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4MCU
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BU of 4mcu by Molmil
Crystal structure of disulfide oxidoreductase from Klebsiella pneumoniae in reduced state
Descriptor: Thiol:disulfide interchange protein
Authors:Kurth, F, Premkumar, L, Martin, J.L.
Deposit date:2013-08-21
Release date:2013-11-27
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Comparative Sequence, Structure and Redox Analyses of Klebsiella pneumoniae DsbA Show That Anti-Virulence Target DsbA Enzymes Fall into Distinct Classes.
Plos One, 8, 2013
6DXN
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BU of 6dxn by Molmil
1.95 Angstrom Resolution Crystal Structure of DsbA Disulfide Interchange Protein from Klebsiella pneumoniae.
Descriptor: TRIETHYLENE GLYCOL, Thiol:disulfide interchange protein
Authors:Minasov, G, Wawrzak, Z, Shuvalova, L, Kiryukhina, O, Endres, M, Satchell, K.J.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2018-06-29
Release date:2018-07-11
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:A Structural Systems Biology Approach to High-Risk CG23 Klebsiella pneumoniae.
Microbiol Resour Announc, 12, 2023
1R4W
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BU of 1r4w by Molmil
Crystal structure of Mitochondrial class kappa glutathione transferase
Descriptor: GLUTATHIONE, Glutathione S-transferase, mitochondrial
Authors:Ladner, J.E, Parsons, J.F, Rife, C.L, Gilliland, G.L, Armstrong, R.N.
Deposit date:2003-10-08
Release date:2004-02-03
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Parallel Evolutionary Pathways for Glutathione Transferases: Structure and Mechanism of the Mitochondrial Class Kappa Enzyme rGSTK1-1
Biochemistry, 43, 2004
7TTV
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BU of 7ttv by Molmil
E.coli DsbA in complex with 4-phenyl-2-(3-phenylpropyl)thiazole-5-carboxylic acid
Descriptor: 4-phenyl-2-(3-phenylpropyl)-1,3-thiazole-5-carboxylic acid, COPPER (II) ION, Thiol:disulfide interchange protein DsbA
Authors:Wang, G, Heras, B.
Deposit date:2022-02-02
Release date:2023-04-12
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Methyl probes in proteins for determining ligand binding mode in weak protein-ligand complexes.
Sci Rep, 12, 2022
5XWH
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BU of 5xwh by Molmil
Structure of FrnE, a novel disulfide oxidoreductase from Deinococcus radiodurans crystallized in the presence of GSH
Descriptor: FrnE protein
Authors:Bihani, S.C, Panicker, L, Kumar, V.
Deposit date:2017-06-29
Release date:2018-07-04
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of FrnE, a novel disulfide oxidoreductase from Deinococcus radiodurans crystallized in the presence of GSH
To Be Published
4TKY
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BU of 4tky by Molmil
The complex structure of E. coli DsbA bound to a peptide at the DsbA/DsbB interface
Descriptor: ACETYL GROUP, AMINO GROUP, PRO-PHE-ALA-THR-CYS-ASP-SER, ...
Authors:Premkumar, L, Martin, J.L.
Deposit date:2014-05-28
Release date:2015-01-14
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Peptide Inhibitors of the Escherichia coli DsbA Oxidative Machinery Essential for Bacterial Virulence.
J.Med.Chem., 58, 2015
6PVY
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BU of 6pvy by Molmil
E.coli DsbA in complex with benzofuran compound 26 ([6-(3-methoxyphenoxy)-1-benzofuran-3-yl]acetic acid)
Descriptor: COPPER (II) ION, DI(HYDROXYETHYL)ETHER, DIMETHYL SULFOXIDE, ...
Authors:Wang, G, Heras, B.
Deposit date:2019-07-21
Release date:2019-12-25
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.74 Å)
Cite:The Fragment-Based Development of a Benzofuran Hit as a New Class of Escherichia coli DsbA Inhibitors.
Molecules, 24, 2019
2REM
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BU of 2rem by Molmil
Crystal Structure of oxidoreductase DsbA from Xylella fastidiosa
Descriptor: 8 residue peptide, Disulfide oxidoreductase
Authors:Rinaldi, F.C, Guimaraes, B.G.
Deposit date:2007-09-26
Release date:2008-10-07
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Residues substitution in the active site of DSBA may compensate for the lack of the canonical motif CPHC
To be Published
7DKA
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BU of 7dka by Molmil
Crystal structure of DsbA-like protein DR2335 from Deinococcus radiodurans R1, C24S mutant protein
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ACETATE ION, DI(HYDROXYETHYL)ETHER, ...
Authors:Kim, M.-K, Zhang, J, Zhao, L.
Deposit date:2020-11-23
Release date:2021-11-24
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.56 Å)
Cite:Crystal structure of DsbA-like protein DR2335 from Deinococcus radiodurans R1, native protein
To Be Published
7DK9
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BU of 7dk9 by Molmil
Crystal structure of DsbA-like protein DR2335 from Deinococcus radiodurans R1, native protein
Descriptor: DI(HYDROXYETHYL)ETHER, DSBA domain-containing protein, PHOSPHATE ION
Authors:Kim, M.-K, Zhang, J, Zhao, L.
