PDB Search results for query - Protein Data Bank Japan

PDB: 2 results

Crystal structure of human-yeast chimera acetyl coA carboxylase CT domain bound to Compound 6
Descriptor:	1'-(2H-indazol-5-ylcarbonyl)-1-(propan-2-yl)-1,4-dihydrospiro[indazole-5,4'-piperidin]-7(6H)-one, Acetyl-CoA carboxylase
Authors:	Vajdos, F.F.
Deposit date:	2014-11-18
Release date:	2014-12-10
Last modified:	2024-02-28
Method:	X-RAY DIFFRACTION (2.23 Å)
Cite:	Decreasing the Rate of Metabolic Ketone Reduction in the Discovery of a Clinical Acetyl-CoA Carboxylase Inhibitor for the Treatment of Diabetes. J.Med.Chem., 57, 2014

Crystal structure of human-yeast chimera acetyl coA carboxylase CT domain bound to Compound 1
Descriptor:	2'-tert-butyl-1-(2H-indazol-5-ylcarbonyl)-2'H-spiro[piperidine-4,5'-pyrano[3,2-c]pyrazol]-7'(6'H)-one, Acetyl-CoA carboxylase
Authors:	Vajdos, F.F.
Deposit date:	2014-11-17
Release date:	2015-01-14
Last modified:	2024-02-28
Method:	X-RAY DIFFRACTION (2.89 Å)
Cite:	Decreasing the Rate of Metabolic Ketone Reduction in the Discovery of a Clinical Acetyl-CoA Carboxylase Inhibitor for the Treatment of Diabetes. J.Med.Chem., 57, 2014