PDB Search results for query - Protein Data Bank Japan

PDB: 3 results

Crystal structure of spleen tyrosine kinase complexed with [6-((S)-2-Methyl-pyrrolidin-1-yl)-pyridin-2-yl]-(6-phenyl-imidazo[1,2-b]pyridazin-8-yl)-amine
Descriptor:	N-{6-[(2S)-2-methylpyrrolidin-1-yl]pyridin-2-yl}-6-phenylimidazo[1,2-b]pyridazin-8-amine, Tyrosine-protein kinase SYK
Authors:	Kuglstatter, A, Slade, M.
Deposit date:	2012-07-06
Release date:	2013-01-30
Last modified:	2023-09-13
Method:	X-RAY DIFFRACTION (1.85 Å)
Cite:	Rational design of highly selective spleen tyrosine kinase inhibitors. J.Med.Chem., 55, 2012

Crystal structure of spleen tyrosine kinase complexed with 3-(8-{4-[Ethyl-(2-hydroxy-ethyl)-amino]-phenylamino}-imidazo[1,2-a]pyrazin-5-yl)-phenol
Descriptor:	3-[8-({4-[ethyl(2-hydroxyethyl)amino]phenyl}amino)imidazo[1,2-a]pyrazin-5-yl]phenol, Tyrosine-protein kinase SYK
Authors:	Kuglstatter, A, Villasenor, A.G.
Deposit date:	2012-07-05
Release date:	2013-01-30
Last modified:	2023-09-13
Method:	X-RAY DIFFRACTION (2.318 Å)
Cite:	Rational design of highly selective spleen tyrosine kinase inhibitors. J.Med.Chem., 55, 2012

Crystal structure of spleen tyrosine kinase complexed with N-{(S)-1-[7-(3,4-Dimethoxy-phenylamino)-thiazolo[5,4-d]pyrimidin-5-yl]-pyrrolidin-3-yl}-terephthalamic acid
Descriptor:	4-{[(3S)-1-{7-[(3,4-dimethoxyphenyl)amino][1,3]thiazolo[5,4-d]pyrimidin-5-yl}pyrrolidin-3-yl]carbamoyl}benzoic acid, Tyrosine-protein kinase SYK
Authors:	Kuglstatter, A, Slade, M.
Deposit date:	2012-07-05
Release date:	2013-01-30
Last modified:	2023-09-13
Method:	X-RAY DIFFRACTION (1.4 Å)
Cite:	Rational design of highly selective spleen tyrosine kinase inhibitors. J.Med.Chem., 55, 2012