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9C5E	Covalent Complex Between Parkin Catalytic (Rcat) Domain and Ubiquitin Descriptor: 1.7.6 3-bromanylpropan-1-amine, E3 ubiquitin-protein ligase parkin, Ubiquitin, ... Authors: Connelly, E.M, Rintala-Dempsey, A.C, Gundogdu, M, Freeman, E.A, Koszela, J, Aguirre, J.D, Zhu, G, Kamarainen, O, Tadayon, R, Walden, H, Shaw, G.S. Deposit date: 2024-06-06 Release date: 2024-08-14 Method: SOLUTION NMR Cite: Capturing the catalytic intermediates of parkin ubiquitination. Proc.Natl.Acad.Sci.USA, 121, 2024
9BOL	Crystal structure of the complex between VHL, ElonginB, ElonginC, and compound 5 Descriptor: (4R)-1-[(2S)-2-(4-cyclopropyl-1H-1,2,3-triazol-1-yl)-3,3-dimethylbutanoyl]-4-hydroxy-N-{[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl}-L-prolinamide, 1,2-ETHANEDIOL, CHLORIDE ION, ... Authors: Murray, J.M, Wu, H, Fuhrmann, J, Fairbrother, W.J, DiPasquale, A. Deposit date: 2024-05-03 Release date: 2024-05-29 Method: X-RAY DIFFRACTION (1.99 Å) Cite: Potency-enhanced peptidomimetic VHL ligands with improved oral bioavailability To Be Published
9BJU	Crystal structure of the complex between VHL, ElonginB, ElonginC, and compound 5 Descriptor: 1,2-ETHANEDIOL, 3-PYRIDIN-4-YL-2,4-DIHYDRO-INDENO[1,2-.C.]PYRAZOLE, ACETATE ION, ... Authors: Murray, J.M, Wu, H, Fuhrmann, J, Fairbrother, W.J, DiPasquale, A. Deposit date: 2024-04-25 Release date: 2024-05-29 Method: X-RAY DIFFRACTION (2.47 Å) Cite: Potency-enhanced peptidomimetic VHL ligands with improved oral bioavailability To Be Published
9F1D	Mammalian quaternary complex of a translating 80S ribosome, NAC, MetAP1 and NatA/E-HYPK Descriptor: 18S rRNA, 28S rRNA, 40S ribosomal protein S11, ... Authors: Yudin, D, Scaiola, A, Ban, N. Deposit date: 2024-04-18 Release date: 2024-08-21 Last modified: 2024-09-11 Method: ELECTRON MICROSCOPY (3.26 Å) Cite: NAC guides a ribosomal multienzyme complex for nascent protein processing. Nature, 2024
9F1B	Mammalian ternary complex of a translating 80S ribosome, NAC and NatA/E Descriptor: 18S rRNA, 28S rRNA, 40S ribosomal protein S11, ... Authors: Yudin, D, Scaiola, A, Ban, N. Deposit date: 2024-04-18 Release date: 2024-08-21 Last modified: 2024-09-11 Method: ELECTRON MICROSCOPY (3.01 Å) Cite: NAC guides a ribosomal multienzyme complex for nascent protein processing. Nature, 2024
9F1C	Mammalian quaternary complex of a translating 80S ribosome, NAC, MetAP1 and NatA/E Descriptor: 18S rRNA, 28S rRNA, 40S ribosomal protein S11, ... Authors: Yudin, D, Scaiola, A, Ban, N. Deposit date: 2024-04-18 Release date: 2024-08-21 Last modified: 2024-09-11 Method: ELECTRON MICROSCOPY (3.78 Å) Cite: NAC guides a ribosomal multienzyme complex for nascent protein processing. Nature, 2024
9B5B	Ubiquitin E2-Ub-E3 HECT tetrahedral transthiolation intermediate mimic - state 7 Descriptor: 4-aminobutanenitrile, E3 ubiquitin-protein ligase pub2, Ubiquitin, ... Authors: Kochanczyk, T, Lima, C.D. Deposit date: 2024-03-22 Release date: 2024-06-05 Last modified: 2024-09-11 Method: ELECTRON MICROSCOPY (3.31 Å) Cite: Structural basis for transthiolation intermediates in the ubiquitin pathway. Nature, 633, 2024
9B5M	Ubiquitin E1-Ub-E2 tetrahedral transthiolation intermediate mimic (singly Ub-loaded) - consensus map and model Descriptor: 4-aminobutanenitrile, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... Authors: Kochanczyk, T, Lima, C.D. Deposit date: 2024-03-22 Release date: 2024-06-05 Last modified: 2024-09-04 Method: ELECTRON MICROSCOPY (2.79 Å) Cite: Structural basis for transthiolation intermediates in the ubiquitin pathway. Nature, 2024
9B55	Ubiquitin E2-Ub-E3 HECT tetrahedral transthiolation intermediate mimic - state 1 Descriptor: 4-aminobutanenitrile, E3 ubiquitin-protein ligase pub2, Ubiquitin, ... Authors: Kochanczyk, T, Lima, C.D. Deposit date: 2024-03-22 Release date: 2024-06-05 Last modified: 2024-09-11 Method: ELECTRON MICROSCOPY (3.23 Å) Cite: Structural basis for transthiolation intermediates in the ubiquitin pathway. Nature, 633, 2024
