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2X0J	2.8 A RESOLUTION STRUCTURE OF MALATE DEHYDROGENASE FROM ARCHAEOGLOBUS FULGIDUS IN COMPLEX WITH ETHENO-NAD Descriptor: ETHENO-NAD, MALATE DEHYDROGENASE, SULFATE ION Authors: Irimia, A, Madern, D, Zaccai, G, Vellieux, F.M, Karshikoff, A, Tibbelin, G, Ladenstein, R, Lien, T, Birkeland, N.K. Deposit date: 2009-12-14 Release date: 2009-12-22 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (2.786 Å) Cite: The 2.9A Resolution Crystal Structure of Malate Dehydrogenase from Archaeoglobus Fulgidus: Mechanisms of Oligomerisation and Thermal Stabilisation. J.Mol.Biol., 335, 2004
4JCO	1.7 A resolution structure of wild type malate dehydrogenase from haloarcula marismortui Descriptor: CHLORIDE ION, Malate dehydrogenase, SODIUM ION Authors: Vellieux, F.M.D. Deposit date: 2013-02-22 Release date: 2013-03-20 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (1.7 Å) Cite: 1.7 A resolution structure of wild type malate dehydrogenase from haloarcula marismortui To be Published
6IHE	Crystal structure of Malate dehydrogenase from Metallosphaera sedula Descriptor: 1,2-ETHANEDIOL, D-MALATE, DI(HYDROXYETHYL)ETHER, ... Authors: Lee, D, Kim, K.J. Deposit date: 2018-09-29 Release date: 2019-02-06 Last modified: 2024-03-27 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Crystal structure and biochemical characterization of malate dehydrogenase from Metallosphaera sedula Biochem. Biophys. Res. Commun., 509, 2019
6ITK	Crystal structure of malate dehydrogenase from Corynebacterium glutamicum ATCC 13032 in complex with NAD and malate Descriptor: (2S)-2-hydroxybutanedioic acid, Malate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE Authors: Seo, H, Kim, K.-J. Deposit date: 2018-11-23 Release date: 2019-11-27 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2 Å) Cite: Enhanced succinic acid production by Mannheimia employing optimal malate dehydrogenase. Nat Commun, 11, 2020
4KDF	Crystal Structure of Thermus thermophilus Malate Dehydrogenase in Complex with NAD Descriptor: Malate dehydrogenase, SULFATE ION Authors: Hsu, C.-H, Hong, C.-H, Chang, Y.-Y. Deposit date: 2013-04-25 Release date: 2014-02-05 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.356 Å) Cite: Crystal structures and molecular dynamics simulations of thermophilic malate dehydrogenase reveal critical loop motion for co-substrate binding. Plos One, 8, 2013
4L4S	Structural characterisation of the NADH binary complex of human lactate dehydrogenase M isozyme Descriptor: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, L-lactate dehydrogenase A chain Authors: Dempster, S, Harper, S, Moses, J.E, Dreveny, I. Deposit date: 2013-06-09 Release date: 2014-04-30 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Structural characterization of the apo form and NADH binary complex of human lactate dehydrogenase. Acta Crystallogr.,Sect.D, 70, 2014
6H9S	Crystal dimeric structure of Petrotoga mobilis lactate dehydrogenase with NADH Descriptor: L-lactate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE Authors: Roche, J, Engilberge, S, Girard, E, Madern, D. Deposit date: 2018-08-06 Release date: 2018-08-22 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Structure of Petrotoga mobilis lactate dehydrogenase at 1.9 Angstrom resolution To Be Published
6JML	Re-refined structure of R-state L-lactate dehydrogenase fromLactobacillus casei Descriptor: L-lactate dehydrogenase, SULFATE ION Authors: Arai, K, Miyanaga, A, Uchikoba, H, Fushinobu, S, Taguchi, H. Deposit date: 2019-03-12 Release date: 2020-05-06 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Crystal structure of penta mutant of L-lactate dehydrogenase from Lactobacillus casei To Be Published
4LN1	CRYSTAL STRUCTURE OF L-lactate dehydrogenase from Bacillus cereus ATCC 14579 complexed with calcium, NYSGRC Target 029452 Descriptor: CALCIUM ION, L-lactate dehydrogenase 1 Authors: Malashkevich, V.N, Bonanno, J.B, Bhosle, R, Toro, R, Hillerich, B, Gizzi, A, Garforth, S, Kar, A, Chan, M.K, Lafluer, J, Patel, H, Matikainen, B, Chamala, S, Lim, S, Celikgil, A, Villegas, G, Evans, B, Love, J, Fiser, A, Khafizov, K, Seidel, R, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC) Deposit date: 2013-07-11 Release date: 2013-07-24 Last modified: 2023-12-06 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Crystal structure of L-lactate dehydrogenase from Bacillus cereus ATCC 14579 complexed with calcium, NYSGRC Target 029452 To be Published
