PDB Search results for query - Protein Data Bank Japan

PDB: 2 results

Aurora A kinase domain with compound 2 (N-[1-(3-cyanobenzyl)-1H-pyrazol-4-yl]-6-(1H-pyrazol-4-yl)-1H-indazole-3-carboxamide)
Descriptor:	Aurora kinase A, N-[1-(3-cyanobenzyl)-1H-pyrazol-4-yl]-6-(1H-pyrazol-4-yl)-1H-indazole-3-carboxamide
Authors:	Ultsch, M, Eigenbrot, C.
Deposit date:	2014-03-05
Release date:	2014-07-02
Last modified:	2023-09-20
Method:	X-RAY DIFFRACTION (2.8 Å)
Cite:	Property- and structure-guided discovery of a tetrahydroindazole series of interleukin-2 inducible T-cell kinase inhibitors. J.Med.Chem., 57, 2014

ITK kinase domain with compound GNE-9822
Descriptor:	1-ETHOXY-2-(2-ETHOXYETHOXY)ETHANE, N-{1-[(1S)-3-(dimethylamino)-1-phenylpropyl]-1H-pyrazol-4-yl}-6,6-dimethyl-4,5,6,7-tetrahydro-1H-indazole-3-carboxamide, Tyrosine-protein kinase ITK/TSK
Authors:	McEwan, P.A, Barker, J.J, Eigenbrot, C.
Deposit date:	2014-03-03
Release date:	2014-07-02
Last modified:	2023-09-20
Method:	X-RAY DIFFRACTION (1.71 Å)
Cite:	Property- and structure-guided discovery of a tetrahydroindazole series of interleukin-2 inducible T-cell kinase inhibitors. J.Med.Chem., 57, 2014