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8RAS
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BU of 8ras by Molmil
Plastid-encoded RNA polymerase transcription elongation complex
Descriptor: DNA (81-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:Webster, M.W, Pramanick, I, Vergara-Cruces, A.
Deposit date:2023-12-01
Release date:2024-03-06
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (2.62 Å)
Cite:Structure of the plant plastid-encoded RNA polymerase.
Cell, 187, 2024
6VFS
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BU of 6vfs by Molmil
ClpXP from Neisseria meningitidis - Conformation A
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit ClpX, ...
Authors:Ripstein, Z.A, Vahidi, S, Houry, W.A, Rubinstein, J.L, Kay, L.E.
Deposit date:2020-01-06
Release date:2020-01-22
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:A processive rotary mechanism couples substrate unfolding and proteolysis in the ClpXP degradation machinery.
Elife, 9, 2020
6UZA
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BU of 6uza by Molmil
Cryo-EM structure of human TRPC6 in complex with antagonist AM-1473
Descriptor: 2-[[(2~{S})-2-decanoyloxypropoxy]-oxidanyl-phosphoryl]oxyethyl-trimethyl-azanium, 4-({(1R,2R)-2-[(3R)-3-aminopiperidin-1-yl]-2,3-dihydro-1H-inden-1-yl}oxy)benzonitrile, CHOLESTEROL HEMISUCCINATE, ...
Authors:Bai, Y, Yu, X, Huang, X, Chen, H.
Deposit date:2019-11-14
Release date:2020-03-18
Method:ELECTRON MICROSCOPY (3.08 Å)
Cite:Structural basis for pharmacological modulation of the TRPC6 channel.
Elife, 9, 2020
6V4X
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BU of 6v4x by Molmil
Cryo-EM structure of an active human histone pre-mRNA 3'-end processing machinery at 3.2 Angstrom resolution
Descriptor: Cleavage and polyadenylation specificity factor subunit 2, Cleavage and polyadenylation specificity factor subunit 3, Small nuclear ribonucleoprotein E, ...
Authors:Sun, Y, Zhang, Y, Walz, T, Tong, L.
Deposit date:2019-12-02
Release date:2020-02-19
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structure of an active human histone pre-mRNA 3'-end processing machinery.
Science, 367, 2020
8RHJ
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BU of 8rhj by Molmil
Yeast 20S proteasome in complex with a macrocyclic oxindole epoxyketone (compound 5)
Descriptor: CHLORIDE ION, MAGNESIUM ION, Macrocyclic oxindole epoxyketone, ...
Authors:Goetz, M.G, Godwin, K, Price, R, Dorn, R, Merrill-Steskal, G, Hansen, H, Klemmer, W, Produturi, G, Rocha, M, Palmer, M, Molacek, L, Strater, Z, Groll, M.
Deposit date:2023-12-15
Release date:2024-05-01
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:Macrocyclic Oxindole Peptide Epoxyketones-A Comparative Study of Macrocyclic Inhibitors of the 20S Proteasome.
Acs Med.Chem.Lett., 15, 2024
8RHL
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BU of 8rhl by Molmil
Yeast 20S proteasome in complex with a linear biarylether epoxyketone (compound 15a)
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, Linear biarylether epoxyketone, ...
Authors:Goetz, M.G, Godwin, K, Price, R, Dorn, R, Merrill-Steskal, G, Hansen, H, Klemmer, W, Produturi, G, Rocha, M, Palmer, M, Molacek, L, Strater, Z, Groll, M.
Deposit date:2023-12-15
Release date:2024-05-01
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Macrocyclic Oxindole Peptide Epoxyketones-A Comparative Study of Macrocyclic Inhibitors of the 20S Proteasome.
Acs Med.Chem.Lett., 15, 2024
8RHK
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BU of 8rhk by Molmil
Yeast 20S proteasome in complex with a linear oxindole epoxyketone (compound 6)
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, Linear oxindole epoxyketone, ...
Authors:Goetz, M.G, Godwin, K, Price, R, Dorn, R, Merrill-Steskal, G, Hansen, H, Klemmer, W, Produturi, G, Rocha, M, Palmer, M, Molacek, L, Strater, Z, Groll, M.
Deposit date:2023-12-15
Release date:2024-05-01
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Macrocyclic Oxindole Peptide Epoxyketones-A Comparative Study of Macrocyclic Inhibitors of the 20S Proteasome.
Acs Med.Chem.Lett., 15, 2024
8PID
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BU of 8pid by Molmil
backtracked E. coli transcription complex paused at ops site and bound to RfaH
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Zuber, P.K, Said, N, Hilal, T, Loll, B, Wahl, M.C, Knauer, S.H.
