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8G0D	Cryo-EM structure of TBAJ-876-bound Mycobacterium smegmatis ATP synthase rotational state 2 (backbone model) Descriptor: (1R,2S)-1-(6-bromo-2-methoxyquinolin-3-yl)-2-(2,6-dimethoxypyridin-4-yl)-4-(dimethylamino)-1-(2,3,6-trimethoxypyridin-4-yl)butan-2-ol, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase epsilon chain, ... Authors: Courbon, G.M, Rubinstein, J.L. Deposit date: 2023-01-31 Release date: 2023-02-15 Last modified: 2024-06-19 Method: ELECTRON MICROSCOPY (2.9 Å) Cite: Mechanism of mycobacterial ATP synthase inhibition by squaramides and second generation diarylquinolines. Embo J., 42, 2023
8G09	Cryo-EM structure of SQ31f-bound Mycobacterium smegmatis ATP synthase rotational state 2 (backbone model) Descriptor: 3-[4-(morpholin-4-yl)phenyl]-4-{[(pyridin-2-yl)methyl]amino}cyclobut-3-ene-1,2-dione, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase epsilon chain, ... Authors: Courbon, G.M, Rubinstein, J.L. Deposit date: 2023-01-31 Release date: 2023-02-15 Last modified: 2024-06-19 Method: ELECTRON MICROSCOPY (3.1 Å) Cite: Mechanism of mycobacterial ATP synthase inhibition by squaramides and second generation diarylquinolines. Embo J., 42, 2023
8G0C	Cryo-EM structure of TBAJ-876-bound Mycobacterium smegmatis ATP synthase rotational state 1 (backbone model) Descriptor: (1R,2S)-1-(6-bromo-2-methoxyquinolin-3-yl)-2-(2,6-dimethoxypyridin-4-yl)-4-(dimethylamino)-1-(2,3,6-trimethoxypyridin-4-yl)butan-2-ol, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase epsilon chain, ... Authors: Courbon, G.M, Rubinstein, J.L. Deposit date: 2023-01-31 Release date: 2023-02-15 Last modified: 2024-06-19 Method: ELECTRON MICROSCOPY (2.8 Å) Cite: Mechanism of mycobacterial ATP synthase inhibition by squaramides and second generation diarylquinolines. Embo J., 42, 2023
8G0A	Cryo-EM structure of SQ31f-bound Mycobacterium smegmatis ATP synthase rotational state 3 Descriptor: 3-[4-(morpholin-4-yl)phenyl]-4-{[(pyridin-2-yl)methyl]amino}cyclobut-3-ene-1,2-dione, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase epsilon chain, ... Authors: Courbon, G.M, Rubinstein, J.L. Deposit date: 2023-01-31 Release date: 2023-02-15 Last modified: 2024-06-19 Method: ELECTRON MICROSCOPY (2.9 Å) Cite: Mechanism of mycobacterial ATP synthase inhibition by squaramides and second generation diarylquinolines. Embo J., 42, 2023
1L6T	STRUCTURE OF ALA24/ASP61 TO ASP24/ASN61 SUBSTITUTED SUBUNIT C OF ESCHERICHIA COLI ATP SYNTHASE Descriptor: ATP SYNTHASE C CHAIN Authors: Dmitriev, O.Y, Abildgaard, F, Markley, J.L, Fillingame, R.H. Deposit date: 2002-03-13 Release date: 2002-07-24 Last modified: 2024-05-22 Method: SOLUTION NMR Cite: Structure of Ala24/Asp61 --> Asp24/Asn61 substituted subunit c of Escherichia coli ATP synthase: implications for the mechanism of proton transport and rotary movement in the F0 complex. Biochemistry, 41, 2002
