2Q7K

The Androgen Receptor Prostate Cancer Mutant H874Y Ligand Binding Domain Bound with Testosterone and an AR 20-30 Peptide

Summary for 2Q7K

• Entry DOI: 10.2210/pdb2q7k/pdb
• Descriptor: Androgen receptor, SULFATE ION, TESTOSTERONE, ... (6 entities in total)
• Functional Keywords: androgen receptor prostate cancer mutant h874y ligand binding domain, testoseterone, n-terminal ar peptide, hormone
• Biological source: Homo sapiens (human); More
• Cellular location: Nucleus: P10275 P10275
• Total number of polymer chains: 2
• Total formula weight: 31872.18

Authors

Gampe, R.T. (deposition date: 2007-06-07, release date: 2007-07-24, Last modification date: 2024-02-21)

• Primary citation: Askew, E.B.,Gampe, R.T.,Stanley, T.B.,Faggart, J.L.,Wilson, E.M.; Modulation of androgen receptor activation function 2 by testosterone and dihydrotestosterone.; J.Biol.Chem., 282:25801-25816, 2007; PubMed: 17591767; DOI: 10.1074/jbc.M703268200

Experimental method

X-RAY DIFFRACTION (1.8 Å)