8RAS
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![BU of 8ras by Molmil](/molmil-images/mine/8ras) | Plastid-encoded RNA polymerase transcription elongation complex | Descriptor: | DNA (81-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | Authors: | Webster, M.W, Pramanick, I, Vergara-Cruces, A. | Deposit date: | 2023-12-01 | Release date: | 2024-03-06 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (2.62 Å) | Cite: | Structure of the plant plastid-encoded RNA polymerase. Cell, 187, 2024
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6VFS
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![BU of 6vfs by Molmil](/molmil-images/mine/6vfs) | ClpXP from Neisseria meningitidis - Conformation A | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit ClpX, ... | Authors: | Ripstein, Z.A, Vahidi, S, Houry, W.A, Rubinstein, J.L, Kay, L.E. | Deposit date: | 2020-01-06 | Release date: | 2020-01-22 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | A processive rotary mechanism couples substrate unfolding and proteolysis in the ClpXP degradation machinery. Elife, 9, 2020
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6UZA
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![BU of 6uza by Molmil](/molmil-images/mine/6uza) | Cryo-EM structure of human TRPC6 in complex with antagonist AM-1473 | Descriptor: | 2-[[(2~{S})-2-decanoyloxypropoxy]-oxidanyl-phosphoryl]oxyethyl-trimethyl-azanium, 4-({(1R,2R)-2-[(3R)-3-aminopiperidin-1-yl]-2,3-dihydro-1H-inden-1-yl}oxy)benzonitrile, CHOLESTEROL HEMISUCCINATE, ... | Authors: | Bai, Y, Yu, X, Huang, X, Chen, H. | Deposit date: | 2019-11-14 | Release date: | 2020-03-18 | Method: | ELECTRON MICROSCOPY (3.08 Å) | Cite: | Structural basis for pharmacological modulation of the TRPC6 channel. Elife, 9, 2020
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6V4X
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![BU of 6v4x by Molmil](/molmil-images/mine/6v4x) | Cryo-EM structure of an active human histone pre-mRNA 3'-end processing machinery at 3.2 Angstrom resolution | Descriptor: | Cleavage and polyadenylation specificity factor subunit 2, Cleavage and polyadenylation specificity factor subunit 3, Small nuclear ribonucleoprotein E, ... | Authors: | Sun, Y, Zhang, Y, Walz, T, Tong, L. | Deposit date: | 2019-12-02 | Release date: | 2020-02-19 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Structure of an active human histone pre-mRNA 3'-end processing machinery. Science, 367, 2020
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8RHJ
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![BU of 8rhj by Molmil](/molmil-images/mine/8rhj) | Yeast 20S proteasome in complex with a macrocyclic oxindole epoxyketone (compound 5) | Descriptor: | CHLORIDE ION, MAGNESIUM ION, Macrocyclic oxindole epoxyketone, ... | Authors: | Goetz, M.G, Godwin, K, Price, R, Dorn, R, Merrill-Steskal, G, Hansen, H, Klemmer, W, Produturi, G, Rocha, M, Palmer, M, Molacek, L, Strater, Z, Groll, M. | Deposit date: | 2023-12-15 | Release date: | 2024-05-01 | Method: | X-RAY DIFFRACTION (3.05 Å) | Cite: | Macrocyclic Oxindole Peptide Epoxyketones-A Comparative Study of Macrocyclic Inhibitors of the 20S Proteasome. Acs Med.Chem.Lett., 15, 2024
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8RHL
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![BU of 8rhl by Molmil](/molmil-images/mine/8rhl) | Yeast 20S proteasome in complex with a linear biarylether epoxyketone (compound 15a) | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, Linear biarylether epoxyketone, ... | Authors: | Goetz, M.G, Godwin, K, Price, R, Dorn, R, Merrill-Steskal, G, Hansen, H, Klemmer, W, Produturi, G, Rocha, M, Palmer, M, Molacek, L, Strater, Z, Groll, M. | Deposit date: | 2023-12-15 | Release date: | 2024-05-01 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Macrocyclic Oxindole Peptide Epoxyketones-A Comparative Study of Macrocyclic Inhibitors of the 20S Proteasome. Acs Med.Chem.Lett., 15, 2024
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8RHK
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![BU of 8rhk by Molmil](/molmil-images/mine/8rhk) | Yeast 20S proteasome in complex with a linear oxindole epoxyketone (compound 6) | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, Linear oxindole epoxyketone, ... | Authors: | Goetz, M.G, Godwin, K, Price, R, Dorn, R, Merrill-Steskal, G, Hansen, H, Klemmer, W, Produturi, G, Rocha, M, Palmer, M, Molacek, L, Strater, Z, Groll, M. | Deposit date: | 2023-12-15 | Release date: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Macrocyclic Oxindole Peptide Epoxyketones-A Comparative Study of Macrocyclic Inhibitors of the 20S Proteasome. Acs Med.Chem.Lett., 15, 2024
