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8IQK
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Structural basis of the specificity and interaction mechanism of Bmf binding to pro-survival proteins
Descriptor: Bcl-2-like protein 1, Bcl-2-modifying factor
Authors:Wang, H, Guo, M, Wei, H, Chen, Y.
Deposit date:2023-03-16
Release date:2023-08-23
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.879 Å)
Cite:Structural basis of the specificity and interaction mechanism of Bmf binding to pro-survival Bcl-2 family proteins.
Comput Struct Biotechnol J, 21, 2023
8IQL
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Structural basis of the specificity and interaction mechanism of Bmf binding to pro-survival proteins
Descriptor: Apoptosis regulator Bcl-2, Bcl-2-modifying factor
Authors:Wang, H, Guo, M, Wei, H, Chen, Y.
Deposit date:2023-03-16
Release date:2023-08-23
Method:X-RAY DIFFRACTION (2.9577 Å)
Cite:Structural basis of the specificity and interaction mechanism of Bmf binding to pro-survival Bcl-2 family proteins.
Comput Struct Biotechnol J, 21, 2023
1GTA
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BU of 1gta by Molmil
CRYSTAL STRUCTURES OF A SCHISTOSOMAL DRUG AND VACCINE TARGET: GLUTATHIONE S-TRANSFERASE FROM SCHISTOSOMA JAPONICA AND ITS COMPLEX WITH THE LEADING ANTISCHISTOSOMAL DRUG PRAZIQUANTEL
Descriptor: GLUTATHIONE S-TRANSFERASE
Authors:Mctigue, M.A, Tainer, J.A.
Deposit date:1994-12-01
Release date:1995-02-07
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structures of a schistosomal drug and vaccine target: glutathione S-transferase from Schistosoma japonica and its complex with the leading antischistosomal drug praziquantel.
J.Mol.Biol., 246, 1995
8IX0
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BU of 8ix0 by Molmil
Cryo-EM structure of unprotonated LHCII nanodisc at high pH value
Descriptor: (1R,3R)-6-{(3E,5E,7E,9E,11E,13E,15E,17E)-18-[(1S,4R,6R)-4-HYDROXY-2,2,6-TRIMETHYL-7-OXABICYCLO[4.1.0]HEPT-1-YL]-3,7,12,16-TETRAMETHYLOCTADECA-1,3,5,7,9,11,13,15,17-NONAENYLIDENE}-1,5,5-TRIMETHYLCYCLOHEXANE-1,3-DIOL, (3R,3'R,6S)-4,5-DIDEHYDRO-5,6-DIHYDRO-BETA,BETA-CAROTENE-3,3'-DIOL, (3S,5R,6S,3'S,5'R,6'S)-5,6,5',6'-DIEPOXY-5,6,5',6'- TETRAHYDRO-BETA,BETA-CAROTENE-3,3'-DIOL, ...
Authors:Ruan, M.X, Ding, W.
Deposit date:2023-03-31
Release date:2023-09-06
Last modified:2023-10-04
Method:ELECTRON MICROSCOPY (2.64 Å)
Cite:Cryo-EM structures of LHCII in photo-active and photo-protecting states reveal allosteric regulation of light harvesting and excess energy dissipation.
Nat.Plants, 9, 2023
8IX2
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BU of 8ix2 by Molmil
Cryo-EM structure of unprotonated LHCII nanodisc at low pH value
Descriptor: (1R,3R)-6-{(3E,5E,7E,9E,11E,13E,15E,17E)-18-[(1S,4R,6R)-4-HYDROXY-2,2,6-TRIMETHYL-7-OXABICYCLO[4.1.0]HEPT-1-YL]-3,7,12,16-TETRAMETHYLOCTADECA-1,3,5,7,9,11,13,15,17-NONAENYLIDENE}-1,5,5-TRIMETHYLCYCLOHEXANE-1,3-DIOL, (3R,3'R,6S)-4,5-DIDEHYDRO-5,6-DIHYDRO-BETA,BETA-CAROTENE-3,3'-DIOL, (3S,5R,6S,3'S,5'R,6'S)-5,6,5',6'-DIEPOXY-5,6,5',6'- TETRAHYDRO-BETA,BETA-CAROTENE-3,3'-DIOL, ...
