PDB Search results for query - Protein Data Bank Japan

PDB: 2 results

Structure of nsp14 N7-MethylTransferase domain fused with TELSAM bound to SGC8158
Descriptor:	5'-S-(4-{[(4'-chloro[1,1'-biphenyl]-3-yl)methyl]amino}butyl)-5'-thioadenosine, ETHANOL, POTASSIUM ION, ...
Authors:	Kottur, J, Aggarwal, A.K.
Deposit date:	2023-01-07
Release date:	2023-07-26
Last modified:	2023-09-27
Method:	X-RAY DIFFRACTION (1.61 Å)
Cite:	Structures of SARS-CoV-2 N7-methyltransferase with DOT1L and PRMT7 inhibitors provide a platform for new antivirals. Plos Pathog., 19, 2023

Structure of nsp14 N7-MethylTransferase domain fused with TELSAM bound to SGC0946
Descriptor:	5-bromo-7-{5-[(3-{[(4-tert-butylphenyl)carbamoyl]amino}propyl)(propan-2-yl)amino]-5-deoxy-beta-D-ribofuranosyl}-7H-pyrrolo[2,3-d]pyrimidin-4-amine, Transcription factor ETV6,Guanine-N7 methyltransferase nsp14 chimera, ZINC ION
Authors:	Kottur, J, Aggarwal, A.K.
Deposit date:	2023-01-07
Release date:	2023-07-26
Last modified:	2023-09-27
Method:	X-RAY DIFFRACTION (1.57 Å)
Cite:	Structures of SARS-CoV-2 N7-methyltransferase with DOT1L and PRMT7 inhibitors provide a platform for new antivirals. Plos Pathog., 19, 2023