6DV2
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![BU of 6dv2 by Molmil](/molmil-images/mine/6dv2) | Crystal Structure of Human Mitochondrial Trifunctional Protein | Descriptor: | Trifunctional enzyme subunit alpha, mitochondrial, Trifunctional enzyme subunit beta | Authors: | Fu, Z, Xia, C, Battaile, K.P, Kim, J.P. | Deposit date: | 2018-06-22 | Release date: | 2018-09-26 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (3.6 Å) | Cite: | Crystal structure of human mitochondrial trifunctional protein, a fatty acid beta-oxidation metabolon. Proc. Natl. Acad. Sci. U.S.A., 116, 2019
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1M3K
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![BU of 1m3k by Molmil](/molmil-images/mine/1m3k) | biosynthetic thiolase, inactive C89A mutant | Descriptor: | Acetyl-CoA acetyltransferase, GLYCEROL, SULFATE ION | Authors: | Kursula, P, Ojala, J, Lambeir, A.-M, Wierenga, R.K. | Deposit date: | 2002-06-28 | Release date: | 2002-11-29 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | The catalytic cycle of biosynthetic thiolase: A conformational
journey of an acetyl group through four binding modes and two oxyanion holes Biochemistry, 41, 2002
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1AFW
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![BU of 1afw by Molmil](/molmil-images/mine/1afw) | |
5ONC
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![BU of 5onc by Molmil](/molmil-images/mine/5onc) | Catabolism of the Cholesterol Side Chain in Mycobacterium tuberculosis is Controlled by a Redox-Sensitive Thiol Switch | Descriptor: | CHLORIDE ION, Steroid 3-ketoacyl-CoA thiolase | Authors: | Schaefer, C, Kuper, J, Sampson, N.S, Kisker, C. | Deposit date: | 2017-08-03 | Release date: | 2017-08-23 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.19 Å) | Cite: | Catabolism of the Cholesterol Side Chain in Mycobacterium tuberculosis Is Controlled by a Redox-Sensitive Thiol Switch. ACS Infect Dis, 3, 2017
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4W61
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![BU of 4w61 by Molmil](/molmil-images/mine/4w61) | |
8ECM
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![BU of 8ecm by Molmil](/molmil-images/mine/8ecm) | |
5LP7
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![BU of 5lp7 by Molmil](/molmil-images/mine/5lp7) | |
4O99
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![BU of 4o99 by Molmil](/molmil-images/mine/4o99) | Crystal structure of Beta-ketothiolase (PhaA) from Ralstonia eutropha H16 | Descriptor: | Acetyl-CoA acetyltransferase, GLYCEROL | Authors: | Kim, E.J, Kim, J, Kim, S, Kim, K.J. | Deposit date: | 2014-01-02 | Release date: | 2014-12-17 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.96 Å) | Cite: | Crystal structure and biochemical characterization of PhaA from Ralstonia eutropha, a polyhydroxyalkanoate-producing bacterium. Biochem.Biophys.Res.Commun., 452, 2014
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1ULQ
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![BU of 1ulq by Molmil](/molmil-images/mine/1ulq) | Crystal structure of tt0182 from Thermus thermophilus HB8 | Descriptor: | putative acetyl-CoA acetyltransferase | Authors: | Ago, H, Hamada, K, Ida, K, Kanda, H, Sugahara, M, Yamamoto, M, Kuroishi, C, Kuramitsu, S, Yokoyama, S, Miyano, M, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2003-09-16 | Release date: | 2004-11-02 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Crystal structure of tt0182 from Thermus thermophilus HB8 To be Published
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3GOA
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![BU of 3goa by Molmil](/molmil-images/mine/3goa) | Crystal structure of the Salmonella typhimurium FadA 3-ketoacyl-CoA thiolase | Descriptor: | 3-ketoacyl-CoA thiolase, CALCIUM ION, CHLORIDE ION, ... | Authors: | Anderson, S.M, Skarina, T, Onopriyenko, O, Wawrzak, Z, Papazisi, L, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2009-03-18 | Release date: | 2009-03-31 | Last modified: | 2017-11-01 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: |
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5XYJ
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6L2G
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![BU of 6l2g by Molmil](/molmil-images/mine/6l2g) | Crystal structure of Aspergillus fumigatus mitochondrial acetyl-CoA acetyltransferase | Descriptor: | Acetyl-CoA-acetyltransferase, putative | Authors: | Zhang, Y, Wei, W, Raimi, O.G, Ferenbach, A.T, Fang, W. | Deposit date: | 2019-10-03 | Release date: | 2020-02-12 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.41 Å) | Cite: | Aspergillus fumigatus Mitochondrial Acetyl Coenzyme A Acetyltransferase as an Antifungal Target. Appl.Environ.Microbiol., 86, 2020
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5F0V
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![BU of 5f0v by Molmil](/molmil-images/mine/5f0v) | X-ray crystal structure of a thiolase from Escherichia coli at 1.8 A resolution | Descriptor: | 1,2-ETHANEDIOL, Acetyl-CoA acetyltransferase | Authors: | Ithayaraja, M, Neelanjana, J, Wierenga, R, Savithri, H.S, Murthy, M.R.N. | Deposit date: | 2015-11-28 | Release date: | 2016-07-13 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal structure of a thiolase from Escherichia coli at 1.8 angstrom resolution. Acta Crystallogr.,Sect.F, 72, 2016
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6L2C
