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3JVI
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BU of 3jvi by Molmil
Product state mimic crystal structure of protein tyrosine phosphatase from Entamoeba histolytica
Descriptor: Protein tyrosine phosphatase, SULFATE ION
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2009-09-16
Release date:2009-09-22
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure and putative substrate identification for the Entamoeba histolytica low molecular weight tyrosine phosphatase.
Mol.Biochem.Parasitol., 193, 2014
3JWH
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BU of 3jwh by Molmil
Crystal structure analysis of the methyltransferase domain of bacterial-AvHen1-C
Descriptor: Hen1, S-ADENOSYL-L-HOMOCYSTEINE
Authors:Huang, R.H, Chan, C.M, Zhou, C, Brunzelle, J.S.
Deposit date:2009-09-18
Release date:2009-10-20
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural and biochemical insights into 2'-O-methylation at the 3'-terminal nucleotide of RNA by Hen1.
Proc.Natl.Acad.Sci.USA, 106, 2009
6ZZF
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BU of 6zzf by Molmil
Structure of the cis-(Tyr39-Pro40) form of the Human Secreted Ly-6/uPAR Related Protein-1 (SLURP-1)
Descriptor: Secreted Ly-6/uPAR-related protein 1
Authors:Paramonov, A.S, Lyukmanova, E.N, Shenkarev, Z.O.
Deposit date:2020-08-04
Release date:2021-01-13
Last modified:2024-11-20
Method:SOLUTION NMR
Cite:Structural Diversity and Dynamics of Human Three-Finger Proteins Acting on Nicotinic Acetylcholine Receptors.
Int J Mol Sci, 21, 2020
3JXF
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BU of 3jxf by Molmil
CA-like domain of human PTPRZ
Descriptor: Receptor-type tyrosine-protein phosphatase zeta
Authors:Bouyain, S.
Deposit date:2009-09-19
Release date:2009-12-22
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.004 Å)
Cite:The protein tyrosine phosphatases PTPRZ and PTPRG bind to distinct members of the contactin family of neural recognition molecules.
Proc.Natl.Acad.Sci.USA, 107, 2010
6ZN8
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BU of 6zn8 by Molmil
Crystal structure of the H. influenzae VapXD toxin-antitoxin complex
Descriptor: Endoribonuclease VapD, VapX
Authors:Bertelsen, M.B, Senissar, M, Nielsen, M.H, Bisiak, F, Cunha, M.V, Molinaro, A.L, Daines, D.A, Brodersen, D.E.
Deposit date:2020-07-06
Release date:2020-11-04
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (3.211 Å)
Cite:Structural Basis for Toxin Inhibition in the VapXD Toxin-Antitoxin System.
Structure, 29, 2021
3K2D
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BU of 3k2d by Molmil
Crystal structure of Immunogenic lipoprotein A from Vibrio vulnificus
Descriptor: ABC-type metal ion transport system, periplasmic component, METHIONINE
Authors:Yu, S, Rhee, S.
Deposit date:2009-09-30
Release date:2010-10-13
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structure of Toll-like receptor 2-activating lipoprotein IIpA from Vibrio vulnificus.
Proteins, 79, 2011
3K2M
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BU of 3k2m by Molmil
Crystal Structure of Monobody HA4/Abl1 SH2 Domain Complex
Descriptor: Monobody HA4, PHOSPHATE ION, Proto-oncogene tyrosine-protein kinase ABL1
Authors:Wojcik, J.B, Duguid, E.
Deposit date:2009-09-30
Release date:2010-03-31
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:A potent and highly specific FN3 monobody inhibitor of the Abl SH2 domain.
Nat.Struct.Mol.Biol., 17, 2010
3K4U
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BU of 3k4u by Molmil
CRYSTAL STRUCTURE OF putative binding component of ABC transporter from Wolinella succinogenes DSM 1740 complexed with lysine
Descriptor: BINDING COMPONENT OF ABC TRANSPORTER, LYSINE
Authors:Malashkevich, V.N, Toro, R, Morano, C, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2009-10-06
Release date:2009-11-03
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (2.62 Å)
Cite:CRYSTAL STRUCTURE OF putative binding component of ABC transporter from Wolinella succinogenes DSM 1740 complexed with lysine
To be Published
6ZXV
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BU of 6zxv by Molmil
Structure of Archaeoglobus fulgidus Trm11 m2G10 tRNA methyltransferase enzyme bound to sinefungin
Descriptor: 1,2-ETHANEDIOL, SINEFUNGIN, tRNA (Guanine(10)-N2)-dimethyltransferase
Authors:Graille, M, Wang, C.