4LMR	Crystal structure of L-lactate dehydrogenase from Bacillus cereus ATCC 14579, NYSGRC Target 029452 Descriptor: L-lactate dehydrogenase 1 Authors: Malashkevich, V.N, Bonanno, J.B, Bhosle, R, Toro, R, Hillerich, B, Gizzi, A, Garforth, S, Kar, A, Chan, M.K, Lafluer, J, Patel, H, Matikainen, B, Chamala, S, Lim, S, Celikgil, A, Villegas, G, Evans, B, Love, J, Fiser, A, Khafizov, K, Seidel, R, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC) Deposit date: 2013-07-10 Release date: 2013-07-31 Last modified: 2023-12-06 Method: X-RAY DIFFRACTION (2.45 Å) Cite: Crystal structure of L-lactate dehydrogenase from Bacillus cereus ATCC 14579, NYSGRC Target 029452 To be Published
6K13	Crystal Structure Basis for BmLDH Complex Descriptor: L-lactate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, OXAMIC ACID Authors: Long, Y, Shen, Z. Deposit date: 2019-05-09 Release date: 2019-10-16 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (1.89 Å) Cite: Crystal structures ofBabesia microtilactate dehydrogenase BmLDH reveal a critical role for Arg99 in catalysis. Faseb J., 33, 2019
4L4R	Structural Characterisation of the Apo-form of Human Lactate Dehydrogenase M Isozyme Descriptor: L-lactate dehydrogenase A chain Authors: Dempster, S, Harper, S, Moses, J.E, Dreveny, I. Deposit date: 2013-06-09 Release date: 2014-04-30 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Structural characterization of the apo form and NADH binary complex of human lactate dehydrogenase. Acta Crystallogr.,Sect.D, 70, 2014
6ITL	Crystal structure of malate dehydrogenase from Mannheimia succiniciproducens in complex with NAD Descriptor: GLYCEROL, Malate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE Authors: Seo, H, Kim, K.-J. Deposit date: 2018-11-23 Release date: 2019-11-27 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (1.97 Å) Cite: Enhanced succinic acid production by Mannheimia employing optimal malate dehydrogenase. Nat Commun, 11, 2020
6KA0	Silver-bound E.coli Malate dehydrogenase Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Malate dehydrogenase, SILVER ION Authors: Wang, H, Wang, M, Sun, H. Deposit date: 2019-06-19 Release date: 2020-06-17 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.22 Å) Cite: MDH is a major silver target in E. coli To Be Published
6K12	Babesia microti lactate dehydrogenase apo form (BmLDH) Descriptor: L-lactate dehydrogenase Authors: Long, Y. Deposit date: 2019-05-09 Release date: 2019-10-16 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.794 Å) Cite: Crystal structures ofBabesia microtilactate dehydrogenase BmLDH reveal a critical role for Arg99 in catalysis. Faseb J., 33, 2019
6KA1	E.coli Malate dehydrogenase Descriptor: Malate dehydrogenase Authors: Wang, H, Wang, M, Sun, H. Deposit date: 2019-06-19 Release date: 2020-06-17 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (1.543 Å) Cite: MDH is a major silver target in E. coli To Be Published
4JNK	Lactate Dehydrogenase A in complex with inhibitor compound 22 Descriptor: (2R)-2-{[5-cyano-4-(3,4-dichlorophenyl)-6-oxo-1,6-dihydropyrimidin-2-yl]sulfanyl}-N-(4-sulfamoylphenyl)propanamide, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... Authors: Eigenbrot, C, Ultsch, M. Deposit date: 2013-03-15 Release date: 2013-05-22 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (1.896 Å) Cite: Identification of substituted 2-thio-6-oxo-1,6-dihydropyrimidines as inhibitors of human lactate dehydrogenase. Bioorg.Med.Chem.Lett., 23, 2013