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![BU of 6l2c by Molmil](/molmil-images/mine/6l2c) | Crystal structure of Aspergillus fumigatus mitochondrial acetyl-CoA acetyltransferase in complex with CoA | Descriptor: | Acetyl-CoA-acetyltransferase, putative, COENZYME A | Authors: | Zhang, Y, Wei, W, Raimi, O.G, Ferenbach, A.T, Fang, W. | Deposit date: | 2019-10-03 | Release date: | 2020-02-12 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.44 Å) | Cite: | Aspergillus fumigatus Mitochondrial Acetyl Coenzyme A Acetyltransferase as an Antifungal Target. Appl.Environ.Microbiol., 86, 2020
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5F38
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![BU of 5f38 by Molmil](/molmil-images/mine/5f38) | X-ray crystal structure of a thiolase from Escherichia coli at 1.8 A resolution | Descriptor: | 1,2-ETHANEDIOL, Acetyl-CoA acetyltransferase, COENZYME A, ... | Authors: | Ithayaraja, M, Neelanjana, J, Wierenga, R, Savithri, H.S, Murthy, M.R.N. | Deposit date: | 2015-12-02 | Release date: | 2016-07-13 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structure of a thiolase from Escherichia coli at 1.8 angstrom resolution. Acta Crystallogr.,Sect.F, 72, 2016
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5XZ5
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![BU of 5xz5 by Molmil](/molmil-images/mine/5xz5) | |
7VTR
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![BU of 7vtr by Molmil](/molmil-images/mine/7vtr) | 3-ketoacyl-CoA thiolase Tfu_0875 | Descriptor: | Thiolase | Authors: | Liu, L.X, Zhou, S.H, Deng, Y. | Deposit date: | 2021-10-30 | Release date: | 2022-11-02 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.93 Å) | Cite: | Rational Design of the Substrate Tunnel of beta-Ketothiolase Reveals a Local Cationic Domain Modulated Rule that Improves the Efficiency of Claisen Condensation Acs Catalysis, 13, 2023
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3SVK
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3SS6
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![BU of 3ss6 by Molmil](/molmil-images/mine/3ss6) | Crystal structure of the Bacillus anthracis acetyl-CoA acetyltransferase | Descriptor: | Acetyl-CoA acetyltransferase, POTASSIUM ION, SULFATE ION | Authors: | Anderson, S.M, Wawrzak, Z, Onopriyenko, O, Peterson, S.N, Anderson, W.F, Savchenko, A, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2011-07-07 | Release date: | 2011-07-20 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Crystal structure of the Bacillus anthracis acetyl-CoA acetyltransferase TO BE PUBLISHED
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7XLY
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![BU of 7xly by Molmil](/molmil-images/mine/7xly) | Crystal structure of FadA2 (Rv0243) from the fatty acid metabolic pathway of Mycobacterium tuberculosis | Descriptor: | Probable acetyl-CoA acyltransferase FadA2 (3-ketoacyl-CoA thiolase) (Beta-ketothiolase), SULFATE ION | Authors: | Singh, R, Kundu, P, Singh, B.K, Bhattacharyya, S, Das, A.K. | Deposit date: | 2022-04-23 | Release date: | 2023-04-26 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Crystal structure of FadA2 thiolase from Mycobacterium tuberculosis and prediction of its substrate specificity and membrane-anchoring properties. Febs J., 290, 2023
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4NZS
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8BNR
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![BU of 8bnr by Molmil](/molmil-images/mine/8bnr) | Escherichia coli anaerobic fatty acid beta oxidation trifunctional enzyme (anEcTFE) octameric complex | Descriptor: | 3-ketoacyl-CoA thiolase FadI, Fatty acid oxidation complex subunit alpha | Authors: | Sah-Teli, S.K, Pinkas, M, Novacek, J, Venkatesan, R. | Deposit date: | 2022-11-14 | Release date: | 2023-05-17 | Last modified: | 2023-11-29 | Method: | ELECTRON MICROSCOPY (10.3 Å) | Cite: | Structural basis for different membrane-binding properties of E. coli anaerobic and human mitochondrial beta-oxidation trifunctional enzymes. Structure, 31, 2023
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7CW4
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![BU of 7cw4 by Molmil](/molmil-images/mine/7cw4) | Acetyl-CoA acetyltransferase from Bacillus cereus ATCC 14579 | Descriptor: | Acetyl-CoA acetyltransferase, GLYCEROL | Authors: | Hong, J, Kim, K.J. | Deposit date: | 2020-08-27 | Release date: | 2020-10-07 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.56 Å) | Cite: | Crystal structure of an acetyl-CoA acetyltransferase from PHB producing bacterium Bacillus cereus ATCC 14579. Biochem.Biophys.Res.Commun., 533, 2020
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4O9C
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![BU of 4o9c by Molmil](/molmil-images/mine/4o9c) | Crystal structure of Beta-ketothiolase (PhaA) from Ralstonia eutropha H16 | Descriptor: | Acetyl-CoA acetyltransferase, COENZYME A | Authors: | Kim, E.J, Kim, J, Kim, S, Kim, K.J. | Deposit date: | 2014-01-02 | Release date: | 2014-12-17 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structure and biochemical characterization of PhaA from Ralstonia eutropha, a polyhydroxyalkanoate-producing bacterium. Biochem.Biophys.Res.Commun., 452, 2014
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1DLU
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![BU of 1dlu by Molmil](/molmil-images/mine/1dlu) | UNLIGANDED BIOSYNTHETIC THIOLASE FROM ZOOGLOEA RAMIGERA | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, BIOSYNTHETIC THIOLASE, SULFATE ION | Authors: | Modis, Y, Wierenga, R.K. | Deposit date: | 1999-12-12 | Release date: | 2000-04-24 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Crystallographic analysis of the reaction pathway of Zoogloea ramigera biosynthetic thiolase. J.Mol.Biol., 297, 2000
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