Deposit date:2020-07-30
Release date:2020-09-23
Last modified:2024-05-15
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:Functional and structural characterization of the Trm11-Trm112 m2G10 tRNA methyltransferase complex
Nucleic Acids Res., 2020
6ZXY
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BU of 6zxy by Molmil
Structure of Archaeoglobus fulgidus Trm11 m2G10 tRNA methyltransferase enzyme
Descriptor: 1,2-ETHANEDIOL, tRNA (Guanine(10)-N2)-dimethyltransferase
Authors:Graille, M, Wang, C.
Deposit date:2020-07-30
Release date:2020-09-23
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Functional and structural characterization of the Trm11-Trm112 m2G10 tRNA methyltransferase complex
Nucleic Acids Res.
3JR1
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BU of 3jr1 by Molmil
Crystal structure of Putative fructosamine-3-kinase (YP_719053.1) from HAEMOPHILUS SOMNUS 129PT at 2.32 A resolution
Descriptor: 1,2-ETHANEDIOL, Putative fructosamine-3-kinase, UNKNOWN LIGAND
Authors:Joint Center for Structural Genomics (JCSG)
Deposit date:2009-09-08
Release date:2009-09-15
Last modified:2024-11-27
Method:X-RAY DIFFRACTION (2.32 Å)
Cite:Crystal structure of Putative fructosamine-3-kinase (YP_719053.1) from HAEMOPHILUS SOMNUS 129PT at 2.32 A resolution
To be published
3JRA
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BU of 3jra by Molmil
Crystal structure of Fis bound to 27bp non consensus sequence DNA F6
Descriptor: DNA (27-MER), DNA-binding protein fis
Authors:Stella, S, Cascio, D, Johnson, R.C.
Deposit date:2009-09-08
Release date:2010-04-28
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (3.11 Å)
Cite:The shape of the DNA minor groove directs binding by the DNA-bending protein Fis.
Genes Dev., 24, 2010
7A14
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BU of 7a14 by Molmil
CRYSTAL STRUCTURE OF HUMAN METHIONINE AMINOPEPTIDASE-2 IN COMPLEX WITH AN INHIBITOR GSK2218325A (COMPOUND 32)
Descriptor: 5-chloranyl-6-fluoranyl-3-(2-propan-2-yloxyphenyl)-1~{H}-indole-2-carboxamide, MANGANESE (II) ION, Methionine aminopeptidase 2, ...
Authors:Thorpe, J.H.
Deposit date:2020-08-11
Release date:2020-09-23
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (2.14 Å)
Cite:Structure-based optimisation of orally active & reversible MetAP-2 inhibitors maintaining a tight 'molecular budget'.
Bioorg.Med.Chem.Lett., 30, 2020
3JVH
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BU of 3jvh by Molmil
Crystal structure of 2C-methyl-D-erythritol-2,4-cyclodiphosphate synthase from Burkholderia pseudomallei with FOL fragment 8395
Descriptor: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, 5-[(pyridin-3-ylmethyl)amino]-1H-pyrazole-4-carboxamide, GLYCEROL, ...
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2009-09-16
Release date:2009-09-29
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.69 Å)
Cite:Leveraging structure determination with fragment screening for infectious disease drug targets: MECP synthase from Burkholderia pseudomallei.
J Struct Funct Genomics, 12, 2011
3J45
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BU of 3j45 by Molmil
Structure of a non-translocating SecY protein channel with the 70S ribosome
Descriptor: 23S ribosomal RNA, 50S ribosomal protein L23, 50S ribosomal protein L24, ...
Authors:Menetret, J.F, Park, E, Gumbart, J.C, Ludtke, S.J, Li, W, Whynot, A, Rapoport, T.A, Akey, C.W.
Deposit date:2013-06-18
Release date:2013-10-23
Last modified:2024-11-27
Method:ELECTRON MICROSCOPY (9.5 Å)
Cite:Structure of the SecY channel during initiation of protein translocation.
Nature, 506, 2013
6ZQI
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BU of 6zqi by Molmil
Cryo-EM structure of Spondweni virus prME
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Genome polyprotein
Authors:Renner, M, Dejnirattisai, W, Carrique, L, Serna Martin, I, Karia, D, Ilca, S.L, Ho, S.F, Kotecha, A, Keown, J.R, Mongkolsapaya, J, Screaton, G.R, Grimes, J.M.
Deposit date:2020-07-09
Release date:2021-01-20
Last modified:2024-11-06
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Flavivirus maturation leads to the formation of an occupied lipid pocket in the surface glycoproteins.
Nat Commun, 12, 2021
3JW4
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BU of 3jw4 by Molmil
The structure of a putative MarR family transcriptional regulator from Clostridium acetobutylicum
Descriptor: GLYCEROL, IMIDAZOLE, POTASSIUM ION, ...
