4RE9
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![BU of 4re9 by Molmil](/molmil-images/mine/4re9) | Crystal structure of human insulin degrading enzyme (IDE) in complex with compound 71290 | Descriptor: | 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 4-fluoro-N-({1-[(2R)-4-(hydroxyamino)-1-(naphthalen-2-yl)-4-oxobutan-2-yl]-1H-1,2,3-triazol-5-yl}methyl)benzamide, ... | Authors: | Liang, W.G, Deprez, R, Deprez, B, Tang, W.J. | Deposit date: | 2014-09-22 | Release date: | 2015-09-30 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.908 Å) | Cite: | Catalytic site inhibition of insulin-degrading enzyme by a small molecule induces glucose intolerance in mice. Nat Commun, 6, 2015
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7A97
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![BU of 7a97 by Molmil](/molmil-images/mine/7a97) | SARS-CoV-2 Spike Glycoprotein with 2 ACE2 Bound | Descriptor: | Angiotensin-converting enzyme 2, Spike glycoprotein | Authors: | Benton, D.J, Wrobel, A.G, Rosenthal, P.B, Gamblin, S.J. | Deposit date: | 2020-09-01 | Release date: | 2020-09-16 | Last modified: | 2020-12-16 | Method: | ELECTRON MICROSCOPY (4.4 Å) | Cite: | Receptor binding and priming of the spike protein of SARS-CoV-2 for membrane fusion. Nature, 588, 2020
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8A2Z
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![BU of 8a2z by Molmil](/molmil-images/mine/8a2z) | Cryo-EM structure of F-actin in the Ca2+-ADP nucleotide state. | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | Authors: | Oosterheert, W, Klink, B.U, Belyy, A, Pospich, S, Raunser, S. | Deposit date: | 2022-06-06 | Release date: | 2022-08-10 | Last modified: | 2022-11-23 | Method: | ELECTRON MICROSCOPY (2.15 Å) | Cite: | Structural basis of actin filament assembly and aging. Nature, 611, 2022
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8A2U
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![BU of 8a2u by Molmil](/molmil-images/mine/8a2u) | Cryo-EM structure of F-actin in the Ca2+-ADP-BeF3- nucleotide state. | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | Authors: | Oosterheert, W, Klink, B.U, Belyy, A, Pospich, S, Raunser, S. | Deposit date: | 2022-06-06 | Release date: | 2022-08-10 | Last modified: | 2022-11-23 | Method: | ELECTRON MICROSCOPY (2.21 Å) | Cite: | Structural basis of actin filament assembly and aging. Nature, 611, 2022
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5JOM
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![BU of 5jom by Molmil](/molmil-images/mine/5jom) | X-ray structure of CO-bound sperm whale myoglobin using a fixed target crystallography chip | Descriptor: | CARBON MONOXIDE, Myoglobin, PROTOPORPHYRIN IX CONTAINING FE, ... | Authors: | Oghbaey, S, Sarracini, A, Ginn, H.M, Pare-Labrosse, O, Kuo, A, Marx, A, Epp, S.W, Sherrell, D.A, Eger, B.T, Zhong, Y, Loch, R, Mariani, V, Alonso-Mori, R, Nelson, S, Lemke, H.T, Owen, R.L, Pearson, A.R, Stuart, D.I, Ernst, O.P, Mueller-Werkmeister, H.M, Miller, R.J.D. | Deposit date: | 2016-05-02 | Release date: | 2016-08-17 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Fixed target combined with spectral mapping: approaching 100% hit rates for serial crystallography. Acta Crystallogr D Struct Biol, 72, 2016
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4Y66
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![BU of 4y66 by Molmil](/molmil-images/mine/4y66) | |
8A2Y
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![BU of 8a2y by Molmil](/molmil-images/mine/8a2y) | Cryo-EM structure of F-actin in the Ca2+-ADP-Pi nucleotide state. | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | Authors: | Oosterheert, W, Klink, B.U, Belyy, A, Pospich, S, Raunser, S. | Deposit date: | 2022-06-06 | Release date: | 2022-08-10 | Last modified: | 2022-11-23 | Method: | ELECTRON MICROSCOPY (2.15 Å) | Cite: | Structural basis of actin filament assembly and aging. Nature, 611, 2022
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8A2S
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![BU of 8a2s by Molmil](/molmil-images/mine/8a2s) | Cryo-EM structure of F-actin in the Mg2+-ADP-Pi nucleotide state. | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | Authors: | Oosterheert, W, Klink, B.U, Belyy, A, Pospich, S, Raunser, S. | Deposit date: | 2022-06-06 | Release date: | 2022-08-10 | Last modified: | 2022-11-23 | Method: | ELECTRON MICROSCOPY (2.22 Å) | Cite: | Structural basis of actin filament assembly and aging. Nature, 611, 2022