6CP5	Monomer yeast ATP synthase Fo reconstituted in nanodisc with inhibitor of oligomycin bound generated from focused refinement. Descriptor: ATP synthase protein 8, ATP synthase subunit 4, mitochondrial, ... Authors: Srivastava, A.P, Luo, M, Symersky, J, Liao, M.F, Mueller, D.M. Deposit date: 2018-03-13 Release date: 2018-04-11 Last modified: 2024-10-23 Method: ELECTRON MICROSCOPY (4.2 Å) Cite: High-resolution cryo-EM analysis of the yeast ATP synthase in a lipid membrane. Science, 360, 2018
2KHK	NMR solution structure of the b30-82 domain of subunit b of Escherichia coli F1FO ATP synthase Descriptor: ATP synthase subunit b Authors: Priya, R, Biukovic, G, Gayen, S, Vivekanandan, S, Gruber, G. Deposit date: 2009-04-08 Release date: 2009-12-15 Last modified: 2024-05-15 Method: SOLUTION NMR Cite: Solution structure, determined by nuclear magnetic resonance, of the b30-82 domain of subunit b of Escherichia coli F1Fo ATP synthase J.Bacteriol., 191, 2009
6CP7	Monomer yeast ATP synthase Fo reconstituted in nanodisc generated from masked refinement. Descriptor: ATP synthase protein 8, ATP synthase subunit 4, mitochondrial, ... Authors: Srivastava, A.P, Luo, M, Symersky, J, Liao, M.F, Mueller, D.M. Deposit date: 2018-03-13 Release date: 2018-04-11 Last modified: 2024-10-23 Method: ELECTRON MICROSCOPY (4.1 Å) Cite: High-resolution cryo-EM analysis of the yeast ATP synthase in a lipid membrane. Science, 360, 2018
7Y5C	Cryo-EM structure of F-ATP synthase from Mycolicibacterium smegmatis (rotational state 2) Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase epsilon chain, ... Authors: Saw, W.-G, Wong, C.F, Grueber, G. Deposit date: 2022-06-16 Release date: 2022-11-23 Last modified: 2024-07-03 Method: ELECTRON MICROSCOPY (4.7 Å) Cite: Structural Elements Involved in ATP Hydrolysis Inhibition and ATP Synthesis of Tuberculosis and Nontuberculous Mycobacterial F-ATP Synthase Decipher New Targets for Inhibitors. Antimicrob.Agents Chemother., 66, 2022
7Y5B	Cryo-EM structure of F-ATP synthase from Mycolicibacterium smegmatis (rotational state 1) Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase epsilon chain, ... Authors: Saw, W.-G, Wong, C.F, Grueber, G. Deposit date: 2022-06-16 Release date: 2022-11-23 Last modified: 2024-07-03 Method: ELECTRON MICROSCOPY (4.4 Å) Cite: Structural Elements Involved in ATP Hydrolysis Inhibition and ATP Synthesis of Tuberculosis and Nontuberculous Mycobacterial F-ATP Synthase Decipher New Targets for Inhibitors. Antimicrob.Agents Chemother., 66, 2022
1VZS	Solution structure of subunit F6 from the peripheral stalk region of ATP synthase from bovine heart mitochondria Descriptor: ATP SYNTHASE COUPLING FACTOR 6, MITOCHONDRIAL PRECURSOR Authors: Carbajo, R.J, Silvester, J.A, Runswick, M.J, Walker, J.E, Neuhaus, D. Deposit date: 2004-05-25 Release date: 2004-09-02 Last modified: 2024-05-15 Method: SOLUTION NMR Cite: Solution Structure of Subunit F(6) from the Peripheral Stalk Region of ATP Synthase from Bovine Heart Mitochondria J.Mol.Biol., 342, 2004
