PDB: 224004 resultsInfo pagesStatus searchChemie searchBIRD

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2QSH	Crystal structure of Rad4-Rad23 bound to a mismatch DNA Descriptor: DNA repair protein RAD4, UV excision repair protein RAD23, bottom strand of the mismatch DNA, ... Authors: Min, J.-H, Pavletich, N.P. Deposit date: 2007-07-31 Release date: 2007-10-02 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2.805 Å) Cite: Recognition of DNA damage by the Rad4 nucleotide excision repair protein Nature, 449, 2007
2QUS	Hammerhead Ribozyme G12A mutant pre-cleavage Descriptor: Hammerhead ribozyme, MAGNESIUM ION Authors: Chi, Y.I, Scott, W.G, Kim, S.H. Deposit date: 2007-08-06 Release date: 2008-07-15 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Capturing hammerhead ribozyme structures in action by modulating general base catalysis. Plos Biol., 6, 2008
2QB5	Crystal Structure of Human Inositol 1,3,4-Trisphosphate 5/6-Kinase (ITPK1) in Complex with ADP and Mn2+ Descriptor: ADENOSINE-5'-DIPHOSPHATE, Inositol-tetrakisphosphate 1-kinase, MANGANESE (II) ION, ... Authors: Chamberlain, P.P, Lesley, S.A, Spraggon, G. Deposit date: 2007-06-15 Release date: 2007-07-03 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Integration of inositol phosphate signaling pathways via human ITPK1. J.Biol.Chem., 282, 2007
2QKU	The 5th PDZ Domain of InaD in 10mM DTT Descriptor: GLYCEROL, Inactivation-no-after-potential D protein Authors: Ranganathan, R, Socolich, M, Wall, M. Deposit date: 2007-07-11 Release date: 2007-11-06 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Dynamic Scaffolding in a G Protein-Coupled Signaling System. Cell(Cambridge,Mass.), 131, 2007
2QP4	Identification and Characterization of Two Amino Acids Critical for the Substrate Inhibition of SULT2A1 Descriptor: (3Beta,5alpha)-3-Hydroxyandrostan-17-one, Bile salt sulfotransferase Authors: Hsieh, Y.C. Deposit date: 2007-07-23 Release date: 2008-07-29 Last modified: 2024-05-29 Method: X-RAY DIFFRACTION (3 Å) Cite: Identification and characterization of two amino acids critical for the substrate inhibition of human dehydroepiandrosterone sulfotransferase (SULT2A1) Mol.Pharmacol., 73, 2008
2QTC	E. coli Pyruvate dehydrogenase E1 component E401K mutant with phosphonolactylthiamin diphosphate Descriptor: 3-[(4-AMINO-2-METHYLPYRIMIDIN-5-YL)METHYL]-2-{(1S)-1-HYDROXY-1-[(R)-HYDROXY(METHOXY)PHOSPHORYL]ETHYL}-5-(2-{[(S)-HYDROXY(PHOSPHONOOXY)PHOSPHORYL]OXY}ETHYL)-4-METHYL-1,3-THIAZOL-3-IUM, MAGNESIUM ION, Pyruvate dehydrogenase E1 component Authors: Furey, W, Arjunan, P, Chandrasekhar, K. Deposit date: 2007-08-01 Release date: 2007-08-14 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (1.77 Å) Cite: A Dynamic Loop at the Active Center of the Escherichia coli Pyruvate Dehydrogenase Complex E1 Component Modulates Substrate Utilization and Chemical Communication with the E2 Component J.Biol.Chem., 282, 2007
2QVW	Structure of Giardia Dicer refined against twinned data Descriptor: GLP_546_48378_50642, MANGANESE (II) ION Authors: Doudna, J.A, MacRae, I.J. Deposit date: 2007-08-09 Release date: 2007-09-25 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (3 Å) Cite: An unusual case of pseudo-merohedral twinning in orthorhombic crystals of Dicer Acta Crystallogr.,Sect.D, 63, 2007
1VSU	Crystal Structure of Apo-glyceraldehyde 3-phosphate dehydrogenase from Cryptosporidium parvum Descriptor: Glyceraldehyde-3-phosphate dehydrogenase Authors: Cook, W.J, Senkovich, O, Chattopadhyay, D. Deposit date: 2008-03-10 Release date: 2009-03-24 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (2.2 Å) Cite: An unexpected phosphate binding site in Glyceraldehyde 3-Phosphate Dehydrogenase: Crystal structures of apo, holo and ternary complex of Cryptosporidium parvum enzyme BMC STRUCT.BIOL., 9, 2009