Deposit date:2020-11-23
Release date:2021-11-24
Method:X-RAY DIFFRACTION (1.72 Å)
Cite:Crystal structure of DsbA-like protein DR2335 from Deinococcus radiodurans R1, native protein
To Be Published
7PQ8
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BU of 7pq8 by Molmil
Crystal structure of Campylobacter jejuni DsbA1
Descriptor: TETRAETHYLENE GLYCOL, Thiol:disulfide interchange protein DsbA
Authors:Orlikowska, M, Bocian-Ostrzycka, K.M, Banas, A.M, Jagusztyn-Krynicka, E.K.
Deposit date:2021-09-16
Release date:2021-12-29
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.329 Å)
Cite:Interplay between DsbA1, DsbA2 and C8J_1298 Periplasmic Oxidoreductases of Campylobacter jejuni and Their Impact on Bacterial Physiology and Pathogenesis.
Int J Mol Sci, 22, 2021
7PQ7
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BU of 7pq7 by Molmil
Crystal structure of Campylobacter jejuni DsbA1
Descriptor: TETRAETHYLENE GLYCOL, TRIETHYLENE GLYCOL, Thiol:disulfide interchange protein DsbA
Authors:Wilk, P, Orlikowska, M, Banas, A.M, Bocian-Ostrzycka, K.M, Jagusztyn-Krynicka, E.K.
Deposit date:2021-09-16
Release date:2021-12-29
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Interplay between DsbA1, DsbA2 and C8J_1298 Periplasmic Oxidoreductases of Campylobacter jejuni and Their Impact on Bacterial Physiology and Pathogenesis.
Int J Mol Sci, 22, 2021
5HFI
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BU of 5hfi by Molmil
Cytosolic disulfide reductase DsbM from Pseudomonas aeruginosa with GSH
Descriptor: GLUTATHIONE, Uncharacterized protein, cytosolic disulfide reductase DsbM
Authors:Jo, I, Ha, N.-C.
Deposit date:2016-01-07
Release date:2016-10-26
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.801 Å)
Cite:Crystal structures of the disulfide reductase DsbM from Pseudomonas aeruginosa
Acta Crystallogr D Struct Biol, 72, 2016
4DVC
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BU of 4dvc by Molmil
Structural and functional studies of TcpG, the Vibrio cholerae DsbA disulfide-forming protein required for pilus and cholera toxin production
Descriptor: DIMETHYL SULFOXIDE, SULFATE ION, Thiol:disulfide interchange protein DsbA
Authors:Walden, P.M, Martin, J.L.
Deposit date:2012-02-23
Release date:2012-10-31
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:The 1.2 A resolution crystal structure of TcpG, the Vibrio cholerae DsbA disulfide-forming protein required for pilus and cholera-toxin production
Acta Crystallogr.,Sect.D, 68, 2012
5HFG
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BU of 5hfg by Molmil
Cytosolic disulfide reductase DsbM from Pseudomonas aeruginosa
Descriptor: Uncharacterized protein, cytosolic disulfide reductase DsbM
Authors:Jo, I, Ha, N.-C.
Deposit date:2016-01-07
Release date:2016-10-26
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.823 Å)
Cite:Crystal structures of the disulfide reductase DsbM from Pseudomonas aeruginosa
Acta Crystallogr D Struct Biol, 72, 2016
3RPN
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BU of 3rpn by Molmil
Crystal structure of human kappa class glutathione transferase in complex with S-hexylglutathione
Descriptor: Glutathione S-transferase kappa 1, S-HEXYLGLUTATHIONE
Authors:Wang, B, Peng, Y, Zhang, T, Ding, J.
Deposit date:2011-04-27
Release date:2011-07-13
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structures and kinetic studies of human Kappa class glutathione transferase provide insights into the catalytic mechanism.
Biochem.J., 439, 2011
6BR4
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BU of 6br4 by Molmil
Crystal structure of Escherichia coli DsbA in complex with {N}-methyl-1-(3-thiophen-2-ylphenyl)methanamine
Descriptor: COPPER (II) ION, Thiol:disulfide interchange protein DsbA, ~{N}-methyl-1-(3-thiophen-2-ylphenyl)methanamine
Authors:Heras, B, Totsika, M, Paxman, J.J, Wang, G, Scanlon, M.J, Martin, J.L.
Deposit date:2017-11-29
Release date:2017-12-27
Last modified:2020-01-01
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Inhibition of Diverse DsbA Enzymes in Multi-DsbA Encoding Pathogens.
Antioxid. Redox Signal., 29, 2018
7L7C
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BU of 7l7c by Molmil
Crystal Structure of EcDsbA in a complex with 2-(6-(3-Methoxyphenyl)benzofuran-3-yl)acetic acid
Descriptor: COPPER (II) ION, Thiol:disulfide interchange protein DsbA, [6-(3-methoxyphenyl)-1-benzofuran-3-yl]acetic acid
Authors:Ilyichova, O.V, Scanlon, M.J.
