024
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8XT1
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![BU of 8xt1 by Molmil](/molmil-images/mine/8xt1) | Cryo-EM structure of the human 39S mitoribosome with 5uM Tigecycline | Descriptor: | 16s rRNA, 39S ribosomal protein L22, mitochondrial, ... | Authors: | Li, X, Wang, M, Cheng, J. | Deposit date: | 2024-01-10 | Release date: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Structural basis for differential inhibition of eukaryotic ribosomes by tigecycline. Nat Commun, 15, 2024
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7O9K
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![BU of 7o9k by Molmil](/molmil-images/mine/7o9k) | Human mitochondrial ribosome large subunit assembly intermediate with MTERF4-NSUN4, MRM2, MTG1, the MALSU module, GTPBP5 and mtEF-Tu | Descriptor: | 16S rRNA, 39S ribosomal protein L10, mitochondrial, ... | Authors: | Valentin Gese, G, Hallberg, B.M. | Deposit date: | 2021-04-16 | Release date: | 2021-06-30 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Structural basis for late maturation steps of the human mitoribosomal large subunit. Nat Commun, 12, 2021
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7A5J
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![BU of 7a5j by Molmil](/molmil-images/mine/7a5j) | Structure of the split human mitoribosomal large subunit with P-and E-site mt-tRNAs | Descriptor: | 16S rRNA, 39S ribosomal protein L10, mitochondrial, ... | Authors: | Desai, N, Yang, H, Chandrasekaran, V, Kazi, R, Minczuk, M, Ramakrishnan, V. | Deposit date: | 2020-08-21 | Release date: | 2020-12-23 | Last modified: | 2023-03-15 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Elongational stalling activates mitoribosome-associated quality control. Science, 370, 2020
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7L20
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![BU of 7l20 by Molmil](/molmil-images/mine/7l20) | |
8XT0
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![BU of 8xt0 by Molmil](/molmil-images/mine/8xt0) | Cryo-EM structure of the human 55S mitoribosome with 5um Tigecycline | Descriptor: | 12s rRNA, 16s rRNA, 39S ribosomal protein L22, ... | Authors: | Li, X, Wang, M, Cheng, J. | Deposit date: | 2024-01-10 | Release date: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Structural basis for differential inhibition of eukaryotic ribosomes by tigecycline. Nat Commun, 15, 2024
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8XT2
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![BU of 8xt2 by Molmil](/molmil-images/mine/8xt2) | Cryo-EM structure of the human 55S mitoribosome with 10uM Tigecycline | Descriptor: | 12s rRNA, 16s rRNA, 39S ribosomal protein L22, ... | Authors: | Li, X, Wang, M, Cheng, J. | Deposit date: | 2024-01-10 | Release date: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structural basis for differential inhibition of eukaryotic ribosomes by tigecycline. Nat Commun, 15, 2024
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7A5H
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![BU of 7a5h by Molmil](/molmil-images/mine/7a5h) | Structure of the split human mitoribosomal large subunit with rescue factors mtRF-R and MTRES1 | Descriptor: | 16S rRNA, 39S ribosomal protein L10, mitochondrial, ... | Authors: | Desai, N, Yang, H, Chandrasekaran, V, Kazi, R, Minczuk, M, Ramakrishnan, V. | Deposit date: | 2020-08-21 | Release date: | 2020-12-23 | Last modified: | 2023-03-01 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Elongational stalling activates mitoribosome-associated quality control. Science, 370, 2020
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3J7Y
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![BU of 3j7y by Molmil](/molmil-images/mine/3j7y) | Structure of the large ribosomal subunit from human mitochondria | Descriptor: | 16S rRNA, ADENOSINE MONOPHOSPHATE, CRIF1, ... | Authors: | Brown, A, Amunts, A, Bai, X.C, Sugimoto, Y, Edwards, P.C, Murshudov, G, Scheres, S.H.W, Ramakrishnan, V. | Deposit date: | 2014-08-26 | Release date: | 2014-10-15 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structure of the large ribosomal subunit from human mitochondria. Science, 346, 2014
