8G0C
Cryo-EM structure of TBAJ-876-bound Mycobacterium smegmatis ATP synthase rotational state 1 (backbone model)
Summary for 8G0C
| Entry DOI | 10.2210/pdb8g0c/pdb |
| EMDB information | 29648 29649 29650 29651 29652 29653 29654 29655 |
| Descriptor | ATP synthase subunit alpha, MAGNESIUM ION, PHOSPHATE ION, ... (12 entities in total) |
| Functional Keywords | atp synthase, mycobacterial, inhibitor, tuberculosis, antibiotic, hydrolase, translocase-inhibitor complex, translocase/inhibitor |
| Biological source | Mycolicibacterium smegmatis MC2 155 More |
| Total number of polymer chains | 20 |
| Total formula weight | 555498.84 |
| Authors | Courbon, G.M.,Rubinstein, J.L. (deposition date: 2023-01-31, release date: 2023-02-15, Last modification date: 2023-08-09) |
| Primary citation | Courbon, G.M.,Palme, P.R.,Mann, L.,Richter, A.,Imming, P.,Rubinstein, J.L. Mechanism of mycobacterial ATP synthase inhibition by squaramides and second generation diarylquinolines. Embo J., 42:e113687-e113687, 2023 Cited by PubMed: 37377118DOI: 10.15252/embj.2023113687 PDB entries with the same primary citation |
| Experimental method | ELECTRON MICROSCOPY (2.8 Å) |
Structure validation
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