8R1F
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![BU of 8r1f by Molmil](/molmil-images/mine/8r1f) | Monomeric E6AP-E6-p53 ternary complex | Descriptor: | Cellular tumor antigen p53, Ubiquitin-like protein SMT3,Protein E6, Ubiquitin-protein ligase E3A, ... | Authors: | Sandate, C.R, Chakraborty, D, Kater, L, Kempf, G, Thoma, N.H. | Deposit date: | 2023-11-01 | Release date: | 2023-12-06 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (3.67 Å) | Cite: | Structural insights into viral hijacking of p53 by E6 and E6AP Biorxiv, 2023
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3IGL
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![BU of 3igl by Molmil](/molmil-images/mine/3igl) | Diversity in DNA recognition by p53 revealed by crystal structures with Hoogsteen base pairs (p53-DNA complex 1) | Descriptor: | 1,2-ETHANEDIOL, Cellular tumor antigen p53, DNA (5'-D(*CP*GP*GP*GP*CP*AP*TP*GP*CP*CP*CP*G)-3'), ... | Authors: | Kitayner, M, Suad, O, Rozenberg, H, Shakked, Z. | Deposit date: | 2009-07-28 | Release date: | 2010-03-31 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Diversity in DNA recognition by p53 revealed by crystal structures with Hoogsteen base pairs Nat.Struct.Mol.Biol., 17, 2010
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3EXJ
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![BU of 3exj by Molmil](/molmil-images/mine/3exj) | Crystal Structure of a p53 Core Tetramer Bound to DNA | Descriptor: | 5'-D(*DTP*DTP*DGP*DAP*DGP*DCP*DAP*DTP*DGP*DCP*DTP*DC)-3', 5'-D(P*DGP*DAP*DGP*DCP*DAP*DTP*DGP*DCP*DTP*DCP*DA)-3', CITRATE ANION, ... | Authors: | Malecka, K.A. | Deposit date: | 2008-10-16 | Release date: | 2008-12-16 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structure of a p53 core tetramer bound to DNA. Oncogene, 28, 2009
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3KMD
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![BU of 3kmd by Molmil](/molmil-images/mine/3kmd) | |
3GCT
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![BU of 3gct by Molmil](/molmil-images/mine/3gct) | |
3GCH
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![BU of 3gch by Molmil](/molmil-images/mine/3gch) | |
6NMI
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![BU of 6nmi by Molmil](/molmil-images/mine/6nmi) | Cryo-EM structure of the human TFIIH core complex | Descriptor: | CDK-activating kinase assembly factor MAT1, General transcription and DNA repair factor IIH helicase subunit XPB, General transcription and DNA repair factor IIH helicase subunit XPD, ... | Authors: | Greber, B.J, Toso, D, Fang, J, Nogales, E. | Deposit date: | 2019-01-10 | Release date: | 2019-03-13 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | The complete structure of the human TFIIH core complex. Elife, 8, 2019
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5HJ0
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![BU of 5hj0 by Molmil](/molmil-images/mine/5hj0) | Crystal Structure of Mis18 'Yippee-like' Domain | Descriptor: | Kinetochore protein mis18, ZINC ION | Authors: | Medina-Pritchard, B, Subramanian, L, Allshire, R, Arockia Jeyaprakash, A. | Deposit date: | 2016-01-12 | Release date: | 2016-03-09 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.64 Å) | Cite: | Centromere localization and function of Mis18 requires Yippee-like domain-mediated oligomerization. Embo Rep., 17, 2016
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3KZ8
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![BU of 3kz8 by Molmil](/molmil-images/mine/3kz8) | Diversity in DNA recognition by p53 revealed by crystal structures with Hoogsteen base pairs (p53-DNA complex 3) | Descriptor: | Cellular tumor antigen p53, DNA (5'-D(*TP*GP*GP*GP*CP*AP*TP*GP*CP*CP*CP*GP*GP*GP*CP*AP*TP*GP*CP*CP*C)-3'), IODIDE ION, ... | Authors: | Rozenberg, H, Suad, O, Shakked, Z. | Deposit date: | 2009-12-08 | Release date: | 2010-03-31 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.91 Å) | Cite: | Diversity in DNA recognition by p53 revealed by crystal structures with Hoogsteen base pairs Nat.Struct.Mol.Biol., 17, 2010