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1A37
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![BU of 1a37 by Molmil](/molmil-images/mine/1a37) | 14-3-3 PROTEIN ZETA BOUND TO PS-RAF259 PEPTIDE | Descriptor: | 14-3-3 PROTEIN ZETA, PS-RAF259 PEPTIDE LSQRQRST(SEP)TPNVHM | Authors: | Petosa, C, Masters, S.C, Pohl, J, Wang, B, Fu, H, Liddington, R.C. | Deposit date: | 1998-01-28 | Release date: | 1999-03-02 | Last modified: | 2024-06-05 | Method: | X-RAY DIFFRACTION (3.6 Å) | Cite: | 14-3-3zeta binds a phosphorylated Raf peptide and an unphosphorylated peptide via its conserved amphipathic groove. J.Biol.Chem., 273, 1998
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1A3J
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![BU of 1a3j by Molmil](/molmil-images/mine/1a3j) | X-RAY CRYSTALLOGRAPHIC DETERMINATION OF A COLLAGEN-LIKE PEPTIDE WITH THE REPEATING SEQUENCE (PRO-PRO-GLY) | Descriptor: | COLLAGEN-LIKE PEPTIDE | Authors: | Kramer, R.Z, Vitagliano, L, Bella, J, Berisio, R, Mazzarella, L, Brodsky, B, Zagari, A, Berman, H.M. | Deposit date: | 1998-01-22 | Release date: | 1998-05-06 | Last modified: | 2024-06-05 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | X-ray crystallographic determination of a collagen-like peptide with the repeating sequence (Pro-Pro-Gly). J.Mol.Biol., 280, 1998
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8A2R
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![BU of 8a2r by Molmil](/molmil-images/mine/8a2r) | Cryo-EM structure of F-actin in the Mg2+-ADP-BeF3- nucleotide state. | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | Authors: | Oosterheert, W, Klink, B.U, Belyy, A, Pospich, S, Raunser, S. | Deposit date: | 2022-06-06 | Release date: | 2022-08-10 | Last modified: | 2022-11-23 | Method: | ELECTRON MICROSCOPY (2.17 Å) | Cite: | Structural basis of actin filament assembly and aging. Nature, 611, 2022
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7V3I
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![BU of 7v3i by Molmil](/molmil-images/mine/7v3i) | DENV2_NGC_Fab_C10 4degrees (3Fab:3E) | Descriptor: | Envelope protein E, Fab_C10_heavy_chain, Fab_C10_light_chain, ... | Authors: | Shu, B, Zhang, S, Victor, A.K, Ng, T.S, Lok, S.M. | Deposit date: | 2021-08-10 | Release date: | 2021-12-29 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (4.4 Å) | Cite: | Human antibody C10 neutralizes by diminishing Zika but enhancing dengue virus dynamics. Cell, 184, 2021
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7V3J
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![BU of 7v3j by Molmil](/molmil-images/mine/7v3j) | DENV2:F(ab')2-local | Descriptor: | Envelope protein E, Fab_C10_heavy_chain, Fab_C10_light_chain, ... | Authors: | Shu, B, Zhang, S, Victor, A.K, Ng, T.S, Lok, S.M. | Deposit date: | 2021-08-10 | Release date: | 2021-12-29 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (4.9 Å) | Cite: | Human antibody C10 neutralizes by diminishing Zika but enhancing dengue virus dynamics. Cell, 184, 2021
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1AD7
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![BU of 1ad7 by Molmil](/molmil-images/mine/1ad7) | NMR STRUCTURE OF METAL-FREE CONANTOKIN G, 1 STRUCTURE | Descriptor: | CONANTOXIN G | Authors: | Rigby, A.C, Baleja, J.D, Furie, B.C, Furie, B. | Deposit date: | 1997-02-21 | Release date: | 1997-08-20 | Last modified: | 2024-06-05 | Method: | SOLUTION NMR | Cite: | Three-dimensional structure of a gamma-carboxyglutamic acid-containing conotoxin, conantokin G, from the marine snail Conus geographus: the metal-free conformer. Biochemistry, 36, 1997
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6GD8
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![BU of 6gd8 by Molmil](/molmil-images/mine/6gd8) | Cytochrome c in complex with Sulfonato-calix[8]arene, P31 form | Descriptor: | Cytochrome c iso-1, HEME C, sulfonato-calix[8]arene | Authors: | Rennie, M.L, Fox, G.C, Crowley, P.B. | Deposit date: | 2018-04-23 | Release date: | 2018-08-29 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Auto-regulated Protein Assembly on a Supramolecular Scaffold. Angew. Chem. Int. Ed. Engl., 57, 2018
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6BJQ
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![BU of 6bjq by Molmil](/molmil-images/mine/6bjq) | |
6HTI
