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PDB: 12 results
5CLB
Alkylpurine DNA glycosylase AlkD bound to DNA containing a 3-methyladenine analog (9-mer A)
Descriptor:
AlkD, DNA (5'-D(*AP*AP*GP*CP*AP*(DZM)P*AP*CP*C)-3'), DNA (5'-D(*TP*GP*GP*TP*TP*TP*GP*CP*T)-3')
Authors:
Mullins, E.A
,
Eichman, B.F.
Deposit date:
2015-07-16
Release date:
2015-10-28
Last modified:
2023-09-27
Method:
X-RAY DIFFRACTION (1.766 Å)
Cite:
The DNA glycosylase AlkD uses a non-base-flipping mechanism to excise bulky lesions.
Nature, 527, 2015
5CL3
Alkylpurine DNA glycosylase AlkD bound to DNA containing a 3-methyladenine analog (100% substrate at 4 hours)
Descriptor:
AlkD, DNA (5'-D(*CP*CP*CP*GP*AP*(DZM)P*AP*GP*TP*CP*CP*G)-3'), DNA (5'-D(*CP*GP*GP*AP*CP*TP*TP*TP*CP*GP*GP*G)-3')
Authors:
Mullins, E.A
,
Eichman, B.F.
Deposit date:
2015-07-16
Release date:
2015-10-28
Last modified:
2023-09-27
Method:
X-RAY DIFFRACTION (1.971 Å)
Cite:
The DNA glycosylase AlkD uses a non-base-flipping mechanism to excise bulky lesions.
Nature, 527, 2015
5CL8
Alkylpurine DNA glycosylase AlkD bound to DNA containing an abasic site and a free nucleobase (100% product at 144 hours)
Descriptor:
7-methyl-3H-imidazo[4,5-c]pyridin-4-amine, AlkD, DNA (5'-D(*CP*CP*CP*GP*AP*(ORP)P*AP*GP*TP*CP*CP*G)-3'), ...
Authors:
Mullins, E.A
,
Eichman, B.F.
Deposit date:
2015-07-16
Release date:
2015-10-28
Last modified:
2023-09-27
Method:
X-RAY DIFFRACTION (1.38 Å)
Cite:
The DNA glycosylase AlkD uses a non-base-flipping mechanism to excise bulky lesions.
Nature, 527, 2015
5CLE
Alkylpurine DNA glycosylase AlkD bound to DNA containing an abasic-site analog and a free 3-methyladenine nucleobase
Descriptor:
3-METHYL-3H-PURIN-6-YLAMINE, AlkD, DNA (5'-D(*CP*CP*CP*GP*AP*(3DR)P*AP*GP*TP*CP*CP*G)-3'), ...
Authors:
Mullins, E.A
,
Eichman, B.F.
Deposit date:
2015-07-16
Release date:
2015-10-28
Last modified:
2023-09-27
Method:
X-RAY DIFFRACTION (1.73 Å)
Cite:
The DNA glycosylase AlkD uses a non-base-flipping mechanism to excise bulky lesions.
Nature, 527, 2015
5CL9
Alkylpurine DNA glycosylase AlkD bound to DNA containing an abasic site and a free nucleobase (100% product at 240 hours)
Descriptor:
7-methyl-3H-imidazo[4,5-c]pyridin-4-amine, AlkD, DNA (5'-D(*CP*CP*CP*GP*AP*(ORP)P*AP*GP*TP*CP*CP*G)-3'), ...
Authors:
Mullins, E.A
,
Eichman, B.F.
Deposit date:
2015-07-16
Release date:
2015-10-28
Last modified:
2023-09-27
Method:
X-RAY DIFFRACTION (1.538 Å)
Cite:
The DNA glycosylase AlkD uses a non-base-flipping mechanism to excise bulky lesions.
Nature, 527, 2015
5CL4
Alkylpurine DNA glycosylase AlkD bound to DNA containing a 3-methyladenine analog or DNA containing an abasic site and a free nucleobase (71% substrate/29% product at 24 hours)
Descriptor:
7-methyl-3H-imidazo[4,5-c]pyridin-4-amine, AlkD, DNA (5'-D(*CP*CP*CP*GP*AP*(DZM)P*AP*GP*TP*CP*CP*G)-3'), ...
Authors:
Mullins, E.A
,
Eichman, B.F.
Deposit date:
2015-07-16
Release date:
2015-10-28
Last modified:
2023-09-27
Method:
X-RAY DIFFRACTION (1.866 Å)
Cite:
The DNA glycosylase AlkD uses a non-base-flipping mechanism to excise bulky lesions.