Authors:Cuff, M.E, Bigelow, L, Moy, S, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
Deposit date:2009-09-17
Release date:2009-12-22
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The structure of a putative MarR family transcriptional regulator from Clostridium acetobutylicum
TO BE PUBLISHED
3JWP
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BU of 3jwp by Molmil
Crystal structure of Plasmodium falciparum SIR2A (PF13_0152) in complex with AMP
Descriptor: ADENOSINE MONOPHOSPHATE, TRIETHYLENE GLYCOL, Transcriptional regulatory protein sir2 homologue, ...
Authors:Wernimont, A.K, Hutchinson, A, Lin, Y.H, MacKenzie, F, Senisterra, G, Allali-Hassanali, A, Vedadi, M, Ravichandran, M, Cossar, D, Kozieradzki, I, Zhao, Y, Schapira, M, Arrowsmith, C.H, Bountra, C, Weigelt, J, Edwards, A.M, Hui, R, Qiu, W, Brand, V, Structural Genomics Consortium (SGC)
Deposit date:2009-09-18
Release date:2009-10-20
Last modified:2024-11-27
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Crystal structure of Plasmodium falciparum SIR2A (PF13_0152) in complex with AMP
TO BE PUBLISHED
6ZU8
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BU of 6zu8 by Molmil
Crystal structure of human Brachyury G177D variant in complex with Afatinib
Descriptor: Brachyury protein, N-{4-[(3-chloro-4-fluorophenyl)amino]-7-[(3S)-tetrahydrofuran-3-yloxy]quinazolin-6-yl}-4-(dimethylamino)butanamide, ZINC ION
Authors:Newman, J.A, Gavard, A.E, Shrestha, L, Burgess-Brown, N.A, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O.
Deposit date:2020-07-21
Release date:2020-08-05
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Crystal structure of human Brachyury G177D variant in complex with Afatinib
To Be Published
3JZT
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BU of 3jzt by Molmil
Structure of a cubic crystal form of X (ADRP) domain from FCoV with ADP-ribose
Descriptor: ADENOSINE-5-DIPHOSPHORIBOSE, CHLORIDE ION, SODIUM ION, ...
Authors:Wojdyla, J.A, Manolaridis, I, Tucker, P.A.
Deposit date:2009-09-24
Release date:2010-01-12
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (3.91 Å)
Cite:Structure of the X (ADRP) domain of nsp3 from feline coronavirus
Acta Crystallogr.,Sect.D, 65, 2009
3K0I
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BU of 3k0i by Molmil
Crystal structure of Cu(I)CusA
Descriptor: COPPER (I) ION, Cation efflux system protein cusA
Authors:Su, C.-C.
Deposit date:2009-09-24
Release date:2010-10-13
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (4.116 Å)
Cite:Crystal structure of CusA
To be Published
7A12
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BU of 7a12 by Molmil
CRYSTAL STRUCTURE OF HUMAN METHIONINE AMINOPEPTIDASE-2 IN COMPLEX WITH AN INHIBITOR GW557358X (COMPOUND 9)
Descriptor: 5-chloranyl-3-phenyl-1~{H}-indole-2-carboxamide, MANGANESE (II) ION, Methionine aminopeptidase 2, ...
Authors:Thorpe, J.H.
Deposit date:2020-08-11
Release date:2020-09-23
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure-based optimisation of orally active & reversible MetAP-2 inhibitors maintaining a tight 'molecular budget'.
Bioorg.Med.Chem.Lett., 30, 2020
6ZYV
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BU of 6zyv by Molmil
Structure of a Plasmodium PIR protein ectodomain
Descriptor: CIR protein
Authors:Harrison, T.E, Higgins, M.K.
Deposit date:2020-08-03
Release date:2020-11-25
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structure of the Plasmodium -interspersed repeat proteins of the malaria parasite.
Proc.Natl.Acad.Sci.USA, 117, 2020
7A3M
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BU of 7a3m by Molmil
Synergistic stabilization of a double mutant in CI2 from an in-cell library screen
Descriptor: Subtilisin-chymotrypsin inhibitor-2A
Authors:Olsen, J.G, Teilum, K, Hamborg, L, Roche, J.V.
Deposit date:2020-08-18
Release date:2020-12-09
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.01 Å)
Cite:Synergistic stabilization of a double mutant in chymotrypsin inhibitor 2 from a library screen in E. coli.
Commun Biol, 4, 2021
7A40
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BU of 7a40 by Molmil
Nucleotide-free OSM-3 kinesin motor domain
Descriptor: GLYCEROL, Osmotic avoidance abnormal protein 3, SULFATE ION
Authors:Varela, F.P, Menetrey, J, Gigant, B.
Deposit date:2020-08-19
Release date:2021-02-03
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.297 Å)
Cite:Structural snapshots of the kinesin-2 OSM-3 along its nucleotide cycle: implications for the ATP hydrolysis mechanism.
Febs Open Bio, 11, 2021

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數據於2025-10-15公開中

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