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6IDO
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BU of 6ido by Molmil
Crystal structure of Klebsiella pneumoniae sigma4 of sigmaS fusing with the RNA polymerase beta-flap-tip-helix in complex with -35 element DNA
Descriptor: DNA (5'-D(P*CP*CP*AP*CP*TP*TP*GP*AP*CP*AP*AP*AP*TP*CP*G)-3'), DNA (5'-D(P*GP*AP*TP*TP*TP*GP*TP*CP*AP*AP*GP*TP*GP*GP*C)-3'), RNA polymerase sigma factor RpoS,RNA polymerase beta-flap-tip-helix
Authors:Lou, Y.C, Chien, C.Y, Chen, C, Hsu, C.H.
Deposit date:2018-09-10
Release date:2019-09-11
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (3.748 Å)
Cite:Structural basis for -35 element recognition by sigma4chimera proteins and their interactions with PmrA response regulator.
Proteins, 88, 2020
1TTY
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BU of 1tty by Molmil
Solution structure of sigma A region 4 from Thermotoga maritima
Descriptor: RNA polymerase sigma factor rpoD
Authors:Lambert, L.J, Wei, Y, Schirf, V, Demeler, B, Werner, M.H.
Deposit date:2004-06-23
Release date:2004-11-23
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:T4 AsiA blocks DNA recognition by remodeling sigma(70) region 4
Embo J., 23, 2004
1KU7
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BU of 1ku7 by Molmil
Crystal Structure of Thermus aquatics RNA Polymerase SigmaA Subunit Region 4 Bound to-35 Element DNA
Descriptor: 5'-D(*CP*CP*TP*TP*GP*AP*CP*AP*AP*AP*G)-3', 5'-D(*CP*CP*TP*TP*TP*GP*TP*CP*AP*AP*G)-3', sigma factor sigA
Authors:Campbell, E.A, Muzzin, O, Chlenov, M, Sun, J.L, Olson, C.A, Weinman, O, Trester-Zedlitz, M.L, Darst, S.A.
Deposit date:2002-01-21
Release date:2002-03-29
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure of the bacterial RNA polymerase promoter specificity sigma subunit.
Mol.Cell, 9, 2002
1KU3
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BU of 1ku3 by Molmil
Crystal Structure of Thermus aquaticus RNA Polymerase Sigma Subunit Fragment, Region 4
Descriptor: sigma factor sigA
Authors:Campbell, E.A, Muzzin, O, Chlenov, M, Sun, J.L, Olson, C.A, Weinman, O, Trester-Zedlitz, M.L, Darst, S.A.
Deposit date:2002-01-21
Release date:2002-04-03
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure of the bacterial RNA polymerase promoter specificity sigma subunit.
Mol.Cell, 9, 2002
6FI7
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BU of 6fi7 by Molmil
E.coli Sigma factor S (RpoS) Region 4
Descriptor: RNA polymerase sigma factor RpoS
Authors:Liu, B, Matthews, S.J.
Deposit date:2018-01-17
Release date:2018-06-06
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:T7 phage factor required for managing RpoS inEscherichia coli.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
1NR3
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BU of 1nr3 by Molmil
SOLUTION STRUCTURE OF THE PROTEIN MTH0916: THE NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET TT212
Descriptor: DNA-binding protein tfx
Authors:Shen, Y, Liu, G, Bhaskaran, R, Yee, A, Arrowsmith, C, Szyperski, T, Northeast Structural Genomics Consortium (NESG)
Deposit date:2003-01-23
Release date:2003-06-10
Last modified:2024-05-08
Method:SOLUTION NMR
Cite:SOLUTION STRUCTURE OF THE PROTEIN MTH0916: THE NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET TT212
To be Published
3HUG
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BU of 3hug by Molmil
Crystal structure of Mycobacterium tuberculosis anti-sigma factor RslA in complex with -35 promoter binding domain of sigL
Descriptor: PROBABLE CONSERVED MEMBRANE PROTEIN, RNA polymerase sigma factor, SULFATE ION, ...
Authors:Thakur, K.G, Gopal, B.
Deposit date:2009-06-14
Release date:2010-03-02
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Structural and biochemical bases for the redox sensitivity of Mycobacterium tuberculosis RslA
J.Mol.Biol., 397, 2010
1TLH
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BU of 1tlh by Molmil
T4 AsiA bound to sigma70 region 4
Descriptor: 10 kDa anti-sigma factor, RNA polymerase sigma factor rpoD
Authors:Lambert, L.J, Wei, Y, Schirf, V, Demeler, B, Werner, M.H.