1VVJ	Crystal Structure of Frameshift Suppressor tRNA SufA6 bound to Codon CCC-G on the Ribosome Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... Authors: Maehigashi, T, Dunkle, J.A, Dunham, C.M. Deposit date: 2013-05-24 Release date: 2014-08-06 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (3.440001 Å) Cite: Structural insights into +1 frameshifting promoted by expanded or modification-deficient anticodon stem loops. Proc.Natl.Acad.Sci.USA, 111, 2014
2R26	The Structure of the Ternary Complex of Carboxymethyl Coenzyme A and Oxalateacetate with Citrate Synthase from the Thermophilic Archaeonthermoplasma Acidophilum Descriptor: CARBOXYMETHYL COENZYME *A, Citrate Synthase, OXALOACETATE ION Authors: Lehmann, C. Deposit date: 2007-08-24 Release date: 2008-08-12 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.5 Å) Cite: The Structure of the Ternary Complex of Carboxymethyl Coenzyme A and Oxalateacetate with Citrate Synthase from the Thermophilic Archaeonthermoplasma Acidophilum To be Published, 2007
2R3P	Crystal Structure of Cyclin-Dependent Kinase 2 with inhibitor Descriptor: 5-(2,3-dichlorophenyl)-N-(pyridin-4-ylmethyl)-3-thiocyanatopyrazolo[1,5-a]pyrimidin-7-amine, Cell division protein kinase 2 Authors: Fischmann, T.O, Hruza, A.W, Madison, V.M, Duca, J.S. Deposit date: 2007-08-29 Release date: 2008-01-22 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (1.66 Å) Cite: Structure-guided discovery of cyclin-dependent kinase inhibitors. Biopolymers, 89, 2008
2R22	Structure of the native RNA tridecamer r(GCGUUUGAAACGC) at 1.5 A (NatMn) Descriptor: MANGANESE (II) ION, RNA (5'-R(*GP*CP*GP*UP*UP*UP*GP*AP*AP*AP*CP*GP*C)-3'), SODIUM ION Authors: Timsit, Y, Bombard, S. Deposit date: 2007-08-24 Release date: 2007-09-25 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (1.4 Å) Cite: The 1.3 A structure of the tridecamer r(GCGUUUGAAACGC) TO BE PUBLISHED
2R3K	Crystal Structure of Cyclin-Dependent Kinase 2 with inhibitor Descriptor: 3-bromo-5-phenyl-N-(pyrimidin-5-ylmethyl)pyrazolo[1,5-a]pyridin-7-amine, Cell division protein kinase 2 Authors: Fischmann, T.O, Hruza, A.W, Madison, V.M, Duca, J.S. Deposit date: 2007-08-29 Release date: 2008-01-22 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Structure-guided discovery of cyclin-dependent kinase inhibitors. Biopolymers, 89, 2008
2R4F	Substituted Pyrazoles as Hepatselective HMG-COA reductase inhibitors Descriptor: (3R,5R)-7-[1-(4-fluorophenyl)-4-(1-methylethyl)-3-{methyl[(1R)-1-phenylethyl]carbamoyl}-1H-pyrazol-5-yl]-3,5-dihydroxyheptanoic acid, 3-hydroxy-3-methylglutaryl-coenzyme A reductase, SULFATE ION Authors: Pavlovsky, A, Pfefferkorn, J.A, Harris, M.S, Finzel, B.C. Deposit date: 2007-08-31 Release date: 2008-04-29 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Substituted pyrazoles as hepatoselective HMG-CoA reductase inhibitors: discovery of (3R,5R)-7-[2-(4-fluoro-phenyl)-4-isopropyl-5-(4-methyl-benzylcarbamoyl)-2H-pyrazol-3-yl]-3,5-dihydroxyheptanoic acid (PF-3052334) as a candidate for the treatment of hypercholesterolemia. J.Med.Chem., 51, 2008
2QFT	E.coli EPSP synthase Pro101Ser liganded with S3P and glyphosate Descriptor: 3-phosphoshikimate 1-carboxyvinyltransferase, FORMIC ACID, GLYPHOSATE, ... Authors: Schonbrunn, E, Healy-Fried, M.L. Deposit date: 2007-06-28 Release date: 2007-10-02 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (1.55 Å) Cite: Structural basis of glyphosate tolerance resulting from mutations of Pro101 in Escherichia coli 5-enolpyruvylshikimate-3-phosphate synthase. J.Biol.Chem., 282, 2007
2QA5	Crystal structure of Sept2 G-domain Descriptor: GUANOSINE-5'-DIPHOSPHATE, Septin-2 Authors: Sirajuddin, M, Wittinghofer, A. Deposit date: 2007-06-14 Release date: 2007-08-07 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (3.4 Å) Cite: Structural insight into filament formation by mammalian septins. Nature, 449, 2007
