5ZQY

Crystal structure of a poly(ADP-ribose) glycohydrolase

Summary for 5ZQY

• Entry DOI: 10.2210/pdb5zqy/pdb
• Descriptor: Poly(ADP-ribose) glycohydrolase ARH3, MAGNESIUM ION, [(2R,3S,4R,5R)-5-(6-AMINOPURIN-9-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHYL [HYDROXY-[[(2R,3S,4R,5S)-3,4,5-TRIHYDROXYOXOLAN-2-YL]METHOXY]PHOSPHORYL] HYDROGEN PHOSPHATE, ... (4 entities in total)
• Functional Keywords: poly(adp-ribose) glycohydrolase, lyase, hydrolase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 38462.22

Authors

Wang, M.,Yuan, Z.,Ma, Y.,Wang, J.,Liu, X. (deposition date: 2018-04-20, release date: 2018-08-15, Last modification date: 2023-11-22)

• Primary citation: Wang, M.,Yuan, Z.,Xie, R.,Ma, Y.,Liu, X.,Yu, X.; Structure-function analyses reveal the mechanism of the ARH3-dependent hydrolysis of ADP-ribosylation.; J. Biol. Chem., 293:14470-14480, 2018; PubMed: 30045870; DOI: 10.1074/jbc.RA118.004284

Experimental method

X-RAY DIFFRACTION (1.577 Å)