2QB5

Crystal Structure of Human Inositol 1,3,4-Trisphosphate 5/6-Kinase (ITPK1) in Complex with ADP and Mn2+

Summary for 2QB5

Entry DOI	10.2210/pdb2qb5/pdb
Descriptor	Inositol-tetrakisphosphate 1-kinase, SULFATE ION, MANGANESE (II) ION, ... (5 entities in total)
Functional Keywords	inositol, inositol kinase, kinase, itpk1, inositol 1, 3, 4-5/6-kinase, phosphate, inositol phosphate, inositolphosphate, polyphosphate, transferase
Biological source	Homo sapiens (human)
Total number of polymer chains	2
Total formula weight	80552.00
Authors	Chamberlain, P.P.,Lesley, S.A.,Spraggon, G. (deposition date: 2007-06-15, release date: 2007-07-03, Last modification date: 2024-02-21)
Primary citation	Chamberlain, P.P.,Qian, X.,Stiles, A.R.,Cho, J.,Jones, D.H.,Lesley, S.A.,Grabau, E.A.,Shears, S.B.,Spraggon, G. Integration of inositol phosphate signaling pathways via human ITPK1. J.Biol.Chem., 282:28117-28125, 2007 Cited by PubMed: 17616525 DOI: 10.1074/jbc.M703121200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.8 Å)

Structure validation