5WQG

Structure of fungal meroterpenoid isomerase Trt14 complexed with terretonin D

Summary for 5WQG

Entry DOI	10.2210/pdb5wqg/pdb
Related	5WQF 5WQH 5WQI
Descriptor	Isomerase trt14, CALCIUM ION, methyl (2S,4aR,4bS,5S,6aS,10aS,10bS,12aS)-2,4b,7,7,10a,12a-hexamethyl-12-methylidene-5-oxidanyl-1,4,6,8-tetrakis(oxidanylidene) -5,6a,9,10,10b,11-hexahydro-4aH-naphtho[1,2-h]isochromene-2-carboxylate, ... (4 entities in total)
Functional Keywords	isomerase, meroterpenoid, terretonin
Biological source	Aspergillus terreus NIH 2624
Total number of polymer chains	6
Total formula weight	111605.49
Authors	Mori, T.,Matsuda, Y.,Abe, I. (deposition date: 2016-11-26, release date: 2017-07-26, Last modification date: 2023-11-08)
Primary citation	Mori, T.,Iwabuchi, T.,Hoshino, S.,Wang, H.,Matsuda, Y.,Abe, I. Molecular basis for the unusual ring reconstruction in fungal meroterpenoid biogenesis Nat. Chem. Biol., 13:1066-1073, 2017 Cited by PubMed: 28759016 DOI: 10.1038/nchembio.2443 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation