8G3R
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![BU of 8g3r by Molmil](/molmil-images/mine/8g3r) | |
8G3M
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![BU of 8g3m by Molmil](/molmil-images/mine/8g3m) | |
8G3N
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![BU of 8g3n by Molmil](/molmil-images/mine/8g3n) | N2 neuraminidase of A/Tanzania/205/2010 H3N2 in complex with 4 FNI9 Fab molecules | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | Authors: | Dang, H, Snell, G. | Deposit date: | 2023-02-08 | Release date: | 2023-05-31 | Last modified: | 2023-06-28 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | A pan-influenza antibody inhibiting neuraminidase via receptor mimicry. Nature, 618, 2023
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8G3P
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![BU of 8g3p by Molmil](/molmil-images/mine/8g3p) | N2 neuraminidase of A/Hong_Kong/2671/2019 in complex with 4 FNI9 Fab molecules | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | Authors: | Dang, H.V, Snell, G. | Deposit date: | 2023-02-08 | Release date: | 2023-05-31 | Last modified: | 2023-06-28 | Method: | ELECTRON MICROSCOPY (2.5 Å) | Cite: | A pan-influenza antibody inhibiting neuraminidase via receptor mimicry. Nature, 618, 2023
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8G42
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![BU of 8g42 by Molmil](/molmil-images/mine/8g42) | KRAS G12C complex with GDP imaged on a cryo-EM imaging scaffold | Descriptor: | GTPase KRas, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Castells-Graells, R, Sawaya, M.R, Yeates, T.O. | Deposit date: | 2023-02-08 | Release date: | 2023-08-09 | Last modified: | 2023-09-27 | Method: | ELECTRON MICROSCOPY (3.02 Å) | Cite: | Cryo-EM structure determination of small therapeutic protein targets at 3 angstrom -resolution using a rigid imaging scaffold. Proc.Natl.Acad.Sci.USA, 120, 2023
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8IAH
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![BU of 8iah by Molmil](/molmil-images/mine/8iah) | Structure of mammalian spectrin-actin junctional complex of membrane skeleton, State I, Global map | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, cytoplasmic 1, ... | Authors: | Li, N, Chen, S, Gao, N. | Deposit date: | 2023-02-08 | Release date: | 2023-05-03 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Structural basis of membrane skeleton organization in red blood cells. Cell, 186, 2023
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8IAI
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![BU of 8iai by Molmil](/molmil-images/mine/8iai) | Structure of mammalian spectrin-actin junctional complex of membrane skeleton, State II, Global map | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, cytoplasmic 1, ... | Authors: | Li, N, Chen, S, Gao, N. | Deposit date: | 2023-02-08 | Release date: | 2023-05-03 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structural basis of membrane skeleton organization in red blood cells. Cell, 186, 2023
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8IA8
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![BU of 8ia8 by Molmil](/molmil-images/mine/8ia8) | Cryo-EM structure of C3aR-Gi-scFv16 bound with E7 peptide | Descriptor: | ALA-SER-LYS-LEU-GLY-LEU-ALA-ARG, C3a anaphylatoxin chemotactic receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | Authors: | Liao, Q, Chen, G, Du, Y, Ye, R.D. | Deposit date: | 2023-02-08 | Release date: | 2023-05-24 | Method: | ELECTRON MICROSCOPY (2.86 Å) | Cite: | Cryo-EM structure of C3aR-Gi-scFv16 bound with E7 peptide To Be Published
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8G3L
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![BU of 8g3l by Molmil](/molmil-images/mine/8g3l) | BceAB-S nucleotide free BceS state 2 | Descriptor: | Bacitracin export ATP-binding protein BceA, Bacitracin export permease protein BceB, OLEIC ACID, ... | Authors: | George, N.L, Orlando, B.J. | Deposit date: | 2023-02-08 | Release date: | 2023-06-21 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Architecture of a complete Bce-type antimicrobial peptide resistance module. Nat Commun, 14, 2023
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8IA7
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![BU of 8ia7 by Molmil](/molmil-images/mine/8ia7) | Structural insights into human brain gut peptide cholecystokinin receptors | Descriptor: | CCK-8, Gastrin/cholecystokinin type B receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | Authors: | Ding, Y, Zhang, H, Liao, Y, Chen, L, Ji, S. | Deposit date: | 2023-02-08 | Release date: | 2023-12-06 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Structural insights into human brain-gut peptide cholecystokinin receptors. Cell Discov, 8, 2022
