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5YEL	Crystal structure of CTCF ZFs6-11-gb7CSE Descriptor: DNA (26-MER), Transcriptional repressor CTCF, ZINC ION Authors: Yin, M, Wang, J, Wang, M, Li, X, Wang, Y. Deposit date: 2017-09-18 Release date: 2017-11-29 Last modified: 2024-03-27 Method: X-RAY DIFFRACTION (2.96 Å) Cite: Molecular mechanism of directional CTCF recognition of a diverse range of genomic sites Cell Res., 27, 2017
5YEF	Crystal structure of CTCF ZFs2-8-Hs5-1aE Descriptor: DNA (27-MER), Transcriptional repressor CTCF, ZINC ION Authors: Yin, M, Wang, J, Wang, M, Li, X, Wang, Y. Deposit date: 2017-09-17 Release date: 2017-11-29 Last modified: 2024-03-27 Method: X-RAY DIFFRACTION (2.807 Å) Cite: Molecular mechanism of directional CTCF recognition of a diverse range of genomic sites Cell Res., 27, 2017
5WJ7	Crystal Structure of Amino Acids 1733-1797 of Human Beta Cardiac Myosin Fused to Xrcc4 Descriptor: DNA repair protein XRCC4,Myosin-7 Authors: Andreas, M.P, Ajay, G, Gellings, J, Rayment, I. Deposit date: 2017-07-21 Release date: 2017-08-09 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Design considerations in coiled-coil fusion constructs for the structural determination of a problematic region of the human cardiac myosin rod. J. Struct. Biol., 200, 2017
5CY2	Tn3 resolvase - site III complex crystal form II Descriptor: DNA (27-MER), Transposon Tn3 resolvase Authors: Montano, P.S, Rice, P.A. Deposit date: 2015-07-30 Release date: 2017-01-11 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (4 Å) Cite: Structures of resolvase - accessory site complexes To Be Published
377D	5'-R(*CP*GP*UP*AP*CP*DG)-3' Descriptor: RNA-DNA (5'-R(*CP*GP*UP*AP*CP*DG)-3') Authors: Biswas, R, Mitra, S.N, Sundaralingam, M. Deposit date: 1998-01-26 Release date: 1998-08-10 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (1.76 Å) Cite: 1.76 A structure of a pyrimidine start alternating A-RNA hexamer r(CGUAC)dG. Acta Crystallogr.,Sect.D, 54, 1998
7V9X	Cryo-EM structure of E.coli retron-Ec86 in complex with its effector at 2.8 angstrom Descriptor: DNA (105-MER), RNA (14-MER), RNA (81-MER), ... Authors: Wang, Y.J, Guan, Z.Y, Zou, T.T. Deposit date: 2021-08-27 Release date: 2022-08-31 Last modified: 2024-06-19 Method: ELECTRON MICROSCOPY (2.82 Å) Cite: Structural insight into anti-phage Retron-Ec86 complex To Be Published
6YCV	2'-F-riboguanosine and LNA modified hybrid type G-quadruplex with V-loop Descriptor: DNA (5'-D(*GP*GP*GP*AP*TP*GP*GP*GP*AP*CP*AP*CP*AP*(GF2))-R(P*(LCG))-D(P*GP*GP*AP*CP*GP*GP*G)-3') Authors: Weisz, K, Haase, L. Deposit date: 2020-03-19 Release date: 2020-09-02 Last modified: 2024-05-15 Method: SOLUTION NMR Cite: Locked nucleic acid building blocks as versatile tools for advanced G-quadruplex design. Nucleic Acids Res., 48, 2020
6YEP	LNA modified G-quadruplex with flipped G-tract and central tetrad Descriptor: DNA (5'-D(*GP*GP*GP*AP*TP*GP*GP*GP*AP*CP*AP*CP*AP*G)-R(P*(LCG))-D(P*GP*GP*AP*CP*GP*GP*G)-3') Authors: Weisz, K, Haase, L. Deposit date: 2020-03-25 Release date: 2020-09-02 Last modified: 2024-05-15 Method: SOLUTION NMR Cite: Locked nucleic acid building blocks as versatile tools for advanced G-quadruplex design. Nucleic Acids Res., 48, 2020
393D	CRYSTAL STRUCTURE OF TWO SELF-COMPLEMENTARY CHIMERIC DECAMER D(CCGG)R(C)D(GCCGG) AND D(CCGG)R(CG)D(CCGG) Descriptor: DNA/RNA (5'-D(*CP*CP*GP*GP)-R(*CP)-D(*GP*CP*CP*GP*G)-3') Authors: Ban, C, Sundaralingam, M, Ramakrishnan, B. Deposit date: 1998-04-29 Release date: 1998-05-01 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2 Å) Cite: Crystal Structure of Two Self-Complementary Chimeric Decamer d(CCGG)r(C)d(GCCGG) and d(CCGG)r(CG)d(CCGG) To be Published
