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9BH6
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BU of 9bh6 by Molmil
Human DNA polymerase theta helicase domain tetramer in the apo form
Descriptor: DNA polymerase theta
Authors:Zerio, C.J, Lander, G.C.
Deposit date:2024-04-19
Release date:2024-05-01
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Human polymerase theta helicase positions DNA microhomologies for double-strand break repair
To Be Published
9BH9
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BU of 9bh9 by Molmil
Human DNA polymerase theta helicase domain dimer bound to DNA in the microhomology aligning conformation
Descriptor: DNA polymerase theta, Stem-loop DNA with microhomology in the 3' overhang
Authors:Zerio, C.J, Lander, G.C.
Deposit date:2024-04-19
Release date:2024-05-01
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Human polymerase theta helicase positions DNA microhomologies for double-strand break repair
To Be Published
9BHA
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BU of 9bha by Molmil
Human DNA polymerase theta helicase domain dimer bound to DNA in the microhomology annealed conformation
Descriptor: DNA polymerase theta, Stem-loop DNA with microhomology in the 3' overhang
Authors:Zerio, C.J, Lander, G.C.
Deposit date:2024-04-19
Release date:2024-05-01
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Human polymerase theta helicase positions DNA microhomologies for double-strand break repair
To Be Published
9BH8
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BU of 9bh8 by Molmil
Human DNA polymerase theta helicase domain dimer bound to DNA in the microhomology searching conformation
Descriptor: DNA polymerase theta, Stem-loop DNA with microhomology in the 3' overhang
Authors:Zerio, C.J, Lander, G.C.
Deposit date:2024-04-19
Release date:2024-05-01
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Human polymerase theta helicase positions DNA microhomologies for double-strand break repair
To Be Published
9BH7
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BU of 9bh7 by Molmil
Human DNA polymerase theta helicase domain dimer in the apo form
Descriptor: DNA polymerase theta
Authors:Zerio, C.J, Lander, G.C.
Deposit date:2024-04-19
Release date:2024-05-01
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Human polymerase theta helicase positions DNA microhomologies for double-strand break repair
To Be Published
8YLE
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BU of 8yle by Molmil
Crystal structure of Werner syndrome helicase complexed with AMP-PCP
Descriptor: 1,2-ETHANEDIOL, Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, ...
Authors:Yang, Y, Fu, L, Sun, X, Cheng, H, Chen, R.
Deposit date:2024-03-06
Release date:2024-04-10
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Structure of werner syndrome helicase complexed with AMP-PCP at 1.86 Angstroms resolution.
To Be Published
8VXY
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BU of 8vxy by Molmil
Structure of HamA(E138A,K140A)B-plasmid DNA complex from the Escherichia coli Hachiman defense system
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, HamA, HamB, ...
Authors:Tuck, O.T, Hu, J.J, Doudna, J.A.
Deposit date:2024-02-06
Release date:2024-03-13
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.19 Å)
Cite:Hachiman is a genome integrity sensor.
Biorxiv, 2024
8VXC
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BU of 8vxc by Molmil
Structure of HamB-DNA complex, conformation 2, from the Escherichia coli Hachiman defense system
Descriptor: DNA (40-MER), HamB
Authors:Tuck, O.T, Doudna, J.A.
Deposit date:2024-02-04
Release date:2024-03-13
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (2.93 Å)
Cite:Hachiman is a genome integrity sensor.
Biorxiv, 2024
8VXA
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BU of 8vxa by Molmil
Structure of HamB-DNA complex, conformation 1, from the Escherichia coli Hachiman defense system
Descriptor: DNA (40-MER), HamB
Authors:Tuck, O.T, Doudna, J.A.
Deposit date:2024-02-03
Release date:2024-03-13
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (2.79 Å)
Cite:Hachiman is a genome integrity sensor.
Biorxiv, 2024
8VX9
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BU of 8vx9 by Molmil
Structure of HamAB apo complex from the Escherichia coli Hachiman defense system
Descriptor: HamA, HamB
Authors:Tuck, O.T, Doudna, J.A.
Deposit date:2024-02-03
Release date:2024-03-13
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (2.65 Å)
Cite:Hachiman is a genome integrity sensor.
