PDB: 5653 resultsInfo pagesStatus searchChemie searchBIRD

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5TX8	Solution structure of the de novo mini protein gHH_44 Descriptor: HH2 Authors: Buchko, G.W, Bahl, C.D, Baker, D. Deposit date: 2016-11-15 Release date: 2017-09-27 Last modified: 2023-06-14 Method: SOLUTION NMR Cite: Cytosolic expression, solution structures, and molecular dynamics simulation of genetically encodable disulfide-rich de novo designed peptides. Protein Sci., 27, 2018
8FBI	Improving the secretion of designed protein assemblies through negative design of cryptic transmembrane domains Descriptor: KWOCA_39 Authors: Wang, J.Y, Khmelinskaia, A, Bera, A.K, King, N.P. Deposit date: 2022-11-29 Release date: 2023-03-22 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (3.61 Å) Cite: Improving the secretion of designed protein assemblies through negative design of cryptic transmembrane domains. Proc.Natl.Acad.Sci.USA, 120, 2023
8FBK	Improving the secretion of designed protein assemblies through negative design of cryptic transmembrane domains Descriptor: KWOCA_65 Authors: Wang, J.Y, Khmelinskaia, A, Bera, A.K, King, N.P. Deposit date: 2022-11-29 Release date: 2023-03-22 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (3.15 Å) Cite: Improving the secretion of designed protein assemblies through negative design of cryptic transmembrane domains. Proc.Natl.Acad.Sci.USA, 120, 2023
2JWU	Solution NMR structures of two designed proteins with 88% sequence identity but different fold and function Descriptor: Gb88 Authors: He, Y, Chen, Y, Alexander, P, Bryan, P, Orban, J. Deposit date: 2007-10-25 Release date: 2008-09-09 Last modified: 2024-05-01 Method: SOLUTION NMR Cite: NMR structures of two designed proteins with high sequence identity but different fold and function Proc.Natl.Acad.Sci.Usa, 105, 2008
6Q5S	Crystal structure of a de novo designed antiparallel four-helix coiled coil apCC-Tet Descriptor: apCC-Tet Authors: Beesley, J.L, Guto, G.R, Wood, C.W, Brady, R.L, Woolfson, D.N. Deposit date: 2018-12-09 Release date: 2019-05-22 Last modified: 2019-06-19 Method: X-RAY DIFFRACTION (1.89 Å) Cite: Navigating the Structural Landscape of De Novo alpha-Helical Bundles. J.Am.Chem.Soc., 141, 2019
7OSV	DeNovoTIM6-SB, a de novo designed TIM barrel with a salt-bridge cluster (crystal form 1) Descriptor: ACETATE ION, DI(HYDROXYETHYL)ETHER, DeNovoTIM6-SB, ... Authors: Kordes, S, Romero-Romero, S, Hocker, B. Deposit date: 2021-06-09 Release date: 2021-12-15 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.66 Å) Cite: A newly introduced salt bridge cluster improves structural and biophysical properties of de novo TIM barrels. Protein Sci., 31, 2022
7P12	DeNovoTIM13-SB, a de novo designed TIM barrel with a salt-bridge cluster Descriptor: CHLORIDE ION, DeNovoTIM13-SB, PHOSPHATE ION Authors: Kordes, S, Romero-Romero, S, Hocker, B. Deposit date: 2021-07-01 Release date: 2021-12-15 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.69 Å) Cite: A newly introduced salt bridge cluster improves structural and biophysical properties of de novo TIM barrels. Protein Sci., 31, 2022
7OT8	DeNovoTIM6-SB, a de novo designed TIM barrel with a salt-bridge cluster (crystal form 2) Descriptor: DeNovoTIM6-SB, SULFATE ION Authors: Kordes, S, Romero-Romero, S, Hocker, B. Deposit date: 2021-06-09 Release date: 2021-12-15 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2.22 Å) Cite: A newly introduced salt bridge cluster improves structural and biophysical properties of de novo TIM barrels. Protein Sci., 31, 2022