7W68	human single hexameric Mcm2-7 complex Descriptor: DNA replication licensing factor MCM2, DNA replication licensing factor MCM3, DNA replication licensing factor MCM4, ... Authors: Xu, N.N, Lin, Q.P, Liu, C.D, Tian, H.L, Xiang, Y, Zhu, G. Deposit date: 2021-12-01 Release date: 2023-03-08 Method: ELECTRON MICROSCOPY (4.4 Å) Cite: human single hexameric Mcm2-7 complex To Be Published
6ZL2	Structure of a parallel c-Myc modified with 3' duplex stem-loop overhang Descriptor: DNA (36-MER) Authors: Vianney, Y.M, Weisz, K. Deposit date: 2020-06-30 Release date: 2020-10-07 Last modified: 2024-05-15 Method: SOLUTION NMR Cite: Quadruplex-Duplex Junction: A High-Affinity Binding Site for Indoloquinoline Ligands. Chemistry, 26, 2020
7KBV	Solution structure of the major MYC promoter G-quadruplex with a wild-type flanking sequence Descriptor: Myc2345 Authors: Dickerhoff, J, Yang, D. Deposit date: 2020-10-03 Release date: 2021-06-23 Last modified: 2024-05-01 Method: SOLUTION NMR Cite: Structural recognition of the MYC promoter G-quadruplex by a quinoline derivative: insights into molecular targeting of parallel G-quadruplexes. Nucleic Acids Res., 49, 2021
7KBW	Solution structure of the major MYC promoter G-quadruplex with a wild-type flanking in complex with NSC85697, a quinoline derivative Descriptor: 2-[(~{E})-2-(3-methoxy-4-oxidanyl-phenyl)ethenyl]-1-methyl-quinoline-4-carboxamide, Myc2345 Authors: Dickerhoff, J, Yang, D. Deposit date: 2020-10-03 Release date: 2021-06-23 Last modified: 2024-05-01 Method: SOLUTION NMR Cite: Structural recognition of the MYC promoter G-quadruplex by a quinoline derivative: insights into molecular targeting of parallel G-quadruplexes. Nucleic Acids Res., 49, 2021
7KBX	Solution structure of the major MYC promoter G-quadruplex in complex with NSC85697, a quinoline derivative Descriptor: 2-[(~{E})-2-(3-methoxy-4-oxidanyl-phenyl)ethenyl]-1-methyl-quinoline-4-carboxamide, Myc2345_T23 Authors: Dickerhoff, J, Yang, D. Deposit date: 2020-10-03 Release date: 2021-06-23 Last modified: 2024-05-01 Method: SOLUTION NMR Cite: Structural recognition of the MYC promoter G-quadruplex by a quinoline derivative: insights into molecular targeting of parallel G-quadruplexes. Nucleic Acids Res., 49, 2021
6ZL9	Structure of a parallel c-Myc modified with 5' duplex stem-loop overhang Descriptor: DNA (35-MER) Authors: Vianney, Y.M, Weisz, K. Deposit date: 2020-06-30 Release date: 2020-10-07 Last modified: 2024-06-19 Method: SOLUTION NMR Cite: Quadruplex-Duplex Junction: A High-Affinity Binding Site for Indoloquinoline Ligands. Chemistry, 26, 2020
1Y14	Crystal structure of yeast subcomplex of Rpb4 and Rpb7 Descriptor: DNA-directed RNA polymerase II 19 kDa polypeptide, DNA-directed RNA polymerase II 32 kDa polypeptide Authors: Armache, K.-J, Mitterweger, S, Meinhart, A, Cramer, P. Deposit date: 2004-11-17 Release date: 2004-12-14 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Structures of Complete RNA Polymerase II and Its Subcomplex, Rpb4/7 J.Biol.Chem., 280, 2005
1YNJ	Taq RNA polymerase-Sorangicin complex Descriptor: DNA-directed RNA polymerase alpha chain, DNA-directed RNA polymerase beta chain, DNA-directed RNA polymerase beta' chain, ... Authors: Campbell, E.A, Pavlova, O, Zenkin, N, Leon, F, Irschik, H, Jansen, R, Severinov, K, Darst, S.A. Deposit date: 2005-01-24 Release date: 2005-03-15 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (3.2 Å) Cite: Structural, functional, and genetic analysis of sorangicin inhibition of bacterial RNA polymerase Embo J., 24, 2005
