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6PZA
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BU of 6pza by Molmil
Cryo-EM structure of the pancreatic beta-cell SUR1 bound to ATP and glibenclamide
Descriptor: 5-chloro-N-(2-{4-[(cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-2-methoxybenzamide, ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 8, ...
Authors:Shyng, S.L, Yoshioka, C, Martin, G.M, Sung, M.W.
Deposit date:2019-07-31
Release date:2019-08-14
Last modified:2020-10-07
Method:ELECTRON MICROSCOPY (3.74 Å)
Cite:Mechanism of pharmacochaperoning in a mammalian K ATP channel revealed by cryo-EM.
Elife, 8, 2019
6Q1E
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BU of 6q1e by Molmil
Inferred precursor (UCA) of the human antibody lineage 652
Descriptor: Fab heavy chain, Fab lambda chain
Authors:McCarthy, K.R, Harrison, S.C.
Deposit date:2019-08-03
Release date:2019-12-18
Last modified:2020-01-01
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Affinity maturation in a human humoral response to influenza hemagglutinin.
Proc.Natl.Acad.Sci.USA, 2019
6Q5N
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BU of 6q5n by Molmil
Crystal structure of a CC-Hex mutant that forms a parallel six-helix coiled coil CC-Hex*-L24Nle
Descriptor: 1,4-DIETHYLENE DIOXIDE, CC-Hex*-L24Nle, GLYCEROL
Authors:Wood, C.W, Beesley, J.L, Rhys, G.G, Brady, R.L, Woolfson, D.N.
Deposit date:2018-12-09
Release date:2019-05-22
Last modified:2019-06-19
Method:X-RAY DIFFRACTION (2 Å)
Cite:Navigating the Structural Landscape of De Novo alpha-Helical Bundles.
J.Am.Chem.Soc., 141, 2019
6PV3
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BU of 6pv3 by Molmil
Backbone-modified variant of zinc finger 2 from the transcription factor Sp1 DNA binding domain: altered helix, loop, turn, and sheet
Descriptor: Transcription factor Sp1, ZINC ION
Authors:Rao, S.R, Horne, W.S.
Deposit date:2019-07-19
Release date:2020-06-24
Last modified:2024-07-10
Method:SOLUTION NMR
Cite:Proteomimetic Zinc Finger Domains with Modified Metal-binding beta-Turns.
Pept Sci (Hoboken), 112, 2020
6G2T
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BU of 6g2t by Molmil
human cardiac myosin binding protein C C1 Ig-domain bound to native cardiac thin filament
Descriptor: Actin, cytoplasmic 2, Myosin-binding protein C, ...
Authors:Risi, C, Belknap, B, Forgacs, E, Harris, S.P, Schroder, G.F, White, H.D, Galkin, V.E.
Deposit date:2018-03-23
Release date:2018-10-17
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (9 Å)
Cite:N-Terminal Domains of Cardiac Myosin Binding Protein C Cooperatively Activate the Thin Filament.
Structure, 26, 2018
6Q0H
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BU of 6q0h by Molmil
Inferred intermediate I-7 (I-7-0) of the human antibody lineage 652 in complex with influenza hemagglutinin head domain of A/Beijing/262/95(H1N1)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab heavy chain, Fab lambda chain, ...
Authors:McCarthy, K.R, Harrison, S.C.
Deposit date:2019-08-01
Release date:2019-12-18
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Affinity maturation in a human humoral response to influenza hemagglutinin.
Proc.Natl.Acad.Sci.USA, 2019
6PX7
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BU of 6px7 by Molmil
Dg12a in Weaponisation 'on the fly': Convergent recruitment of knottin and defensin scaffolds as neurotoxins in the venom of assassin fly Dolopus genitalis (Diptera: Asilidae)
Descriptor: Venom polypeptide
Authors:Agwa, A.J, Schroeder, C.
Deposit date:2019-07-25
Release date:2020-01-22
Last modified:2020-02-05
Method:SOLUTION NMR
Cite:Weaponisation 'on the fly': Convergent recruitment of knottin and defensin peptide scaffolds into the venom of predatory assassin flies.
Insect Biochem.Mol.Biol., 118, 2019
6Q18
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BU of 6q18 by Molmil
Human antibody H1244 in complex with the influenza hemagglutinin head domain of A/Beijing/262/95(H1N1)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, H1244 Fab heavy chain, ...
Authors:McCarthy, K.R, Harrison, S.C.
Deposit date:2019-08-03
Release date:2019-12-18
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Affinity maturation in a human humoral response to influenza hemagglutinin.
Proc.Natl.Acad.Sci.USA, 2019
8PSV
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BU of 8psv by Molmil
2.7 A cryo-EM structure of in vitro assembled type 1 pilus rod
Descriptor: Type-1 fimbrial protein, A chain
Authors:Hospenthal, M, Zyla, D, Glockshuber, R, Waksman, G.
Deposit date:2023-07-13
Release date:2024-04-10
Last modified:2024-04-17
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:The assembly platform FimD is required to obtain the most stable quaternary structure of type 1 pili.
