PDB: 93737 resultsInfo pagesStatus searchChemie searchBIRD

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1TYE	Structural basis for allostery in integrins and binding of ligand-mimetic therapeutics to the platelet receptor for fibrinogen Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CACODYLATE ION, CALCIUM ION, ... Authors: Xiao, T, Takagi, J, Coller, B.S, Wang, J.-H, Springer, T.A. Deposit date: 2004-07-07 Release date: 2004-10-12 Last modified: 2024-10-09 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Structural basis for allostery in integrins and binding to fibrinogen-mimetic therapeutics Nature, 432, 2004
2Q7J	The Wild Type Androgen Receptor Ligand Binding Domain Bound with Testosterone and a TIF2 box 3 Coactivator Peptide 740-753 Descriptor: Androgen receptor, GLYCEROL, Nuclear receptor coactivator 2, ... Authors: Gampe, R.T. Deposit date: 2007-06-07 Release date: 2007-07-24 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Modulation of androgen receptor activation function 2 by testosterone and dihydrotestosterone. J.Biol.Chem., 282, 2007
1GGM	GLYCYL-TRNA SYNTHETASE FROM THERMUS THERMOPHILUS COMPLEXED WITH GLYCYL-ADENYLATE Descriptor: GLYCYL-ADENOSINE-5'-PHOSPHATE, Glycine--tRNA ligase Authors: Arnez, J.G, Moras, D. Deposit date: 1999-01-27 Release date: 1999-01-28 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (3.4 Å) Cite: Glycyl-tRNA synthetase uses a negatively charged pit for specific recognition and activation of glycine. J.Mol.Biol., 286, 1999
2Q7K	The Androgen Receptor Prostate Cancer Mutant H874Y Ligand Binding Domain Bound with Testosterone and an AR 20-30 Peptide Descriptor: Androgen receptor, GLYCEROL, SULFATE ION, ... Authors: Gampe, R.T. Deposit date: 2007-06-07 Release date: 2007-07-24 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Modulation of androgen receptor activation function 2 by testosterone and dihydrotestosterone. J.Biol.Chem., 282, 2007
3TCF	Crystal structure of E. coli OppA complexed with endogenous ligands Descriptor: Endogenous peptide, Periplasmic oligopeptide-binding protein Authors: Klepsch, M.M, Kovermann, M, Low, C, Balbach, J, de Gier, J.W, Slotboom, D.J, Berntsson, R.P.-A. Deposit date: 2011-08-09 Release date: 2011-10-12 Last modified: 2024-10-30 Method: X-RAY DIFFRACTION (2 Å) Cite: Escherichia coli peptide binding protein OppA has a preference for positively charged peptides. J.Mol.Biol., 414, 2011
3BUN	Crystal structure of c-Cbl-TKB domain complexed with its binding motif in Sprouty4 Descriptor: 13-meric peptide from Protein sprouty homolog 4, E3 ubiquitin-protein ligase CBL Authors: Ng, C, Jackson, R.A, Buschdorf, J.P, Sun, Q, Guy, G.R, Sivaraman, J. Deposit date: 2008-01-03 Release date: 2008-02-26 Last modified: 2024-10-30 Method: X-RAY DIFFRACTION (2 Å) Cite: Structural basis for a novel intrapeptidyl H-bond and reverse binding of c-Cbl-TKB domain substrates Embo J., 27, 2008
3BUX	Crystal structure of c-Cbl-TKB domain complexed with its binding motif in c-Met Descriptor: 13-meric peptide from Hepatocyte growth factor receptor, E3 ubiquitin-protein ligase CBL Authors: Ng, C, Jackson, R.A, Buschdorf, J.P, Sun, Q, Guy, G.R, Sivaraman, J. Deposit date: 2008-01-03 Release date: 2008-02-26 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (1.35 Å) Cite: Structural basis for a novel intrapeptidyl H-bond and reverse binding of c-Cbl-TKB domain substrates Embo J., 27, 2008
3BUW	Crystal structure of c-Cbl-TKB domain complexed with its binding motif in Syk Descriptor: 13-meric peptide from Tyrosine-protein kinase SYK, E3 ubiquitin-protein ligase CBL Authors: Ng, C, Jackson, R.A, Buschdorf, J.P, Sun, Q, Guy, G.R, Sivaraman, J. Deposit date: 2008-01-03 Release date: 2008-02-26 Last modified: 2024-11-13 Method: X-RAY DIFFRACTION (1.45 Å) Cite: Structural basis for a novel intrapeptidyl H-bond and reverse binding of c-Cbl-TKB domain substrates Embo J., 27, 2008