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8K2B
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![BU of 8k2b by Molmil](/molmil-images/mine/8k2b) | Cryo-EM structure of the human 39S mitoribosome with Tigecycline | Descriptor: | 16s rRNA, 39S ribosomal protein L22, mitochondrial, ... | Authors: | Li, X, Wang, M, Cheng, J. | Deposit date: | 2023-07-12 | Release date: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structural basis for differential inhibition of eukaryotic ribosomes by tigecycline. Nat Commun, 15, 2024
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7L08
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![BU of 7l08 by Molmil](/molmil-images/mine/7l08) | Cryo-EM structure of the human 55S mitoribosome-RRFmt complex. | Descriptor: | 12S rRNA, 16S RRNA, 28S ribosomal protein S10, ... | Authors: | Koripella, R, Agrawal, E.K, Deep, A, Agrawal, R.K. | Deposit date: | 2020-12-11 | Release date: | 2021-05-12 | Last modified: | 2021-12-01 | Method: | ELECTRON MICROSCOPY (3.49 Å) | Cite: | Distinct mechanisms of the human mitoribosome recycling and antibiotic resistance. Nat Commun, 12, 2021
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3J9M
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![BU of 3j9m by Molmil](/molmil-images/mine/3j9m) | Structure of the human mitochondrial ribosome (class 1) | Descriptor: | 12S rRNA, 16S rRNA, E-site tRNA, ... | Authors: | Amunts, A, Brown, A, Toots, J, Scheres, S.H, Ramakrishnan, V. | Deposit date: | 2015-02-08 | Release date: | 2015-04-15 | Last modified: | 2018-07-18 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Ribosome. The structure of the human mitochondrial ribosome. Science, 348, 2015
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7A5I
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![BU of 7a5i by Molmil](/molmil-images/mine/7a5i) | Structure of the human mitoribosome with A- P-and E-site mt-tRNAs | Descriptor: | 12S rRNA, 16S rRNA, 28S ribosomal protein S10, ... | Authors: | Desai, N, Yang, H, Chandrasekaran, V, Kazi, R, Minczuk, M, Ramakrishnan, V. | Deposit date: | 2020-08-21 | Release date: | 2020-12-23 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Elongational stalling activates mitoribosome-associated quality control. Science, 370, 2020
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7A5K
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![BU of 7a5k by Molmil](/molmil-images/mine/7a5k) | Structure of the human mitoribosome in the post translocation state bound to mtEF-G1 | Descriptor: | 12S rRNA, 16S rRNA, 28S ribosomal protein S10, ... | Authors: | Desai, N, Yang, H, Chandrasekaran, V, Kazi, R, Minczuk, M, Ramakrishnan, V. | Deposit date: | 2020-08-21 | Release date: | 2020-12-23 | Last modified: | 2022-12-07 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Elongational stalling activates mitoribosome-associated quality control. Science, 370, 2020
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6I9R
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![BU of 6i9r by Molmil](/molmil-images/mine/6i9r) | Large subunit of the human mitochondrial ribosome in complex with Virginiamycin M and Quinupristin | Descriptor: | 16S rRNA, 39S ribosomal protein L10, mitochondrial, ... | Authors: | Modelska, A, Aibara, S, Amunts, A. | Deposit date: | 2018-11-25 | Release date: | 2020-07-08 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Inhibition of mitochondrial translation suppresses glioblastoma stem cell growth. Cell Rep, 35, 2021
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6ZS9
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![BU of 6zs9 by Molmil](/molmil-images/mine/6zs9) | Human mitochondrial ribosome in complex with ribosome recycling factor | Descriptor: | 12S rRNA, 16S rRNA, 28S ribosomal protein S10, ... | Authors: | Aibara, S, Singh, V, Modelska, A, Amunts, A. | Deposit date: | 2020-07-15 | Release date: | 2020-10-14 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Structural basis of mitochondrial translation. Elife, 9, 2020
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