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PDB: 3 results

5OEG
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BU of 5oeg by Molmil
Molecular tweezers modulate 14-3-3 protein-protein interactions
Descriptor: (1R,5S,9S,16R,20R,24S,28S,35R)-3,22-Bis(dihydroxyphosphoryloxy)tridecacyclo[22.14.1.15,20.19,16.128,35.02,23.04,21.06,19.08,17.010,15.025,38.027,36.029,34]dotetraconta-2(23),3,6,8(17),10,12,14,18,21,25,27(36),29,31,33,37-pentadecaene, 14-3-3 protein sigma, CHLORIDE ION
Authors:Bier, D, Ottmann, C.
Deposit date:2017-07-07
Release date:2017-07-26
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:Molecular tweezers modulate 14-3-3 protein-protein interactions.
Nat Chem, 5, 2013
5OEH
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BU of 5oeh by Molmil
Molecular tweezers modulate 14-3-3 protein-protein interactions.
Descriptor: (1R,5S,9S,16R,20R,24S,28S,35R)-3,22-Bis(dihydroxyphosphoryloxy)tridecacyclo[22.14.1.15,20.19,16.128,35.02,23.04,21.06,19.08,17.010,15.025,38.027,36.029,34]dotetraconta-2(23),3,6,8(17),10,12,14,18,21,25,27(36),29,31,33,37-pentadecaene, 14-3-3 protein sigma, CHLORIDE ION, ...
Authors:Bier, D, Ottmann, C.
Deposit date:2017-07-07
Release date:2017-07-26
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Molecular tweezers modulate 14-3-3 protein-protein interactions.
Nat Chem, 5, 2013
6Y7T
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BU of 6y7t by Molmil
Engineered conjugation of lysine-specific molecular tweezers with ExoS derived peptidic inhibitor enhance affinity towards target protein 14-3-3 through ditopic binding
Descriptor: 14-3-3 protein sigma, ExoSTWZ molecular tweezer, Exoenzyme S, ...
Authors:Guillory, X, Ottmann, C.
Deposit date:2020-03-02
Release date:2021-03-31
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Supramolecular Enhancement of a Natural 14-3-3 Protein Ligand.
J.Am.Chem.Soc., 143, 2021

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