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7B66
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BU of 7b66 by Molmil
Structure of NUDT15 R139H Mutant in complex with TH7755
Descriptor: (R)-6-((2-methyl-4-(1-methyl-1H-indole-5-carbonyl)piperazin-1-yl)sulfonyl)benzo[d]oxazol-2(3H)-one, Nucleotide triphosphate diphosphatase NUDT15
Authors:Rehling, D, Stenmark, P.
Deposit date:2020-12-07
Release date:2021-03-24
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystal structures of NUDT15 variants enabled by a potent inhibitor reveal the structural basis for thiopurine sensitivity.
J.Biol.Chem., 296, 2021
7B64
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BU of 7b64 by Molmil
Structure of NUDT15 V18I Mutant in complex with TH7755
Descriptor: (R)-6-((2-methyl-4-(1-methyl-1H-indole-5-carbonyl)piperazin-1-yl)sulfonyl)benzo[d]oxazol-2(3H)-one, Nucleotide triphosphate diphosphatase NUDT15
Authors:Rehling, D, Stenmark, P.
Deposit date:2020-12-07
Release date:2021-03-24
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Crystal structures of NUDT15 variants enabled by a potent inhibitor reveal the structural basis for thiopurine sensitivity.
J.Biol.Chem., 296, 2021
1U1P
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BU of 1u1p by Molmil
Crystal Structure of UP1 Complexed With d(TTAGGGTTA 2PR GG); A Human Telomeric Repeat Containing 2-aminopurine
Descriptor: 5'-D(*T*TP*AP*GP*GP*GP*TP*TP*AP*(2PR)P*GP*G)-3', Heterogeneous nuclear ribonucleoprotein A1
Authors:Myers, J.C, Shamoo, Y.
Deposit date:2004-07-15
Release date:2004-09-21
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Human UP1 as a Model for Understanding Purine Recognition in the Family of Proteins Containing the RNA Recognition Motif (RRM).
J.Mol.Biol., 342, 2004
1U1L
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Crystal Structure of UP1 Complexed With d(TTAGGGTT PRN GGG); A Human Telomeric Repeat Containing nebularine
Descriptor: 5'-D(*TP*AP*GP*GP*GP*TP*TP*(PRN)P*GP*GP*G)-3', Heterogeneous nuclear ribonucleoprotein A1
Authors:Myers, J.C, Shamoo, Y.
Deposit date:2004-07-15
Release date:2004-09-21
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2 Å)
Cite:Human UP1 as a Model for Understanding Purine Recognition in the Family of Proteins Containing the RNA Recognition Motif (RRM).
J.Mol.Biol., 342, 2004
1U1O
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BU of 1u1o by Molmil
Crystal Structure of UP1 Complexed With d(TTAGGGTTAG(DI)G); A Human Telomeric Repeat Containing Inosine
Descriptor: 5'-D(*TP*AP*GP*GP*GP*TP*TP*AP*GP*(OIP)*G)-3', Heterogeneous nuclear ribonucleoprotein A1
Authors:Myers, J.C, Shamoo, Y.
Deposit date:2004-07-15
Release date:2004-09-21
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2 Å)
Cite:Human UP1 as a Model for Understanding Purine Recognition in the Family of Proteins Containing the RNA Recognition Motif (RRM).
J.Mol.Biol., 342, 2004
1U1M
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BU of 1u1m by Molmil
Crystal Structure of UP1 Complexed With d(TTAGGGTTA 7GU GG); A Human Telomeric Repeat Containing 7-deaza-guanine
Descriptor: 5'-D(*TP*AP*GP*GP*GP*TP*TP*AP*(7GU)P*GP*G)-3', Heterogeneous nuclear ribonucleoprotein A1
Authors:Myers, J.C, Shamoo, Y.
Deposit date:2004-07-15
Release date:2004-09-21
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2 Å)
Cite:Human UP1 as a Model for Understanding Purine Recognition in the Family of Proteins Containing the RNA Recognition Motif (RRM).
J.Mol.Biol., 342, 2004
1U1R
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BU of 1u1r by Molmil
Crystal Structure of UP1 Complexed With d(TTAGGGTTAG(2PR)G); A Human Telomeric Repeat Containing 2-aminopurine
Descriptor: 5'-D(*TP*AP*GP*GP*GP*TP*TP*AP*GP*(2PR)P*G)-3', Heterogeneous nuclear ribonucleoprotein A1
Authors:Myers, J.C, Shamoo, Y.
Deposit date:2004-07-15
Release date:2004-09-21
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Human UP1 as a Model for Understanding Purine Recognition in the Family of Proteins Containing the RNA Recognition Motif (RRM).
J.Mol.Biol., 342, 2004
2IJG
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BU of 2ijg by Molmil
Crystal Structure of cryptochrome 3 from Arabidopsis thaliana
Descriptor: 5,10-METHENYL-6,7,8-TRIHYDROFOLIC ACID, Cryptochrome DASH, chloroplast/mitochondrial, ...