6ZIT	bovine ATP synthase Stator domain, state 2 Descriptor: ATP synthase F(0) complex subunit B1, mitochondrial, ATP synthase F(0) complex subunit C2, ... Authors: Spikes, T.E, Montgomery, M.G, Walker, J.E. Deposit date: 2020-06-26 Release date: 2020-09-09 Last modified: 2025-04-09 Method: ELECTRON MICROSCOPY (3.49 Å) Cite: Structure of the dimeric ATP synthase from bovine mitochondria. Proc.Natl.Acad.Sci.USA, 117, 2020
6ZIQ	bovine ATP synthase stator domain, state 1 Descriptor: ATP synthase F(0) complex subunit B1, mitochondrial, ATP synthase F(0) complex subunit C1, ... Authors: Spikes, T.E, Montgomery, M.G, Walker, J.E. Deposit date: 2020-06-26 Release date: 2020-09-09 Last modified: 2025-04-09 Method: ELECTRON MICROSCOPY (4.33 Å) Cite: Structure of the dimeric ATP synthase from bovine mitochondria. Proc.Natl.Acad.Sci.USA, 117, 2020
8KHF	Structure of the human ATP synthase bound to bedaquiline (membrane domain) Descriptor: ATP synthase F(0) complex subunit B1, mitochondrial, ATP synthase F(0) complex subunit C1, ... Authors: Lai, Y, Zhang, Y. Deposit date: 2023-08-21 Release date: 2024-05-01 Last modified: 2024-08-21 Method: ELECTRON MICROSCOPY (3.13 Å) Cite: Inhibition of M. tuberculosis and human ATP synthase by BDQ and TBAJ-587. Nature, 631, 2024
6ZG7	bovine ATP synthase rotor domain, state 1 Descriptor: ATP synthase F(0) complex subunit C2, mitochondrial, ATP synthase subunit delta, ... Authors: Spikes, T, Montgomery, M.G, Walker, J.E. Deposit date: 2020-06-18 Release date: 2020-09-09 Last modified: 2025-04-09 Method: ELECTRON MICROSCOPY (3.49 Å) Cite: Structure of the dimeric ATP synthase from bovine mitochondria. Proc.Natl.Acad.Sci.USA, 117, 2020
9BPG	Artemia franciscana ATP synthase FO domain, state 1, pH 7.0 Descriptor: ATP synthase protein 8, ATP synthase subunit 6.8PL, ATP synthase subunit a, ... Authors: Mnatsakanyan, N, Mello, J.F.R. Deposit date: 2024-05-07 Release date: 2025-03-26 Method: ELECTRON MICROSCOPY (3.3 Å) Cite: Cryo-EM structure of the brine shrimp mitochondrial ATP synthase suggests an inactivation mechanism for the ATP synthase leak channel. Cell Death Differ., 2025
6TQJ	Crystal structure of the c14 ring of the F1FO ATP synthase from spinach chloroplast Descriptor: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, ATP synthase subunit c, chloroplastic, ... Authors: Kovalev, K, Gushchin, I, Vlasov, A, Round, E, Polovinkin, V, Gordeliy, V. Deposit date: 2019-12-16 Release date: 2019-12-25 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Unusual features of the c-ring of F1FOATP synthases. Sci Rep, 9, 2019
1C99	ASP61 DEPROTONATED FORM OF SUBUNIT C OF THE F1FO ATP SYNTHASE OF ESCHERICHIA COLI Descriptor: PROTEOLIPID F1FO OF ATP SYNTHASE Authors: Rastogi, V.K, Girvin, M.E. Deposit date: 1999-04-30 Release date: 1999-11-19 Last modified: 2023-12-27 Method: SOLUTION NMR Cite: Structural changes linked to proton translocation by subunit c of the ATP synthase. Nature, 402, 1999
7NL9	Mycobacterium smegmatis ATP synthase Fo state 3 Descriptor: ATP synthase epsilon chain, ATP synthase gamma chain, ATP synthase subunit a, ... Authors: Montgomery, M.G, Petri, J, Spikes, T.E, Walker, J.E. Deposit date: 2021-02-22 Release date: 2021-10-27 Last modified: 2024-07-10 Method: ELECTRON MICROSCOPY (2.86 Å) Cite: Structure of the ATP synthase from Mycobacterium smegmatis provides targets for treating tuberculosis. Proc.Natl.Acad.Sci.USA, 118, 2021