5EZA	A de novo designed heptameric coiled coil CC-Hept-I18C-L22H Descriptor: CC-Hept-C-H-I, GLYCEROL Authors: Burton, A.J, Brady, R.L, Woolfson, D.N. Deposit date: 2015-11-26 Release date: 2016-07-06 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (1.76 Å) Cite: Installing hydrolytic activity into a completely de novo protein framework. Nat.Chem., 8, 2016
5EZE	A de novo designed heptameric coiled coil CC-Hept-I18betaMeCys-L22H-I25E Descriptor: CC-Hept-bMeCys-His-Glu, GLYCEROL Authors: Burton, A.J, Brady, R.L, Woolfson, D.N. Deposit date: 2015-11-26 Release date: 2016-07-06 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Installing hydrolytic activity into a completely de novo protein framework. Nat.Chem., 8, 2016
5EZ9	A de novo designed heptameric coiled coil CC-Hept-I-H-I Descriptor: CC-Hept-L22H, HEXANE-1,6-DIOL Authors: Burton, A.J, Brady, R.L, Woolfson, D.N. Deposit date: 2015-11-26 Release date: 2016-07-06 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Installing hydrolytic activity into a completely de novo protein framework. Nat.Chem., 8, 2016
5EZC	A de novo designed heptameric coiled coil CC-Hept-I18C-L22H-I25E Descriptor: CC-Hept-C-H-E Authors: Burton, A.J, Brady, R.L, Woolfson, D.N. Deposit date: 2015-11-26 Release date: 2016-07-06 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Installing hydrolytic activity into a completely de novo protein framework. Nat.Chem., 8, 2016
5F2Y	A de novo designed heptameric coiled coil CC-Hept-homoCys-H-E Descriptor: CC-Hept-hCys-H-E Authors: Burton, A.J, Brady, R.L, Woolfson, D.N. Deposit date: 2015-12-02 Release date: 2016-07-06 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Installing hydrolytic activity into a completely de novo protein framework. Nat.Chem., 8, 2016
7OSU	sTIM11noCys-SB, a de novo designed TIM barrel with a salt-bridge cluster (crystal form 1) Descriptor: CHLORIDE ION, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... Authors: Romero-Romero, S, Kordes, S, Hocker, B. Deposit date: 2021-06-09 Release date: 2021-12-15 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.37 Å) Cite: A newly introduced salt bridge cluster improves structural and biophysical properties of de novo TIM barrels. Protein Sci., 31, 2022
7OT7	sTIM11noCys-SB, a de novo designed TIM barrel with a salt-bridge cluster (crystal form 2) Descriptor: sTIM11noCys-SB Authors: Romero-Romero, S, Kordes, S, Hocker, B. Deposit date: 2021-06-09 Release date: 2021-12-15 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.51 Å) Cite: A newly introduced salt bridge cluster improves structural and biophysical properties of de novo TIM barrels. Protein Sci., 31, 2022
5EZ8	A de novo designed heptameric coiled coil CC-Hept-I-C-I Descriptor: CC-Hept-I-C-I Authors: Burton, A.J, Brady, R.L, Woolfson, D.N. Deposit date: 2015-11-26 Release date: 2016-07-06 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Installing hydrolytic activity into a completely de novo protein framework. Nat.Chem., 8, 2016
5EON	Crystal structure of a de novo antiparallel coiled-coil hexamer - ACC-Hex Descriptor: ACC-Hex Authors: Spencer, R.K, Hochbaum, A.I. Deposit date: 2015-11-10 Release date: 2016-05-25 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (1.696 Å) Cite: X-ray Crystallographic Structure and Solution Behavior of an Antiparallel Coiled-Coil Hexamer Formed by de Novo Peptides. Biochemistry, 55, 2016
