6N9B
 
 | | FtsY-NG ultra high-resolution | | Descriptor: | ACETATE ION, Signal recognition particle receptor FtsY | | Authors: | Ataide, S.F, Faoro, C. | | Deposit date: | 2018-12-02 | | Release date: | 2019-10-09 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (1.219 Å) | | Cite: | Structural insights into the G-loop dynamics of E. coli FtsY NG domain.
J.Struct.Biol., 208, 2019
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6N5J
 | | FtsY-NG high-resolution | | Descriptor: | ACETATE ION, AMMONIUM ION, Signal recognition particle receptor FtsY | | Authors: | Ataide, S.F, Faoro, C. | | Deposit date: | 2018-11-22 | | Release date: | 2019-10-09 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (1.37 Å) | | Cite: | Structural insights into the G-loop dynamics of E. coli FtsY NG domain.
J.Struct.Biol., 208, 2019
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6CQP
 | | High resolution crystal structure of FtsY-NG domain of E. coli | | Descriptor: | GLYCEROL, SODIUM ION, Signal recognition particle receptor FtsY | | Authors: | Faoro, C, Ataide, S.F. | | Deposit date: | 2018-03-15 | | Release date: | 2018-08-22 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (1.446 Å) | | Cite: | Discovery of fragments that target key interactions in the signal recognition particle (SRP) as potential leads for a new class of antibiotics.
PLoS ONE, 13, 2018
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6N5I
 | | FtsY-NG high-resolution | | Descriptor: | GLYCEROL, POTASSIUM ION, Signal recognition particle receptor FtsY | | Authors: | Ataide, S.F, Faoro, C. | | Deposit date: | 2018-11-21 | | Release date: | 2019-10-09 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (1.498 Å) | | Cite: | Structural insights into the G-loop dynamics of E. coli FtsY NG domain.
J.Struct.Biol., 208, 2019
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6NC1
 | | FtsY-NG high-resolution | | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, POTASSIUM ION, ... | | Authors: | Ataide, S.F, Faoro, C. | | Deposit date: | 2018-12-10 | | Release date: | 2019-10-23 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (1.598 Å) | | Cite: | Structural insights into the G-loop dynamics of E. coli FtsY NG domain.
J.Struct.Biol., 208, 2019
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2YHS
 | | Structure of the E. coli SRP receptor FtsY | | Descriptor: | 1,2-ETHANEDIOL, CELL DIVISION PROTEIN FTSY | | Authors: | Stjepanovic, G, Bange, G, Wild, K, Sinning, I. | | Deposit date: | 2011-05-05 | | Release date: | 2011-05-18 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Lipids Trigger a Conformational Switch that Regulates Signal Recognition Particle (Srp)-Mediated Protein Targeting.
J.Biol.Chem., 286, 2011
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6NC4
 | | FtsY-NG high-resolution | | Descriptor: | ACETATE ION, AMMONIUM ION, GLYCEROL, ... | | Authors: | Ataide, S.F, Faoro, C. | | Deposit date: | 2018-12-10 | | Release date: | 2019-10-23 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Structural insights into the G-loop dynamics of E. coli FtsY NG domain.
J.Struct.Biol., 208, 2019
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5NIY
 | | Signal recognition particle-docking protein FtsY | | Descriptor: | PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Signal recognition particle-docking protein FtsY | | Authors: | Kempf, G, Stjepanovic, G, Lapouge, K, Sinning, I. | | Deposit date: | 2017-03-27 | | Release date: | 2018-10-10 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | The Escherichia coli SRP Receptor Forms a Homodimer at the Membrane.
Structure, 26, 2018
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6CS8
 | | High resolution crystal structure of FtsY-NG domain of E. coli | | Descriptor: | 1H-indole-6-carbonitrile, SODIUM ION, Signal recognition particle receptor FtsY | | Authors: | Faoro, C, Ataide, S.F. | | Deposit date: | 2018-03-19 | | Release date: | 2018-08-22 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (1.749 Å) | | Cite: | Discovery of fragments that target key interactions in the signal recognition particle (SRP) as potential leads for a new class of antibiotics.
PLoS ONE, 13, 2018
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6CVD
 | | High resolution crystal structure of FtsY-NG domain of E. coli bound to fragment 1 | | Descriptor: | AMMONIUM ION, SODIUM ION, Signal recognition particle receptor FtsY, ... | | Authors: | Faoro, C, Ataide, S.F, Kwan, A, Wilkinson-White, L. | | Deposit date: | 2018-03-27 | | Release date: | 2018-08-22 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (1.78 Å) | | Cite: | Discovery of fragments that target key interactions in the signal recognition particle (SRP) as potential leads for a new class of antibiotics.
PLoS ONE, 13, 2018
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6DLX
 | | FtsY-NG domain bound to fragment 3. | | Descriptor: | 4-bromo-2,5-dimethoxyaniline, AMMONIUM ION, DI(HYDROXYETHYL)ETHER, ... | | Authors: | Ataide, F.S, Faoro, C. | | Deposit date: | 2018-06-04 | | Release date: | 2018-08-22 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (1.848 Å) | | Cite: | Discovery of fragments that target key interactions in the signal recognition particle (SRP) as potential leads for a new class of antibiotics.
PLoS ONE, 13, 2018
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6N6N
 | | FtsY-NG high-resolution | | Descriptor: | ACETATE ION, GLYCEROL, MAGNESIUM ION, ... | | Authors: | Ataide, S.F, Faoro, C. | | Deposit date: | 2018-11-26 | | Release date: | 2019-10-09 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (1.877 Å) | | Cite: | Structural insights into the G-loop dynamics of E. coli FtsY NG domain.