Deposit date:2004-06-09
Release date:2004-11-23
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:T4 AsiA blocks DNA recognition by remodeling sigma(70) region 4
Embo J., 23, 2004
4G8X
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BU of 4g8x by Molmil
G1 ORF67 / Staphyloccus aureus sigmaA domain 4 complex
Descriptor: ORF067, RNA polymerase sigma factor rpoD
Authors:Darst, S.A, Osmundson, J.S, Montero-Diaz, C.M, Hochschild, A.
Deposit date:2012-07-23
Release date:2013-08-07
Method:X-RAY DIFFRACTION (3.001 Å)
Cite:Promoter-specific transcription inhibition in Staphylococcus aureus by a phage protein.
Cell(Cambridge,Mass.), 151, 2012
4G6D
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BU of 4g6d by Molmil
G1 ORF67 / Staphyloccus aureus sigmaA domain 4 complex
Descriptor: ORF067, RNA polymerase sigma factor rpoD
Authors:Darst, S.A, Osmundson, J.S.
Deposit date:2012-07-18
Release date:2013-01-23
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.9971 Å)
Cite:Promoter-specific transcription inhibition in Staphylococcus aureus by a phage protein.
Cell(Cambridge,Mass.), 151, 2012
4G94
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BU of 4g94 by Molmil
G1 ORF67 / Staphyloccus aureus sigmaA domain 4 complex
Descriptor: ORF067, RNA polymerase sigma factor rpoD
Authors:Darst, S.A, Osmundson, J.S, Montero-Diaz, C.M, Hochschild, A.
Deposit date:2012-07-23
Release date:2013-01-23
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.9971 Å)
Cite:Promoter-specific transcription inhibition in Staphylococcus aureus by a phage protein.
Cell(Cambridge,Mass.), 151, 2012
8HNP
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BU of 8hnp by Molmil
Archaeal transcription factor Mutant
Descriptor: Archaeal transcription regulator
Authors:Bae, D.W, Cha, S.S.
Deposit date:2022-12-08
Release date:2023-09-13
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (3.39 Å)
Cite:An archaeal transcription factor EnfR with a novel 'eighth note' fold controls hydrogen production of a hyperthermophilic archaeon Thermococcus onnurineus NA1.
Nucleic Acids Res., 51, 2023
8HNO
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BU of 8hno by Molmil
Archaeal transcription factor Wild type
Descriptor: Archaeal transcription regulator
Authors:Bae, D.W, Cha, S.S.
Deposit date:2022-12-08
Release date:2023-09-13
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.84 Å)
Cite:An archaeal transcription factor EnfR with a novel 'eighth note' fold controls hydrogen production of a hyperthermophilic archaeon Thermococcus onnurineus NA1.
Nucleic Acids Res., 51, 2023
8Y6U
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BU of 8y6u by Molmil
Cryo-EM structure of E.coli transcription initiation complex with transcription factor GcvA
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Lin, W, Shi, J.
Deposit date:2024-02-03
Release date:2024-06-05
Method:ELECTRON MICROSCOPY (3.97 Å)
Cite:NMR analysis of a loop-bulge structure of UUCGA pentaloop.
Biochem.Biophys.Res.Commun., 691, 2024
5D4E
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BU of 5d4e by Molmil
Crystal structure of Thermus thermophilus product complex for transcription initiation with 3'-dephosphate-CoA and CTP
Descriptor: CYTIDINE-5'-MONOPHOSPHATE, DEPHOSPHO COENZYME A, DIPHOSPHATE, ...
Authors:Zhang, Y, Ebright, R.H.
Deposit date:2015-08-07
Release date:2016-07-06
Last modified:2024-07-03
Method:X-RAY DIFFRACTION (3.08 Å)
Cite:The mechanism of RNA 5' capping with NAD(+), NADH and desphospho-CoA.
Nature, 535, 2016
2Z2S
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BU of 2z2s by Molmil
Crystal Structure of Rhodobacter sphaeroides SigE in complex with the anti-sigma ChrR
Descriptor: Anti-Sigma factor ChrR, transcriptional activator ChrR, RpoE, ...
Authors:Darst, S.A, Campbell, E.A.
Deposit date:2007-05-26
Release date:2008-02-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:A conserved structural module regulates transcriptional responses to diverse stress signals in bacteria.
Mol.Cell, 27, 2007
3WOD
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BU of 3wod by Molmil
RNA polymerase-gp39 complex
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Tagami, S, Sekine, S, Minakhin, L, Esyunina, D, Akasaka, R, Shirouzu, M, Kulbachinskiy, A, Severinov, K, Yokoyama, S.
Deposit date:2013-12-26
Release date:2014-03-12
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Structural basis for promoter specificity switching of RNA polymerase by a phage factor.
Genes Dev., 28, 2014
2W48
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BU of 2w48 by Molmil
Crystal structure of the Full-length Sorbitol Operon Regulator SorC from Klebsiella pneumoniae
Descriptor: (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, ...
Authors:de Sanctis, D, McVey, C.E, Enguita, F.J, Carrondo, M.A.