2QSG	Crystal structure of Rad4-Rad23 bound to a UV-damaged DNA Descriptor: DNA repair protein RAD4, UV excision repair protein RAD23, damaged strand of the CPD-mismatch DNA, ... Authors: Min, J.-H, Pavletich, N.P. Deposit date: 2007-07-31 Release date: 2007-10-02 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (3.1 Å) Cite: Recognition of DNA damage by the Rad4 nucleotide excision repair protein Nature, 449, 2007
2R0Q	Crystal structure of a serine recombinase- DNA regulatory complex Descriptor: 31-MER, Putative transposon Tn552 DNA-invertase bin3, SULFATE ION Authors: Rice, P.A, Mouw, K.W. Deposit date: 2007-08-21 Release date: 2008-04-01 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (3.2 Å) Cite: Architecture of a serine recombinase-DNA regulatory complex. Mol.Cell, 30, 2008
2QYI	Crystal structure of a binary complex between an engineered trypsin inhibitor and Bovine trypsin Descriptor: CALCIUM ION, Cationic trypsin, Chymotrypsin inhibitor 3, ... Authors: Khamrui, S, Dasgupta, J, Dattagupta, J.K, Sen, U. Deposit date: 2007-08-15 Release date: 2008-08-19 Last modified: 2021-11-10 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Crystal structure of a binary complex between an engineered trypsin inhibitor and Bovine trypsin To be Published
2R3D	Ricin A-chain (recombinant) complex with Acetamide Descriptor: ACETAMIDE, Ricin A chain (EC 3.2.2.22), SULFATE ION Authors: Carra, J.H, McHugh, C.A, Mulligan, S, Machiesky, L.M, Soares, A.S, Millard, C.B. Deposit date: 2007-08-29 Release date: 2007-11-20 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2.09 Å) Cite: Fragment-based identification of determinants of conformational and spectroscopic change at the ricin active site BMC Struct.Biol., 7, 2007
2R3N	Crystal Structure of Cyclin-Dependent Kinase 2 with inhibitor Descriptor: 3-cyclopropyl-5-phenyl-N-(pyridin-3-ylmethyl)pyrazolo[1,5-a]pyrimidin-7-amine, Cell division protein kinase 2 Authors: Fischmann, T.O, Hruza, A.W, Madison, V.M, Duca, J.S. Deposit date: 2007-08-29 Release date: 2008-01-22 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (1.63 Å) Cite: Structure-guided discovery of cyclin-dependent kinase inhibitors. Biopolymers, 89, 2008
2R1H	met-Trout IV hemoglobin at pH 6.3 Descriptor: 1,2-ETHANEDIOL, Hemoglobin subunit alpha-4, Hemoglobin subunit beta-4, ... Authors: Aranda IV, R, Worley, C.E, Richards, M.P, Phillips Jr, G.N. Deposit date: 2007-08-22 Release date: 2008-09-02 Last modified: 2013-01-30 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Structural analysis of fish versus mammalian hemoglobins: Effect of the heme pocket environment on autooxidation and hemin loss. Proteins, 75, 2008
2Q9T	High-resolution structure of the DING protein from Pseudomonas fluorescens Descriptor: 1,2-ETHANEDIOL, ACETATE ION, DING, ... Authors: Moniot, S, Ahn, S, Elias, M, Kim, D, Scott, K, Chabriere, E. Deposit date: 2007-06-14 Release date: 2008-06-17 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (1.43 Å) Cite: Structure-function relationships in a bacterial DING protein. Febs Lett., 581, 2007
2QBL	Crystal structure of ferric G248T cytochrome P450cam Descriptor: CAMPHOR, Cytochrome P450-cam, POTASSIUM ION, ... Authors: von Koenig, K, Makris, T.M, Sligar, S.D, Schlichting, I. Deposit date: 2007-06-18 Release date: 2007-12-25 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Alteration of P450 Distal Pocket Solvent Leads to Impaired Proton Delivery and Changes in Heme Geometry. Biochemistry, 46, 2007
2QBN	Crystal structure of ferric G248V cytochrome P450cam Descriptor: CAMPHOR, Cytochrome P450-cam, POTASSIUM ION, ... Authors: von Koenig, K, Makris, T.M, Sligar, S.D, Schlichting, I. Deposit date: 2007-06-18 Release date: 2007-12-25 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (1.75 Å) Cite: Alteration of P450 Distal Pocket Solvent Leads to Impaired Proton Delivery and Changes in Heme Geometry. Biochemistry, 46, 2007

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