Authors:Ruan, M.X, Ding, W.
Deposit date:2023-03-31
Release date:2023-09-06
Last modified:2023-10-04
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Cryo-EM structures of LHCII in photo-active and photo-protecting states reveal allosteric regulation of light harvesting and excess energy dissipation.
Nat.Plants, 9, 2023
1QXP
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BU of 1qxp by Molmil
Crystal Structure of a mu-like calpain
Descriptor: mu-like calpain
Authors:Pal, G.P, Veyra, T.D, Elce, J.S, Jia, Z.
Deposit date:2003-09-08
Release date:2004-02-03
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal Structure of a mu-like calpain reveals a partially activated conformation with low Ca(2+) requirement
Structure, 11, 2003
8IMX
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BU of 8imx by Molmil
Cryo-EM structure of GPI-T with a chimeric GPI-anchored protein
Descriptor: 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Xu, Y, Li, T, Qu, Q, Li, D.
Deposit date:2023-03-07
Release date:2023-08-16
Last modified:2024-10-16
Method:ELECTRON MICROSCOPY (2.85 Å)
Cite:Structures of liganded glycosylphosphatidylinositol transamidase illuminate GPI-AP biogenesis.
Nat Commun, 14, 2023
1GSU
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BU of 1gsu by Molmil
AN AVIAN CLASS-MU GLUTATHIONE S-TRANSFERASE, CGSTM1-1 AT 1.94 ANGSTROM RESOLUTION
Descriptor: CLASS-MU GLUTATHIONE S-TRANSFERASE, S-HEXYLGLUTATHIONE
Authors:Sun, Y.-J, Kuan, C, Tam, M.F, Hsiao, C.-D.
Deposit date:1997-09-02
Release date:1998-03-04
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:The three-dimensional structure of an avian class-mu glutathione S-transferase, cGSTM1-1 at 1.94 A resolution.
J.Mol.Biol., 278, 1998
1GTB
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BU of 1gtb by Molmil
CRYSTAL STRUCTURES OF A SCHISTOSOMAL DRUG AND VACCINE TARGET: GLUTATHIONE S-TRANSFERASE FROM SCHISTOSOMA JAPONICA AND ITS COMPLEX WITH THE LEADING ANTISCHISTOSOMAL DRUG PRAZIQUANTEL
Descriptor: GLUTATHIONE S-TRANSFERASE, PRAZIQUANTEL
Authors:Mctigue, M.A, Tainer, J.A.
Deposit date:1994-12-01
Release date:1995-12-01
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structures of a schistosomal drug and vaccine target: glutathione S-transferase from Schistosoma japonica and its complex with the leading antischistosomal drug praziquantel.
J.Mol.Biol., 246, 1995
1GYY
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BU of 1gyy by Molmil
The Crystal Structure of YdcE, a 4-Oxalocrotonate Tautomerase Homologue from Escherichia coli, Confirms the Structural Basis for Oligomer Diversity
Descriptor: 2-FLUORO-3-(4-HYDROXYPHENYL)-2E-PROPENEOATE, HYPOTHETICAL PROTEIN YDCE
Authors:Almrud, J, Kern, A, Wang, S, Czerwinski, R, Johnson, W, Murzin, A, Hackert, M, Whitman, C.
Deposit date:2002-04-30
Release date:2002-10-10
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:The Crystal Structure of Ydce, a 4-Oxalocrotonate Tautomerase Homologue from Escherichia Coli, Confirms the Structural Basis for Oligomer Diversity
Biochemistry, 41, 2002
8IMY
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BU of 8imy by Molmil
Cryo-EM structure of GPI-T (inactive mutant) with GPI and proULBP2, a proprotein substrate
Descriptor: 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Li, T, Xu, Y, Qu, Q, Li, D.
Deposit date:2023-03-07
Release date:2023-08-16
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (3.22 Å)
Cite:Structures of liganded glycosylphosphatidylinositol transamidase illuminate GPI-AP biogenesis.
Nat Commun, 14, 2023
1GYJ
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BU of 1gyj by Molmil
The Crystal Structure of YdcE, a 4-Oxalocrotonate Tautomerase Homologue from Escherichia coli, Confirms the Structural Basis for Oligomer Diversity
Descriptor: HYPOTHETICAL PROTEIN YDCE
Authors:Almrud, J, Kern, A, Wang, S, Czerwinski, R, Johnson, W, Murzin, A, Hackert, M, Whitman, C.
