5GAO
| Head region of the yeast spliceosomal U4/U6.U5 tri-snRNP | Descriptor: | Pre-mRNA-splicing factor 8, Pre-mRNA-splicing helicase BRR2, Saccharomyces cerevisiae strain UOA_M2 chromosome 5 sequence, ... | Authors: | Nguyen, T.H.D, Galej, W.P, Bai, X.C, Oubridge, C, Scheres, S.H.W, Newman, A.J, Nagai, K. | Deposit date: | 2015-12-15 | Release date: | 2016-01-27 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (4.2 Å) | Cite: | Cryo-EM structure of the yeast U4/U6.U5 tri-snRNP at 3.7 angstrom resolution. Nature, 530, 2016
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7BZV
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5O36
| Japanese encephalitis virus non-structural protein 1' C-terminal domain | Descriptor: | Japanese encephalitis virus non-structural protein 1' (NS1'),Japanese encephalitis virus non-structural protein 1' (NS1'), N-PROPANOL, SULFATE ION | Authors: | Thanalai, P, Wright, G.S.A, Antonyuk, S.V. | Deposit date: | 2017-05-23 | Release date: | 2018-01-24 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structural Study of the C-Terminal Domain of Nonstructural Protein 1 from Japanese Encephalitis Virus. J. Virol., 92, 2018
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3E46
| Crystal structure of ubiquitin-conjugating enzyme E2-25kDa (Huntington interacting protein 2) M172A mutant | Descriptor: | CALCIUM ION, Ubiquitin-conjugating enzyme E2-25 kDa | Authors: | Hughes, R.C, Wilson, R.C, Flatt, J.W, Meehan, E.J, Ng, J.D, Twigg, P.D. | Deposit date: | 2008-08-09 | Release date: | 2008-08-26 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.86 Å) | Cite: | Structure of full-length ubiquitin-conjugating enzyme E2-25K (huntingtin-interacting protein 2). Acta Crystallogr.,Sect.F, 65, 2009
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5HNH
| Crystal structure of pyrene- and phenanthrene-modified DNA in complex with the BpuJ1 endonuclease binding domain | Descriptor: | DNA (5'-D(*GP*(YPY)P*AP*CP*CP*CP*GP*TP*GP*GP*A)-3'), DNA (5'-D(*TP*CP*CP*AP*CP*GP*GP*GP*T*(YPY)*(YPY)*C)-3'), Restriction endonuclease R.BpuJI | Authors: | Probst, M, Aeschimann, W, Chau, T.-T.-H, Langenegger, S.M, Stocker, A, Haener, R. | Deposit date: | 2016-01-18 | Release date: | 2016-08-17 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.876 Å) | Cite: | Structural insight into DNA-assembled oligochromophores: crystallographic analysis of pyrene- and phenanthrene-modified DNA in complex with BpuJI endonuclease. Nucleic Acids Res., 44, 2016
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6U3Y
| Structure-based discovery of a novel small-molecule inhibitor of methicillin-resistant S. aureus | Descriptor: | ACETATE ION, Gamma-hemolysin subunit A, Panton-Valentine Leucocidin F, ... | Authors: | Liu, J, Kozhaya, L, Torres, V.J, Unutmaz, D, Lu, M. | Deposit date: | 2019-08-22 | Release date: | 2020-03-25 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.04 Å) | Cite: | Structure-based discovery of a small-molecule inhibitor of methicillin-resistantStaphylococcus aureusvirulence. J.Biol.Chem., 295, 2020
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6U4V
| Non-crosslinked wild type cysteine dioxygenase | Descriptor: | Cysteine dioxygenase type 1, FE (III) ION | Authors: | Meneely, K.M, Chilton, A.S, Forbes, D.L, Ellis, H.R, Lamb, A.L. | Deposit date: | 2019-08-26 | Release date: | 2020-07-08 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | The 3-His Metal Coordination Site Promotes the Coupling of Oxygen Activation to Cysteine Oxidation in Cysteine Dioxygenase. Biochemistry, 59, 2020
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6U7F
| HCoV-229E RBD Class IV in complex with human APN | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Aminopeptidase N, ... | Authors: | Tomlinson, A.C.A, Li, Z, Rini, J.M. | Deposit date: | 2019-09-02 | Release date: | 2019-11-13 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | The human coronavirus HCoV-229E S-protein structure and receptor binding. Elife, 8, 2019
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3U0M
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7W5N
| The crystal structure of the reduced form of Gluconobacter oxydans WSH-004 SNDH | Descriptor: | L-sorbosone dehydrogenase, NAD(P) dependent, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | Authors: | Li, D, Hou, X.D, Rao, Y.J, Yin, D.J, Zhou, J.W, Chen, J. | Deposit date: | 2021-11-30 | Release date: | 2023-03-01 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.988 Å) | Cite: | Structural Insight into the Catalytic Mechanisms of an L-Sorbosone Dehydrogenase. Adv Sci, 10, 2023