Nat Commun, 15, 2024
6QAN
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BU of 6qan by Molmil
Structure determination of N-terminal fragment of UL49.5 protein from bovine herpesvirus 1 by NMR spectroscopy and molecular dynamics
Descriptor: Envelope glycoprotein N
Authors:Karska, N, Rodziewicz-Motowidlo, S.
Deposit date:2018-12-19
Release date:2019-02-27
Last modified:2023-11-15
Method:SOLUTION NMR
Cite:Structure determination of UL49.5 transmembrane protein from bovine herpesvirus 1 by NMR spectroscopy and molecular dynamics.
Biochim Biophys Acta Biomembr, 1861, 2019
8PTU
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BU of 8ptu by Molmil
2.5 A cryo-EM structure of the in vitro FimD-catalyzed assembly of type 1 pilus rod
Descriptor: Type-1 fimbrial protein, A chain
Authors:Zyla, D, Hospenthal, M, Glockshuber, R, Waksman, G.
Deposit date:2023-07-14
Release date:2024-04-10
Last modified:2024-04-17
Method:ELECTRON MICROSCOPY (2.52 Å)
Cite:The assembly platform FimD is required to obtain the most stable quaternary structure of type 1 pili.
Nat Commun, 15, 2024
5YI5
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BU of 5yi5 by Molmil
human ferritin mutant - E-helix deletion
Descriptor: Ferritin heavy chain
Authors:Lee, S.G, Yoon, H.R, Ahn, B.J, Jeong, H, Hyun, J, Jung, Y, Kim, H.
Deposit date:2017-10-02
Release date:2018-02-21
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Four-fold Channel-Nicked Human Ferritin Nanocages for Active Drug Loading and pH-Responsive Drug Release
Angew. Chem. Int. Ed. Engl., 57, 2018
6PX8
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BU of 6px8 by Molmil
Dg3b in Weaponisation 'on the fly': Convergent recruitment of knottin and defensin scaffolds as neurotoxins in the venom of assassin fly Dolopus genitalis (Diptera: Asilidae)
Descriptor: Venom polypeptide
Authors:Agwa, A.J, Schroeder, C.
Deposit date:2019-07-25
Release date:2020-01-22
Last modified:2020-02-05
Method:SOLUTION NMR
Cite:Weaponisation 'on the fly': Convergent recruitment of knottin and defensin peptide scaffolds into the venom of predatory assassin flies.
Insect Biochem.Mol.Biol., 118, 2019
6Q19
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BU of 6q19 by Molmil
Inferred intermediate (I-6) of the human antibody lineage 652
Descriptor: Fab heavy chain, Fab lambda chain
Authors:McCarthy, K.R, Harrison, S.C.
Deposit date:2019-08-03
Release date:2019-12-18
Last modified:2020-01-01
Method:X-RAY DIFFRACTION (1.58 Å)
Cite:Affinity maturation in a human humoral response to influenza hemagglutinin.
Proc.Natl.Acad.Sci.USA, 2019
6Q1J
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BU of 6q1j by Molmil
Antibody H2227 from the human antibody lineage 652
Descriptor: Fab heavy chain, Fab lambda light chain
Authors:McCarthy, K.R, Harrison, S.C, Raymond, D.D.
Deposit date:2019-08-05
Release date:2019-12-18
Last modified:2020-01-01
Method:X-RAY DIFFRACTION (2.703 Å)
Cite:Affinity maturation in a human humoral response to influenza hemagglutinin.
Proc.Natl.Acad.Sci.USA, 2019
6Q31
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BU of 6q31 by Molmil
Dye type peroxidase Aa from Streptomyces lividans: 156.8 kGy structure
Descriptor: Deferrochelatase/peroxidase, PROTOPORPHYRIN IX CONTAINING FE
Authors:Ebrahim, A, Moreno-Chicano, T, Worrall, J.A.R, Strange, R.W, Axford, D, Sherrell, D.A, Appleby, M, Owen, R.L.
Deposit date:2018-12-03
Release date:2019-07-31
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Dose-resolved serial synchrotron and XFEL structures of radiation-sensitive metalloproteins.
Iucrj, 6, 2019
5YJ5
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BU of 5yj5 by Molmil
structure for wildtype Human prion protein (M129)
Descriptor: Major prion protein
Authors:Zheng, Z, Lin, D.
Deposit date:2017-10-08
Release date:2018-04-11
Last modified:2019-04-24
Method:SOLUTION NMR
Cite:Structural basis for the complete resistance of the human prion protein mutant G127V to prion disease.
Sci Rep, 8, 2018
5YKE
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BU of 5yke by Molmil
Structure of pancreatic ATP-sensitive potassium channel bound with glibenclamide and ATPgammaS (focused refinement on TM at 4.11A)
Descriptor: 5-chloro-N-(2-{4-[(cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-2-methoxybenzamide, ATP-binding cassette sub-family C member 8 isoform X2, ATP-sensitive inward rectifier potassium channel 11
Authors:Chen, L, Wu, J.X.