Deposit date:2023-06-21
Release date:2024-04-24
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Concerted transformation of a hyper-paused transcription complex and its reinforcing protein.
Nat Commun, 15, 2024
8PIM
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BU of 8pim by Molmil
fully recruited RfaH bound to E. coli transcription complex paused at ops site (not complementary scaffold)
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Zuber, P.K, Said, N, Hilal, T, Loll, B, Wahl, M.C, Knauer, S.H.
Deposit date:2023-06-22
Release date:2024-04-24
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Concerted transformation of a hyper-paused transcription complex and its reinforcing protein.
Nat Commun, 15, 2024
8QAV
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BU of 8qav by Molmil
Medicago truncatula HISN5 (IGPD) in complex with MN and IG2
Descriptor: (2S,3S)-2,3-dihydroxy-3-(1H-imidazol-5-yl)propyl dihydrogen phosphate, Imidazoleglycerol-phosphate dehydratase, MANGANESE (II) ION
Authors:Witek, W, Ruszkowski, M.
Deposit date:2023-08-23
Release date:2024-04-10
Method:ELECTRON MICROSCOPY (2.23 Å)
Cite:Targeting imidazole-glycerol phosphate dehydratase in plants: novel approach for structural and functional studies, and inhibitor blueprinting.
Front Plant Sci, 15, 2024
8PH9
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BU of 8ph9 by Molmil
E. coli RNA polymerase paused at ops site (non-complementary scaffold)
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Zuber, P.K, Said, N, Hilal, T, Loll, B, Wahl, M.C, Knauer, S.H.
Deposit date:2023-06-19
Release date:2024-04-24
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Concerted transformation of a hyper-paused transcription complex and its reinforcing protein.
Nat Commun, 15, 2024
8PHK
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BU of 8phk by Molmil
fully recruited RfaH bound to E. coli transcription complex paused at ops site
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Zuber, P.K, Said, N, Hilal, T, Loll, B, Wahl, M.C, Knauer, S.H.
Deposit date:2023-06-20
Release date:2024-04-24
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Concerted transformation of a hyper-paused transcription complex and its reinforcing protein.
Nat Commun, 15, 2024
6VE2
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BU of 6ve2 by Molmil
Tetradecameric PilQ bound by TsaP heptamer from Pseudomonas aeruginosa
Descriptor: Fimbrial assembly protein PilQ, LysM domain-containing protein
Authors:McCallum, M, Tammam, S, Rubinstein, J.L, Burrows, L.L, Howell, P.L.
Deposit date:2019-12-28
Release date:2020-12-23
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:CryoEM map of Pseudomonas aeruginosa PilQ enables structural characterization of TsaP.
Structure, 29, 2021
6VE3
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BU of 6ve3 by Molmil
Tetradecameric PilQ from Pseudomonas aeruginosa
Descriptor: Fimbrial assembly protein PilQ
Authors:McCallum, M, Tammam, S, Rubinstein, J.L, Burrows, L.L, Howell, P.L.
Deposit date:2019-12-28
Release date:2020-12-23
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:CryoEM map of Pseudomonas aeruginosa PilQ enables structural characterization of TsaP.
Structure, 29, 2021
6VMB
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BU of 6vmb by Molmil
Chloroplast ATP synthase (C1, CF1FO)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase delta chain, ...
Authors:Yang, J.-H, Williams, D, Kandiah, E, Fromme, P, Chiu, P.-L.
Deposit date:2020-01-27
Release date:2020-09-09
Last modified:2020-09-16
Method:ELECTRON MICROSCOPY (5.23 Å)
Cite:Structural basis of redox modulation on chloroplast ATP synthase.
Commun Biol, 3, 2020
6VNW
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BU of 6vnw by Molmil
Cryo-EM structure of apo-BBSome
Descriptor: BBS1 domain-containing protein, Bardet-Biedl syndrome 18 protein, Bardet-Biedl syndrome 2 protein homolog, ...
Authors:Yang, S, Walz, T, Nachury, M, Chou, H.
Deposit date:2020-01-29
Release date:2020-07-01
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.44 Å)
Cite:Near-atomic structures of the BBSome reveal the basis for BBSome activation and binding to GPCR cargoes.
Elife, 9, 2020
6VPA
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BU of 6vpa by Molmil
Scabin (N110A) toxin from Streptomyces scabies
Descriptor: Scabin
Authors:Lyons, B, Lidster, T, Merrill, A.R.