7NKP	Mycobacterium smegmatis ATP synthase Fo state 2 Descriptor: ATP synthase epsilon chain, ATP synthase gamma chain, ATP synthase subunit a, ... Authors: Montgomery, M.G, Petri, J, Spikes, T.E, Walker, J.E. Deposit date: 2021-02-18 Release date: 2021-10-27 Last modified: 2024-07-10 Method: ELECTRON MICROSCOPY (4.06 Å) Cite: Structure of the ATP synthase from Mycobacterium smegmatis provides targets for treating tuberculosis. Proc.Natl.Acad.Sci.USA, 118, 2021
7NK9	Mycobacterium smegmatis ATP synthase Fo domain state 1 Descriptor: ATP synthase epsilon chain, ATP synthase gamma chain, ATP synthase subunit a, ... Authors: Montgomery, M.G, Petri, J, Spikes, T.E, Walker, J.E. Deposit date: 2021-02-17 Release date: 2021-11-03 Last modified: 2024-07-10 Method: ELECTRON MICROSCOPY (2.9 Å) Cite: Structure of the ATP synthase from Mycobacterium smegmatis provides targets for treating tuberculosis. Proc.Natl.Acad.Sci.USA, 118, 2021
1ATY	DETERMINATION OF LOCAL PROTEIN STRUCTURE BY SPIN LABEL DIFFERENCE 2D NMR: THE REGION NEIGHBORING ASP61 OF SUBUNIT C OF THE F1FO ATP SYNTHASE Descriptor: F1F0 ATP SYNTHASE (SUBUNIT C) Authors: Girvin, M.E, Fillingame, R.H. Deposit date: 1994-10-05 Release date: 1994-12-20 Last modified: 2024-05-22 Method: SOLUTION NMR Cite: Determination of local protein structure by spin label difference 2D NMR: the region neighboring Asp61 of subunit c of the F1F0 ATP synthase. Biochemistry, 34, 1995
5FIL	Bovine mitochondrial ATP synthase state 3b Descriptor: ATP SYNTHASE F(0) COMPLEX SUBUNIT B1, MITOCHONDRIAL, ATP SYNTHASE F(0) COMPLEX SUBUNIT C1, ... Authors: Zhou, A, Rohou, A, Schep, D.G, Bason, J.V, Montgomery, M.G, Walker, J.E, Grigorieff, N, Rubinstein, J.L. Deposit date: 2015-09-28 Release date: 2015-10-14 Last modified: 2024-05-08 Method: ELECTRON MICROSCOPY (7.1 Å) Cite: Structure and conformational states of the bovine mitochondrial ATP synthase by cryo-EM. Elife, 4, 2015
6ZIU	bovine ATP synthase stator domain, state 3 Descriptor: ATP synthase F(0) complex subunit B1, mitochondrial, ATP synthase protein 8, ... Authors: Spikes, T.E, Montgomery, M.G, Walker, J.E. Deposit date: 2020-06-26 Release date: 2020-09-09 Last modified: 2024-05-01 Method: ELECTRON MICROSCOPY (6.02 Å) Cite: Structure of the dimeric ATP synthase from bovine mitochondria. Proc.Natl.Acad.Sci.USA, 117, 2020
5FIK	Bovine mitochondrial ATP synthase state 3a Descriptor: ATP SYNTHASE F(0) COMPLEX SUBUNIT B1, MITOCHONDRIAL, ATP SYNTHASE F(0) COMPLEX SUBUNIT C1, ... Authors: Zhou, A, Rohou, A, Schep, D.G, Bason, J.V, Montgomery, M.G, Walker, J.E, Grigorieff, N, Rubinstein, J.L. Deposit date: 2015-09-28 Release date: 2015-10-14 Last modified: 2024-05-08 Method: ELECTRON MICROSCOPY (6.4 Å) Cite: Structure and conformational states of the bovine mitochondrial ATP synthase by cryo-EM. Elife, 4, 2015

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