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PDB: 2 results

4Y30
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BU of 4y30 by Molmil
Crystal structure of human protein arginine methyltransferase PRMT6 bound to SAH and EPZ020411
Descriptor: GLYCEROL, MAGNESIUM ION, N,N'-dimethyl-N-({3-[4-({trans-3-[2-(tetrahydro-2H-pyran-4-yl)ethoxy]cyclobutyl}oxy)phenyl]-1H-pyrazol-4-yl}methyl)ethane-1,2-diamine, ...
Authors:Swinger, K.K, Boriack-Sjodin, P.A.
Deposit date:2015-02-10
Release date:2015-04-22
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Aryl Pyrazoles as Potent Inhibitors of Arginine Methyltransferases: Identification of the First PRMT6 Tool Compound.
Acs Med.Chem.Lett., 6, 2015
4Y2H
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BU of 4y2h by Molmil
Crystal structure of human protein arginine methyltransferase PRMT6 bound to SAH and an aryl pyrazole inhibitor
Descriptor: GLYCEROL, N-{[5-(4-fluorophenyl)-1H-pyrazol-4-yl]methyl}-N-methylethane-1,2-diamine, Protein arginine N-methyltransferase 6, ...
Authors:Swinger, K.K, Boriack-Sjodin, P.A.
Deposit date:2015-02-09
Release date:2015-04-22
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.37 Å)
Cite:Aryl Pyrazoles as Potent Inhibitors of Arginine Methyltransferases: Identification of the First PRMT6 Tool Compound.
Acs Med.Chem.Lett., 6, 2015

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