6KLD
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![BU of 6kld by Molmil](/molmil-images/mine/6kld) | Structure of apo Machupo virus polymerase | Descriptor: | MANGANESE (II) ION, RNA-directed RNA polymerase L, ZINC ION | Authors: | Peng, R, Xu, X, Jing, J, Peng, Q, Gao, G.F, Shi, Y. | Deposit date: | 2019-07-30 | Release date: | 2020-03-18 | Last modified: | 2021-12-08 | Method: | ELECTRON MICROSCOPY (3.58 Å) | Cite: | Structural insight into arenavirus replication machinery. Nature, 579, 2020
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7RDQ
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![BU of 7rdq by Molmil](/molmil-images/mine/7rdq) | |
7OM9
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![BU of 7om9 by Molmil](/molmil-images/mine/7om9) | |
5A2V
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![BU of 5a2v by Molmil](/molmil-images/mine/5a2v) | Crystal structure of mtPAP in Apo form | Descriptor: | CHLORIDE ION, MITOCHONDRIAL PROTEIN | Authors: | Lapkouski, M, Hallberg, B.M. | Deposit date: | 2015-05-26 | Release date: | 2015-09-09 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.82 Å) | Cite: | Structure of Mitochondrial Poly(A) RNA Polymerase Reveals the Structural Basis for Dimerization, ATP Selectivity and the Spax4 Disease Phenotype. Nucleic Acids Res., 43, 2015
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5A2Z
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![BU of 5a2z by Molmil](/molmil-images/mine/5a2z) | Crystal structure of mtPAP in complex with GTP | Descriptor: | GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, MITOCHONDRIAL PROTEIN | Authors: | Lapkouski, M, Hallberg, B.M. | Deposit date: | 2015-05-26 | Release date: | 2015-09-09 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Structure of Mitochondrial Poly(A) RNA Polymerase Reveals the Structural Basis for Dimerization, ATP Selectivity and the Spax4 Disease Phenotype. Nucleic Acids Res., 43, 2015
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5A2W
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![BU of 5a2w by Molmil](/molmil-images/mine/5a2w) | Crystal structure of mtPAP in complex with ATPgammaS | Descriptor: | DI(HYDROXYETHYL)ETHER, MAGNESIUM ION, MITOCHONDRIAL PROTEIN, ... | Authors: | Lapkouski, M, Hallberg, B.M. | Deposit date: | 2015-05-26 | Release date: | 2015-09-09 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structure of Mitochondrial Poly(A) RNA Polymerase Reveals the Structural Basis for Dimerization, ATP Selectivity and the Spax4 Disease Phenotype. Nucleic Acids Res., 43, 2015
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7VPD
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![BU of 7vpd by Molmil](/molmil-images/mine/7vpd) | |
5A2X
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![BU of 5a2x by Molmil](/molmil-images/mine/5a2x) | Crystal structure of mtPAP in complex with CTP | Descriptor: | CYTIDINE-5'-TRIPHOSPHATE, MAGNESIUM ION, MITOCHONDRIAL PROTEIN | Authors: | Lapkouski, M, Hallberg, B.M. | Deposit date: | 2015-05-26 | Release date: | 2015-09-09 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Structure of Mitochondrial Poly(A) RNA Polymerase Reveals the Structural Basis for Dimerization, ATP Selectivity and the Spax4 Disease Phenotype. Nucleic Acids Res., 43, 2015
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5A2Y
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![BU of 5a2y by Molmil](/molmil-images/mine/5a2y) | Crystal structure of mtPAP in complex with UTP | Descriptor: | MAGNESIUM ION, MITOCHONDRIAL PROTEIN, URIDINE 5'-TRIPHOSPHATE | Authors: | Lapkouski, M, Hallberg, B.M. | Deposit date: | 2015-05-26 | Release date: | 2015-09-09 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Structure of Mitochondrial Poly(A) RNA Polymerase Reveals the Structural Basis for Dimerization, ATP Selectivity and the Spax4 Disease Phenotype. Nucleic Acids Res., 43, 2015
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5A30
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![BU of 5a30 by Molmil](/molmil-images/mine/5a30) | Crystal structure of mtPAP N472D mutant in complex with ATPgammaS | Descriptor: | MAGNESIUM ION, MITOCHONDRIAL PROTEIN, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER | Authors: | Lapkouski, M, Hallberg, B.M. | Deposit date: | 2015-05-26 | Release date: | 2015-09-09 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Structure of Mitochondrial Poly(A) RNA Polymerase Reveals the Structural Basis for Dimerization, ATP Selectivity and the Spax4 Disease Phenotype. Nucleic Acids Res., 43, 2015
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7ORI
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![BU of 7ori by Molmil](/molmil-images/mine/7ori) | La Crosse virus polymerase at replication late-elongation stage | Descriptor: | La Crosse virus polymerase, MAGNESIUM ION, PYROPHOSPHATE 2-, ... | Authors: | Arragain, B, Durieux Trouilleton, Q, Baudin, F, Cusack, S, Schoehn, G, Malet, H. | Deposit date: | 2021-06-06 | Release date: | 2022-02-16 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Structural snapshots of La Crosse virus polymerase reveal the mechanisms underlying Peribunyaviridae replication and transcription. Nat Commun, 13, 2022
