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PDB: 9 results

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BU of 6bcx by Molmil

mTORC1 structure refined to 3.0 angstroms
Descriptor:	ADENOSINE-5'-TRIPHOSPHATE, Eukaryotic translation initiation factor 4E-binding protein 1, MAGNESIUM ION, ...
Authors:	Pavletich, N.P, Yang, H.
Deposit date:	2017-10-20
Release date:	2017-12-20
Last modified:	2024-03-13
Method:	ELECTRON MICROSCOPY (3.23 Å)
Cite:	Mechanisms of mTORC1 activation by RHEB and inhibition by PRAS40. Nature, 552, 2017

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BU of 6bcu by Molmil

Cryo-EM structure of the activated RHEB-mTORC1 refined to 3.4 angstrom
Descriptor:	ADENOSINE-5'-TRIPHOSPHATE, Eukaryotic translation initiation factor 4E-binding protein 1, GTP-binding protein Rheb, ...
Authors:	Pavletich, N.P, Yang, H.
Deposit date:	2017-10-20
Release date:	2017-12-20
Last modified:	2024-03-13
Method:	ELECTRON MICROSCOPY (3.8 Å)
Cite:	Mechanisms of mTORC1 activation by RHEB and inhibition by PRAS40. Nature, 552, 2017

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BU of 5wbl by Molmil

Crystal structure of the Arabidopsis thaliana Raptor in complex with the TOS peptide of human PRAS40
Descriptor:	Proline-rich AKT1 substrate 1, Regulatory-associated protein of TOR 1
Authors:	Pavletich, N.P, Jiang, X.
Deposit date:	2017-06-29
Release date:	2017-12-20
Last modified:	2023-10-04
Method:	X-RAY DIFFRACTION (3.35 Å)
Cite:	Mechanisms of mTORC1 activation by RHEB and inhibition by PRAS40. Nature, 552, 2017

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BU of 5wbh by Molmil

Structure of the FRB domain of mTOR bound to a substrate recruitment peptide of S6K1
Descriptor:	Ribosomal protein S6 kinase beta-1, Serine/threonine-protein kinase mTOR
Authors:	Pavletich, N.P, Yang, H.
Deposit date:	2017-06-29
Release date:	2017-12-20
Last modified:	2023-10-04
Method:	X-RAY DIFFRACTION (1.75 Å)
Cite:	Mechanisms of mTORC1 activation by RHEB and inhibition by PRAS40. Nature, 552, 2017

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BU of 5wbk by Molmil

Crystal structure of the arabidopsis thaliana Raptor in complex with the TOS peptide of human S6K1
Descriptor:	Regulatory-associated protein of TOR 1, Ribosomal protein S6 kinase beta-1
Authors:	Pavletich, N.P, Jiang, X.
Deposit date:	2017-06-29
Release date:	2017-12-20
Last modified:	2023-10-04
Method:	X-RAY DIFFRACTION (3.11 Å)
Cite:	Mechanisms of mTORC1 activation by RHEB and inhibition by PRAS40. Nature, 552, 2017

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BU of 5wbi by Molmil

Crystal structure of the Arabidopsis thaliana Raptor
Descriptor:	Regulatory-associated protein of TOR 1
Authors:	Pavletich, N.P, Jiang, X.
Deposit date:	2017-06-29
Release date:	2017-12-20
Last modified:	2024-03-13
Method:	X-RAY DIFFRACTION (3 Å)
Cite:	Mechanisms of mTORC1 activation by RHEB and inhibition by PRAS40. Nature, 552, 2017

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BU of 5wbu by Molmil

Crystal structure of mTOR(deltaN)-mLST8-PRAS40(alpha-helix & beta-strand) complex
Descriptor:	Proline-rich AKT1 substrate 1, Serine/threonine-protein kinase mTOR, Target of rapamycin complex subunit LST8
Authors:	Pavletich, N.P, Yang, H.
Deposit date:	2017-06-29
Release date:	2017-12-20
Last modified:	2023-10-04
Method:	X-RAY DIFFRACTION (3.42 Å)
Cite:	Mechanisms of mTORC1 activation by RHEB and inhibition by PRAS40. Nature, 552, 2017

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BU of 5wbj by Molmil

Crystal structure of the arabidopsis thaliana Raptor in complex with the TOS peptide of human 4EBP1
Descriptor:	Eukaryotic translation initiation factor 4E-binding protein 1, Regulatory-associated protein of TOR 1
Authors:	Pavletich, N.P, Jiang, X.
Deposit date:	2017-06-29
Release date:	2017-12-20
Last modified:	2023-10-04
Method:	X-RAY DIFFRACTION (3 Å)
Cite:	Mechanisms of mTORC1 activation by RHEB and inhibition by PRAS40. Nature, 552, 2017

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BU of 5wby by Molmil

Crystal structure of mTOR(deltaN)-mLST8-PRAS40(beta-strand) complex
Descriptor:	Proline-rich AKT1 substrate 1, Serine/threonine-protein kinase mTOR, Target of rapamycin complex subunit LST8
Authors:	Pavletich, N.P, Yang, H.
Deposit date:	2017-06-29
Release date:	2017-12-20
Last modified:	2023-10-04
Method:	X-RAY DIFFRACTION (3.1 Å)
Cite:	Mechanisms of mTORC1 activation by RHEB and inhibition by PRAS40. Nature, 552, 2017

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