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![BU of 6hti by Molmil](/molmil-images/mine/6hti) | Crystal structure of Schistosoma mansoni HDAC8 complexed with a benzohydroxamate inhibitor 6 | Descriptor: | GLYCEROL, Histone deacetylase, POTASSIUM ION, ... | Authors: | Shaik, T.B, Marek, M, Romier, C. | Deposit date: | 2018-10-04 | Release date: | 2018-10-31 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.693 Å) | Cite: | Characterization of Histone Deacetylase 8 (HDAC8) Selective Inhibition Reveals Specific Active Site Structural and Functional Determinants. J. Med. Chem., 61, 2018
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7LWL
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![BU of 7lwl by Molmil](/molmil-images/mine/7lwl) | |
5IAS
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![BU of 5ias by Molmil](/molmil-images/mine/5ias) | Caspase 3 V266Y | Descriptor: | ACE-ASP-GLU-VAL-ASK, Caspase-3, SODIUM ION | Authors: | Maciag, J.J, Mackenzie, S.H, Tucker, M.B, Schipper, J.L, Swartz, P.D, Clark, A.C. | Deposit date: | 2016-02-21 | Release date: | 2016-10-26 | Method: | X-RAY DIFFRACTION (1.54 Å) | Cite: | Tunable allosteric library of caspase-3 identifies coupling between conserved water molecules and conformational selection. Proc.Natl.Acad.Sci.USA, 113, 2016
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7LJS
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![BU of 7ljs by Molmil](/molmil-images/mine/7ljs) | Porcine Dihydropyrimidine dehydrogenase (DPD) complexed with 5-Ethynyluracil (5EU) - Open Form | Descriptor: | 5-ethynylpyrimidine-2,4(1H,3H)-dione, Dihydropyrimidine dehydrogenase [NADP(+)], FLAVIN MONONUCLEOTIDE, ... | Authors: | Butrin, A, Forouzesh, D, Beaupre, B, Wawrzak, Z, Liu, D, Moran, G. | Deposit date: | 2021-01-30 | Release date: | 2021-04-07 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The Interaction of Porcine Dihydropyrimidine Dehydrogenase with the Chemotherapy Sensitizer: 5-Ethynyluracil. Biochemistry, 60, 2021
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5EVJ
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![BU of 5evj by Molmil](/molmil-images/mine/5evj) | X-ray crystal structure of CrArsM, an arsenic (III) S-adenosylmethionine methyltransferase from Chlamydomonas reinhardtii | Descriptor: | Arsenite methyltransferase, SODIUM ION | Authors: | Packianathan, C, Kandavelu, P, Sankaran, B, Rosen, B.P. | Deposit date: | 2015-11-19 | Release date: | 2016-11-30 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal structure of CrArsM, an arsenic (III) S-adenosylmethionine methyltransferase from Chlamydomonas reinhardtii To Be Published
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6VO8
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![BU of 6vo8 by Molmil](/molmil-images/mine/6vo8) | X-ray structure of the Cj1427 in the presence of NADH and GDP-D-glycero-D-mannoheptose, an essential NAD-dependent dehydrogenase from Campylobacter jejuni | Descriptor: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, Putative sugar-nucleotide epimerase/dehydratease, [[(2~{R},3~{S},4~{R},5~{R})-5-(2-azanyl-6-oxidanylidene-3~{H}-purin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2~{R},3~{S},4~{S},5~{S},6~{S})-6-[(1~{S})-1,2-bis(oxidanyl)ethyl]-3,4,5-tris(oxidanyl)oxan-2-yl] hydrogen phosphate | Authors: | Spencer, K.D, Anderson, T.K, Thoden, J.B, Huddleston, J.P, Raushel, F.M, Holden, H.M. | Deposit date: | 2020-01-30 | Release date: | 2020-03-25 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural Analysis of Cj1427, an Essential NAD-Dependent Dehydrogenase for the Biosynthesis of the Heptose Residues in the Capsular Polysaccharides ofCampylobacter jejuni. Biochemistry, 59, 2020
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6NL4
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1CCG
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![BU of 1ccg by Molmil](/molmil-images/mine/1ccg) | CONSTRUCTION OF A BIS-AQUO HEME ENZYME AND REPLACEMENT WITH EXOGENOUS LIGAND | Descriptor: | CYTOCHROME C PEROXIDASE, IMIDAZOLE, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Mcree, D.E, Jensen, G.M, Fitzgerald, M.M, Siegel, H.A, Goodin, D.B. | Deposit date: | 1994-05-04 | Release date: | 1994-07-31 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Construction of a bisaquo heme enzyme and binding by exogenous ligands. Proc.Natl.Acad.Sci.USA, 91, 1994
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7C18
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![BU of 7c18 by Molmil](/molmil-images/mine/7c18) | |