1YNN	Taq RNA polymerase-rifampicin complex Descriptor: DNA-directed RNA polymerase alpha chain, DNA-directed RNA polymerase beta chain, DNA-directed RNA polymerase beta' chain, ... Authors: Campbell, E.A, Pavlova, O, Zenkin, N, Leon, F, Irschik, H, Jansen, R, Severinov, K, Darst, S.A. Deposit date: 2005-01-24 Release date: 2005-03-15 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (3.3 Å) Cite: Structural, functional, and genetic analysis of sorangicin inhibition of bacterial RNA polymerase Embo J., 24, 2005
8VG2	Cryo-EM structure of FoxA1 and GATA4 in complex with H14 chromatosome Descriptor: DNA (196-MER), Hepatocyte nuclear factor 3-alpha, Histone H1.4, ... Authors: Zhou, B.R, Bai, Y. Deposit date: 2023-12-22 Release date: 2024-08-07 Method: ELECTRON MICROSCOPY (3.04 Å) Cite: Cryo-EM structure of FoxA1 and GATA4 in complex with H14 chromatosome Mol.Cell, 2024
7XUR	The cryo-EM structure of human mini-SNAPc in complex with hU6-1 PSE Descriptor: DNA (35-MER), ZINC ION, snRNA-activating protein complex subunit 1, ... Authors: Wang, W, Sun, J.F. Deposit date: 2022-05-19 Release date: 2022-12-07 Last modified: 2024-07-03 Method: ELECTRON MICROSCOPY (3.49 Å) Cite: Structural basis of human SNAPc recognizing proximal sequence element of snRNA promoter. Nat Commun, 13, 2022
2LO6	Structure of Nrd1 CID bound to phosphorylated RNAP II CTD Descriptor: DNA-directed RNA polymerase II subunit RPB1, Protein NRD1 Authors: Kubicek, K, Cerna, H, Pasulka, J, Holub, P, Hrossova, D, Loehr, F, Hofr, C, Vanacova, S, Stefl, R. Deposit date: 2012-01-17 Release date: 2012-12-26 Method: SOLUTION NMR Cite: Serine phosphorylation and proline isomerization in RNAP II CTD control recruitment of Nrd1. Genes Dev., 26, 2012
4JBK	Molecular basis for abrogation of activation of pro-inflammatory cytokines Descriptor: DNA (5'-D(P*GP*GP*AP*AP*TP*TP*AP*TP*AP*AP*TP*TP*CP*C)-3'), Interferon-activable protein 202 Authors: Ru, H, Ni, X, Crowley, C, Zhao, L, Ding, W, Hung, L.-W, Shaw, N, Cheng, G, Liu, Z.-J. Deposit date: 2013-02-19 Release date: 2013-06-26 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.963 Å) Cite: Structural basis for termination of AIM2-mediated signaling by p202 Cell Res., 23, 2013
7B3C	Structure of elongating SARS-CoV-2 RNA-dependent RNA polymerase with Remdesivir at position -4 (structure 2) Descriptor: DNA/RNA (5'-R(P*CP*UP*AP*CP*GP*CP*A)-D(P*(RMP))-R(P*GP*UP*G)-3'), Non-structural protein 7, Non-structural protein 8, ... Authors: Kokic, G, Hillen, H.S, Tegunov, D, Dienemann, C, Seitz, F, Schmitzova, J, Farnung, L, Siewert, A, Hoebartner, C, Cramer, P. Deposit date: 2020-11-30 Release date: 2020-12-23 Last modified: 2024-07-10 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: Mechanism of SARS-CoV-2 polymerase stalling by remdesivir. Nat Commun, 12, 2021
7B3B	Structure of elongating SARS-CoV-2 RNA-dependent RNA polymerase with Remdesivir at position -3 (structure 1) Descriptor: DNA/RNA (5'-R(P*CP*UP*AP*CP*GP*CP*G)-D(P*(RMP))-R(P*UP*G)-3'), Non-structural protein 7, Non-structural protein 8, ... Authors: Kokic, G, Hillen, H.S, Tegunov, D, Dienemann, C, Seitz, F, Schmitzova, J, Farnung, L, Siewert, A, Hoebartner, C, Cramer, P. Deposit date: 2020-11-30 Release date: 2020-12-23 Last modified: 2024-07-10 Method: ELECTRON MICROSCOPY (3.1 Å) Cite: Mechanism of SARS-CoV-2 polymerase stalling by remdesivir. Nat Commun, 12, 2021
118D	CRYSTAL AND MOLECULAR STRUCTURE OF D(GTGCGCAC): INVESTIGATION OF THE EFFECTS OF BASE SEQUENCE ON THE CONFORMATION OF OCTAMER DUPLEXES Descriptor: DNA (5'-D(*GP*TP*GP*CP*GP*CP*AP*C)-3') Authors: Bingman, C.A, Li, X, Zon, G, Sundaralingam, M. Deposit date: 1993-02-11 Release date: 1993-02-11 Last modified: 2023-03-22 Method: X-RAY DIFFRACTION (1.64 Å) Cite: Crystal and molecular structure of d(GTGCGCAC): investigation of the effects of base sequence on the conformation of octamer duplexes. Biochemistry, 31, 1992

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