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8PID
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![BU of 8pid by Molmil](/molmil-images/mine/8pid) | backtracked E. coli transcription complex paused at ops site and bound to RfaH | Descriptor: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | Authors: | Zuber, P.K, Said, N, Hilal, T, Loll, B, Wahl, M.C, Knauer, S.H. | Deposit date: | 2023-06-21 | Release date: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Concerted transformation of a hyper-paused transcription complex and its reinforcing protein. Nat Commun, 15, 2024
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8PIM
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![BU of 8pim by Molmil](/molmil-images/mine/8pim) | fully recruited RfaH bound to E. coli transcription complex paused at ops site (not complementary scaffold) | Descriptor: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | Authors: | Zuber, P.K, Said, N, Hilal, T, Loll, B, Wahl, M.C, Knauer, S.H. | Deposit date: | 2023-06-22 | Release date: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Concerted transformation of a hyper-paused transcription complex and its reinforcing protein. Nat Commun, 15, 2024
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8QAV
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![BU of 8qav by Molmil](/molmil-images/mine/8qav) | Medicago truncatula HISN5 (IGPD) in complex with MN and IG2 | Descriptor: | (2S,3S)-2,3-dihydroxy-3-(1H-imidazol-5-yl)propyl dihydrogen phosphate, Imidazoleglycerol-phosphate dehydratase, MANGANESE (II) ION | Authors: | Witek, W, Ruszkowski, M. | Deposit date: | 2023-08-23 | Release date: | 2024-04-10 | Method: | ELECTRON MICROSCOPY (2.23 Å) | Cite: | Targeting imidazole-glycerol phosphate dehydratase in plants: novel approach for structural and functional studies, and inhibitor blueprinting. Front Plant Sci, 15, 2024
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8PH9
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![BU of 8ph9 by Molmil](/molmil-images/mine/8ph9) | E. coli RNA polymerase paused at ops site (non-complementary scaffold) | Descriptor: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | Authors: | Zuber, P.K, Said, N, Hilal, T, Loll, B, Wahl, M.C, Knauer, S.H. | Deposit date: | 2023-06-19 | Release date: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Concerted transformation of a hyper-paused transcription complex and its reinforcing protein. Nat Commun, 15, 2024
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8PHK
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![BU of 8phk by Molmil](/molmil-images/mine/8phk) | fully recruited RfaH bound to E. coli transcription complex paused at ops site | Descriptor: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | Authors: | Zuber, P.K, Said, N, Hilal, T, Loll, B, Wahl, M.C, Knauer, S.H. | Deposit date: | 2023-06-20 | Release date: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Concerted transformation of a hyper-paused transcription complex and its reinforcing protein. Nat Commun, 15, 2024
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6VE2
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![BU of 6ve2 by Molmil](/molmil-images/mine/6ve2) | Tetradecameric PilQ bound by TsaP heptamer from Pseudomonas aeruginosa | Descriptor: | Fimbrial assembly protein PilQ, LysM domain-containing protein | Authors: | McCallum, M, Tammam, S, Rubinstein, J.L, Burrows, L.L, Howell, P.L. | Deposit date: | 2019-12-28 | Release date: | 2020-12-23 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (4.3 Å) | Cite: | CryoEM map of Pseudomonas aeruginosa PilQ enables structural characterization of TsaP. Structure, 29, 2021
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6VE3
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![BU of 6ve3 by Molmil](/molmil-images/mine/6ve3) | Tetradecameric PilQ from Pseudomonas aeruginosa | Descriptor: | Fimbrial assembly protein PilQ | Authors: | McCallum, M, Tammam, S, Rubinstein, J.L, Burrows, L.L, Howell, P.L. | Deposit date: | 2019-12-28 | Release date: | 2020-12-23 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (4.3 Å) | Cite: | CryoEM map of Pseudomonas aeruginosa PilQ enables structural characterization of TsaP. Structure, 29, 2021