Nature, 527, 2015
5CL7
Alkylpurine DNA glycosylase AlkD bound to DNA containing a 3-methyladenine analog or DNA containing an abasic site and a free nucleobase (18% substrate/82% product at 96 hours)
Descriptor:
7-methyl-3H-imidazo[4,5-c]pyridin-4-amine, AlkD, DNA (5'-D(*CP*CP*CP*GP*AP*(DZM)P*AP*GP*TP*CP*CP*G)-3'), ...
Authors:
Mullins, E.A
,
Eichman, B.F.
Deposit date:
2015-07-16
Release date:
2015-10-28
Last modified:
2023-09-27
Method:
X-RAY DIFFRACTION (1.44 Å)
Cite:
The DNA glycosylase AlkD uses a non-base-flipping mechanism to excise bulky lesions.
Nature, 527, 2015
5CLA
Alkylpurine DNA glycosylase AlkD bound to DNA containing an abasic site and a free nucleobase (100% product at 360 hours)
Descriptor:
7-methyl-3H-imidazo[4,5-c]pyridin-4-amine, AlkD, DNA (5'-D(*CP*CP*CP*GP*AP*(ORP)P*AP*GP*TP*CP*CP*G)-3'), ...
Authors:
Mullins, E.A
,
Eichman, B.F.
Deposit date:
2015-07-16
Release date:
2015-10-28
Last modified:
2023-09-27
Method:
X-RAY DIFFRACTION (1.541 Å)
Cite:
The DNA glycosylase AlkD uses a non-base-flipping mechanism to excise bulky lesions.
Nature, 527, 2015
5CLD
Alkylpurine DNA glycosylase AlkD bound to DNA containing an oxocarbenium-intermediate analog and a free 3-methyladenine nucleobase
Descriptor:
3-METHYL-3H-PURIN-6-YLAMINE, AlkD, DNA (5'-D(*CP*CP*CP*GP*AP*(NRI)P*AP*GP*TP*CP*CP*G)-3'), ...
Authors:
Mullins, E.A
,
Eichman, B.F.
Deposit date:
2015-07-16
Release date:
2015-10-28
Last modified:
2023-09-27
Method:
X-RAY DIFFRACTION (1.541 Å)
Cite:
The DNA glycosylase AlkD uses a non-base-flipping mechanism to excise bulky lesions.
Nature, 527, 2015
5CL5
Alkylpurine DNA glycosylase AlkD bound to DNA containing a 3-methyladenine analog or DNA containing an abasic site and a free nucleobase (51% substrate/49% product at 48 hours)
Descriptor:
7-methyl-3H-imidazo[4,5-c]pyridin-4-amine, AlkD, DNA (5'-D(*CP*CP*CP*GP*AP*(DZM)P*AP*GP*TP*CP*CP*G)-3'), ...
Authors:
Mullins, E.A
,
Eichman, B.F.
Deposit date:
2015-07-16
Release date:
2015-10-28
Last modified:
2023-09-27
Method:
X-RAY DIFFRACTION (1.569 Å)
Cite:
The DNA glycosylase AlkD uses a non-base-flipping mechanism to excise bulky lesions.
Nature, 527, 2015
5CLC
Alkylpurine DNA glycosylase AlkD bound to DNA containing a 3-methyladenine analog (9-mer B)
Descriptor:
AlkD, DNA (5'-D(*AP*AP*GP*CP*CP*(DZM)P*CP*CP*C)-3'), DNA (5'-D(*TP*GP*GP*GP*TP*GP*GP*CP*T)-3')
Authors:
Mullins, E.A
,
Eichman, B.F.
Deposit date:
2015-07-16
Release date:
2015-10-28
Last modified:
2023-09-27
Method:
X-RAY DIFFRACTION (1.729 Å)
Cite:
The DNA glycosylase AlkD uses a non-base-flipping mechanism to excise bulky lesions.
Nature, 527, 2015
5CL6
Alkylpurine DNA glycosylase AlkD bound to DNA containing a 3-methyladenine analog or DNA containing an abasic site and a free nucleobase (33% substrate/67% product at 72 hours)
Descriptor:
7-methyl-3H-imidazo[4,5-c]pyridin-4-amine, AlkD, DNA (5'-D(*CP*CP*CP*GP*AP*(DZM)P*AP*GP*TP*CP*CP*G)-3'), ...
Authors:
Mullins, E.A
,
Eichman, B.F.
Deposit date:
2015-07-16
Release date:
2015-10-28
Last modified:
2023-09-27
Method:
X-RAY DIFFRACTION (1.541 Å)
Cite:
The DNA glycosylase AlkD uses a non-base-flipping mechanism to excise bulky lesions.
Nature, 527, 2015
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PDB entries from 2024-09-11