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PDB: 3 results

5NTT
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BU of 5ntt by Molmil
Crystal structure of human Mps1 (TTK) C604Y mutant in complex with NMS-P715
Descriptor: 1,2-ETHANEDIOL, Dual specificity protein kinase TTK, N-(2,6-DIETHYLPHENYL)-1-METHYL-8-({4-[(1-METHYLPIPERIDIN-4-YL)CARBAMOYL]-2-(TRIFLUOROMETHOXY)PHENYL}AMINO)-4,5-DIHYDRO-1H-PYRAZOLO[4,3-H]QUINAZOLINE-3-CARBOXAMIDE
Authors:Hiruma, Y, Joosten, R.P, Perrakis, A.
Deposit date:2017-04-28
Release date:2017-07-26
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Understanding inhibitor resistance in Mps1 kinase through novel biophysical assays and structures.
J. Biol. Chem., 292, 2017
5O91
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BU of 5o91 by Molmil
Crystal structure of human Mps1 (TTK) C604W mutant in complex with Cpd-5
Descriptor: 1,2-ETHANEDIOL, Dual specificity protein kinase TTK, ~{N}-(2,6-diethylphenyl)-8-[[2-methoxy-4-(4-methylpiperazin-1-yl)phenyl]amino]-1-methyl-4,5-dihydropyrazolo[4,3-h]quinazoline-3-carboxamide
Authors:Hiruma, Y, Joosten, R.P, Perrakis, A.
Deposit date:2017-06-15
Release date:2017-07-26
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Understanding inhibitor resistance in Mps1 kinase through novel biophysical assays and structures.
J. Biol. Chem., 292, 2017
5MRB
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BU of 5mrb by Molmil
Crystal structure of human Mps1 (TTK) in complex with Cpd-5
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, Dual specificity protein kinase TTK, ...
Authors:Hiruma, Y, Joosten, R.P, Perrakis, A.
Deposit date:2016-12-22
Release date:2017-07-26
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Understanding inhibitor resistance in Mps1 kinase through novel biophysical assays and structures.
J. Biol. Chem., 292, 2017

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