6NL4

Crystal structure of Mycobacterium tuberculosis dethiobiotin synthetase in complex with gemcitabine

Summary for 6NL4

• Entry DOI: 10.2210/pdb6nl4/pdb
• Related: 6CVE
• Descriptor: ATP-dependent dethiobiotin synthetase BioD, SULFATE ION, GEMCITABINE, ... (4 entities in total)
• Functional Keywords: enzyme, synthetase, nucleotide triphosphate binding, transferase, transferase-antibiotic complex, transferase/antibiotic
• Biological source: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
• Total number of polymer chains: 4
• Total formula weight: 94316.50

Authors

Thompson, A.P.,Polyak, S.W.,Wegener, K.L.,Bruning, J.B. (deposition date: 2019-01-07, release date: 2020-01-15, Last modification date: 2024-03-13)

• Primary citation: Thompson, A.P.,Polyak, S.W.,Wegener, K.L.,Bruning, J.B.; Crystal structure of Mycobacterium tuberculosis dethiobiotin synthetase in complex with gemcitabine; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.991 Å)