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4KVP
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![BU of 4kvp by Molmil](/molmil-images/mine/4kvp) | Human p53 Core Domain Mutant V157F | Descriptor: | Cellular tumor antigen p53, ZINC ION | Authors: | Wallentine, B.D, Wang, Y, Luecke, H. | Deposit date: | 2013-05-22 | Release date: | 2013-07-31 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Structures of oncogenic, suppressor and rescued p53 core-domain variants: mechanisms of mutant p53 rescue. Acta Crystallogr.,Sect.D, 69, 2013
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5MCU
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![BU of 5mcu by Molmil](/molmil-images/mine/5mcu) | New Insights into the Role of DNA Shape on Its Recognition by p53 Proteins (complex p53DBD-LHG2) | Descriptor: | 1,2-ETHANEDIOL, Cellular tumor antigen p53, DNA, ... | Authors: | Golovenko, D, Rozenberg, H, Shakked, Z. | Deposit date: | 2016-11-10 | Release date: | 2018-06-13 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | New Insights into the Role of DNA Shape on Its Recognition by p53 Proteins. Structure, 26, 2018
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5MCW
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![BU of 5mcw by Molmil](/molmil-images/mine/5mcw) | New Insights into the Role of DNA Shape on Its Recognition by p53 Proteins (complex p53DBD-LWC2) | Descriptor: | Cellular tumor antigen p53, DNA, FORMYL GROUP, ... | Authors: | Golovenko, D, Rozenberg, H, Shakked, Z. | Deposit date: | 2016-11-10 | Release date: | 2018-06-13 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.897 Å) | Cite: | New Insights into the Role of DNA Shape on Its Recognition by p53 Proteins. Structure, 26, 2018
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5MF7
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![BU of 5mf7 by Molmil](/molmil-images/mine/5mf7) | New Insights into the Role of DNA Shape on Its Recognition by p53 Proteins (complex p53DBD-GADD45) | Descriptor: | Cellular tumor antigen p53, DI(HYDROXYETHYL)ETHER, DNA, ... | Authors: | Rozenberg, H, Diskin-Posner, Y, Golovenko, D, Shakked, Z. | Deposit date: | 2016-11-17 | Release date: | 2018-05-30 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.59 Å) | Cite: | New Insights into the Role of DNA Shape on Its Recognition by p53 Proteins. Structure, 26, 2018
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5MCT
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![BU of 5mct by Molmil](/molmil-images/mine/5mct) | New Insights into the Role of DNA Shape on Its Recognition by p53 Proteins (complex p53DBD-LHG1) | Descriptor: | 1,2-ETHANEDIOL, Cellular tumor antigen p53, DNA, ... | Authors: | Golovenko, D, Rozenberg, H, Shakked, Z. | Deposit date: | 2016-11-10 | Release date: | 2018-06-13 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.446 Å) | Cite: | New Insights into the Role of DNA Shape on Its Recognition by p53 Proteins. Structure, 26, 2018
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1IGA
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![BU of 1iga by Molmil](/molmil-images/mine/1iga) | |
7DVD
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![BU of 7dvd by Molmil](/molmil-images/mine/7dvd) | The crystal structure of p53 DNA binding domain and PUMA complex | Descriptor: | Bcl-2-binding component 3, isoforms 1/2, Cellular tumor antigen p53, ... | Authors: | Han, C.W, Lee, H.N, Jeong, M.S, Jang, S.B. | Deposit date: | 2021-01-13 | Release date: | 2021-08-04 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.59 Å) | Cite: | Structural basis of the p53 DNA binding domain and PUMA complex. Biochem.Biophys.Res.Commun., 548, 2021