Biorxiv, 2024
8Y6O
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BU of 8y6o by Molmil
Cryo-EM Structure of the human minor pre-B complex (pre-precatalytic spliceosome) U11 and tri-snRNP part
Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, Centrosomal AT-AC splicing factor, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Bai, R, Yuan, M, Zhang, P, Luo, T, Shi, Y, Wan, R.
Deposit date:2024-02-02
Release date:2024-03-20
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.38 Å)
Cite:Structural basis of U12-type intron engagement by the fully assembled human minor spliceosome.
Science, 383, 2024
8XXN
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BU of 8xxn by Molmil
Cryo-EM structure of the human 43S ribosome with PDCD4
Descriptor: 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ...
Authors:Ye, X, Huang, Z, Li, Y, Wang, M, Cheng, J.
Deposit date:2024-01-18
Release date:2024-05-01
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Human tumor suppressor PDCD4 directly interacts with ribosomes to repress translation.
Cell Res., 2024
8RM5
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BU of 8rm5 by Molmil
Cryo-EM structure of the cross-exon pre-B+5'ssLNG+ATPyS complex
Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, 5'SS oligo, NHP2-like protein 1, ...
Authors:Zhang, Z, Kumar, V, Dybkov, O, Will, C.L, Zhong, J, Ludwig, S, Urlaub, H, Kastner, B, Stark, H, Luehrmann, R.
Deposit date:2024-01-05
Release date:2024-05-22
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (6.9 Å)
Cite:Structural insights into the cross-exon to cross-intron spliceosome switch.
Nature, 2024
8RC0
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BU of 8rc0 by Molmil
Structure of the human 20S U5 snRNP
Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, CD2 antigen cytoplasmic tail-binding protein 2, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Schneider, S, Galej, W.P.
Deposit date:2023-12-05
Release date:2024-03-27
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structure of the human 20S U5 snRNP.
Nat.Struct.Mol.Biol., 31, 2024
8V87
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BU of 8v87 by Molmil
60S ribosome biogenesis intermediate (Dbp10 post-catalytic structure - Overall map)
Descriptor: 25S rRNA (cytosine(2870)-C(5))-methyltransferase, 25S ribosomal RNA, 27S pre-rRNA (guanosine(2922)-2'-O)-methyltransferase, ...
Authors:Cruz, V.E, Weirich, C.S, Peddada, N, Erzberger, J.P.
Deposit date:2023-12-04
Release date:2024-05-01
Method:ELECTRON MICROSCOPY (2.66 Å)
Cite:The DEAD-box ATPase Dbp10/DDX54 initiates peptidyl transferase center formation during 60S ribosome biogenesis.
Nat Commun, 15, 2024
8V83
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BU of 8v83 by Molmil
60S ribosome biogenesis intermediate (Dbp10 pre-catalytic structure - Overall map)
Descriptor: 25S rRNA (cytosine(2870)-C(5))-methyltransferase, 60S ribosomal protein L13-A, 60S ribosomal protein L14-A, ...
Authors:Cruz, V.E, Weirich, C.S, Peddada, N, Erzberger, J.P.
Deposit date:2023-12-04
Release date:2024-05-01
Method:ELECTRON MICROSCOPY (2.53 Å)
Cite:The DEAD-box ATPase Dbp10/DDX54 initiates peptidyl transferase center formation during 60S ribosome biogenesis.
Nat Commun, 15, 2024
8V85
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BU of 8v85 by Molmil
60S ribosome biogenesis intermediate (Dbp10 catalytic structure - Low-pass filtered locally refined map)
Descriptor: ATP-dependent RNA helicase DBP10
Authors:Cruz, V.E, Weirich, C.S, Peddada, N, Erzberger, J.P.
Deposit date:2023-12-04
Release date:2024-05-01
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:The DEAD-box ATPase Dbp10/DDX54 initiates peptidyl transferase center formation during 60S ribosome biogenesis.
Nat Commun, 15, 2024
8V84
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BU of 8v84 by Molmil
60S ribosome biogenesis intermediate (Dbp10 catalytic structure - Overall map)
Descriptor: 25S rRNA (cytosine(2870)-C(5))-methyltransferase, 60S ribosomal protein L13-A, 60S ribosomal protein L14-A, ...