7NFJ	A heptameric barrel state of a de novo coiled-coil assembly: CC-Type2-(LaId)4-L28Y. Descriptor: CC-Type2-(LaId)4-L28Y Authors: Rhys, G.G, Dawson, W.M, Brady, R.L, Woolfson, D.N. Deposit date: 2021-02-07 Release date: 2022-03-02 Last modified: 2024-05-01 Method: X-RAY DIFFRACTION (1.19 Å) Cite: Differential sensing with arrays of de novo designed peptide assemblies. Nat Commun, 14, 2023
7NFL	An octameric barrel state of a de novo coiled-coil assembly: CC-Type2-(LaId)4-I24N. Descriptor: CC-Type2-(LaId)4-I24N Authors: Rhys, G.G, Dawson, W.M, Brady, R.L, Woolfson, D.N. Deposit date: 2021-02-07 Release date: 2022-03-02 Last modified: 2024-05-01 Method: X-RAY DIFFRACTION (1.44 Å) Cite: Differential sensing with arrays of de novo designed peptide assemblies. Nat Commun, 14, 2023
7NFO	A hexameric barrel state of a de novo coiled-coil assembly: CC-Type2-(LaId)4-I17C. Descriptor: CC-Type2-(LaId)4-I17C Authors: Rhys, G.G, Dawson, W.M, Brady, R.L, Woolfson, D.N. Deposit date: 2021-02-07 Release date: 2022-03-02 Last modified: 2024-05-01 Method: X-RAY DIFFRACTION (1.37 Å) Cite: Differential sensing with arrays of de novo designed peptide assemblies. Nat Commun, 14, 2023
7NFF	An octameric barrel state of a de novo coiled-coil assembly: CC-Type2-(LaId)4-I24A. Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CC-Type2-(LaId)4-I24A, GLYCEROL Authors: Rhys, G.G, Dawson, W.M, Brady, R.L, Woolfson, D.N. Deposit date: 2021-02-07 Release date: 2022-03-02 Last modified: 2024-05-01 Method: X-RAY DIFFRACTION (1.55 Å) Cite: Differential sensing with arrays of de novo designed peptide assemblies. Nat Commun, 14, 2023
7NFM	An octameric barrel state of a de novo coiled-coil assembly: CC-Type2-(LaId)4-L21K. Descriptor: CC-Type2-(LaId)4-L21K Authors: Rhys, G.G, Dawson, W.M, Brady, R.L, Woolfson, D.N. Deposit date: 2021-02-07 Release date: 2022-03-02 Last modified: 2024-05-01 Method: X-RAY DIFFRACTION (1.45 Å) Cite: Differential sensing with arrays of de novo designed peptide assemblies. Nat Commun, 14, 2023
7NFI	An octameric barrel state of a de novo coiled-coil assembly: CC-Type2-(LaId)4-L7Y. Descriptor: CC-Type2-(LaId)4-L7Y Authors: Rhys, G.G, Dawson, W.M, Brady, R.L, Woolfson, D.N. Deposit date: 2021-02-07 Release date: 2022-03-02 Last modified: 2024-05-01 Method: X-RAY DIFFRACTION (1.42 Å) Cite: Differential sensing with arrays of de novo designed peptide assemblies. Nat Commun, 14, 2023
7NFP	A heptameric barrel state of a de novo coiled-coil assembly: CC-Type2-(LaId)4-I17K Descriptor: CC-Type2-(LaId)4-I17K, GLYCEROL Authors: Burton, A.J, Rhys, G.G, Dawson, W.M, Brady, R.L, Woolfson, D.N. Deposit date: 2021-02-07 Release date: 2022-03-02 Last modified: 2024-05-01 Method: X-RAY DIFFRACTION (1.43 Å) Cite: Differential sensing with arrays of de novo designed peptide assemblies. Nat Commun, 14, 2023
7NFK	An octameric barrel state of a de novo coiled-coil assembly: CC-Type2-(LaId)4-I24S. Descriptor: CC-Type2-(LaId)4-I24S, ISOPROPYL ALCOHOL Authors: Rhys, G.G, Dawson, W.M, Brady, R.L, Woolfson, D.N. Deposit date: 2021-02-07 Release date: 2022-03-02 Last modified: 2024-05-01 Method: X-RAY DIFFRACTION (1.3 Å) Cite: Differential sensing with arrays of de novo designed peptide assemblies. Nat Commun, 14, 2023

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