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PDB: 2 results

5XDK
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BU of 5xdk by Molmil
Crystal structure of EGFR 696-1022 T790M in complex with CO-1686
Descriptor: Epidermal growth factor receptor, N-[3-[[2-[[4-(4-ethanoylpiperazin-1-yl)-2-methoxy-phenyl]amino]-5-(trifluoromethyl)pyrimidin-4-yl]amino]phenyl]prop-2-enamide
Authors:Yan, X.E, Yun, C.H.
Deposit date:2017-03-28
Release date:2017-12-13
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.346 Å)
Cite:Structural basis of mutant-selectivity and drug-resistance related to CO-1686.
Oncotarget, 8, 2017
5XDL
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BU of 5xdl by Molmil
Crystal structure of EGFR 696-1022 L858R in complex with CO-1686
Descriptor: Epidermal growth factor receptor, N-[3-[[2-[[4-(4-ethanoylpiperazin-1-yl)-2-methoxy-phenyl]amino]-5-(trifluoromethyl)pyrimidin-4-yl]amino]phenyl]prop-2-enamide
Authors:Yan, X.E, Zhu, S.J, Yun, C.H.
Deposit date:2017-03-28
Release date:2017-12-13
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural basis of mutant-selectivity and drug-resistance related to CO-1686.
Oncotarget, 8, 2017

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