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PDB: 3 results

4DEI
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BU of 4dei by Molmil
Crystal structure of c-Met in complex with triazolopyridinone inhibitor 24
Descriptor: 3-{(1S)-1-[3-(2-methoxyethoxy)quinolin-6-yl]ethyl}-5-(3-methyl-1,2-thiazol-5-yl)-3,5-dihydro-4H-[1,2,3]triazolo[4,5-c]pyridin-4-one, Hepatocyte growth factor receptor
Authors:Whittington, D.A, Long, A.M.
Deposit date:2012-01-20
Release date:2012-05-30
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Discovery and optimization of a potent and selective triazolopyridinone series of c-Met inhibitors.
Bioorg.Med.Chem.Lett., 22, 2012
4DEG
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BU of 4deg by Molmil
Crystal structure of c-Met in complex with triazolopyridazine inhibitor 2
Descriptor: 7-methoxy-N-{[6-(3-methyl-1,2-thiazol-5-yl)[1,2,4]triazolo[4,3-b]pyridazin-3-yl]methyl}-1,5-naphthyridin-4-amine, Hepatocyte growth factor receptor
Authors:Whittington, D.A, Bellon, S.F, Long, A.M.
Deposit date:2012-01-20
Release date:2012-05-30
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2 Å)
Cite:Discovery and optimization of a potent and selective triazolopyridinone series of c-Met inhibitors.
Bioorg.Med.Chem.Lett., 22, 2012
4DEH
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BU of 4deh by Molmil
Crystal structure of c-Met in complex with triazolopyridinone inhibitor 3
Descriptor: 5-phenyl-3-(quinolin-6-ylmethyl)-3,5,6,7-tetrahydro-4H-[1,2,3]triazolo[4,5-c]pyridin-4-one, Hepatocyte growth factor receptor
Authors:Whittington, D.A, Bellon, S.F, Long, A.M.
Deposit date:2012-01-20
Release date:2012-05-30
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2 Å)
Cite:Discovery and optimization of a potent and selective triazolopyridinone series of c-Met inhibitors.
Bioorg.Med.Chem.Lett., 22, 2012

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