Deposit date:2020-12-28
Release date:2021-08-11
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Elaboration of a benzofuran scaffold and evaluation of binding affinity and inhibition of Escherichia coli DsbA: A fragment-based drug design approach to novel antivirulence compounds.
Bioorg.Med.Chem., 45, 2021
7L76
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BU of 7l76 by Molmil
Crystal Structure of EcDsbA in a complex with 2-(6-Phenylbenzofuran-3-yl)acetic acid
Descriptor: (6-phenyl-1-benzofuran-3-yl)acetic acid, COPPER (II) ION, Thiol:disulfide interchange protein DsbA
Authors:Ilyichova, O.V, Scanlon, M.J.
Deposit date:2020-12-26
Release date:2021-08-11
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.83 Å)
Cite:Elaboration of a benzofuran scaffold and evaluation of binding affinity and inhibition of Escherichia coli DsbA: A fragment-based drug design approach to novel antivirulence compounds.
Bioorg.Med.Chem., 45, 2021
4K2D
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BU of 4k2d by Molmil
Crystal structure of Burkholderia Pseudomallei DsbA
Descriptor: GLYCEROL, Thiol:disulfide interchange protein
Authors:McMahon, R.M.
Deposit date:2013-04-09
Release date:2013-08-14
Last modified:2014-02-12
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Disarming Burkholderia pseudomallei: Structural and Functional Characterization of a Disulfide Oxidoreductase (DsbA) Required for Virulence In Vivo.
Antioxid Redox Signal, 20, 2014
5TLQ
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BU of 5tlq by Molmil
Model structure of the oxidized PaDsbA1 and 3-[(2-methylbenzyl)sulfanyl]-4H-1,2,4-triazol-4-amine complex
Descriptor: 3-[(2-methylbenzyl)sulfanyl]-4H-1,2,4-triazol-4-amine, Thiol:disulfide interchange protein DsbA
Authors:Mohanty, B, Rimmer, K.A, McMahon, R.M, Headey, S.J, Vazirani, M, Shouldice, S.R, Coincon, M, Tay, S, Morton, C.J, Simpson, J.S, Martin, J.L, Scanlon, M.S.
Deposit date:2016-10-11
Release date:2017-04-12
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Fragment library screening identifies hits that bind to the non-catalytic surface of Pseudomonas aeruginosa DsbA1.
PLoS ONE, 12, 2017
6BQX
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BU of 6bqx by Molmil
Crystal structure of Escherichia coli DsbA in complex with N-methyl-1-(4-phenoxyphenyl)methanamine
Descriptor: N-methyl-1-(4-phenoxyphenyl)methanamine, Thiol:disulfide interchange protein DsbA
Authors:Heras, B, Totsika, M, Paxman, J.J, Wang, G, Scanlon, M.J.
Deposit date:2017-11-29
Release date:2017-12-27
Last modified:2020-01-01
Method:X-RAY DIFFRACTION (1.992 Å)
Cite:Inhibition of Diverse DsbA Enzymes in Multi-DsbA Encoding Pathogens.
Antioxid. Redox Signal., 29, 2018
3RPP
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BU of 3rpp by Molmil
Crystal structure of human kappa class glutathione transferase in apo form
Descriptor: Glutathione S-transferase kappa 1
Authors:Wang, B, Peng, Y, Zhang, T, Ding, J.
Deposit date:2011-04-27
Release date:2011-07-13
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structures and kinetic studies of human Kappa class glutathione transferase provide insights into the catalytic mechanism.
Biochem.J., 439, 2011
4JRR
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BU of 4jrr by Molmil
Crystal structure of disulfide bond oxidoreductase DsbA1 from Legionella pneumophila
Descriptor: GLYCEROL, SULFATE ION, Thiol:disulfide interchange protein DsbA
Authors:Shumilin, I.A, Jameson-Lee, M, Cymborowski, M, Domagalski, M.J, Chertihin, O, Kpadeh, Z.Z, Yeh, A.J, Hoffman, P.S, Anderson, W.F, Minor, W, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2013-03-21
Release date:2013-04-24
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:Crystal structure of disulfide bond oxidoreductase DsbA1 from Legionella pneumophila
To be Published
1FVJ
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BU of 1fvj by Molmil
THE 2.06 ANGSTROM STRUCTURE OF THE H32Y MUTANT OF THE DISULFIDE BOND FORMATION PROTEIN (DSBA)
Descriptor: DISULFIDE BOND FORMATION PROTEIN
Authors:Martin, J.L, Guddat, L.W.
Deposit date:1996-08-28
Release date:1997-05-15
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.06 Å)
Cite:Structural analysis of three His32 mutants of DsbA: support for an electrostatic role of His32 in DsbA stability.
Protein Sci., 6, 1997

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數據於2024-09-11公開中

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