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PDB: 5 results
8U4U
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BU of 8u4u by Molmil
Crystal structure of 53BP1 tandem Tudor domain homodimer engineered with two disulfide bridges
Descriptor: TP53-binding protein 1
Authors:Cui, G, Botuyan, M.V, Thompson, J.R, Mer, G.
Deposit date:2023-09-11
Release date:2023-09-20
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.79 Å)
Cite:An autoinhibited state of 53BP1 revealed by small molecule antagonists and protein engineering.
Nat Commun, 14, 2023
6MXY
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BU of 6mxy by Molmil
Structure of 53BP1 tandem Tudor domains in complex with small molecule UNC3351
Descriptor: N-[3-(tert-butylamino)propyl]-3-(trifluoromethyl)benzamide, PHOSPHATE ION, TP53-binding protein 1
Authors:Cui, G, Botuyan, M.V, Mer, G.
Deposit date:2018-10-31
Release date:2019-11-27
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.624 Å)
Cite:An autoinhibited state of 53BP1 revealed by small molecule antagonists and protein engineering.
Nat Commun, 14, 2023
6MXZ
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BU of 6mxz by Molmil
Structure of 53BP1 Tudor domains in complex with small molecule UNC3474
Descriptor: FORMIC ACID, N-[3-(tert-butylamino)propyl]-3-(propan-2-yl)benzamide, TP53-binding protein 1
Authors:Cui, G, Botuyan, M.V, Schuller, D.J, Mer, G.
Deposit date:2018-10-31
Release date:2019-11-27
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:An autoinhibited state of 53BP1 revealed by small molecule antagonists and protein engineering.
Nat Commun, 14, 2023
6MY0
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BU of 6my0 by Molmil
Structure of 53BP1 Tandem Tudor domains with E1549P and D1550N mutations
Descriptor: TP53-binding protein 1
Authors:Cui, G, Botuyan, M.V, Mer, G.
Deposit date:2018-10-31
Release date:2019-11-27
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:An autoinhibited state of 53BP1 revealed by small molecule antagonists and protein engineering.
Nat Commun, 14, 2023
6MXX
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BU of 6mxx by Molmil
Structure of 53BP1 tandem Tudor domains in complex with small molecule UNC2991
Descriptor: FORMIC ACID, N-[3-(tert-butylamino)propyl]-3-iodobenzamide, PHOSPHATE ION, ...
Authors:Cui, G, Botuyan, M.V, Mer, G.
Deposit date:2018-10-31
Release date:2019-11-27
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.298 Å)
Cite:An autoinhibited state of 53BP1 revealed by small molecule antagonists and protein engineering.
Nat Commun, 14, 2023

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