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4MZR
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![BU of 4mzr by Molmil](/molmil-images/mine/4mzr) | Crystal structure of a polypeptide p53 mutant bound to DNA | Descriptor: | Cellular tumor antigen p53, ZINC ION, consensus DNA anti-sense strand, ... | Authors: | Emamzadah, S.T, Tropia, L, Vincenti, I, Falquet, B, Halazonetis, T.D. | Deposit date: | 2013-09-30 | Release date: | 2014-01-15 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Reversal of the DNA-Binding-Induced Loop L1 Conformational Switch in an Engineered Human p53 Protein. J.Mol.Biol., 426, 2014
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4MZI
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![BU of 4mzi by Molmil](/molmil-images/mine/4mzi) | Crystal structure of a human mutant p53 | Descriptor: | Cellular tumor antigen p53, ZINC ION | Authors: | Emamzadah, S, Tropia, L, Vincenti, I, Falquet, B, Halazonetis, T.D. | Deposit date: | 2013-09-30 | Release date: | 2014-01-15 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (1.25 Å) | Cite: | Reversal of the DNA-Binding-Induced Loop L1 Conformational Switch in an Engineered Human p53 Protein. J.Mol.Biol., 426, 2014
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5CHA
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![BU of 5cha by Molmil](/molmil-images/mine/5cha) | |
7EDS
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![BU of 7eds by Molmil](/molmil-images/mine/7eds) | |
7EEU
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![BU of 7eeu by Molmil](/molmil-images/mine/7eeu) | |
1KDQ
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![BU of 1kdq by Molmil](/molmil-images/mine/1kdq) | Crystal Structure Analysis of the Mutant S189D Rat Chymotrypsin | Descriptor: | CALCIUM ION, CHYMOTRYPSIN B, B CHAIN, ... | Authors: | Szabo, E, Bocskei, Z, Naray-Szabo, G, Graf, L, Venekei, I. | Deposit date: | 2001-11-13 | Release date: | 2003-06-10 | Last modified: | 2021-10-27 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | Three Dimensional Structures of S189D Chymotrypsin and D189S Trypsin Mutants: The Effect of Polarity at Site 189 on a Protease-specific Stabilization of
the Substrate-binding Site J.Mol.Biol., 331, 2003
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5MCV
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![BU of 5mcv by Molmil](/molmil-images/mine/5mcv) | New Insights into the Role of DNA Shape on Its Recognition by p53 Proteins (complex p53DBD-LWC1) | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, Cellular tumor antigen p53, ... | Authors: | Golovenko, D, Rozenberg, H, Shakked, Z. | Deposit date: | 2016-11-10 | Release date: | 2018-06-13 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | New Insights into the Role of DNA Shape on Its Recognition by p53 Proteins. Structure, 26, 2018
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1YCS
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![BU of 1ycs by Molmil](/molmil-images/mine/1ycs) | P53-53BP2 COMPLEX | Descriptor: | 53BP2, P53, ZINC ION | Authors: | Gorina, S, Pavletich, N.P. | Deposit date: | 1996-09-30 | Release date: | 1997-11-19 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structure of the p53 tumor suppressor bound to the ankyrin and SH3 domains of 53BP2. Science, 274, 1996
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1YPH
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![BU of 1yph by Molmil](/molmil-images/mine/1yph) | High resolution structure of bovine alpha-chymotrypsin | Descriptor: | CHYMOTRYPSIN A, chain A, chain B, ... | Authors: | Razeto, A, Galunsky, B, Kasche, V, Wilson, K.S, Lamzin, V.S. | Deposit date: | 2005-01-31 | Release date: | 2006-02-14 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.34 Å) | Cite: | High resolution structure of native bovine alpha-chymotrypsin To be Published
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