Deposit date:2008-11-21
Release date:2009-05-05
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Crystal Structure of the Full-Length Sorbitol Operon Regulator Sorc from Klebsiella Pneumoniae: Structural Evidence for a Novel Transcriptional Regulation Mechanism.
J.Mol.Biol., 387, 2009
3N97
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BU of 3n97 by Molmil
RNA polymerase alpha C-terminal domain (E. coli) and sigma region 4 (T. aq. mutant) bound to (UP,-35 element) DNA
Descriptor: ACETATE ION, DNA (5'-D(*CP*CP*AP*TP*GP*TP*CP*AP*AP*GP*TP*AP*CP*TP*TP*TP*TP*TP*TP*CP*C)-3'), DNA (5'-D(*TP*GP*GP*AP*AP*AP*AP*AP*AP*GP*TP*AP*CP*TP*TP*GP*AP*CP*AP*TP*GP*G)-3'), ...
Authors:Lara-Gonzalez, S, Birktoft, J.J, Lawson, C.L.
Deposit date:2010-05-28
Release date:2011-06-08
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (3.252 Å)
Cite:The RNA Polymerase alpha Subunit Recognizes the DNA Shape of the Upstream Promoter Element.
Biochemistry, 59, 2020
7C17
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BU of 7c17 by Molmil
The cryo-EM structure of E. coli CueR transcription activation complex with fully duplex promoter DNA
Descriptor: DNA (72-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:Fang, C.L, Zhang, Y.
Deposit date:2020-05-02
Release date:2020-09-30
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (4.22 Å)
Cite:CueR activates transcription through a DNA distortion mechanism.
Nat.Chem.Biol., 17, 2021
3T72
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BU of 3t72 by Molmil
PhoB(E)-Sigma70(4)-(RNAP-Betha-flap-tip-helix)-DNA Transcription Activation Sub-Complex
Descriptor: PHO BOX DNA (STRAND 1), PHO BOX DNA (STRAND 2), Phosphate regulon transcriptional regulatory protein phoB, ...
Authors:Blanco, A.G, Canals, A, Bernues, J, Sola, M, Coll, M.
Deposit date:2011-07-29
Release date:2011-09-21
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (4.33 Å)
Cite:The structure of a transcription activation subcomplex reveals how sigma (70) is recruited to PhoB promoters.
Embo J., 30, 2011
6DCF
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BU of 6dcf by Molmil
Crystal structure of a Mycobacterium smegmatis transcription initiation complex with Rifampicin-resistant RNA polymerase and bound to kanglemycin A
Descriptor: 1,2-ETHANEDIOL, DNA (26-MER), DNA (31-MER), ...
Authors:Lilic, M, Darst, S.A, Campbell, E.A.
Deposit date:2018-05-06
Release date:2018-09-05
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.45 Å)
Cite:Rifamycin congeners kanglemycins are active against rifampicin-resistant bacteria via a distinct mechanism.
Nat Commun, 9, 2018
6DVC
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BU of 6dvc by Molmil
Crystal structure of Mycobacterium tuberculosis transcription initiation complex(ECF sigma factor L) containing 5nt RNA with 6nt spacer
Descriptor: DNA (5'-D(*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*GP*AP*GP*G)-3'), DNA (5'-D(P*CP*GP*TP*GP*TP*CP*AP*GP*TP*AP*GP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*C)-3'), DNA-directed RNA polymerase subunit alpha, ...
Authors:Lin, W, Das, K, Feng, Y, Ebright, R.H.
Deposit date:2018-06-23
Release date:2019-02-20
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structural basis of ECF-sigma-factor-dependent transcription initiation.
Nat Commun, 10, 2019
8DY7
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BU of 8dy7 by Molmil
Streptomyces venezuelae RNAP transcription open promoter complex with WhiA and WhiB transcription factors
Descriptor: DNA (71-MER), DNA (78-MER), DNA-directed RNA polymerase subunit alpha, ...
Authors:Lilic, M, Campbell, E.A.
Deposit date:2022-08-03
Release date:2023-03-01
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3.18 Å)
Cite:Structural basis of dual activation of cell division by the actinobacterial transcription factors WhiA and WhiB.
Proc.Natl.Acad.Sci.USA, 120, 2023
8DY9
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BU of 8dy9 by Molmil
Streptomyces venezuelae RNAP unconstrained open promoter complex with WhiA and WhiB transcription factors
Descriptor: DNA (38-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:Lilic, M, Campbell, E.A.
Deposit date:2022-08-03
Release date:2023-03-01
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3.12 Å)
Cite:Structural basis of dual activation of cell division by the actinobacterial transcription factors WhiA and WhiB.
Proc.Natl.Acad.Sci.USA, 120, 2023

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數據於2024-07-10公開中

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