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6UJD
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BU of 6ujd by Molmil
Crystal structure of Cysteine-tRNA ligase from Elizabethkingia sp.
Descriptor: 1,2-ETHANEDIOL, 1-METHOXY-2-[2-(2-METHOXY-ETHOXY]-ETHANE, CHLORIDE ION, ...
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2019-10-02
Release date:2019-10-16
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structure of Cysteine-tRNA ligase from Elizabethkingia sp.
TO BE PUBLISHED
5UAI
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BU of 5uai by Molmil
Crystal structure of Methionyl-tRNA formyltransferase from Pseudomonas aeruginosa
Descriptor: 1,2-ETHANEDIOL, Methionyl-tRNA formyltransferase
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2016-12-19
Release date:2017-01-18
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Crystal structure of Methionyl-tRNA formyltransferase from Pseudomonas aeruginosa
to be published
5TEW
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BU of 5tew by Molmil
Crystal structure of a tryptophanyl-tRNA synthetase from Neisseria gonorrhoeae bound to tryptophan
Descriptor: SULFATE ION, TRYPTOPHAN, Tryptophan--tRNA ligase
Authors:Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2016-09-22
Release date:2016-10-05
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of a tryptophanyl-tRNA synthetase from Neisseria gonorrhoeae bound to tryptophan
To Be Published
3QO7
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BU of 3qo7 by Molmil
Crystal structure of the seryl-tRNA synthetase from Candida albicans
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Seryl-tRNA synthetase, cytoplasmic
Authors:Rocha, R, Santos, M.A, Pereira, P.J.B, Macedo-Ribeiro, S.
Deposit date:2011-02-09
Release date:2011-08-03
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Unveiling the structural basis for translational ambiguity tolerance in a human fungal pathogen.
Proc.Natl.Acad.Sci.USA, 108, 2011
5ZZV
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BU of 5zzv by Molmil
Crystal structure of PEG-1500 crystallized Peptidyl-tRNA Hydrolase from Acinetobacter baumannii at 1.5 A resolution
Descriptor: 1,2-ETHANEDIOL, Peptidyl-tRNA hydrolase
Authors:Bairagya, H.R, Sharma, P, Iqbal, N, Sharma, S, Singh, T.P.
Deposit date:2018-06-04
Release date:2018-06-20
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.57 Å)
Cite:Crystal structure of PEG-1500 crystallized Peptidyl-tRNA Hydrolase from Acinetobacter baumannii at 1.5 A resolution
To Be Published
6AQG
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BU of 6aqg by Molmil
Crystal Structure of Lysyl-tRNA Synthetase from Mycobacterium ulcerans complexed with L-lysine and Cladosporin
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, LYSINE, Lysine--tRNA ligase, ...
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2017-08-19
Release date:2017-08-30
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Crystal Structure of Lysyl-tRNA Synthetase from Mycobacterium ulcerans complexed with L-lysine and Cladosporin
to be published
6AQH
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BU of 6aqh by Molmil
Crystal Structure of Lysyl-tRNA Synthetase from Mycobacterium thermoresistibile complexed with L-lysine and Cladosporin
Descriptor: 1,2-ETHANEDIOL, LYSINE, Lysine--tRNA ligase, ...
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2017-08-19
Release date:2017-08-30
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Crystal Structure of Lysyl-tRNA Synthetase from Mycobacterium thermoresistibile complexed with L-lysine and Cladosporin
to be published
3REX
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BU of 3rex by Molmil
Crystal structure of the archaeal asparagine synthetase A complexed with Adenosine monophosphate
Descriptor: ADENOSINE MONOPHOSPHATE, AsnS-like asparaginyl-tRNA synthetase related protein, MAGNESIUM ION
Authors:Blaise, M, Frechin, M, Charron, C, Roy, H, Sauter, C, Lorber, B, Olieric, V, Kern, D.
Deposit date:2011-04-05
Release date:2011-08-17
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal Structure of the Archaeal Asparagine Synthetase: Interrelation with Aspartyl-tRNA and Asparaginyl-tRNA Synthetases.
J.Mol.Biol., 412, 2011
6C86
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BU of 6c86 by Molmil
Crystal Structure of Lysyl-tRNA Synthetase from Cryptosporidium parvum complexed with L-Lysylsulfamoyl Adenosine
Descriptor: 1,2-ETHANEDIOL, 5'-O-[(L-LYSYLAMINO)SULFONYL]ADENOSINE, CHLORIDE ION, ...
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2018-01-24
Release date:2018-02-28
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Crystal Structure of Lysyl-tRNA Synthetase from Cryptosporidium parvum complexed with L-Lysylsulfamoyl Adenosine
to be published
6CHD
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BU of 6chd by Molmil
Crystal Structure of Human Lysyl-tRNA Synthetase complexed with L-Lysylsulfamoyl Adenosine
Descriptor: 1,2-ETHANEDIOL, 5'-O-[(L-LYSYLAMINO)SULFONYL]ADENOSINE, GLYCEROL, ...