2ZEQ	Crystal structure of ubiquitin-like domain of murine Parkin Descriptor: E3 ubiquitin-protein ligase parkin Authors: Tomoo, K. Deposit date: 2007-12-14 Release date: 2008-08-19 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (1.65 Å) Cite: Crystal structure and molecular dynamics simulation of ubiquitin-like domain of murine parkin Biochim.Biophys.Acta, 1784, 2008
1SVV	Initial Stuctural Analysis of Leishmania major Threonine Aldolase Descriptor: THREONINE ALDOLASE, UNKNOWN LIGAND Authors: Hol, W.G.J, Robien, M.A, Structural Genomics of Pathogenic Protozoa Consortium (SGPP) Deposit date: 2004-03-30 Release date: 2004-08-17 Last modified: 2024-11-13 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Initial Structural Analysis of Leishmania major Threonine Aldolase To be Published
4JYJ	Crystal Structure of putative enoyl-CoA hydratase/isomerase from Novosphingobium aromaticivorans DSM 12444 Descriptor: Enoyl-CoA hydratase/isomerase, UNKNOWN LIGAND Authors: Cooper, D.R, Porebski, P.J, Domagalski, M.J, Ahmed, M, Stead, M, Hillerich, B, Seidel, R, Zimmerman, M, Bonanno, J.B, Almo, S.C, Minor, W, New York Structural Genomics Research Consortium (NYSGRC) Deposit date: 2013-03-29 Release date: 2013-05-29 Last modified: 2022-04-13 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Crystal Structure of putative enoyl-CoA hydratase/isomerase from Novosphingobium aromaticivorans DSM 12444 To be Published
3BUO	Crystal structure of c-Cbl-TKB domain complexed with its binding motif in EGF receptor' Descriptor: 13-meric peptide from Epidermal growth factor receptor, E3 ubiquitin-protein ligase CBL Authors: Ng, C, Jackson, R.A, Buschdorf, J.P, Sun, Q, Guy, G.R, Sivaraman, J. Deposit date: 2008-01-03 Release date: 2008-02-26 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Structural basis for a novel intrapeptidyl H-bond and reverse binding of c-Cbl-TKB domain substrates Embo J., 27, 2008
2GFE	Crystal structure of the GluR2 A476E S673D Ligand Binding Core Mutant at 1.54 Angstroms Resolution Descriptor: GLUTAMIC ACID, Glutamate receptor 2, ZINC ION Authors: Mayer, M.L. Deposit date: 2006-03-21 Release date: 2006-08-22 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (1.54 Å) Cite: Interdomain interactions in AMPA and kainate receptors regulate affinity for glutamate. J.Neurosci., 26, 2006
1BTC	THREE-DIMENSIONAL STRUCTURE OF SOYBEAN BETA-AMYLASE DETERMINED AT 3.0 ANGSTROMS RESOLUTION: PRELIMINARY CHAIN TRACING OF THE COMPLEX WITH ALPHA-CYCLODEXTRIN Descriptor: BETA-AMYLASE, BETA-MERCAPTOETHANOL, Cyclohexakis-(1-4)-(alpha-D-glucopyranose), ... Authors: Mikami, B, Hehre, E.J, Sato, M, Katsube, Y, Hirose, M, Morita, Y, Sacchettini, J.C. Deposit date: 1993-02-18 Release date: 1993-10-31 Last modified: 2020-07-29 Method: X-RAY DIFFRACTION (2 Å) Cite: The 2.0-A resolution structure of soybean beta-amylase complexed with alpha-cyclodextrin. Biochemistry, 32, 1993
1IM6	CRYSTAL STRUCTURE OF UNLIGATED HPPK(R82A) FROM E.COLI AT 1.74 ANGSTROM RESOLUTION Descriptor: 6-HYDROXYMETHYL-7,8-DIHYDROPTERIN PYROPHOSPHOKINASE, CHLORIDE ION Authors: Blaszczyk, J, Ji, X. Deposit date: 2001-05-09 Release date: 2003-04-15 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (1.74 Å) Cite: Dynamic Roles of Arginine Residues 82 and 92 of Escherichia coli 6-Hydroxymethyl-7,8-dihydropterin Pyrophosphokinase: Crystallographic Studies Biochemistry, 42, 2003
8I95	Structure of EP54-C3aR-Go complex Descriptor: Antibody fragment - ScFv16, C3a anaphylatoxin chemotactic receptor, EP54 ligand, ... Authors: Yadav, M.K, Yadav, R, Maharana, J, Sarma, P, Banerjee, R, Shukla, A.K, Gati, C. Deposit date: 2023-02-06 Release date: 2023-10-18 Last modified: 2023-11-08 Method: ELECTRON MICROSCOPY (2.88 Å) Cite: Molecular basis of anaphylatoxin binding, activation, and signaling bias at complement receptors. Cell, 186, 2023