Authors:Cruz, V.E, Weirich, C.S, Peddada, N, Erzberger, J.P.
Deposit date:2023-12-04
Release date:2024-05-01
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:The DEAD-box ATPase Dbp10/DDX54 initiates peptidyl transferase center formation during 60S ribosome biogenesis.
Nat Commun, 15, 2024
8R0B
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BU of 8r0b by Molmil
Cryo-EM structure of the cross-exon pre-B+ATP complex
Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, 5'ss oligo, NHP2-like protein 1, ...
Authors:Zhang, Z, Kumar, V, Dybkov, O, Will, C.L, Zhong, J, Ludwig, S, Urlaub, H, Kastner, B, Stark, H, Luehrmann, R.
Deposit date:2023-10-31
Release date:2024-05-22
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:Structural insights into the cross-exon to cross-intron spliceosome switch.
Nature, 2024
8R08
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BU of 8r08 by Molmil
Cryo-EM structure of the cross-exon pre-B+AMPPNP complex
Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, NHP2-like protein 1, N-terminally processed, ...
Authors:Zhang, Z, Kumar, V, Dybkov, O, Will, C.L, Zhong, J, Ludwig, S, Urlaub, H, Kastner, B, Stark, H, Luehrmann, R.
Deposit date:2023-10-31
Release date:2024-05-22
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (6.1 Å)
Cite:Structural insights into the cross-exon to cross-intron spliceosome switch.
Nature, 2024
8R0A
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BU of 8r0a by Molmil
Cryo-EM structure of the cross-exon pre-B+5'ss complex
Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, 5'ss oligo, NHP2-like protein 1, ...
Authors:Zhang, Z, Kumar, V, Dybkov, O, Will, C.L, Zhong, J, Ludwig, S, Urlaub, H, Kastner, B, Stark, H, Luehrmann, R.
Deposit date:2023-10-31
Release date:2024-05-22
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (5.8 Å)
Cite:Structural insights into the cross-exon to cross-intron spliceosome switch.
Nature, 2024
8R09
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BU of 8r09 by Molmil
Cryo-EM structure of the cross-exon pre-B+5'ss+ATPgammaS complex
Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, 5'ss oligo, NHP2-like protein 1, ...
Authors:Zhang, Z, Kumar, V, Dybkov, O, Will, C.L, Zhong, J, Ludwig, S, Urlaub, H, Kastner, B, Stark, H, Luehrmann, R.
Deposit date:2023-10-31
Release date:2024-05-22
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Structural insights into the cross-exon to cross-intron spliceosome switch.
Nature, 2024
8QZS
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BU of 8qzs by Molmil
Cryo-EM structure of the cross-exon B-like complex
Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, Microfibrillar-associated protein 1, NHP2-like protein 1, ...
Authors:Zhang, Z, Kumar, V, Dybkov, O, Will, C.L, Zhong, J, Ludwig, S, Urlaub, H, Kastner, B, Stark, H, Luehrmann, R.
Deposit date:2023-10-29
Release date:2024-05-22
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Structural insights into the cross-exon to cross-intron spliceosome switch.
Nature, 2024
8QXD
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BU of 8qxd by Molmil
Cryo-EM structure of the cross-exon pre-B complex
Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, NHP2-like protein 1, N-terminally processed, ...
Authors:Zhang, Z, Kumar, V, Dybkov, O, Will, C.L, Zhong, J, Ludwig, S, Urlaub, H, Kastner, B, Stark, H, Luehrmann, R.
Deposit date:2023-10-24
Release date:2024-05-22
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (9.6 Å)
Cite:Structural insights into the cross-exon to cross-intron spliceosome switch.
Nature, 2024
7GQS
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BU of 7gqs by Molmil
Crystal Structure of Werner helicase fragment 517-945 in complex with ADP
Descriptor: 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN, ...
Authors:Classen, M, Benz, J, Brugger, D, Rudolph, M.G.
Deposit date:2023-10-19
Release date:2024-05-01
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (1.57 Å)
Cite:Chemoproteomic discovery of a covalent allosteric inhibitor of WRN helicase.
Nature, 629, 2024

221051

數據於2024-06-12公開中

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