Deposit date:2020-02-02
Release date:2021-01-13
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Mapping the DNA-Binding Motif of Scabin Toxin, a Guanine Modifying Enzyme from Streptomyces scabies .
Toxins, 13, 2021
6VOJ
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BU of 6voj by Molmil
Chloroplast ATP synthase (R3, CF1FO)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase delta chain, ...
Authors:Yang, J.-H, Williams, D, Kandiah, E, Fromme, P, Chiu, P.-L.
Deposit date:2020-01-30
Release date:2020-09-09
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (4.34 Å)
Cite:Structural basis of redox modulation on chloroplast ATP synthase.
Commun Biol, 3, 2020
8PEN
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BU of 8pen by Molmil
fully recruited RfaH bound to E. coli transcription complex paused at ops site (alternative state of RfaH)
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Zuber, P.K, Said, N, Hilal, T, Loll, B, Wahl, M.C, Knauer, S.H.
Deposit date:2023-06-14
Release date:2024-04-24
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Concerted transformation of a hyper-paused transcription complex and its reinforcing protein.
Nat Commun, 15, 2024
6VJI
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BU of 6vji by Molmil
Structure of mammalian NEIL2 from Monodelphis domestica
Descriptor: Nei like DNA glycosylase 2, ZINC ION
Authors:Eckenroth, B.E, Doublie, S.
Deposit date:2020-01-16
Release date:2020-08-12
Last modified:2021-01-20
Method:X-RAY DIFFRACTION (2.54 Å)
Cite:Unique Structural Features of Mammalian NEIL2 DNA Glycosylase Prime Its Activity for Diverse DNA Substrates and Environments.
Structure, 29, 2021
6VXC
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BU of 6vxc by Molmil
Crystal structure of hydroxyproline dehydratase (HypD) from Clostridioides difficile
Descriptor: GLYCEROL, Trans-4-hydroxy-L-proline dehydratase
Authors:Backman, L.R.F, Drennan, C.L.
Deposit date:2020-02-21
Release date:2020-04-08
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Molecular basis for catabolism of the abundant metabolitetrans-4-hydroxy-L-proline by a microbial glycyl radical enzyme.
Elife, 9, 2020
6VOF
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BU of 6vof by Molmil
Chloroplast ATP synthase (O2, CF1FO)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase delta chain, ...
Authors:Yang, J.-H, Williams, D, Kandiah, E, Fromme, P, Chiu, P.-L.
Deposit date:2020-01-30
Release date:2020-09-09
Last modified:2020-09-16
Method:ELECTRON MICROSCOPY (4.51 Å)
Cite:Structural basis of redox modulation on chloroplast ATP synthase.
Commun Biol, 3, 2020
8P0K
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BU of 8p0k by Molmil
Cryo EM map and model of the vaccinia RNA polymerase intermediate pre-initiation open promoter complex, module 2 of capping enzyme mobile
Descriptor: DNA-directed RNA polymerase 133 kDa polypeptide, DNA-directed RNA polymerase 147 kDa polypeptide, DNA-directed RNA polymerase 18 kDa subunit, ...
Authors:Grimm, C, Jungwirth, S, Fischer, U.
Deposit date:2023-05-10
Release date:2024-05-22
Method:ELECTRON MICROSCOPY (2.64 Å)
Cite:Cryo EM map and model of the vaccinia RNA polymerase intermediate pre-initiation open promoter complex (CASP target)
To Be Published
8P1S
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BU of 8p1s by Molmil
Bifidobacterium asteroides alpha-L-fucosidase (TT1819) in complex with fucose.
Descriptor: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Bifidobacterium asteroides alpha-L-fucosidase (TT1819), ...
Authors:Owen, C.D, Penner, M, Gascuena, A.N, Wu, H, Hernando, P.J, Monaco, S, Le Gall, G, Gardner, R, Ndeh, D, Urbanowicz, P.A, Spencer, D.I.R, Walsh, M.A, Angulo, J, Juge, N.
Deposit date:2023-05-12
Release date:2024-05-22
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Exploring sequence, structure and function of microbial fucosidases from glycoside hydrolase GH29 family
To Be Published
8RIT
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BU of 8rit by Molmil
Dimeric mutant S103D of the BTB domain of ZBTB8A from Xenopus laevis
Descriptor: Zinc finger and BTB domain-containing protein 8A.1-A
Authors:Coste, F, Suskiewicz, M.J.
Deposit date:2023-12-19
Release date:2024-06-05
Method:X-RAY DIFFRACTION (3.75 Å)
Cite:Dimeric mutant S103D of the BTB domain of ZBTB8A from Xenopus laevis
To Be Published

223790

數據於2024-08-14公開中

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