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7W5K
| The C296A mutant of L-sorbosone dehydrogenase (SNDH) from Gluconobacter Oxydans WSH-004 | Descriptor: | L-sorbosone dehydrogenase, NAD(P) dependent, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | Authors: | Li, D, Hou, X.D, Rao, Y.J, Zhou, J.W, Chen, J. | Deposit date: | 2021-11-30 | Release date: | 2023-03-01 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.22 Å) | Cite: | Structural Insight into the Catalytic Mechanisms of an L-Sorbosone Dehydrogenase. Adv Sci, 10, 2023
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2VY7
| The 627-domain from influenza A virus polymerase PB2 subunit | Descriptor: | POLYMERASE BASIC PROTEIN 2 | Authors: | Tarendeau, F, Crepin, T, Guilligay, D, Ruigrok, R, Cusack, S, Hart, D. | Deposit date: | 2008-07-18 | Release date: | 2008-09-09 | Last modified: | 2012-06-06 | Method: | X-RAY DIFFRACTION (1.53 Å) | Cite: | Host Determinant Residue Lysine 627 Lies on the Surface of a Discrete, Folded Domain of Influenza Virus Polymerase Pb2 Subunit Plos Pathog., 4, 2008
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4ZDC
| Yeast enoyl-CoA isomerase complexed with octanoyl-CoA | Descriptor: | 3,2-trans-enoyl-CoA isomerase, GLYCEROL, OCTANOYL-COENZYME A, ... | Authors: | Onwukwe, G.U, Koski, M.K, Wierenga, R.K. | Deposit date: | 2015-04-17 | Release date: | 2015-11-11 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.13 Å) | Cite: | Structures of yeast peroxisomal Delta (3), Delta (2)-enoyl-CoA isomerase complexed with acyl-CoA substrate analogues: the importance of hydrogen-bond networks for the reactivity of the catalytic base and the oxyanion hole. Acta Crystallogr.,Sect.D, 71, 2015
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2XY4
| X-RAY STRUCTURE OF ZNUA-WT FROM SALMONELLA ENTERICA | Descriptor: | SULFATE ION, TRIETHYLENE GLYCOL, ZINC ABC TRANSPORTER, ... | Authors: | Alaleona, F, Ilari, A, Battistoni, A, Petrarca, P, Chiancone, E. | Deposit date: | 2010-11-15 | Release date: | 2011-04-27 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.71 Å) | Cite: | The X-Ray Structure of the Zinc Transporter Znua from Salmonella Enterica Discloses a Unique Triad of Zinc Coordinating Histidines. J.Mol.Biol., 409, 2011
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7WLS
| Crystal structure of the multidrug efflux transporter BpeB from Burkholderia pseudomallei | Descriptor: | Efflux pump membrane transporter, TETRAETHYLENE GLYCOL, UNDECYL-MALTOSIDE | Authors: | Kato, T, Hung, L.-W, Yamashita, E, Okada, U, Terwilliger, T.C, Murakami, S. | Deposit date: | 2022-01-13 | Release date: | 2023-07-19 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.94 Å) | Cite: | Crystal structures of multidrug efflux transporters from Burkholderia pseudomallei suggest details of transport mechanism. Proc.Natl.Acad.Sci.USA, 120, 2023
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5HLT
| Crystal structure of pyrene- and phenanthrene-modified DNA in complex with the BpuJ1 endonuclease binding domain | Descriptor: | DNA (5'-D(*GP*YPY*TP*AP*CP*CP*CP*GP*TP*GP*GP*A)-3'), DNA (5'-D(*TP*CP*CP*AP*CP*GP*GP*GP*TP*AP*YPY*C)-3'), Restriction endonuclease R.BpuJI | Authors: | Probst, M, Aeschimann, W, Chau, T.-T.-H, Langenegger, S.M, Stocker, A, Haener, R. | Deposit date: | 2016-01-15 | Release date: | 2016-08-17 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.672 Å) | Cite: | Structural insight into DNA-assembled oligochromophores: crystallographic analysis of pyrene- and phenanthrene-modified DNA in complex with BpuJI endonuclease. Nucleic Acids Res., 44, 2016
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5HM7
| The Intracellular domain of Butyrophilin 3A1 protein | Descriptor: | BETA-MERCAPTOETHANOL, Butyrophilin subfamily 3 member A1, GLYCEROL, ... | Authors: | Adams, E.J, Gu, S. | Deposit date: | 2016-01-15 | Release date: | 2017-07-26 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.93 Å) | Cite: | Phosphoantigen-induced conformational change of butyrophilin 3A1 (BTN3A1) and its implication on V gamma 9V delta 2 T cell activation. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5WQF