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8G47
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![BU of 8g47 by Molmil](/molmil-images/mine/8g47) | KRAS G12C complex with GDP and AMG 510 imaged on a cryo-EM imaging scaffold | Descriptor: | AMG 510 (bound form), GTPase KRas, GUANOSINE-5'-DIPHOSPHATE, ... | Authors: | Castells-Graells, R, Sawaya, M.R, Yeates, T.O. | Deposit date: | 2023-02-08 | Release date: | 2023-08-09 | Last modified: | 2023-09-27 | Method: | ELECTRON MICROSCOPY (3.19 Å) | Cite: | Cryo-EM structure determination of small therapeutic protein targets at 3 angstrom -resolution using a rigid imaging scaffold. Proc.Natl.Acad.Sci.USA, 120, 2023
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8CI3
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![BU of 8ci3 by Molmil](/molmil-images/mine/8ci3) | Structure of bovine CD46 ectodomain (SCR 1-2) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ... | Authors: | Aitkenhead, H, David I Stuart, D.I, El Omari, K. | Deposit date: | 2023-02-08 | Release date: | 2023-07-12 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.33 Å) | Cite: | Structure of Bovine CD46 Ectodomain. Viruses, 15, 2023
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8CHF
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![BU of 8chf by Molmil](/molmil-images/mine/8chf) | cryo-EM Structure of Craf:14-3-3:Mek1 | Descriptor: | 14-3-3 protein zeta isoform X1, 2-{4-[(1E)-1-(hydroxyimino)-2,3-dihydro-1H-inden-5-yl]-3-(pyridin-4-yl)-1H-pyrazol-1-yl}ethanol, Dual specificity mitogen-activated protein kinase kinase 1, ... | Authors: | Dedden, D, Ulrich, G. | Deposit date: | 2023-02-07 | Release date: | 2024-02-21 | Last modified: | 2024-02-28 | Method: | ELECTRON MICROSCOPY (4.25 Å) | Cite: | Cryo-EM Structures of CRAF 2 /14-3-3 2 and CRAF 2 /14-3-3 2 /MEK1 2 Complexes. J.Mol.Biol., 436, 2024
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8CH6
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![BU of 8ch6 by Molmil](/molmil-images/mine/8ch6) | Structure of a late-stage activated spliceosome (BAqr) arrested with a dominant-negative Aquarius mutant (state B complex). | Descriptor: | 116 kDa U5 small nuclear ribonucleoprotein component, BUD13 homolog, Cell division cycle 5-like protein, ... | Authors: | Cretu, C, Schmitzova, J, Pena, V. | Deposit date: | 2023-02-07 | Release date: | 2023-05-10 | Last modified: | 2023-06-14 | Method: | ELECTRON MICROSCOPY (5.9 Å) | Cite: | Structural basis of catalytic activation in human splicing. Nature, 617, 2023
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8CHB
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![BU of 8chb by Molmil](/molmil-images/mine/8chb) | Inward-facing conformation of the ABC transporter BmrA C436S/A582C cross-linked mutant | Descriptor: | Multidrug resistance ABC transporter ATP-binding/permease protein BmrA | Authors: | Di Cesare, M, Kaplan, E, Hanssen, E, Valimehr, S, Orelle, C, Jault, J.M. | Deposit date: | 2023-02-07 | Release date: | 2023-12-20 | Last modified: | 2024-01-24 | Method: | ELECTRON MICROSCOPY (3.14 Å) | Cite: | The transport activity of the multidrug ABC transporter BmrA does not require a wide separation of the nucleotide-binding domains. J.Biol.Chem., 300, 2023
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8G3D
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![BU of 8g3d by Molmil](/molmil-images/mine/8g3d) | 48-nm doublet microtubule from Tetrahymena thermophila strain K40R | Descriptor: | B2B3_fMIP, B5B6_fMIP, CFAM166A, ... | Authors: | Black, C.S, Kubo, S, Yang, S.K, Bui, K.H. | Deposit date: | 2023-02-07 | Release date: | 2023-06-14 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Native doublet microtubules from Tetrahymena thermophila reveal the importance of outer junction proteins. Nat Commun, 14, 2023
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8G3F
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![BU of 8g3f by Molmil](/molmil-images/mine/8g3f) | BceAB-S nucleotide free BceS state 1 | Descriptor: | Bacitracin export ATP-binding protein BceA, Bacitracin export permease protein BceB, OLEIC ACID, ... | Authors: | George, N.L, Orlando, B.J. | Deposit date: | 2023-02-07 | Release date: | 2023-06-21 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Architecture of a complete Bce-type antimicrobial peptide resistance module. Nat Commun, 14, 2023
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8G3B
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![BU of 8g3b by Molmil](/molmil-images/mine/8g3b) | BceAB-S nucleotide free TM state 2 | Descriptor: | Bacitracin export ATP-binding protein BceA, Bacitracin export permease protein BceB, OLEIC ACID, ... | Authors: | George, N.L, Orlando, B.J. | Deposit date: | 2023-02-07 | Release date: | 2023-06-21 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Architecture of a complete Bce-type antimicrobial peptide resistance module. Nat Commun, 14, 2023