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6LBJ
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![BU of 6lbj by Molmil](/molmil-images/mine/6lbj) | |
6LBK
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![BU of 6lbk by Molmil](/molmil-images/mine/6lbk) | |
2GA9
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![BU of 2ga9 by Molmil](/molmil-images/mine/2ga9) | Crystal Structure of the Heterodimeric Vaccinia Virus Polyadenylate Polymerase with Bound ATP-gamma-S | Descriptor: | CALCIUM ION, Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... | Authors: | Moure, C.M, Bowman, B.R, Gershon, P.D, Quiocho, F.A. | Deposit date: | 2006-03-08 | Release date: | 2006-05-16 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal structures of the vaccinia virus polyadenylate polymerase heterodimer: insights into ATP selectivity and processivity. Mol.Cell, 22, 2006
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7EH0
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![BU of 7eh0 by Molmil](/molmil-images/mine/7eh0) | |
2GAF
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![BU of 2gaf by Molmil](/molmil-images/mine/2gaf) | Crystal Structure of the Vaccinia Polyadenylate Polymerase Heterodimer (apo form) | Descriptor: | Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase, Poly(A) polymerase catalytic subunit | Authors: | Moure, C.M, Bowman, B.R, Gershon, P.D, Quiocho, F.A. | Deposit date: | 2006-03-08 | Release date: | 2006-05-16 | Last modified: | 2021-10-20 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal structures of the vaccinia virus polyadenylate polymerase heterodimer: insights into ATP selectivity and processivity. Mol.Cell, 22, 2006
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7X76
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7X75
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![BU of 7x75 by Molmil](/molmil-images/mine/7x75) | |
7CKM
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![BU of 7ckm by Molmil](/molmil-images/mine/7ckm) | Structure of Machupo virus polymerase bound to Z matrix protein (monomeric complex) | Descriptor: | MANGANESE (II) ION, RING finger protein Z, RNA-directed RNA polymerase L, ... | Authors: | Xu, X, Peng, R, Peng, Q, Shi, Y. | Deposit date: | 2020-07-17 | Release date: | 2021-05-05 | Last modified: | 2021-11-17 | Method: | ELECTRON MICROSCOPY (3.37 Å) | Cite: | Cryo-EM structures of Lassa and Machupo virus polymerases complexed with cognate regulatory Z proteins identify targets for antivirals Nat Microbiol, 6, 2021
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7CKL
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![BU of 7ckl by Molmil](/molmil-images/mine/7ckl) | Structure of Lassa virus polymerase bound to Z matrix protein | Descriptor: | MANGANESE (II) ION, RING finger protein Z, RNA-directed RNA polymerase L, ... | Authors: | Xu, X, Peng, R, Peng, Q, Shi, Y. | Deposit date: | 2020-07-17 | Release date: | 2021-05-05 | Last modified: | 2021-11-17 | Method: | ELECTRON MICROSCOPY (3.88 Å) | Cite: | Cryo-EM structures of Lassa and Machupo virus polymerases complexed with cognate regulatory Z proteins identify targets for antivirals Nat Microbiol, 6, 2021
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7ORO
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![BU of 7oro by Molmil](/molmil-images/mine/7oro) | La Crosse virus polymerase at replication early-elongation stage | Descriptor: | La Crosse virus polymerase, MAGNESIUM ION, RNA (5'-R(P*AP*CP*GP*AP*GP*UP*GP*UP*CP*GP*UP*AP*CP*C)-3'), ... | Authors: | Arragain, B, Durieux Trouilleton, Q, Baudin, F, Cusack, S, Schoehn, G, Malet, H. | Deposit date: | 2021-06-06 | Release date: | 2022-02-16 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Structural snapshots of La Crosse virus polymerase reveal the mechanisms underlying Peribunyaviridae replication and transcription. Nat Commun, 13, 2022
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8P0G
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8P0B
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8P0U
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1FA0
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![BU of 1fa0 by Molmil](/molmil-images/mine/1fa0) | STRUCTURE OF YEAST POLY(A) POLYMERASE BOUND TO MANGANATE AND 3'-DATP | Descriptor: | 3'-DEOXYADENOSINE, 3'-DEOXYADENOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, ... | Authors: | Bard, J, Zhelkovsky, A.M, Helmling, S, Moore, C.L, Bohm, A. | Deposit date: | 2000-07-11 | Release date: | 2000-08-30 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structure of yeast poly(A) polymerase alone and in complex with 3'-dATP. Science, 289, 2000
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