9B5F	Ubiquitin E1-Ub-E2 tetrahedral transthiolation intermediate mimic (doubly Ub-loaded) - cluster 1 map and model (Ub(A)/ATP/Mg) Descriptor: 4-aminobutanenitrile, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... Authors: Kochanczyk, T, Lima, C.D. Deposit date: 2024-03-22 Release date: 2024-06-05 Last modified: 2024-08-28 Method: ELECTRON MICROSCOPY (2.78 Å) Cite: Structural basis for transthiolation intermediates in the ubiquitin pathway. Nature, 2024
9B5S	Ubiquitin E1-Ub-E2 tetrahedral transthiolation intermediate mimic (singly Ub-loaded) - cluster 4 map and model (ATP/Mg) Descriptor: 4-aminobutanenitrile, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... Authors: Kochanczyk, T, Lima, C.D. Deposit date: 2024-03-22 Release date: 2024-06-05 Last modified: 2024-09-04 Method: ELECTRON MICROSCOPY (2.96 Å) Cite: Structural basis for transthiolation intermediates in the ubiquitin pathway. Nature, 2024
9B5C	Ubiquitin E1-Ub-E2 tetrahedral transthiolation intermediate mimic (doubly Ub-loaded) - consensus map and model Descriptor: 4-aminobutanenitrile, ADENOSINE-5'-TRIPHOSPHATE, Large ribosomal subunit protein eL40B, ... Authors: Kochanczyk, T, Lima, C.D. Deposit date: 2024-03-22 Release date: 2024-06-05 Last modified: 2024-08-28 Method: ELECTRON MICROSCOPY (2.5 Å) Cite: Structural basis for transthiolation intermediates in the ubiquitin pathway. Nature, 2024
9B5Q	Ubiquitin E1-Ub-E2 tetrahedral transthiolation intermediate mimic (singly Ub-loaded) - cluster 2 map and model (ATP/Mg) Descriptor: 4-aminobutanenitrile, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... Authors: Kochanczyk, T, Lima, C.D. Deposit date: 2024-03-22 Release date: 2024-06-05 Last modified: 2024-09-04 Method: ELECTRON MICROSCOPY (2.95 Å) Cite: Structural basis for transthiolation intermediates in the ubiquitin pathway. Nature, 2024
9B5O	Ubiquitin E1-Ub-E2 tetrahedral transthiolation intermediate mimic (singly Ub-loaded) - Ub(T) class 10 map and model from consensus Descriptor: 4-aminobutanenitrile, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... Authors: Kochanczyk, T, Lima, C.D. Deposit date: 2024-03-22 Release date: 2024-06-05 Last modified: 2024-09-04 Method: ELECTRON MICROSCOPY (3.19 Å) Cite: Structural basis for transthiolation intermediates in the ubiquitin pathway. Nature, 2024
9B5N	Ubiquitin E1-Ub-E2 tetrahedral transthiolation intermediate mimic (singly Ub-loaded) - Ub(T) class 1 map and model from consensus Descriptor: 4-aminobutanenitrile, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... Authors: Kochanczyk, T, Lima, C.D. Deposit date: 2024-03-22 Release date: 2024-06-05 Last modified: 2024-09-04 Method: ELECTRON MICROSCOPY (3.12 Å) Cite: Structural basis for transthiolation intermediates in the ubiquitin pathway. Nature, 2024
9B5U	Ubiquitin E1-Ub-E2 tetrahedral transthiolation intermediate mimic (singly Ub-loaded) - Ub(T) class 1 map and model from cluster 1 (ATP/Mg) Descriptor: 4-aminobutanenitrile, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... Authors: Kochanczyk, T, Lima, C.D. Deposit date: 2024-03-22 Release date: 2024-06-05 Last modified: 2024-09-04 Method: ELECTRON MICROSCOPY (3.67 Å) Cite: Structural basis for transthiolation intermediates in the ubiquitin pathway. Nature, 2024
9B5A	Ubiquitin E2-Ub-E3 HECT tetrahedral transthiolation intermediate mimic - state 6 Descriptor: 4-aminobutanenitrile, E3 ubiquitin-protein ligase pub2, Ubiquitin, ... Authors: Kochanczyk, T, Lima, C.D. Deposit date: 2024-03-22 Release date: 2024-06-05 Last modified: 2024-09-11 Method: ELECTRON MICROSCOPY (3.65 Å) Cite: Structural basis for transthiolation intermediates in the ubiquitin pathway. Nature, 633, 2024
