8WWK
 
 | | MCH-MCHR1-Gi complex, T1 state | | Descriptor: | Antibody fragment ScFv16, Fusion protein 1,Melanin-concentrating hormone receptor 1,Fusion protein 2, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | Authors: | Gong, W, Ye, X, Liu, G. | | Deposit date: | 2023-10-25 | | Release date: | 2024-11-13 | | Last modified: | 2024-12-18 | | Method: | ELECTRON MICROSCOPY (2.61 Å) | | Cite: | Structural insights into physiological activation and antagonism of melanin-concentrating hormone receptor MCHR1.
Cell Discov, 10, 2024
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8WWM
 | | MCH-MCHR1-Gi complex, L2 state | | Descriptor: | Antibody fragment ScFv16, Fusion protein 1,Melanin-concentrating hormone receptor 1,Fusion protein 2, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | Authors: | Gong, W, Ye, X, Liu, G. | | Deposit date: | 2023-10-25 | | Release date: | 2024-11-13 | | Last modified: | 2024-12-18 | | Method: | ELECTRON MICROSCOPY (2.81 Å) | | Cite: | Structural insights into physiological activation and antagonism of melanin-concentrating hormone receptor MCHR1.
Cell Discov, 10, 2024
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8WWL
 | | MCH-MCHR1-Gi complex, T2 state | | Descriptor: | Antibody fragment ScFv16, Fusion protein 1,Melanin-concentrating hormone receptor 1,Fusion protein 2, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | Authors: | Gong, W, Ye, X, Liu, G. | | Deposit date: | 2023-10-25 | | Release date: | 2024-11-13 | | Last modified: | 2024-12-18 | | Method: | ELECTRON MICROSCOPY (2.78 Å) | | Cite: | Structural insights into physiological activation and antagonism of melanin-concentrating hormone receptor MCHR1.
Cell Discov, 10, 2024
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8WWN
 | | MCH-MCHR1-Gi complex,L1 state | | Descriptor: | Antibody fragment ScFv16, Fusion protein 1,Melanin-concentrating hormone receptor 1,Fusion protein 2, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | Authors: | Gong, W, Ye, X, Liu, G. | | Deposit date: | 2023-10-25 | | Release date: | 2024-11-13 | | Last modified: | 2024-12-18 | | Method: | ELECTRON MICROSCOPY (2.65 Å) | | Cite: | Structural insights into physiological activation and antagonism of melanin-concentrating hormone receptor MCHR1.
Cell Discov, 10, 2024
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8YNS
 | | Cryo-EM structure of SNAP-94847-bound MCHR1, S1 state | | Descriptor: | Antibody 1B3 Fab heavy chain, Antibody 1B3 Fab light chain, Glue molecule 4-9, ... | | Authors: | Ye, X, Liu, G, Li, X, Liu, H, Gong, W. | | Deposit date: | 2024-03-11 | | Release date: | 2024-12-18 | | Last modified: | 2025-01-08 | | Method: | ELECTRON MICROSCOPY (3.33 Å) | | Cite: | Structural insights into physiological activation and antagonism of melanin-concentrating hormone receptor MCHR1.
Cell Discov, 10, 2024
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8YNT
 | | Cryo-EM structure of SNAP-94847-bound MCHR1, S2 state | | Descriptor: | Antibody 1B3 Fab heavy chain, Antibody 1B3 Fab light chain, Glue molecule 4-9, ... | | Authors: | Ye, X, Liu, G, Li, X, Liu, H, Gong, W. | | Deposit date: | 2024-03-11 | | Release date: | 2024-12-18 | | Last modified: | 2025-01-08 | | Method: | ELECTRON MICROSCOPY (3.43 Å) | | Cite: | Structural insights into physiological activation and antagonism of melanin-concentrating hormone receptor MCHR1.
Cell Discov, 10, 2024
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