Authors:Huang, Y, Deisenhofer, J.
Deposit date:2006-09-29
Release date:2006-11-28
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of cryptochrome 3 from Arabidopsis thaliana and its implications for photolyase activity
Proc.Natl.Acad.Sci.Usa, 103, 2006
7BP4
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BU of 7bp4 by Molmil
Structural insights into nucleosome reorganization by NAP1-RELATED PROTEIN 1 (NRP1)
Descriptor: ASP-ASP-ASP-ASP-TYR, GLYCEROL, Histone H2A.6, ...
Authors:Luo, Q, Baihui, W.
Deposit date:2020-03-21
Release date:2020-11-11
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:NAP1-Related Protein 1 (NRP1) has multiple interaction modes for chaperoning histones H2A-H2B.
Proc.Natl.Acad.Sci.USA, 117, 2020
7BP6
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BU of 7bp6 by Molmil
Structural insights into nucleosome reorganization by NAP1-RELATED PROTEIN 1 (NRP1)
Descriptor: Histone H2A.6, Histone H2B.1, NRP1-CTAD
Authors:Luo, Q, Baihui, W.
Deposit date:2020-03-21
Release date:2020-11-11
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (1.58 Å)
Cite:NAP1-Related Protein 1 (NRP1) has multiple interaction modes for chaperoning histones H2A-H2B.
Proc.Natl.Acad.Sci.USA, 117, 2020
7BR8
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BU of 7br8 by Molmil
Epstein-Barr virus, C5 penton vertex, CATC absent.
Descriptor: Major capsid protein, Small capsomere-interacting protein, Triplex capsid protein 1, ...
Authors:Li, Z, Yu, X.
Deposit date:2020-03-26
Release date:2020-09-30
Last modified:2024-10-09
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:CryoEM structure of the tegumented capsid of Epstein-Barr virus.
Cell Res., 30, 2020
1S47
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BU of 1s47 by Molmil
Crystal structure analysis of the DNA quadruplex d(TGGGGT)S2
Descriptor: 5'-D(*TP*GP*GP*GP*GP*T)-3', SODIUM ION, THALLIUM (I) ION
Authors:Caceres, C, Wright, G, Gouyette, C, Parkinson, G, Subirana, J.A.
Deposit date:2004-01-15
Release date:2004-02-24
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:A Thymine tetrad in d(TGGGGT) quadruplexes stabilized with Tl+1/Na+1 ions
Nucleic Acids Res., 32, 2004
4O61
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BU of 4o61 by Molmil
Structure of human ALKBH5 crystallized in the presence of citrate
Descriptor: CITRIC ACID, GLYCEROL, RNA demethylase ALKBH5, ...
Authors:Tempel, W, Chao, X, Liu, K, Dong, A, Cerovina, T, He, H, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
Deposit date:2013-12-20
Release date:2014-02-26
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structures of human ALKBH5 demethylase reveal a unique binding mode for specific single-stranded N6-methyladenosine RNA demethylation.
J.Biol.Chem., 289, 2014
7BP2
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BU of 7bp2 by Molmil
Structural mechanism directing nucleosome reorganization by NAP1-RELATED PROTEIN 1 (NRP1)
Descriptor: GLYCEROL, Histone H2A.6, Histone H2B.1, ...
Authors:Luo, Q, Baihui, W.
Deposit date:2020-03-21
Release date:2020-11-11
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.58 Å)
Cite:NAP1-Related Protein 1 (NRP1) has multiple interaction modes for chaperoning histones H2A-H2B.
Proc.Natl.Acad.Sci.USA, 117, 2020
7BSI
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BU of 7bsi by Molmil
Epstein-Barr virus, one asymmetric unit structure of the icosahedral tegumented capsid
Descriptor: Major capsid protein, Small capsomere-interacting protein, Triplex capsid protein 1, ...
Authors:Li, Z, Yu, X.
Deposit date:2020-03-30
Release date:2020-09-30
Last modified:2020-10-14
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:CryoEM structure of the tegumented capsid of Epstein-Barr virus.
Cell Res., 30, 2020
7BP5
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BU of 7bp5 by Molmil
Structural insights into nucleosome reorganization by NAP1-RELATED PROTEIN 1 (NRP1)
Descriptor: ASN-ASP-PRO-ASP-TYR, GLYCEROL, Histone H2A.6, ...
Authors:Luo, Q, Baihui, W.
Deposit date:2020-03-21
Release date:2020-11-11
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:NAP1-Related Protein 1 (NRP1) has multiple interaction modes for chaperoning histones H2A-H2B.
Proc.Natl.Acad.Sci.USA, 117, 2020
7BQX
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BU of 7bqx by Molmil
Epstein-Barr virus, C5 portal vertex
Descriptor: Capsid vertex component 1, Capsid vertex component 2, Large tegument protein deneddylase, ...
Authors:Li, Z, Yu, X.