| Structure of fungal meroterpenoid isomerase Trt14 | Descriptor: | CALCIUM ION, Isomerase trt14, N-PROPANOL | Authors: | Mori, T, Iwabuchi, T, Matsuda, Y, Abe, I. | Deposit date: | 2016-11-26 | Release date: | 2017-07-26 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.001 Å) | Cite: | Molecular basis for the unusual ring reconstruction in fungal meroterpenoid biogenesis Nat. Chem. Biol., 13, 2017
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7WLV
| Crystal Structure of the Multidrug effulx transporter BpeF from Burkholderia pseudomallei. | Descriptor: | DODECYL-BETA-D-MALTOSIDE, Efflux pump membrane transporter | Authors: | Kato, T, Hung, L.-W, Yamashita, E, Okada, U, Terwilliger, T.C, Murakami, S. | Deposit date: | 2022-01-13 | Release date: | 2023-07-19 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Crystal structures of multidrug efflux transporters from Burkholderia pseudomallei suggest details of transport mechanism. Proc.Natl.Acad.Sci.USA, 120, 2023
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5HN1
| Crystal structure of Interleukin-37 | Descriptor: | Interleukin-37, SULFATE ION | Authors: | Ellisdon, A.M, Nold-Petry, C.A, Nold, M.F, Whisstock, J.C. | Deposit date: | 2016-01-17 | Release date: | 2017-02-22 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Homodimerization attenuates the anti-inflammatory activity of interleukin-37. Sci Immunol, 2, 2017
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4Z8M
| Crystal structure of the MAVS-TRAF6 complex | Descriptor: | Peptide from Mitochondrial antiviral-signaling protein, TNF receptor-associated factor 6 | Authors: | Shi, Z.B, Zhou, Z. | Deposit date: | 2015-04-09 | Release date: | 2015-09-23 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.95 Å) | Cite: | Structural Insights into Mitochondrial Antiviral Signaling Protein (MAVS)-Tumor Necrosis Factor Receptor-associated Factor 6 (TRAF6) Signaling J.Biol.Chem., 290, 2015
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2XXU
| Crystal structure of the GluK2 (GluR6) M770K LBD dimer in complex with glutamate | Descriptor: | CHLORIDE ION, GLUTAMATE RECEPTOR, IONOTROPIC KAINATE 2, ... | Authors: | Nayeem, N, Mayans, O, Green, T. | Deposit date: | 2010-11-12 | Release date: | 2011-02-09 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Conformational Flexibility of the Ligand-Binding Domain Dimer in Kainate Receptor Gating and Desensitization J.Neurosci., 31, 2011
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5WQG
| Structure of fungal meroterpenoid isomerase Trt14 complexed with terretonin D | Descriptor: | CALCIUM ION, Isomerase trt14, methyl (2S,4aR,4bS,5S,6aS,10aS,10bS,12aS)-2,4b,7,7,10a,12a-hexamethyl-12-methylidene-5-oxidanyl-1,4,6,8-tetrakis(oxidanylidene) -5,6a,9,10,10b,11-hexahydro-4aH-naphtho[1,2-h]isochromene-2-carboxylate | Authors: | Mori, T, Matsuda, Y, Abe, I. | Deposit date: | 2016-11-26 | Release date: | 2017-07-26 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Molecular basis for the unusual ring reconstruction in fungal meroterpenoid biogenesis Nat. Chem. Biol., 13, 2017
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6U49
| Structure-based discovery of a novel small-molecule inhibitor of methicillin-resistant S. aureus | Descriptor: | Alpha-hemolysin, SULFATE ION, fos-choline-14 | Authors: | Liu, J, Kozhaya, L, Torres, V.J, Unutmaz, D, Lu, M. | Deposit date: | 2019-08-23 | Release date: | 2020-03-25 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Structure-based discovery of a small-molecule inhibitor of methicillin-resistantStaphylococcus aureusvirulence. J.Biol.Chem., 295, 2020
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4ZHZ
| Endonuclease inhibitor bound to influenza strain H1N1 polymerase acidic subunit N-terminal region with expelling one of the metal ions in the active site | Descriptor: | 5-(2-chlorobenzyl)-2-hydroxy-3-nitrobenzaldehyde, MANGANESE (II) ION, Polymerase acidic protein, ... | Authors: | Fudo, S, Yamamoto, N, Nukaga, M, Odagiri, T, Tashiro, M, Neya, S, Hoshino, T. | Deposit date: | 2015-04-27 | Release date: | 2015-05-13 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Two Distinctive Binding Modes of Endonuclease Inhibitors to the N-Terminal Region of Influenza Virus Polymerase Acidic Subunit Biochemistry, 55, 2016
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