4M1Q	Crystal structure of L-lactate dehydrogenase from Bacillus selenitireducens MLS10, NYSGRC Target 029814. Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, L-lactate dehydrogenase, PHOSPHATE ION Authors: Malashkevich, V.N, Bhosle, R, Toro, R, Hillerich, B, Gizzi, A, Garforth, S, Kar, A, Chan, M.K, Lafluer, J, Patel, H, Matikainen, B, Chamala, S, Lim, S, Celikgil, A, Villegas, G, Evans, B, Love, J, Fiser, A, Khafizov, K, Seidel, R, Bonanno, J.B, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC) Deposit date: 2013-08-03 Release date: 2013-08-21 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Crystal structure of L-lactate dehydrogenase from Bacillus selenitireducens MLS10, NYSGRC Target 029814. To be Published
6IHD	Crystal structure of Malate dehydrogenase from Metallosphaera sedula Descriptor: 2-ETHOXYETHANOL, Malate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE Authors: Lee, D, Kim, K.J. Deposit date: 2018-09-29 Release date: 2019-02-06 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Crystal structure and biochemical characterization of malate dehydrogenase from Metallosphaera sedula Biochem. Biophys. Res. Commun., 509, 2019
4KDE	Crystal Structure of the Apo Form of Thermus thermophilus Malate Dehydrogenase Descriptor: Malate dehydrogenase Authors: Hsu, C.-H, Hong, C.-H, Chang, Y.-Y. Deposit date: 2013-04-25 Release date: 2014-02-05 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.798 Å) Cite: Crystal structures and molecular dynamics simulations of thermophilic malate dehydrogenase reveal critical loop motion for co-substrate binding. Plos One, 8, 2013
6J9D	Babesia microti lactate dehydrogenase R99A (BmLDHR99A) Descriptor: L-lactate dehydrogenase Authors: Yu, L. Deposit date: 2019-01-22 Release date: 2019-10-16 Last modified: 2024-03-27 Method: X-RAY DIFFRACTION (2.904 Å) Cite: Crystal structures ofBabesia microtilactate dehydrogenase BmLDH reveal a critical role for Arg99 in catalysis. Faseb J., 33, 2019
4M49	Lactate Dehydrogenase A in complex with a substituted pyrazine inhibitor compound 18 Descriptor: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, 3-(5-amino-6-{[(1R)-1-phenylethyl]amino}pyrazin-2-yl)-4-chlorobenzoic acid, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... Authors: Eigenbrot, C, Ultsch, M. Deposit date: 2013-08-06 Release date: 2013-09-04 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (2.052 Å) Cite: Identification of 2-amino-5-aryl-pyrazines as inhibitors of human lactate dehydrogenase. Bioorg.Med.Chem.Lett., 23, 2013
4MDH	REFINED CRYSTAL STRUCTURE OF CYTOPLASMIC MALATE DEHYDROGENASE AT 2.5-ANGSTROMS RESOLUTION Descriptor: CYTOPLASMIC MALATE DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SULFATE ION Authors: Birktoft, J.J, Banaszak, L.J. Deposit date: 1989-04-12 Release date: 1989-04-19 Last modified: 2017-11-29 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Refined crystal structure of cytoplasmic malate dehydrogenase at 2.5-A resolution. Biochemistry, 28, 1989
6BB3	Lactate Dehydrogenase in complex with inhibitor 3-((2-chlorophenyl)thio)-6-(6-((4-fluorophenyl)amino)pyridin-2-yl)-4-hydroxy-6-(thiophen-3-yl)-5,6-dihydro-2H-pyran-2-one Descriptor: (6R)-3-[(2-chlorophenyl)sulfanyl]-6-{6-[(4-fluorophenyl)amino]pyridin-2-yl}-4-hydroxy-6-(thiophen-3-yl)-5,6-dihydro-2H-pyran-2-one, L-lactate dehydrogenase A chain, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... Authors: Chen, Z, Eigenbrot, C. Deposit date: 2017-10-16 Release date: 2018-10-24 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Structure-guided optimization and in vivo activities of hydroxylactone and hydroxylactam Inhibitors of Human Lactate Dehydrogenase To Be Published
6BB1	Lactate Dehydrogenase in complex with inhibitor (R)-5-((2-chlorophenyl)thio)-6'-(4-fluorophenoxy)-4-hydroxy-2-(thiophen-3-yl)-2,3-dihydro-[2,2'-bipyridin]-6(1H)-one Descriptor: (2R)-5-[(2-chlorophenyl)sulfanyl]-6'-(4-fluorophenoxy)-4-hydroxy-2-(thiophen-3-yl)-2,3-dihydro[2,2'-bipyridin]-6(1H)-one, L-lactate dehydrogenase A chain, LACTIC ACID, ... Authors: Ultsch, M, Eigenbrot, C. Deposit date: 2017-10-16 Release date: 2018-10-24 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Structure-guided optimization and in vivo activities of hydroxylactone and hydroxylactam Inhibitors of Human Lactate Dehydrogenase To Be Published

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