Deposit date:2020-03-25
Release date:2020-09-30
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:CryoEM structure of the tegumented capsid of Epstein-Barr virus.
Cell Res., 30, 2020
7BR7
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BU of 7br7 by Molmil
Epstein-Barr virus, C1 portal-proximal penton vertex, CATC binding
Descriptor: Capsid vertex component 1, Capsid vertex component 2, Large tegument protein deneddylase, ...
Authors:Li, Z, Yu, X.
Deposit date:2020-03-26
Release date:2020-09-30
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:CryoEM structure of the tegumented capsid of Epstein-Barr virus.
Cell Res., 30, 2020
2WC9
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BU of 2wc9 by Molmil
Crystal structure of the g2p (large terminase) nuclease domain from the bacteriophage SPP1 with bound Mn
Descriptor: MANGANESE (II) ION, SULFATE ION, TERMINASE LARGE SUBUNIT
Authors:Smits, C, Chechik, M, Kovalevskiy, O.V, Shevtsov, M.B, Foster, A.W, Alonso, J.C, Antson, A.A.
Deposit date:2009-03-10
Release date:2009-03-24
Last modified:2017-06-28
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural Basis for the Nuclease Activity of a Bacteriophage Large Terminase.
Embo Rep., 10, 2009
2K29
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BU of 2k29 by Molmil
Structure of the DBD domain of E. coli antitoxin RelB
Descriptor: Antitoxin RelB
Authors:Li, G, Zhang, Y, Inouye, M, Ikura, M.
Deposit date:2008-03-28
Release date:2008-04-22
Last modified:2024-05-08
Method:SOLUTION NMR
Cite:Structural mechanism of transcriptional autorepression of the Escherichia coli RelB/RelE antitoxin/toxin module.
J.Mol.Biol., 380, 2008
5DGV
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BU of 5dgv by Molmil
Complex of yeast 80S ribosome with hypusine-containing/non-modified eIF5A and/or a peptidyl-tRNA analog
Descriptor: 25S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ...
Authors:Melnikov, S, Mailliot, J, Shin, B.-S, Rigger, L, Yusupova, G, Micura, R, Dever, T.E, Yusupov, M.
Deposit date:2015-08-28
Release date:2016-12-14
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Coping with proline stalling: structural basis of hypusine-induced protein synthesis by the eukaryotic ribosome
To Be Published
6YIH
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BU of 6yih by Molmil
Structure of Chromosomal Passenger Complex (CPC) bound to phosphorylated Histone 3 peptide at 2.6 A.
Descriptor: Baculoviral IAP repeat-containing protein 5, Borealin, Histone H3.1, ...
Authors:Serena, M, Elliott, P.R, Barr, F.A.
Deposit date:2020-04-01
Release date:2020-05-13
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Molecular basis of MKLP2-dependent Aurora B transport from chromatin to the anaphase central spindle.
J.Cell Biol., 219, 2020
4OCT
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BU of 4oct by Molmil
Crystal structure of human ALKBH5 crystallized in the presence of Mn^{2+} and 2-oxoglutarate
Descriptor: 2-OXOGLUTARIC ACID, MANGANESE (II) ION, RNA demethylase ALKBH5, ...
Authors:Tempel, W, Chao, X, Liu, K, Dong, A, Cerovina, T, He, H, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
Deposit date:2014-01-09
Release date:2014-04-16
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:Structures of human ALKBH5 demethylase reveal a unique binding mode for specific single-stranded N6-methyladenosine RNA demethylation.
J.Biol.Chem., 289, 2014
4ADZ
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BU of 4adz by Molmil
Crystal Structure of the apo form of a Copper-sensitive operon Regulator (CsoR) protein from Streptomyces lividans
Descriptor: CSOR, SULFATE ION
Authors:Dwarakanath, S, Hough, M.A, Worrall, J.A.R.
Deposit date:2012-01-04
Release date:2012-04-25
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:The Response to Copper Stress in Streptomyces Lividans Extends Beyond Genes Under the Direct Control of a Copper Sensitive Operon Repressor Protein (Csor)
J.Biol.Chem., 287, 2012
5ZQY
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BU of 5zqy by Molmil
Crystal structure of a poly(ADP-ribose) glycohydrolase
Descriptor: MAGNESIUM ION, Poly(ADP-ribose) glycohydrolase ARH3, [(2R,3S,4R,5R)-5-(6-AMINOPURIN-9-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHYL [HYDROXY-[[(2R,3S,4R,5S)-3,4,5-TRIHYDROXYOXOLAN-2-YL]METHOXY]PHOSPHORYL] HYDROGEN PHOSPHATE
Authors:Wang, M, Yuan, Z, Ma, Y, Wang, J, Liu, X.
Deposit date:2018-04-20
Release date:2018-08-15
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.577 Å)
Cite:Structure-function analyses reveal the mechanism of the ARH3-dependent hydrolysis of ADP-ribosylation.
J. Biol. Chem., 293, 2018

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數據於2024-10-09公開中

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