J.Struct.Biol., 208, 2019
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2QY9
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6FPK
 | | Co-translational folding intermediate dictates membrane targeting of the signal recognition particle (SRP)- receptor | | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, Signal recognition particle receptor FtsY | | Authors: | Karniel, A, Mrusek, D, Steinchen, W, Dym, O, Bange, G, Bibi, E. | | Deposit date: | 2018-02-11 | | Release date: | 2018-05-09 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Co-translational Folding Intermediate Dictates Membrane Targeting of the Signal Recognition Particle Receptor.
J. Mol. Biol., 430, 2018
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6FQD
 | | Escherichia Coli Signal Recognition Particle Receptor FtsY NGdN1 | | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, POTASSIUM ION, Signal recognition particle receptor FtsY | | Authors: | Mrusek, D. | | Deposit date: | 2018-02-13 | | Release date: | 2018-05-09 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.10000563 Å) | | Cite: | Co-translational Folding Intermediate Dictates Membrane Targeting of the Signal Recognition Particle Receptor.
J. Mol. Biol., 430, 2018
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1FTS
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7O9H
 | | Escherichia coli FtsY in complex with pppGpp | | Descriptor: | Signal recognition particle receptor FtsY, guanosine 5'-(tetrahydrogen triphosphate) 3'-(trihydrogen diphosphate) | | Authors: | Czech, L, Mais, C.-N, Bange, G. | | Deposit date: | 2021-04-16 | | Release date: | 2022-02-02 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Inhibition of SRP-dependent protein secretion by the bacterial alarmone (p)ppGpp.
Nat Commun, 13, 2022
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4C7O
 | | The structural basis of FtsY recruitment and GTPase activation by SRP RNA | | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, SIGNAL RECOGNITION PARTICLE PROTEIN, ... | | Authors: | Voigts-Hoffmann, F, Schmitz, N, Shen, K, Shan, S.O, Ataide, S.F, Ban, N. | | Deposit date: | 2013-09-23 | | Release date: | 2013-11-20 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | The Structural Basis of Ftsy Recruitment and Gtpase Activation by Srp RNA
Mol.Cell, 52, 2013
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6FPR
 | | Co-translational folding intermediate dictates membrane targeting of the signal recognition particle (SRP)- receptor | | Descriptor: | Signal recognition particle receptor FtsY | | Authors: | Karniel, A, Mrusek, D, Steinchen, W, Dym, O, Bange, G, Bibi, E. | | Deposit date: | 2018-02-12 | | Release date: | 2018-05-09 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.65 Å) | | Cite: | Co-translational Folding Intermediate Dictates Membrane Targeting of the Signal Recognition Particle Receptor.
J. Mol. Biol., 430, 2018
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5GAD
 | | RNC-SRP-SR complex early state | | Descriptor: | 1A9L SS, 23S rRNA, 50S ribosomal protein L10, ... | | Authors: | Jomaa, A, Boehringer, D, Leibundgut, M, Ban, N. | | Deposit date: | 2015-11-24 | | Release date: | 2016-01-27 | | Last modified: | 2019-12-11 | | Method: | ELECTRON MICROSCOPY (3.7 Å) | | Cite: | Structures of the E. coli translating ribosome with SRP and its receptor and with the translocon.
Nat Commun, 7, 2016
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2XXA
 | | The Crystal Structure of the Signal Recognition Particle (SRP) in Complex with its Receptor(SR) | | Descriptor: | 4.5S RNA, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER, ... | | Authors: | Ataide, S.F, Schmitz, N, Shen, K, Ke, A, Shan, S, Doudna, J.A, Ban, N. | | Deposit date: | 2010-11-09 | | Release date: | 2011-03-02 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (3.94 Å) | | Cite: | The Crystal Structure of the Signal Recognition Particle in Complex with its Receptor.
Science, 331, 2011
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5NCO
 | | Quaternary complex between SRP, SR, and SecYEG bound to the translating ribosome | | Descriptor: | 23S rRNA, 4.5S SRP RNA (Ffs), 50S ribosomal protein L10, ... | | Authors: | Jomaa, A, Hwang Fu, Y, Boerhinger, D, Leibundgut, M, Shan, S.O, Ban, N. | | Deposit date: | 2017-03-06 | | Release date: | 2017-05-24 | | Last modified: | 2018-03-28 | | Method: | ELECTRON MICROSCOPY (4.8 Å) | | Cite: | Structure of the quaternary complex between SRP, SR, and translocon bound to the translating ribosome.
Nat Commun, 8, 2017
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3ZN8
 | | Structural Basis of Signal Sequence Surveillance and Selection by the SRP-SR Complex | | Descriptor: | 4.5 S RNA, DIPEPTIDYL AMINOPEPTIDASE B, MAGNESIUM ION, ... | | Authors: | von Loeffelholz, O, Knoops, K, Ariosa, A, Zhang, X, Karuppasamy, M, Huard, K, Schoehn, G, Berger, I, Shan, S.O, Schaffitzel, C. | | Deposit date: | 2013-02-13 | | Release date: | 2013-03-06 | | Last modified: | 2024-05-08 | | Method: | ELECTRON MICROSCOPY (12 Å) | | Cite: | Structural Basis of Signal Sequence Surveillance and Selection by the Srp-Sr Complex
Nat.Struct.Mol.Biol., 20, 2013
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