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8R1F	Monomeric E6AP-E6-p53 ternary complex Descriptor: Cellular tumor antigen p53, Ubiquitin-like protein SMT3,Protein E6, Ubiquitin-protein ligase E3A, ... Authors: Sandate, C.R, Chakraborty, D, Kater, L, Kempf, G, Thoma, N.H. Deposit date: 2023-11-01 Release date: 2023-12-06 Last modified: 2024-06-19 Method: ELECTRON MICROSCOPY (3.67 Å) Cite: Structural insights into viral hijacking of p53 by E6 and E6AP Biorxiv, 2023
3IGL	Diversity in DNA recognition by p53 revealed by crystal structures with Hoogsteen base pairs (p53-DNA complex 1) Descriptor: 1,2-ETHANEDIOL, Cellular tumor antigen p53, DNA (5'-D(*CP*GP*GP*GP*CP*AP*TP*GP*CP*CP*CP*G)-3'), ... Authors: Kitayner, M, Suad, O, Rozenberg, H, Shakked, Z. Deposit date: 2009-07-28 Release date: 2010-03-31 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Diversity in DNA recognition by p53 revealed by crystal structures with Hoogsteen base pairs Nat.Struct.Mol.Biol., 17, 2010
3EXJ	Crystal Structure of a p53 Core Tetramer Bound to DNA Descriptor: 5'-D(*DTP*DTP*DGP*DAP*DGP*DCP*DAP*DTP*DGP*DCP*DTP*DC)-3', 5'-D(P*DGP*DAP*DGP*DCP*DAP*DTP*DGP*DCP*DTP*DCP*DA)-3', CITRATE ANION, ... Authors: Malecka, K.A. Deposit date: 2008-10-16 Release date: 2008-12-16 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (2 Å) Cite: Crystal structure of a p53 core tetramer bound to DNA. Oncogene, 28, 2009
3KMD	Crystal structure of the p53 core domain bound to a full consensus site as a self-assembled tetramer Descriptor: 5'-D(*GP*GP*GP*CP*AP*TP*GP*CP*CP*TP*AP*GP*GP*CP*AP*TP*GP*CP*C)-3', Cellular tumor antigen p53, ZINC ION Authors: Chen, Y, Dey, R, Chen, L. Deposit date: 2009-11-10 Release date: 2010-02-23 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.15 Å) Cite: Crystal structure of the p53 core domain bound to a full consensus site as a self-assembled tetramer. Structure, 18, 2010
3GCT	STRUCTURE OF GAMMA-*CHYMOTRYPSIN IN THE RANGE $P*H 2.0 TO $P*H 10.5 SUGGESTS THAT GAMMA-CHYMOTRYPSIN IS A COVALENT ACYL-ENZYME ADDUCT AT LOW $P*H Descriptor: GAMMA-CHYMOTRYPSIN A, SULFATE ION, UNK PRO GLY ALA TYR PEPTIDE Authors: Dixon, M.M, Matthews, B.W. Deposit date: 1990-09-04 Release date: 1991-10-15 Last modified: 2024-06-05 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Structure of gamma-chymotrypsin in the range pH 2.0 to pH 10.5 suggests that gamma-chymotrypsin is a covalent acyl-enzyme adduct at low pH. Int.J.Biol.Macromol., 13, 1991
3GCH	CHEMISTRY OF CAGED ENZYMES. BINDING OF PHOTOREVERSIBLE CINNAMATES TO CHYMOTRYPSIN Descriptor: GAMMA-CHYMOTRYPSIN, TRANS-O-HYDROXY-ALPHA-METHYL CINNAMATE Authors: Stoddard, B.L, Ringe, D, Petsko, G.A. Deposit date: 1989-09-25 Release date: 1990-10-15 Last modified: 2024-06-05 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Structure and activity of two photoreversible cinnamates bound to chymotrypsin. Biochemistry, 29, 1990
6NMI	Cryo-EM structure of the human TFIIH core complex Descriptor: CDK-activating kinase assembly factor MAT1, General transcription and DNA repair factor IIH helicase subunit XPB, General transcription and DNA repair factor IIH helicase subunit XPD, ... Authors: Greber, B.J, Toso, D, Fang, J, Nogales, E. Deposit date: 2019-01-10 Release date: 2019-03-13 Last modified: 2019-12-18 Method: ELECTRON MICROSCOPY (3.7 Å) Cite: The complete structure of the human TFIIH core complex. Elife, 8, 2019
5HJ0	Crystal Structure of Mis18 'Yippee-like' Domain Descriptor: Kinetochore protein mis18, ZINC ION Authors: Medina-Pritchard, B, Subramanian, L, Allshire, R, Arockia Jeyaprakash, A. Deposit date: 2016-01-12 Release date: 2016-03-09 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (2.64 Å) Cite: Centromere localization and function of Mis18 requires Yippee-like domain-mediated oligomerization. Embo Rep., 17, 2016
