8ZWG
 
 | | cryoEM structure of JR14a bound C3aR-Gi complex | | Descriptor: | (2~{S})-5-[bis(azanyl)methylideneamino]-2-[[5-[bis(4-chlorophenyl)methyl]-3-methyl-thiophen-2-yl]carbonylamino]pentanoic acid, Beta-2 adrenergic receptor,C3a anaphylatoxin chemotactic receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | Authors: | Luo, P, Xu, Y, Xu, H.E. | | Deposit date: | 2024-06-13 | | Release date: | 2025-05-14 | | Method: | ELECTRON MICROSCOPY (2.87 Å) | | Cite: | Structural insights into the agonist activity of the nonpeptide modulator JR14a on C3aR.
Cell Discov, 11, 2025
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8ZWF
 | | cryoEM structure of JR14a bound C3aR-BRIL-BAG2 complex | | Descriptor: | (2~{S})-5-[bis(azanyl)methylideneamino]-2-[[5-[bis(4-chlorophenyl)methyl]-3-methyl-thiophen-2-yl]carbonylamino]pentanoic acid, Beta-2 adrenergic receptor,C3a anaphylatoxin chemotactic receptor,Soluble cytochrome b562, anti-BRIL Fab HC, ... | | Authors: | Luo, P, Xu, Y, Xu, H.E. | | Deposit date: | 2024-06-13 | | Release date: | 2025-05-14 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | Structural insights into the agonist activity of the nonpeptide modulator JR14a on C3aR.
Cell Discov, 11, 2025
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