Deposit date:2002-04-23
Release date:2002-10-10
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The Crystal Structure of Ydce, a 4-Oxalocrotonate Tautomerase Homologue from Escherichia Coli, Confirms the Structural Basis for Oligomer Diversity
Biochemistry, 41, 2002
1QD6
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BU of 1qd6 by Molmil
OUTER MEMBRANE PHOSPHOLIPASE A FROM ESCHERICHIA COLI
Descriptor: 1-HEXADECANOSULFONIC ACID, CALCIUM ION, OUTER MEMBRANE PHOSPHOLIPASE (OMPLA), ...
Authors:Snijder, H.J, Ubarretxena-Belandia, I, Blaauw, M, Kalk, K.H, Verheij, H.M, Egmond, M.R, Dekker, N, Dijkstra, B.W.
Deposit date:1999-07-09
Release date:1999-10-25
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural evidence for dimerization-regulated activation of an integral membrane phospholipase.
Nature, 401, 1999
1QW6
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BU of 1qw6 by Molmil
Rat neuronal nitric oxide synthase oxygenase domain in complex with N-omega-propyl-L-Arg.
Descriptor: 5,6,7,8-TETRAHYDROBIOPTERIN, N-OMEGA-PROPYL-L-ARGININE, Nitric-oxide synthase, ...
Authors:Fedorov, R, Hartmann, E, Ghosh, D.K, Schlichting, I.
Deposit date:2003-09-01
Release date:2003-12-09
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural basis for the specificity of the nitric-oxide synthase inhibitors W1400 and Nomega-propyl-L-Arg for the inducible and neuronal isoforms.
J.Biol.Chem., 278, 2003
1H3A
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BU of 1h3a by Molmil
Structures of Human Oxidosqualene Cyclase Inhibitors Bound to an Homologous Enzyme
Descriptor: (2E)-N-ALLYL-4-{[3-(4-BROMOPHENYL)-5-FLUORO-1-METHYL-1H-INDAZOL-6-YL]OXY}-N-METHYL-2-BUTEN-1-AMINE, (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, SQUALENE--HOPENE CYCLASE
Authors:Lenhart, A, Reinert, D.J, Weihofen, W.A, Aebi, J.D, Dehmlow, H, Morand, O.H, Schulz, G.E.
Deposit date:2002-08-24
Release date:2003-08-21
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Binding Structures and Potencies of Oxidosqualene Cyclase Inhibitors with the Homologous Squalene-Hopene Cyclase
J.Med.Chem., 46, 2003
8IWX
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BU of 8iwx by Molmil
Cryo-EM structure of unprotonated LHCII in detergent solution at high pH value
Descriptor: (1R,3R)-6-{(3E,5E,7E,9E,11E,13E,15E,17E)-18-[(1S,4R,6R)-4-HYDROXY-2,2,6-TRIMETHYL-7-OXABICYCLO[4.1.0]HEPT-1-YL]-3,7,12,16-TETRAMETHYLOCTADECA-1,3,5,7,9,11,13,15,17-NONAENYLIDENE}-1,5,5-TRIMETHYLCYCLOHEXANE-1,3-DIOL, (3R,3'R,6S)-4,5-DIDEHYDRO-5,6-DIHYDRO-BETA,BETA-CAROTENE-3,3'-DIOL, (3S,5R,6S,3'S,5'R,6'S)-5,6,5',6'-DIEPOXY-5,6,5',6'- TETRAHYDRO-BETA,BETA-CAROTENE-3,3'-DIOL, ...
Authors:Ruan, M.X, Ding, W.
Deposit date:2023-03-31
Release date:2023-09-06
Last modified:2023-10-04
Method:ELECTRON MICROSCOPY (2.59 Å)
Cite:Cryo-EM structures of LHCII in photo-active and photo-protecting states reveal allosteric regulation of light harvesting and excess energy dissipation.