3KZ8	Diversity in DNA recognition by p53 revealed by crystal structures with Hoogsteen base pairs (p53-DNA complex 3) Descriptor: Cellular tumor antigen p53, DNA (5'-D(*TP*GP*GP*GP*CP*AP*TP*GP*CP*CP*CP*GP*GP*GP*CP*AP*TP*GP*CP*CP*C)-3'), IODIDE ION, ... Authors: Rozenberg, H, Suad, O, Shakked, Z. Deposit date: 2009-12-08 Release date: 2010-03-31 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (1.91 Å) Cite: Diversity in DNA recognition by p53 revealed by crystal structures with Hoogsteen base pairs Nat.Struct.Mol.Biol., 17, 2010
4KVP	Human p53 Core Domain Mutant V157F Descriptor: Cellular tumor antigen p53, ZINC ION Authors: Wallentine, B.D, Wang, Y, Luecke, H. Deposit date: 2013-05-22 Release date: 2013-07-31 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Structures of oncogenic, suppressor and rescued p53 core-domain variants: mechanisms of mutant p53 rescue. Acta Crystallogr.,Sect.D, 69, 2013
5MCU	New Insights into the Role of DNA Shape on Its Recognition by p53 Proteins (complex p53DBD-LHG2) Descriptor: 1,2-ETHANEDIOL, Cellular tumor antigen p53, DNA, ... Authors: Golovenko, D, Rozenberg, H, Shakked, Z. Deposit date: 2016-11-10 Release date: 2018-06-13 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.7 Å) Cite: New Insights into the Role of DNA Shape on Its Recognition by p53 Proteins. Structure, 26, 2018
5MCW	New Insights into the Role of DNA Shape on Its Recognition by p53 Proteins (complex p53DBD-LWC2) Descriptor: Cellular tumor antigen p53, DNA, FORMYL GROUP, ... Authors: Golovenko, D, Rozenberg, H, Shakked, Z. Deposit date: 2016-11-10 Release date: 2018-06-13 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.897 Å) Cite: New Insights into the Role of DNA Shape on Its Recognition by p53 Proteins. Structure, 26, 2018
5MF7	New Insights into the Role of DNA Shape on Its Recognition by p53 Proteins (complex p53DBD-GADD45) Descriptor: Cellular tumor antigen p53, DI(HYDROXYETHYL)ETHER, DNA, ... Authors: Rozenberg, H, Diskin-Posner, Y, Golovenko, D, Shakked, Z. Deposit date: 2016-11-17 Release date: 2018-05-30 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.59 Å) Cite: New Insights into the Role of DNA Shape on Its Recognition by p53 Proteins. Structure, 26, 2018
5MCT	New Insights into the Role of DNA Shape on Its Recognition by p53 Proteins (complex p53DBD-LHG1) Descriptor: 1,2-ETHANEDIOL, Cellular tumor antigen p53, DNA, ... Authors: Golovenko, D, Rozenberg, H, Shakked, Z. Deposit date: 2016-11-10 Release date: 2018-06-13 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.446 Å) Cite: New Insights into the Role of DNA Shape on Its Recognition by p53 Proteins. Structure, 26, 2018
1IGA	MODEL OF HUMAN IGA1 DETERMINED BY SOLUTION SCATTERING CURVE-FITTING AND HOMOLOGY MODELLING Descriptor: IGA1 Authors: Boehm, M.K, Woof, J.M, Kerr, M.A, Perkins, S.J. Deposit date: 1998-12-23 Release date: 1999-06-15 Last modified: 2024-02-07 Method: SOLUTION SCATTERING Cite: The Fab and Fc fragments of IgA1 exhibit a different arrangement from that in IgG: a study by X-ray and neutron solution scattering and homology modelling. J.Mol.Biol., 286, 1999
7DVD	The crystal structure of p53 DNA binding domain and PUMA complex Descriptor: Bcl-2-binding component 3, isoforms 1/2, Cellular tumor antigen p53, ... Authors: Han, C.W, Lee, H.N, Jeong, M.S, Jang, S.B. Deposit date: 2021-01-13 Release date: 2021-08-04 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.59 Å) Cite: Structural basis of the p53 DNA binding domain and PUMA complex. Biochem.Biophys.Res.Commun., 548, 2021
