8YNT

Cryo-EM structure of SNAP-94847-bound MCHR1, S2 state

This is a non-PDB format compatible entry.

Summary for 8YNT

• Entry DOI: 10.2210/pdb8ynt/pdb
• EMDB information: 39430
• Descriptor: Antibody 1B3 Fab heavy chain, Antibody 1B3 Fab light chain, Glue molecule 4-9, ... (5 entities in total)
• Functional Keywords: gpcr, signaling protein
• Biological source: synthetic construct; More
• Total number of polymer chains: 4
• Total formula weight: 145381.99

Authors

Ye, X.,Liu, G.,Li, X.,Liu, H.,Gong, W. (deposition date: 2024-03-11, release date: 2024-12-18, Last modification date: 2025-01-08)

• Primary citation: Ye, X.,Liu, G.,Li, X.,He, B.,Tao, Y.,Guan, J.,Mu, Y.,Liu, H.,Gong, W.; Structural insights into physiological activation and antagonism of melanin-concentrating hormone receptor MCHR1.; Cell Discov, 10:124-124, 2024; PubMed: 39616153; DOI: 10.1038/s41421-024-00754-0

Experimental method

ELECTRON MICROSCOPY (3.43 Å)