Deposit date:2017-10-14
Release date:2018-04-18
Last modified:2018-06-13
Method:ELECTRON MICROSCOPY (4.11 Å)
Cite:Ligand binding and conformational changes of SUR1 subunit in pancreatic ATP-sensitive potassium channels.
Protein Cell, 9, 2018
6Q5R
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BU of 6q5r by Molmil
Crystal structure of a CC-Hex mutant that forms an antiparallel four-helix coiled coil CC-Hex*-LL-KgEb
Descriptor: CC-Hex*-LL-KgEb, GLYCEROL
Authors:Beesley, J.L, Rhys, G.G, Wood, C.W, Brady, R.L, Woolfson, D.N.
Deposit date:2018-12-09
Release date:2019-05-22
Last modified:2019-06-19
Method:X-RAY DIFFRACTION (1.61 Å)
Cite:Navigating the Structural Landscape of De Novo alpha-Helical Bundles.
J.Am.Chem.Soc., 141, 2019
6Q34
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BU of 6q34 by Molmil
Dye type peroxidase Aa from Streptomyces lividans: 196 kGy structure
Descriptor: Deferrochelatase/peroxidase, PROTOPORPHYRIN IX CONTAINING FE
Authors:Ebrahim, A, Moreno-Chicano, T, Worrall, J.A.R, Strange, R.W, Axford, D, Sherrell, D.A, Appleby, M, Owen, R.L.
Deposit date:2018-12-03
Release date:2019-07-31
Last modified:2024-05-15
Method:X-RAY DIFFRACTION (1.82 Å)
Cite:Dose-resolved serial synchrotron and XFEL structures of radiation-sensitive metalloproteins.
Iucrj, 6, 2019
6Q5H
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BU of 6q5h by Molmil
Crystal structure of a CC-Hex mutant that forms an antiparallel four-helix coiled coil CC-Hex*-L24D
Descriptor: AMMONIUM ION, CC-Hex*-L24D, SULFATE ION
Authors:Wood, C.W, Beesley, J.L, Rhys, G.G, Brady, R.L, Woolfson, D.N.
Deposit date:2018-12-09
Release date:2019-05-22
Last modified:2019-06-19
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Navigating the Structural Landscape of De Novo alpha-Helical Bundles.
J.Am.Chem.Soc., 141, 2019
5YTD
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BU of 5ytd by Molmil
large fragment of DNA Polymerase I from Thermus aquaticus in a closed ternary complex with the natural base pair 5fC:dGTP
Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA (5'-D(*AP*AP*AP*(5FC)P*GP*GP*CP*GP*CP*CP*GP*TP*GP*GP*TP*C)-3'), DNA (5'-D(*GP*AP*CP*CP*AP*CP*GP*GP*CP*GP*CP*(DOC))-3'), ...
Authors:Zeng, H, Mondal, M, Song, R.Y, Zhang, J, Xia, B, Gao, Y.Q, Yi, C.Q.
Deposit date:2017-11-17
Release date:2018-11-21
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2 Å)
Cite:Unnatural Cytosine Bases Recognized as Thymines by DNA Polymerases by the Formation of the Watson-Crick Geometry.
Angew. Chem. Int. Ed. Engl., 58, 2019
6Q5K
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BU of 6q5k by Molmil
Crystal structure of a CC-Hex mutant that forms an antiparallel four-helix coiled coil CC-Hex*-L24K
Descriptor: AMMONIUM ION, CC-Hex*-L24K, GLYCEROL, ...
Authors:Wood, C.W, Beesley, J.L, Rhys, G.G, Brady, R.L, Woolfson, D.N.
Deposit date:2018-12-09
Release date:2019-05-22
Last modified:2019-06-19
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Navigating the Structural Landscape of De Novo alpha-Helical Bundles.
J.Am.Chem.Soc., 141, 2019
6Q5Q
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BU of 6q5q by Molmil
Crystal structure of a CC-Hex mutant that forms an antiparallel four-helix coiled coil CC-Hex-KgEb
Descriptor: CC-Hex-KgEb, L(+)-TARTARIC ACID
Authors:Zaccai, N.R, Rhys, G.G, Wood, C.W, Beesley, J.L, Brady, R.L, Woolfson, D.N.
Deposit date:2018-12-09
Release date:2019-05-22
Last modified:2019-06-19
Method:X-RAY DIFFRACTION (1.08 Å)
Cite:Navigating the Structural Landscape of De Novo alpha-Helical Bundles.
J.Am.Chem.Soc., 141, 2019
6PVR
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BU of 6pvr by Molmil
Influenza B M2 Proton Channel in the Closed State - SSNMR Structure at pH 7.5
Descriptor: BM2 protein
Authors:Mandala, V.S, Loftis, A.R, Shcherbakov, A.S, Pentelute, B.L, Hong, M.
Deposit date:2019-07-21
Release date:2020-02-05
Last modified:2024-05-01
Method:SOLID-STATE NMR
Cite:Atomic structures of closed and open influenza B M2 proton channel reveal the conduction mechanism.
Nat.Struct.Mol.Biol., 27, 2020

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數據於2024-09-11公開中

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