PDB Search results for query - Protein Data Bank Japan

PDB: 3 results

Structure of the Ancestral Glucocorticoid Receptor 2 ligand binding domain in complex with Prednisolone and PGC1a coregulator fragment
Descriptor:	GLYCEROL, Glucocorticoid Receptor, Peroxisome proliferator-activated receptor gamma coactivator 1-alpha, ...
Authors:	Liu, X, Ortlund, E.A.
Deposit date:	2020-03-23
Release date:	2020-11-04
Last modified:	2023-10-18
Method:	X-RAY DIFFRACTION (1.6 Å)
Cite:	Disruption of a key ligand-H-bond network drives dissociative properties in vamorolone for Duchenne muscular dystrophy treatment. Proc.Natl.Acad.Sci.USA, 117, 2020

Structure of the Ancestral Glucocorticoid Receptor 2 ligand binding domain in complex with vamorolone and SHP coregulator fragment
Descriptor:	GLYCEROL, Glucocorticoid Receptor, Nuclear receptor subfamily 0 group B member 2, ...
Authors:	Liu, X, Ortlund, E.A.
Deposit date:	2020-03-23
Release date:	2020-11-04
Last modified:	2023-10-18
Method:	X-RAY DIFFRACTION (1.59 Å)
Cite:	Disruption of a key ligand-H-bond network drives dissociative properties in vamorolone for Duchenne muscular dystrophy treatment. Proc.Natl.Acad.Sci.USA, 117, 2020

Structure of the Ancestral Glucocorticoid Receptor 2 ligand binding domain in complex with deacetylated deflazacort and PGC1a coregulator fragment
Descriptor:	(4aR,4bS,5S,6aS,6bS,9aR,10aS,10bS)-5-hydroxy-6b-(hydroxyacetyl)-4a,6a,8-trimethyl-4a,4b,5,6,6a,6b,9a,10,10a,10b,11,12-dodecahydro-2H-naphtho[2',1':4,5]indeno[1,2-d][1,3]oxazol-2-one, GLYCEROL, Glucocorticoid Receptor, ...
Authors:	Liu, X, Ortlund, E.A.
Deposit date:	2020-03-23
Release date:	2020-11-04
Last modified:	2023-10-18
Method:	X-RAY DIFFRACTION (1.45 Å)
Cite:	Disruption of a key ligand-H-bond network drives dissociative properties in vamorolone for Duchenne muscular dystrophy treatment. Proc.Natl.Acad.Sci.USA, 117, 2020