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PDB: 3 results

6CPG
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BU of 6cpg by Molmil
Structure of dephosphorylated Aurora A (122-403) in complex with inhibiting monobody and AT9283 in an inactive conformation
Descriptor: 1-cyclopropyl-3-{3-[5-(morpholin-4-ylmethyl)-1H-benzimidazol-2-yl]-1H-pyrazol-4-yl}urea, Aurora kinase A, Monobody
Authors:Otten, R, Kutter, S, Zorba, A, Padua, R.A.P, Koide, A, Koide, S, Kern, D.
Deposit date:2018-03-13
Release date:2018-06-27
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Dynamics of human protein kinase Aurora A linked to drug selectivity.
Elife, 7, 2018
6CPE
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BU of 6cpe by Molmil
Structure of apo, dephosphorylated Aurora A (122-403) in an active conformation
Descriptor: 1-ETHOXY-2-(2-ETHOXYETHOXY)ETHANE, Aurora kinase A
Authors:Otten, R, Kutter, S, Buosi, V, Padua, R.A.P, Kern, D.
Deposit date:2018-03-13
Release date:2018-06-27
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Dynamics of human protein kinase Aurora A linked to drug selectivity.
Elife, 7, 2018
6CPF
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BU of 6cpf by Molmil
Structure of dephosphorylated Aurora A (122-403) bound to AMPPCP in an active conformation
Descriptor: Aurora kinase A, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER
Authors:Otten, R, Zorba, A, Padua, R.A.P, Kern, D.
Deposit date:2018-03-13
Release date:2018-06-27
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Dynamics of human protein kinase Aurora A linked to drug selectivity.
Elife, 7, 2018

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