8I9A	Structure of EP54-C3aR-Gq complex Descriptor: Antibody fragment - ScFv16, C3a anaphylatoxin chemotactic receptor, EP54 ligand, ... Authors: Yadav, M.K, Yadav, R, Maharana, J, Sarma, P, Banerjee, R, Shukla, A.K, Gati, C. Deposit date: 2023-02-06 Release date: 2023-10-18 Last modified: 2024-10-16 Method: ELECTRON MICROSCOPY (3.57 Å) Cite: Molecular basis of anaphylatoxin binding, activation, and signaling bias at complement receptors. Cell, 186, 2023
3LCY	Titin Ig tandem domains A164-A165 Descriptor: Titin Authors: Chen, Q, Groves, M.R, Wilmanns, M. Deposit date: 2010-01-12 Release date: 2011-05-25 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Structural investigation of the Titin A-band tandem Ig domains A164-A165 To be Published
3D98	Crystal structure of GlmU from Mycobacterium tuberculosis, ligand-free form Descriptor: Bifunctional protein glmU Authors: Zhang, Z, Squire, C.J, Baker, E.N. Deposit date: 2008-05-27 Release date: 2009-03-10 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Structure and function of GlmU from Mycobacterium tuberculosis. Acta Crystallogr.,Sect.D, 65, 2009
5X8M	PD-L1 in complex with durvalumab Descriptor: Programmed cell death 1 ligand 1, durvalumab heavy chain, durvalumab light chain Authors: Heo, Y.S, Lee, H.T. Deposit date: 2017-03-03 Release date: 2017-08-16 Last modified: 2024-10-23 Method: X-RAY DIFFRACTION (2.661 Å) Cite: Molecular mechanism of PD-1/PD-L1 blockade via anti-PD-L1 antibodies atezolizumab and durvalumab Sci Rep, 7, 2017
5X8L	PD-L1 in complex with atezolizumab Descriptor: Programmed cell death 1 ligand 1, atezolizumab heavy chain, atezolizumab light chain Authors: Heo, Y.S, Lee, H.T. Deposit date: 2017-03-03 Release date: 2017-08-16 Last modified: 2024-11-13 Method: X-RAY DIFFRACTION (3.1 Å) Cite: Molecular mechanism of PD-1/PD-L1 blockade via anti-PD-L1 antibodies atezolizumab and durvalumab Sci Rep, 7, 2017
4XAS	mGluR2 ECD ligand complex Descriptor: (1R,4S,5S,6S)-4-aminospiro[bicyclo[3.1.0]hexane-2,1'-cyclopropane]-4,6-dicarboxylic acid, Metabotropic glutamate receptor 2 Authors: Clawson, D.K. Deposit date: 2014-12-15 Release date: 2015-02-04 Last modified: 2024-10-23 Method: X-RAY DIFFRACTION (2.35 Å) Cite: Synthesis and Pharmacological Characterization of C4-Disubstituted Analogs of 1S,2S,5R,6S-2-Aminobicyclo[3.1.0]hexane-2,6-dicarboxylate: Identification of a Potent, Selective Metabotropic Glutamate Receptor Agonist and Determination of Agonist-Bound Human mGlu2 and mGlu3 Amino Terminal Domain Structures. J.Med.Chem., 58, 2015
3LEE	Crystal structure of the human squalene synthase complexed with BPH-652 Descriptor: (1R)-4-(3-phenoxyphenyl)-1-phosphonobutane-1-sulfonic acid, MAGNESIUM ION, Squalene synthetase Authors: Liu, Y.-L, Lin, F.-Y, Oldfield, E. Deposit date: 2010-01-14 Release date: 2010-12-08 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (3.2 Å) Cite: Mechanism of Action (and Inhibition) of Head-to-Head Terpene Synthases: A Structural Investigation To be Published
6ZBT	Structure of 14-3-3 gamma in complex with Nedd4-2 14-3-3 binding motif Ser342 Descriptor: 1,1,1,3,3,3-hexafluoropropan-2-ol, 14-3-3 protein gamma, E3 ubiquitin-protein ligase NEDD4-like Authors: Joshi, R, Kalabova, D, Obsil, T, Obsilova, V. Deposit date: 2020-06-09 Release date: 2021-07-21 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (1.79948521 Å) Cite: 14-3-3-protein regulates Nedd4-2 by modulating interactions between HECT and WW domains. Commun Biol, 4, 2021
6ZC9	Structure of 14-3-3 gamma in complex with Nedd4-2 14-3-3 binding motif Ser448 Descriptor: 1,1,1,3,3,3-hexafluoropropan-2-ol, 14-3-3 protein gamma, E3 ubiquitin-protein ligase NEDD4-like Authors: Pohl, P, Kalabova, D, Obsil, T, Obsilova, V. Deposit date: 2020-06-10 Release date: 2021-07-21 Last modified: 2024-10-23 Method: X-RAY DIFFRACTION (1.89895988 Å) Cite: 14-3-3-protein regulates Nedd4-2 by modulating interactions between HECT and WW domains. Commun Biol, 4, 2021

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