Nat.Plants, 9, 2023
8IWY
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BU of 8iwy by Molmil
Cryo-EM structure of protonated LHCII in detergent solution at low pH value
Descriptor: (1R,3R)-6-{(3E,5E,7E,9E,11E,13E,15E,17E)-18-[(1S,4R,6R)-4-HYDROXY-2,2,6-TRIMETHYL-7-OXABICYCLO[4.1.0]HEPT-1-YL]-3,7,12,16-TETRAMETHYLOCTADECA-1,3,5,7,9,11,13,15,17-NONAENYLIDENE}-1,5,5-TRIMETHYLCYCLOHEXANE-1,3-DIOL, (3R,3'R,6S)-4,5-DIDEHYDRO-5,6-DIHYDRO-BETA,BETA-CAROTENE-3,3'-DIOL, (3S,5R,6S,3'S,5'R,6'S)-5,6,5',6'-DIEPOXY-5,6,5',6'- TETRAHYDRO-BETA,BETA-CAROTENE-3,3'-DIOL, ...
Authors:Ruan, M.X, Ding, W.
Deposit date:2023-03-31
Release date:2023-09-06
Last modified:2023-10-04
Method:ELECTRON MICROSCOPY (2.68 Å)
Cite:Cryo-EM structures of LHCII in photo-active and photo-protecting states reveal allosteric regulation of light harvesting and excess energy dissipation.
Nat.Plants, 9, 2023
1H3C
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BU of 1h3c by Molmil
Structures of Human Oxidosqualene Cyclase Inhibitors Bound to an Homologous Enzyme
Descriptor: (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, N-(6-{[3-(4-BROMOPHENYL)-1,2-BENZISOTHIAZOL-6-YL]OXY}HEXYL)-N-METHYLPROP-2-EN-1-AMINE, SQUALENE--HOPENE CYCLASE
Authors:Lenhart, A, Reinert, D.J, Weihofen, W.A, Aebi, J.D, Dehmlow, H, Morand, O.H, Schulz, G.E.
Deposit date:2002-08-25
Release date:2003-08-21
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Binding Structures and Potencies of Oxidosqualene Cyclase Inhibitors with the Homologous Squalene-Hopene Cyclase
J.Med.Chem., 46, 2003
1QXD
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BU of 1qxd by Molmil
Structural Basis for the Potent Antisickling Effect of a Novel Class of 5-Membered Heterocyclic Aldehydic Compounds
Descriptor: FURFURAL, Hemoglobin alpha chain, Hemoglobin beta chain, ...
Authors:Safo, M.K, Abdulmalik, O, Danso-Danquah, R, Nokuri, S, Joshi, G.S, Musayev, F.N, Asakura, T, Abraham, D.J.
Deposit date:2003-09-05
Release date:2003-09-16
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structural basis for the potent antisickling effect of a novel class of five-membered heterocyclic aldehydic compounds
J.Med.Chem., 47, 2004
1GSZ
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BU of 1gsz by Molmil
Crystal Structure of a Squalene Cyclase in Complex with the Potential Anticholesteremic Drug Ro48-8071
Descriptor: (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, SQUALENE--HOPENE CYCLASE, [4-({6-[ALLYL(METHYL)AMINO]HEXYL}OXY)-2-FLUOROPHENYL](4-BROMOPHENYL)METHANONE
Authors:Lenhart, A, Weihofen, W.A, Pleschke, A.E.W, Schulz, G.E.
Deposit date:2002-01-09
Release date:2003-01-16
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal Structure of a Squalene Cyclase in Complex with the Potential Anticholesteremic Drug Ro48-8071
Chem.Biol., 9, 2002
8J7X
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BU of 8j7x by Molmil
Cryo-EM structure of hZnT7DeltaHis-loop-Fab complex in zinc-unbound state, determined in outward-facing conformation
Descriptor: Heavy chain of YN7114-08 Fab, Light chain of YN7114-08 Fab, Zinc transporter 7
Authors:Han, B.B, Inaba, K, Watanabe, S.
Deposit date:2023-04-28
Release date:2023-09-20
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Cryo-EM structures of human zinc transporter ZnT7 reveal the mechanism of Zn 2+ uptake into the Golgi apparatus.