Authors:Dranow, D.M, Abendroth, J, Lorimer, D.D.
Deposit date:2018-02-22
Release date:2018-03-07
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal Structure of Human Lysyl-tRNA Synthetase complexed with L-Lysylsulfamoyl Adenosine
to be published
6UYH
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BU of 6uyh by Molmil
Crystal structure of prolyl-tRNA synthetase from Naegleria fowleri in complex with halofuginone and AMPPNP
Descriptor: 1,2-ETHANEDIOL, 7-bromo-6-chloro-3-{3-[(2R,3S)-3-hydroxypiperidin-2-yl]-2-oxopropyl}quinazolin-4(3H)-one, MAGNESIUM ION, ...
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2019-11-13
Release date:2019-11-27
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Crystal structure of prolyl-tRNA synthetase from Naegleria fowleri in complex with halofuginone and AMPPNP
TO BE PUBLISHED
6BNI
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BU of 6bni by Molmil
Crystal Structure of Lysyl-tRNA Synthetase from Cryptosporidium parvum complexed with L-lysine and Adenosine
Descriptor: 1,2-ETHANEDIOL, ADENOSINE, LYSINE, ...
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2017-11-16
Release date:2018-02-14
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Crystal Structure of Lysyl-tRNA Synthetase from Cryptosporidium parvum complexed with L-lysine and Adenosine
to be published
3REU
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BU of 3reu by Molmil
Crystal structure of the archaeal asparagine synthetase A complexed with L-Aspartic acid and Adenosine triphosphate
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, ASPARTIC ACID, AsnS-like asparaginyl-tRNA synthetase related protein, ...
Authors:Blaise, M, Frechin, M, Charron, C, Roy, H, Sauter, C, Lorber, B, Olieric, V, Kern, D.
Deposit date:2011-04-05
Release date:2011-08-17
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal Structure of the Archaeal Asparagine Synthetase: Interrelation with Aspartyl-tRNA and Asparaginyl-tRNA Synthetases.
J.Mol.Biol., 412, 2011
8POR
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BU of 8por by Molmil
Crystal structure of wolbachia leucyl-tRNA synthetase editing domain bound to cmpd6-AMP adduct
Descriptor: 1,2-ETHANEDIOL, 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, Leucine--tRNA ligase, ...
Authors:Palencia, A, Lukarska, M.
Deposit date:2023-07-05
Release date:2024-06-12
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Targeting A Microbiota Wolbachian Aminoacyl-tRNA Synthetase To Block Its Pathogenic Host
Science Advances, 2024
6BLJ
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BU of 6blj by Molmil
Crystal structure of cytoplasmic Serine-tRNA ligase from Naegleria fowleri in complex with AMP
Descriptor: 1,2-ETHANEDIOL, ADENOSINE MONOPHOSPHATE, Serine-tRNA ligase
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2017-11-10
Release date:2017-12-20
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of cytoplasmic Serine-tRNA ligase from Neisseria fowlerii in complex with AMP
TO BE PUBLISHED
6CML
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BU of 6cml by Molmil
Trypanosoma brucei methionyl-tRNA synthetase in complex with inhibitor (Chem 2093)
Descriptor: 1-[(5-chloro-1H-imidazo[4,5-b]pyridin-2-yl)methyl]-4-[(2-chloro-4-methoxyphenyl)methyl]-3-ethyl-1,3-dihydro-2H-imidazol-2-one, GLYCEROL, METHIONINE, ...
Authors:Barros-Alvarez, X, Hol, W.G.J.
Deposit date:2018-03-05
Release date:2019-03-13
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structure-guided discovery of selective methionyl-tRNA synthetase inhibitors with potent activity against Trypanosoma brucei
Rsc Med Chem, 11, 2020
3PZ0
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BU of 3pz0 by Molmil
The crystal structure of AaLeuRS-CP1
Descriptor: CALCIUM ION, Leucyl-tRNA synthetase subunit alpha
Authors:Liu, R.J, Wang, E.D.