4MZR	Crystal structure of a polypeptide p53 mutant bound to DNA Descriptor: Cellular tumor antigen p53, ZINC ION, consensus DNA anti-sense strand, ... Authors: Emamzadah, S.T, Tropia, L, Vincenti, I, Falquet, B, Halazonetis, T.D. Deposit date: 2013-09-30 Release date: 2014-01-15 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Reversal of the DNA-Binding-Induced Loop L1 Conformational Switch in an Engineered Human p53 Protein. J.Mol.Biol., 426, 2014
4MZI	Crystal structure of a human mutant p53 Descriptor: Cellular tumor antigen p53, ZINC ION Authors: Emamzadah, S, Tropia, L, Vincenti, I, Falquet, B, Halazonetis, T.D. Deposit date: 2013-09-30 Release date: 2014-01-15 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (1.25 Å) Cite: Reversal of the DNA-Binding-Induced Loop L1 Conformational Switch in an Engineered Human p53 Protein. J.Mol.Biol., 426, 2014
5CHA	THE REFINEMENT AND THE STRUCTURE OF THE DIMER OF ALPHA-*CHYMOTRYPSIN AT 1.67-*ANGSTROMS RESOLUTION Descriptor: ALPHA-CHYMOTRYPSIN A Authors: Blevins, R.A, Tulinsky, A. Deposit date: 1985-01-22 Release date: 1985-04-01 Last modified: 2024-06-05 Method: X-RAY DIFFRACTION (1.67 Å) Cite: The refinement and the structure of the dimer of alpha-chymotrypsin at 1.67-A resolution. J.Biol.Chem., 260, 1985
7EDS	Human p53 core domain with germline hot spot mutation M133T in complex with the natural PIG3 p53-response element and Arsenic Descriptor: ARSENIC, Cellular tumor antigen p53, PIG3 anti-sense strand, ... Authors: Xing, Y.F, Lu, M. Deposit date: 2021-03-17 Release date: 2022-06-22 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (1.77 Å) Cite: Arsenic-bound p53 Hotspot mutant M133T in complex with the natural PIG3 p53-response element To Be Published
7EEU	Human p53 core domain with hot spot mutation R282W in complex with the natural CDKN1A(p21) p53-response element and Arsenic Descriptor: ARSENIC, CDKN1A(p21) anti-sense strand, CDKN1A(p21) sense strand, ... Authors: Xing, Y.F, Lu, M. Deposit date: 2021-03-19 Release date: 2022-06-22 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Human p53 core domain with hot spot mutation R282W in complex with the natural CDKN1A(p21) p53-response element and Arsenic To Be Published
1KDQ	Crystal Structure Analysis of the Mutant S189D Rat Chymotrypsin Descriptor: CALCIUM ION, CHYMOTRYPSIN B, B CHAIN, ... Authors: Szabo, E, Bocskei, Z, Naray-Szabo, G, Graf, L, Venekei, I. Deposit date: 2001-11-13 Release date: 2003-06-10 Last modified: 2021-10-27 Method: X-RAY DIFFRACTION (2.55 Å) Cite: Three Dimensional Structures of S189D Chymotrypsin and D189S Trypsin Mutants: The Effect of Polarity at Site 189 on a Protease-specific Stabilization of the Substrate-binding Site J.Mol.Biol., 331, 2003
5MCV	New Insights into the Role of DNA Shape on Its Recognition by p53 Proteins (complex p53DBD-LWC1) Descriptor: 1,2-ETHANEDIOL, ACETATE ION, Cellular tumor antigen p53, ... Authors: Golovenko, D, Rozenberg, H, Shakked, Z. Deposit date: 2016-11-10 Release date: 2018-06-13 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.6 Å) Cite: New Insights into the Role of DNA Shape on Its Recognition by p53 Proteins. Structure, 26, 2018
1YCS	P53-53BP2 COMPLEX Descriptor: 53BP2, P53, ZINC ION Authors: Gorina, S, Pavletich, N.P. Deposit date: 1996-09-30 Release date: 1997-11-19 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Structure of the p53 tumor suppressor bound to the ankyrin and SH3 domains of 53BP2. Science, 274, 1996
1YPH	High resolution structure of bovine alpha-chymotrypsin Descriptor: CHYMOTRYPSIN A, chain A, chain B, ... Authors: Razeto, A, Galunsky, B, Kasche, V, Wilson, K.S, Lamzin, V.S. Deposit date: 2005-01-31 Release date: 2006-02-14 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (1.34 Å) Cite: High resolution structure of native bovine alpha-chymotrypsin To be Published

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