Nat Commun, 14, 2023
1H35
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BU of 1h35 by Molmil
Structures of Human Oxidosqualene Cyclase Inhibitors Bound to an Homologous Enzyme
Descriptor: (4'-{[ALLYL(METHYL)AMINO]METHYL}-1,1'-BIPHENYL-4-YL)(4-BROMOPHENYL)METHANONE, (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, SQUALENE--HOPENE CYCLASE
Authors:Lenhart, A, Reinert, D.J, Weihofen, W.A, Aebi, J.D, Dehmlow, H, Morand, O.H, Schulz, G.E.
Deposit date:2002-08-24
Release date:2003-08-21
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Binding Structures and Potencies of Oxidosqualene Cyclase Inhibitors with the Homologous Squalene-Hopene Cyclase
J.Med.Chem., 46, 2003
8IWZ
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BU of 8iwz by Molmil
Cryo-EM structure of unprotonated LHCII in detergent solution at low pH value
Descriptor: (1R,3R)-6-{(3E,5E,7E,9E,11E,13E,15E,17E)-18-[(1S,4R,6R)-4-HYDROXY-2,2,6-TRIMETHYL-7-OXABICYCLO[4.1.0]HEPT-1-YL]-3,7,12,16-TETRAMETHYLOCTADECA-1,3,5,7,9,11,13,15,17-NONAENYLIDENE}-1,5,5-TRIMETHYLCYCLOHEXANE-1,3-DIOL, (3R,3'R,6S)-4,5-DIDEHYDRO-5,6-DIHYDRO-BETA,BETA-CAROTENE-3,3'-DIOL, (3S,5R,6S,3'S,5'R,6'S)-5,6,5',6'-DIEPOXY-5,6,5',6'- TETRAHYDRO-BETA,BETA-CAROTENE-3,3'-DIOL, ...
Authors:Ruan, M.X, Ding, W.
Deposit date:2023-03-31
Release date:2023-09-06
Last modified:2023-10-04
Method:ELECTRON MICROSCOPY (2.52 Å)
Cite:Cryo-EM structures of LHCII in photo-active and photo-protecting states reveal allosteric regulation of light harvesting and excess energy dissipation.
Nat.Plants, 9, 2023
8IX1
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BU of 8ix1 by Molmil
Cryo-EM structure of protonated LHCII nanodisc at low pH value
Descriptor: (1R,3R)-6-{(3E,5E,7E,9E,11E,13E,15E,17E)-18-[(1S,4R,6R)-4-HYDROXY-2,2,6-TRIMETHYL-7-OXABICYCLO[4.1.0]HEPT-1-YL]-3,7,12,16-TETRAMETHYLOCTADECA-1,3,5,7,9,11,13,15,17-NONAENYLIDENE}-1,5,5-TRIMETHYLCYCLOHEXANE-1,3-DIOL, (3R,3'R,6S)-4,5-DIDEHYDRO-5,6-DIHYDRO-BETA,BETA-CAROTENE-3,3'-DIOL, (3S,5R,6S,3'S,5'R,6'S)-5,6,5',6'-DIEPOXY-5,6,5',6'- TETRAHYDRO-BETA,BETA-CAROTENE-3,3'-DIOL, ...
Authors:Ruan, M.X, Ding, W.
Deposit date:2023-03-31
Release date:2023-09-06
Last modified:2023-10-04
Method:ELECTRON MICROSCOPY (2.63 Å)
Cite:Cryo-EM structures of LHCII in photo-active and photo-protecting states reveal allosteric regulation of light harvesting and excess energy dissipation.
Nat.Plants, 9, 2023
8J7V
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BU of 8j7v by Molmil
Cryo-EM structure of hZnT7-Fab complex in zinc-unbound state, determined in heterogeneous conformations- one subunit in an inward-facing and the other in an outward-facing conformation
Descriptor: Heavy chain of YN7114-08 Fab, Light chain of YN7114-08 Fab, Zinc transporter 7
Authors:Han, B.B, Inaba, K, Watanabe, S.
Deposit date:2023-04-28
Release date:2023-09-20
Last modified:2024-10-16
Method:ELECTRON MICROSCOPY (2.79 Å)
Cite:Cryo-EM structures of human zinc transporter ZnT7 reveal the mechanism of Zn 2+ uptake into the Golgi apparatus.
Nat Commun, 14, 2023

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數據於2024-11-13公開中

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