Deposit date:2010-12-13
Release date:2011-08-24
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Peripheral insertion modulates the editing activity of the isolated CP1 domain of leucyl-tRNA synthetase
Biochem.J., 440, 2011
2EL9
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BU of 2el9 by Molmil
Crystal structure of E.coli Histidyl-tRNA synthetase complexed with a histidyl-adenylate analogue
Descriptor: 5'-O-[(L-HISTIDYLAMINO)SULFONYL]ADENOSINE, Histidyl-tRNA synthetase
Authors:Yanagisawa, T, Si, S.Y, Matsuno, M, Ishii, R, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2007-03-27
Release date:2008-03-18
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structure of E.coli Histidyl-tRNA synthetase complexed with a histidyl-adenylate analogue
To be published
3RF1
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BU of 3rf1 by Molmil
The crystal structure of glycyl-tRNA synthetase subunit alpha from Campylobacter jejuni subsp. jejuni NCTC 11168
Descriptor: (2S)-2-hydroxybutanedioic acid, GLYCEROL, Glycyl-tRNA synthetase alpha subunit
Authors:Tan, K, Zhang, R, Zhou, M, Hasseman, J, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2011-04-05
Release date:2011-04-20
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The crystal structure of glycyl-tRNA synthetase subunit alpha from Campylobacter jejuni subsp. jejuni NCTC 11168
To be Published
3RGL
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BU of 3rgl by Molmil
The crystal structure of glycyl-tRNA synthetase subunit alpha from Campylobacter jejuni subsp. jejuni NCTC in complex with ATP and glycine
Descriptor: (2S)-2-hydroxybutanedioic acid, ADENOSINE-5'-TRIPHOSPHATE, GLYCINE, ...
Authors:Tan, K, Zhang, R, Zhou, M, Kwon, K, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2011-04-08
Release date:2011-06-08
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:The crystal structure of glycyl-tRNA synthetase subunit alpha from Campylobacter jejuni subsp. jejuni NCTC in complex with ATP and glycine.
To be Published
3R8X
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BU of 3r8x by Molmil
Crystal Structure of Methionyl-tRNA Formyltransferase from Yersinia pestis complexed with L-methionine
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, GLYCEROL, METHIONINE, ...
Authors:Maltseva, N, Kim, Y, Hasseman, J, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2011-03-24
Release date:2011-04-13
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.256 Å)
Cite:Crystal Structure of Methionyl-tRNA Formyltransferase from Yersinia pestis complexed with L-methionine
To be Published
3SZ3
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BU of 3sz3 by Molmil
Crystal structure of Tryptophanyl-tRNA synthetase from Vibrio cholerae with an endogenous tryptophan
Descriptor: GLYCEROL, TRYPTOPHAN, Tryptophanyl-tRNA synthetase
Authors:Cooper, D.R, Kudritska, M, Chruszcz, M, Savchenko, A, Anderson, W.F, Minor, W, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2011-07-18
Release date:2011-09-14
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Crystal structure of Tryptophanyl-tRNA synthetase from Vibrio cholerae with an endogenous tryptophan
To be Published
4P3O
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BU of 4p3o by Molmil
Structural Basis for Full-Spectrum Inhibition of Threonyl-tRNA Synthetase by Borrelidin 2
Descriptor: (1R,2R)-2-[(2S,4E,6E,8R,9S,11R,13S,15S,16S)-7-cyano-8,16-dihydroxy-9,11,13,15-tetramethyl-18-oxooxacyclooctadeca-4,6-dien-2-yl]cyclopentanecarboxylic acid, GLYCEROL, Threonine--tRNA ligase, ...
Authors:Fang, P, Yu, X, Chen, K, Chen, X, Guo, M.
Deposit date:2014-03-09
Release date:2015-03-11
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.505 Å)
Cite:Structural basis for full-spectrum inhibition of translational functions on a tRNA synthetase.
Nat Commun, 6, 2015
4P3P
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BU of 4p3p by Molmil
Structural Basis for Full-Spectrum Inhibition of Threonyl-tRNA Synthetase by Borrelidin 3
Descriptor: (1R,2R)-2-[(2S,4E,6E,8R,9S,11R,13S,15S,16S)-7-cyano-8,16-dihydroxy-9,11,13,15-tetramethyl-18-oxooxacyclooctadeca-4,6-dien-2-yl]cyclopentanecarboxylic acid, GLYCEROL, Threonine--tRNA ligase, ...
Authors:Fang, P, Yu, X, Chen, K, Chen, X, Guo, M.
Deposit date:2014-03-09
Release date:2015-03-11
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural basis for full-spectrum inhibition of translational functions on a tRNA synthetase.
Nat Commun, 6, 2015
4P3N
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BU of 4p3n by Molmil
Structural Basis for Full-Spectrum Inhibition of Threonyl-tRNA Synthetase by Borrelidin 1
Descriptor: (1R,2R)-2-[(2S,4E,6E,8R,9S,11R,13S,15S,16S)-7-cyano-8,16-dihydroxy-9,11,13,15-tetramethyl-18-oxooxacyclooctadeca-4,6-dien-2-yl]cyclopentanecarboxylic acid, Threonine--tRNA ligase, cytoplasmic, ...
Authors:Fang, P, Yu, X, Chen, K, Chen, X, Guo, M.
Deposit date:2014-03-09
Release date:2015-03-11
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural basis for full-spectrum inhibition of translational functions on a tRNA synthetase.
Nat Commun, 6, 2015

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數據於2024-07-10公開中

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