PDB Search results for query - Protein Data Bank Japan

PDB: 3 results

L. CASEI THYMIDYLATE SYNTHASE WITH SPECIES SPECIFIC INHIBITOR
Descriptor:	3'-3"-DICHLOROPHENOL-1,8-3H-BENZO[DE]ISOCHROMEN-1-ONE, PHOSPHATE ION, THYMIDYLATE SYNTHASE
Authors:	Stout, T.J, Stroud, R.M.
Deposit date:	1997-06-12
Release date:	1998-06-17
Last modified:	2024-05-22
Method:	X-RAY DIFFRACTION (2.5 Å)
Cite:	Structure-based design of inhibitors specific for bacterial thymidylate synthase. Biochemistry, 38, 1999

L. CASEI THYMIDYLATE SYNTHASE WITH SPECIES SPECIFIC INHIBITOR
Descriptor:	3-DIPHENOL-6-NITRO-3H-BENZO[DE]ISOCHROMEN-1-ONE, PHOSPHATE ION, THYMIDYLATE SYNTHASE
Authors:	Stout, T.J, Stroud, R.M.
Deposit date:	1997-06-12
Release date:	1998-06-17
Last modified:	2024-05-22
Method:	X-RAY DIFFRACTION (3 Å)
Cite:	Structure-based design of inhibitors specific for bacterial thymidylate synthase. Biochemistry, 38, 1999

Cryptococcus neoformans thymidylate synthase complexed with substrate and an antifolate
Descriptor:	10-PROPARGYL-5,8-DIDEAZAFOLIC ACID, 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, Thymidylate synthase
Authors:	Finer-Moore, J.S, Anderson, A.C, O'Neil, R.H, Costi, M.P, Ferrari, S, Krucinski, J, Stroud, R.M.
Deposit date:	2005-07-14
Release date:	2005-12-06
Last modified:	2018-02-14
Method:	X-RAY DIFFRACTION (2.08 Å)
Cite:	The structure of Cryptococcus neoformans thymidylate synthase suggests strategies for using target dynamics for species-specific inhibition. Acta Crystallogr.,Sect.D, 61, 2005