9B5L	Ubiquitin E1-Ub-E2 tetrahedral transthiolation intermediate mimic (doubly Ub-loaded) - Ub(T) class 10 map and model from cluster 5 (Ub(A)-AMP) Descriptor: 4-aminobutanenitrile, ADENOSINE MONOPHOSPHATE, Polyubiquitin, ... Authors: Kochanczyk, T, Lima, C.D. Deposit date: 2024-03-22 Release date: 2024-06-05 Last modified: 2024-08-28 Method: ELECTRON MICROSCOPY (3.3 Å) Cite: Structural basis for transthiolation intermediates in the ubiquitin pathway. Nature, 2024
9B59	Ubiquitin E2-Ub-E3 HECT tetrahedral transthiolation intermediate mimic - state 5 Descriptor: 4-aminobutanenitrile, E3 ubiquitin-protein ligase pub2, Ubiquitin, ... Authors: Kochanczyk, T, Lima, C.D. Deposit date: 2024-03-22 Release date: 2024-06-05 Last modified: 2024-09-11 Method: ELECTRON MICROSCOPY (3.49 Å) Cite: Structural basis for transthiolation intermediates in the ubiquitin pathway. Nature, 633, 2024
9B5X	Ubiquitin E1-Ub-E2 tetrahedral transthiolation intermediate mimic (singly Ub-loaded) - Ub(T) class 10 map and model from cluster 5 (ATP/Mg) Descriptor: 4-aminobutanenitrile, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... Authors: Kochanczyk, T, Lima, C.D. Deposit date: 2024-03-22 Release date: 2024-06-05 Last modified: 2024-09-04 Method: ELECTRON MICROSCOPY (4.16 Å) Cite: Structural basis for transthiolation intermediates in the ubiquitin pathway. Nature, 2024
9B5H	Ubiquitin E1-Ub-E2 tetrahedral transthiolation intermediate mimic (doubly Ub-loaded) - cluster 3 map and model (Ub(A)-AMP/PPi/Mg) Descriptor: 4-aminobutanenitrile, ADENOSINE MONOPHOSPHATE, Large ribosomal subunit protein eL40B, ... Authors: Kochanczyk, T, Lima, C.D. Deposit date: 2024-03-22 Release date: 2024-06-05 Last modified: 2024-08-28 Method: ELECTRON MICROSCOPY (2.69 Å) Cite: Structural basis for transthiolation intermediates in the ubiquitin pathway. Nature, 2024
9B5V	Ubiquitin E1-Ub-E2 tetrahedral transthiolation intermediate mimic (singly Ub-loaded) - Ub(T) class 10 map and model from cluster 1 (ATP/Mg) Descriptor: 4-aminobutanenitrile, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... Authors: Kochanczyk, T, Lima, C.D. Deposit date: 2024-03-22 Release date: 2024-06-05 Last modified: 2024-09-04 Method: ELECTRON MICROSCOPY (3.94 Å) Cite: Structural basis for transthiolation intermediates in the ubiquitin pathway. Nature, 2024
9B5G	Ubiquitin E1-Ub-E2 tetrahedral transthiolation intermediate mimic (doubly Ub-loaded) - cluster 2 map and model (Ub(A)/ATP/Mg) Descriptor: 4-aminobutanenitrile, ADENOSINE-5'-TRIPHOSPHATE, Large ribosomal subunit protein eL40B, ... Authors: Kochanczyk, T, Lima, C.D. Deposit date: 2024-03-22 Release date: 2024-06-05 Last modified: 2024-08-28 Method: ELECTRON MICROSCOPY (2.67 Å) Cite: Structural basis for transthiolation intermediates in the ubiquitin pathway. Nature, 2024
9B5W	Ubiquitin E1-Ub-E2 tetrahedral transthiolation intermediate mimic (singly Ub-loaded) - Ub(T) class 1 map and model from cluster 5 (ATP/Mg) Descriptor: 4-aminobutanenitrile, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... Authors: Kochanczyk, T, Lima, C.D. Deposit date: 2024-03-22 Release date: 2024-06-05 Last modified: 2024-09-04 Method: ELECTRON MICROSCOPY (3.96 Å) Cite: Structural basis for transthiolation intermediates in the ubiquitin pathway. Nature, 2024
9B56	Ubiquitin E2-Ub-E3 HECT tetrahedral transthiolation intermediate mimic - state 2 Descriptor: 4-aminobutanenitrile, E3 ubiquitin-protein ligase pub2, Ubiquitin, ... Authors: Kochanczyk, T, Lima, C.D. Deposit date: 2024-03-22 Release date: 2024-06-05 Last modified: 2024-09-11 Method: ELECTRON MICROSCOPY (3.35 Å) Cite: Structural basis for transthiolation intermediates in the ubiquitin pathway. Nature, 633, 2024

 

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