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6VMB
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![BU of 6vmb by Molmil](/molmil-images/mine/6vmb) | Chloroplast ATP synthase (C1, CF1FO) | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase delta chain, ... | Authors: | Yang, J.-H, Williams, D, Kandiah, E, Fromme, P, Chiu, P.-L. | Deposit date: | 2020-01-27 | Release date: | 2020-09-09 | Last modified: | 2020-09-16 | Method: | ELECTRON MICROSCOPY (5.23 Å) | Cite: | Structural basis of redox modulation on chloroplast ATP synthase. Commun Biol, 3, 2020
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6VNW
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![BU of 6vnw by Molmil](/molmil-images/mine/6vnw) | Cryo-EM structure of apo-BBSome | Descriptor: | BBS1 domain-containing protein, Bardet-Biedl syndrome 18 protein, Bardet-Biedl syndrome 2 protein homolog, ... | Authors: | Yang, S, Walz, T, Nachury, M, Chou, H. | Deposit date: | 2020-01-29 | Release date: | 2020-07-01 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.44 Å) | Cite: | Near-atomic structures of the BBSome reveal the basis for BBSome activation and binding to GPCR cargoes. Elife, 9, 2020
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6VPA
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6VOJ
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![BU of 6voj by Molmil](/molmil-images/mine/6voj) | Chloroplast ATP synthase (R3, CF1FO) | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase delta chain, ... | Authors: | Yang, J.-H, Williams, D, Kandiah, E, Fromme, P, Chiu, P.-L. | Deposit date: | 2020-01-30 | Release date: | 2020-09-09 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (4.34 Å) | Cite: | Structural basis of redox modulation on chloroplast ATP synthase. Commun Biol, 3, 2020
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8PEN
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![BU of 8pen by Molmil](/molmil-images/mine/8pen) | fully recruited RfaH bound to E. coli transcription complex paused at ops site (alternative state of RfaH) | Descriptor: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | Authors: | Zuber, P.K, Said, N, Hilal, T, Loll, B, Wahl, M.C, Knauer, S.H. | Deposit date: | 2023-06-14 | Release date: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Concerted transformation of a hyper-paused transcription complex and its reinforcing protein. Nat Commun, 15, 2024
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6VJI
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![BU of 6vji by Molmil](/molmil-images/mine/6vji) | |
6VXC
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![BU of 6vxc by Molmil](/molmil-images/mine/6vxc) | |
6VOF
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![BU of 6vof by Molmil](/molmil-images/mine/6vof) | Chloroplast ATP synthase (O2, CF1FO) | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase delta chain, ... | Authors: | Yang, J.-H, Williams, D, Kandiah, E, Fromme, P, Chiu, P.-L. | Deposit date: | 2020-01-30 | Release date: | 2020-09-09 | Last modified: | 2020-09-16 | Method: | ELECTRON MICROSCOPY (4.51 Å) | Cite: | Structural basis of redox modulation on chloroplast ATP synthase. Commun Biol, 3, 2020
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8P0K
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8P1S
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![BU of 8p1s by Molmil](/molmil-images/mine/8p1s) | Bifidobacterium asteroides alpha-L-fucosidase (TT1819) in complex with fucose. | Descriptor: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Bifidobacterium asteroides alpha-L-fucosidase (TT1819), ... | Authors: | Owen, C.D, Penner, M, Gascuena, A.N, Wu, H, Hernando, P.J, Monaco, S, Le Gall, G, Gardner, R, Ndeh, D, Urbanowicz, P.A, Spencer, D.I.R, Walsh, M.A, Angulo, J, Juge, N. | Deposit date: | 2023-05-12 | Release date: | 2024-05-22 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Exploring sequence, structure and function of microbial fucosidases from glycoside hydrolase GH29 family To Be Published
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8RIT
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![BU of 8rit by Molmil](/molmil-images/mine/8rit) | |