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8I9J
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![BU of 8i9j by Molmil](/molmil-images/mine/8i9j) | The PKR and E3L complex | Descriptor: | Interferon-induced, double-stranded RNA-activated protein kinase, RNA-binding protein E3 | Authors: | Han, C.W, Kim, H.J. | Deposit date: | 2023-02-07 | Release date: | 2023-06-28 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (6.39 Å) | Cite: | Structural study of novel vaccinia virus E3L and dsRNA-dependent protein kinase complex. Biochem.Biophys.Res.Commun., 665, 2023
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8I9T
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![BU of 8i9t by Molmil](/molmil-images/mine/8i9t) | Cryo-EM structure of a Chaetomium thermophilum pre-60S ribosomal subunit - State Dbp10-1 | Descriptor: | 60S ribosomal protein L12-like protein, 60S ribosomal protein L13, 60S ribosomal protein L14-like protein, ... | Authors: | Lau, B, Huang, Z, Beckmann, R, Hurt, E, Cheng, J. | Deposit date: | 2023-02-07 | Release date: | 2023-05-17 | Last modified: | 2023-07-19 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Mechanism of 5S RNP recruitment and helicase-surveilled rRNA maturation during pre-60S biogenesis. Embo Rep., 24, 2023
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8I9P
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![BU of 8i9p by Molmil](/molmil-images/mine/8i9p) | Cryo-EM structure of a Chaetomium thermophilum pre-60S ribosomal subunit - State Mak16 | Descriptor: | 60S ribosomal protein L13, 60S ribosomal protein L14-like protein, 60S ribosomal protein L16-like protein, ... | Authors: | Lau, B, Huang, Z, Beckmann, R, Hurt, E, Cheng, J. | Deposit date: | 2023-02-07 | Release date: | 2023-05-17 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Mechanism of 5S RNP recruitment and helicase-surveilled rRNA maturation during pre-60S biogenesis. Embo Rep., 24, 2023
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8I9Z
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![BU of 8i9z by Molmil](/molmil-images/mine/8i9z) | Cryo-EM structure of a Chaetomium thermophilum pre-60S ribosomal subunit - State Spb4 | Descriptor: | 60S ribosomal protein L12-like protein, 60S ribosomal protein L13, 60S ribosomal protein L14-like protein, ... | Authors: | Lau, B, Huang, Z, Beckmann, R, Hurt, E, Cheng, J. | Deposit date: | 2023-02-07 | Release date: | 2023-05-17 | Last modified: | 2023-07-19 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | Mechanism of 5S RNP recruitment and helicase-surveilled rRNA maturation during pre-60S biogenesis. Embo Rep., 24, 2023
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8I9X
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![BU of 8i9x by Molmil](/molmil-images/mine/8i9x) | Cryo-EM structure of a Chaetomium thermophilum pre-60S ribosomal subunit - Ytm1-1 | Descriptor: | 60S ribosomal protein L12-like protein, 60S ribosomal protein L13, 60S ribosomal protein L14-like protein, ... | Authors: | Lau, B, Huang, Z, Beckmann, R, Hurt, E, Cheng, J. | Deposit date: | 2023-02-07 | Release date: | 2023-05-17 | Last modified: | 2023-07-19 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Mechanism of 5S RNP recruitment and helicase-surveilled rRNA maturation during pre-60S biogenesis. Embo Rep., 24, 2023
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8IA0
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![BU of 8ia0 by Molmil](/molmil-images/mine/8ia0) | Cryo-EM structure of a Chaetomium thermophilum pre-60S ribosomal subunit - State Puf6 | Descriptor: | 60S ribosomal protein L12-like protein, 60S ribosomal protein L13, 60S ribosomal protein L14-like protein, ... | Authors: | Lau, B, Huang, Z, Beckmann, R, Hurt, E, Cheng, J. | Deposit date: | 2023-02-07 | Release date: | 2023-05-17 | Last modified: | 2023-07-19 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | Mechanism of 5S RNP recruitment and helicase-surveilled rRNA maturation during pre-60S biogenesis. Embo Rep., 24, 2023
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8I9R
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![BU of 8i9r by Molmil](/molmil-images/mine/8i9r) | Cryo-EM structure of a Chaetomium thermophilum pre-60S ribosomal subunit - State 5S RNP | Descriptor: | 60S ribosomal protein L13, 60S ribosomal protein L14-like protein, 60S ribosomal protein L16-like protein, ... | Authors: | Lau, B, Huang, Z, Beckmann, R, Hurt, E, Cheng, J. | Deposit date: | 2023-02-07 | Release date: | 2023-05-17 | Last modified: | 2023-07-19 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Mechanism of 5S RNP recruitment and helicase-surveilled rRNA maturation during pre-60S biogenesis. Embo Rep., 24, 2023
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